CA1055844A - Feline calicivirus vaccine and production thereof - Google Patents
Feline calicivirus vaccine and production thereofInfo
- Publication number
- CA1055844A CA1055844A CA240,138A CA240138A CA1055844A CA 1055844 A CA1055844 A CA 1055844A CA 240138 A CA240138 A CA 240138A CA 1055844 A CA1055844 A CA 1055844A
- Authority
- CA
- Canada
- Prior art keywords
- feline
- virus
- vaccine
- feline calicivirus
- calicivirus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229960005486 vaccine Drugs 0.000 title claims abstract description 48
- 241000714201 Feline calicivirus Species 0.000 title claims abstract description 47
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 6
- 241000700605 Viruses Species 0.000 claims abstract description 51
- 241000282326 Felis catus Species 0.000 claims abstract description 46
- 241000282324 Felis Species 0.000 claims abstract description 37
- 238000000034 method Methods 0.000 claims description 30
- 208000015181 infectious disease Diseases 0.000 claims description 20
- 239000012530 fluid Substances 0.000 claims description 19
- 230000002238 attenuated effect Effects 0.000 claims description 17
- 230000002458 infectious effect Effects 0.000 claims description 14
- 201000010099 disease Diseases 0.000 claims description 13
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 13
- 235000015097 nutrients Nutrition 0.000 claims description 10
- 238000011534 incubation Methods 0.000 claims description 8
- 239000002609 medium Substances 0.000 claims description 8
- 230000003053 immunization Effects 0.000 claims description 7
- 231100000252 nontoxic Toxicity 0.000 claims description 7
- 230000003000 nontoxic effect Effects 0.000 claims description 7
- 239000002054 inoculum Substances 0.000 claims description 5
- 230000001902 propagating effect Effects 0.000 claims description 5
- 208000024891 symptom Diseases 0.000 claims description 5
- 238000003306 harvesting Methods 0.000 claims description 4
- 239000007787 solid Substances 0.000 claims description 4
- 238000001035 drying Methods 0.000 claims description 3
- 238000004113 cell culture Methods 0.000 claims description 2
- 239000001963 growth medium Substances 0.000 claims description 2
- 230000001575 pathological effect Effects 0.000 claims description 2
- 230000001681 protective effect Effects 0.000 claims description 2
- 230000001609 comparable effect Effects 0.000 claims 1
- 230000004936 stimulating effect Effects 0.000 claims 1
- 206010057190 Respiratory tract infections Diseases 0.000 abstract description 2
- 238000012986 modification Methods 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 description 16
- 230000000120 cytopathologic effect Effects 0.000 description 9
- 230000003612 virological effect Effects 0.000 description 8
- 238000002360 preparation method Methods 0.000 description 6
- 150000002500 ions Chemical class 0.000 description 5
- 210000001331 nose Anatomy 0.000 description 5
- 238000002255 vaccination Methods 0.000 description 5
- 230000005875 antibody response Effects 0.000 description 4
- 210000003734 kidney Anatomy 0.000 description 4
- 230000000241 respiratory effect Effects 0.000 description 4
- 239000003104 tissue culture media Substances 0.000 description 4
- 230000015572 biosynthetic process Effects 0.000 description 3
- 238000010790 dilution Methods 0.000 description 3
- 239000012895 dilution Substances 0.000 description 3
- 210000001508 eye Anatomy 0.000 description 3
- 238000004108 freeze drying Methods 0.000 description 3
- 238000002649 immunization Methods 0.000 description 3
- 238000002955 isolation Methods 0.000 description 3
- PLFFHJWXOGYWPR-HEDMGYOXSA-N (4r)-4-[(3r,3as,5ar,5br,7as,11as,11br,13ar,13bs)-5a,5b,8,8,11a,13b-hexamethyl-1,2,3,3a,4,5,6,7,7a,9,10,11,11b,12,13,13a-hexadecahydrocyclopenta[a]chrysen-3-yl]pentan-1-ol Chemical compound C([C@]1(C)[C@H]2CC[C@H]34)CCC(C)(C)[C@@H]1CC[C@@]2(C)[C@]4(C)CC[C@@H]1[C@]3(C)CC[C@@H]1[C@@H](CCCO)C PLFFHJWXOGYWPR-HEDMGYOXSA-N 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- 206010037660 Pyrexia Diseases 0.000 description 2
- 235000017276 Salvia Nutrition 0.000 description 2
- 241001072909 Salvia Species 0.000 description 2
- 230000005540 biological transmission Effects 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 230000001605 fetal effect Effects 0.000 description 2
- 230000027950 fever generation Effects 0.000 description 2
- 238000002347 injection Methods 0.000 description 2
- 239000007924 injection Substances 0.000 description 2
- 238000011081 inoculation Methods 0.000 description 2
