CA1054601A - Process for the production of 1-amino-3-phenyl indoles derivatives having antimicrobial and antidepressant properties - Google Patents

Process for the production of 1-amino-3-phenyl indoles derivatives having antimicrobial and antidepressant properties

Info

Publication number
CA1054601A
CA1054601A CA223211A CA223211A CA1054601A CA 1054601 A CA1054601 A CA 1054601A CA 223211 A CA223211 A CA 223211A CA 223211 A CA223211 A CA 223211A CA 1054601 A CA1054601 A CA 1054601A
Authority
CA
Canada
Prior art keywords
amino
alkyl
indole
phenyl
alkanoyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA223211A
Other languages
English (en)
French (fr)
Inventor
Franz Schatz
Christian Stammbach
Theodor Wagner-Jauregg
Kurt Thiele
Johanna Fischer
Ulrich Jahn
Ludwig Zirngibl
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siegfried AG
Original Assignee
Siegfried AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Siegfried AG filed Critical Siegfried AG
Application granted granted Critical
Publication of CA1054601A publication Critical patent/CA1054601A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/16—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • C07D249/18—Benzotriazoles

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pain & Pain Management (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA223211A 1974-03-29 1975-03-21 Process for the production of 1-amino-3-phenyl indoles derivatives having antimicrobial and antidepressant properties Expired CA1054601A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH439974A CH603581A5 (ja) 1974-03-29 1974-03-29