- 210000003292 kidney cell Anatomy 0.000 description 2
- 230000005923 long-lasting effect Effects 0.000 description 2
- 210000004072 lung Anatomy 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 239000006199 nebulizer Substances 0.000 description 2
- 238000007911 parenteral administration Methods 0.000 description 2
- 230000000644 propagated effect Effects 0.000 description 2
- 210000002345 respiratory system Anatomy 0.000 description 2
- 210000002966 serum Anatomy 0.000 description 2
- 239000003381 stabilizer Substances 0.000 description 2
- 230000001018 virulence Effects 0.000 description 2
- SVTBMSDMJJWYQN-UHFFFAOYSA-N 2-methylpentane-2,4-diol Chemical compound CC(O)CC(C)(C)O SVTBMSDMJJWYQN-UHFFFAOYSA-N 0.000 description 1
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 1
- 208000031504 Asymptomatic Infections Diseases 0.000 description 1
- 101100481176 Bacillus subtilis (strain 168) thiE gene Proteins 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 description 1
- 241000283707 Capra Species 0.000 description 1
- 101150023426 Ccin gene Proteins 0.000 description 1
- 241000282693 Cercopithecidae Species 0.000 description 1
- 229920000742 Cotton Polymers 0.000 description 1
- 101100494344 Desulfobacterium autotrophicum (strain ATCC 43914 / DSM 3382 / HRM2) bzaF gene Proteins 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
- 239000004594 Masterbatch (MB) Substances 0.000 description 1
- 240000008881 Oenanthe javanica Species 0.000 description 1
- 229930182555 Penicillin Natural products 0.000 description 1
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 description 1
- 241000709664 Picornaviridae Species 0.000 description 1
- 206010035148 Plague Diseases 0.000 description 1
- 206010035664 Pneumonia Diseases 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 241000607479 Yersinia pestis Species 0.000 description 1
- 240000008042 Zea mays Species 0.000 description 1
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 1
- 239000000443 aerosol Substances 0.000 description 1
- -1 amine lactose glutamate Chemical class 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 235000005822 corn Nutrition 0.000 description 1
- 230000001054 cortical effect Effects 0.000 description 1
- 230000034994 death Effects 0.000 description 1
- 239000008121 dextrose Substances 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 210000002919 epithelial cell Anatomy 0.000 description 1
- 230000001747 exhibiting effect Effects 0.000 description 1
- 210000003754 fetus Anatomy 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 230000002163 immunogen Effects 0.000 description 1
- 230000016784 immunoglobulin production Effects 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 201000009020 malignant peripheral nerve sheath tumor Diseases 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 230000003387 muscular Effects 0.000 description 1
- 230000017074 necrotic cell death Effects 0.000 description 1
- 208000029974 neurofibrosarcoma Diseases 0.000 description 1
- 238000006386 neutralization reaction Methods 0.000 description 1
- 230000007918 pathogenicity Effects 0.000 description 1
- NRNCYVBFPDDJNE-UHFFFAOYSA-N pemoline Chemical group O1C(N)=NC(=O)C1C1=CC=CC=C1 NRNCYVBFPDDJNE-UHFFFAOYSA-N 0.000 description 1
- 229940049954 penicillin Drugs 0.000 description 1
- 210000003800 pharynx Anatomy 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 208000023504 respiratory system disease Diseases 0.000 description 1
- 238000012552 review Methods 0.000 description 1
- 208000026425 severe pneumonia Diseases 0.000 description 1
- 239000002356 single layer Substances 0.000 description 1
- 206010041232 sneezing Diseases 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 210000001550 testis Anatomy 0.000 description 1
- 101150029215 thiC gene Proteins 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 210000003437 trachea Anatomy 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/125—Picornaviridae, e.g. calicivirus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/16011—Caliciviridae
- C12N2770/16034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/819—Viral vaccine for feline species, e.g. cats
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/525,689 US3944469A (en) | 1974-11-21 | 1974-11-21 | Feline calicivirus vaccine and production thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1055844A true CA1055844A (en) | 1979-06-05 |
Family
ID=24094242
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA240,138A Expired CA1055844A (en) | 1974-11-21 | 1975-11-20 | Feline calicivirus vaccine and production thereof |
Country Status (17)
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4287178A (en) * | 1974-03-25 | 1981-09-01 | Pitman-Moore, Inc. | Feline rhinotracheitis vaccine and production and use thereof |
| ES486442A0 (es) * | 1978-11-30 | 1980-12-16 | Wellcome Found | Un metodo de preparar una vacuna que contiene una cepa ate- nuada de virus de peritonitis infecciosa felina. |
| US4303644A (en) * | 1979-10-16 | 1981-12-01 | Norden Laboratories, Inc. | Feline infectious peritonitis virus vaccines |
| US4303645A (en) * | 1980-04-18 | 1981-12-01 | Cornell Research Foundation, Inc. | Modified living canine parvovirus vaccine |
| US4537769A (en) * | 1982-04-06 | 1985-08-27 | American Cyanamid Company | Stabilization of influenza virus vaccine |
| US4522810A (en) * | 1982-12-09 | 1985-06-11 | The Regents Of The University Of California | Feline calicivirus vaccine |
| US5374424A (en) * | 1986-10-03 | 1994-12-20 | Miles Inc. | Multivalent felv-infected feline vaccine |
| AU661106B2 (en) * | 1992-02-28 | 1995-07-13 | Juridical Foundation The Chemo-Sero-Therapeutic Research Institute | Anti-feline calicivirus recombinant antibody and gene fragment encoding the same |
| AU5329300A (en) | 1999-06-10 | 2001-01-02 | Michigan State University | Feline calicivirus isolated from cat urine and vaccines thereof |
| EP1606391B1 (en) * | 2003-03-14 | 2011-01-19 | Regents of the University of California | Virulent systemic feline calicivirus |
| US7309495B2 (en) * | 2003-03-14 | 2007-12-18 | The Regents Of The University Of California | Hemorrhagic feline calicivirus |
| US7306807B2 (en) * | 2004-09-13 | 2007-12-11 | Wyeth | Hemorrhagic feline calicivirus, calicivirus vaccine and method for preventing calicivirus infection or disease |
| CN101563096A (zh) * | 2005-07-28 | 2009-10-21 | 辉瑞产品公司 | 疫苗施用方法、新猫杯状病毒、及抗猫细小病毒和猫疱疹病毒的动物免疫方法 |
| CA2681183A1 (en) * | 2007-05-30 | 2008-12-11 | Wyeth | Raccoon poxvirus expressing genes of feline antigens |
| WO2017106079A1 (en) | 2015-12-14 | 2017-06-22 | Boehringer Ingelheim Vetmedica, Inc. | Hybrid core feline vaccines |
| CN114874997B (zh) * | 2022-05-26 | 2023-05-23 | 中国农业科学院哈尔滨兽医研究所（中国动物卫生与流行病学中心哈尔滨分中心） | 猫杯状病毒 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1177635A (en) * | 1966-02-18 | 1970-01-14 | Wellcome Found | Cell Stains. |
-
1974
- 1974-11-21 US US05/525,689 patent/US3944469A/en not_active Expired - Lifetime
-
1975
- 1975-10-30 GB GB45026/75A patent/GB1522006A/en not_active Expired
- 1975-11-03 NO NO753676A patent/NO753676L/no unknown
- 1975-11-14 SE SE7512828A patent/SE7512828L/xx not_active Application Discontinuation
- 1975-11-17 CH CH1487975A patent/CH622702A5/de not_active IP Right Cessation
- 1975-11-17 DK DK516975AA patent/DK141339B/da unknown
- 1975-11-19 JP JP50138275A patent/JPS5173118A/ja active Pending
- 1975-11-19 AU AU86755/75A patent/AU508944B2/en not_active Expired
- 1975-11-20 FR FR7535498A patent/FR2291766A1/fr active Granted
- 1975-11-20 CA CA240,138A patent/CA1055844A/en not_active Expired
- 1975-11-20 DE DE19752552137 patent/DE2552137A1/de not_active Withdrawn
- 1975-11-20 BE BE162051A patent/BE835784A/xx unknown
- 1975-11-20 ZA ZA757294A patent/ZA757294B/xx unknown
- 1975-11-20 AT AT884975A patent/AT340584B/de active
- 1975-11-20 FI FI753274A patent/FI53593C/fi not_active IP Right Cessation
- 1975-11-21 NL NL7513644A patent/NL7513644A/xx not_active Application Discontinuation
- 1975-11-21 ES ES442892A patent/ES442892A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| AU508944B2 (en) | 1980-04-17 |
| ES442892A1 (es) | 1977-08-16 |
| BE835784A (fr) | 1976-05-20 |
| FI53593B (US20100154141A1-20100624-C00001.png) | 1978-02-28 |
| NO753676L (US20100154141A1-20100624-C00001.png) | 1976-05-24 |
| FR2291766B1 (US20100154141A1-20100624-C00001.png) | 1978-07-28 |
| DE2552137A1 (de) | 1976-05-26 |
| ZA757294B (en) | 1977-06-29 |
| AT340584B (de) | 1977-12-27 |
| DK516975A (US20100154141A1-20100624-C00001.png) | 1976-05-22 |
| FI753274A (US20100154141A1-20100624-C00001.png) | 1976-05-22 |
| FR2291766A1 (fr) | 1976-06-18 |
| NL7513644A (nl) | 1976-05-25 |
| AU8675575A (en) | 1977-05-26 |
| DK141339C (US20100154141A1-20100624-C00001.png) | 1980-08-25 |
| SE7512828L (sv) | 1976-05-24 |
| GB1522006A (en) | 1978-08-23 |
| JPS5173118A (US20100154141A1-20100624-C00001.png) | 1976-06-24 |
| CH622702A5 (US20100154141A1-20100624-C00001.png) | 1981-04-30 |
| FI53593C (fi) | 1978-06-12 |
| DK141339B (da) | 1980-02-25 |
| ATA884975A (de) | 1977-04-15 |
| US3944469A (en) | 1976-03-16 |
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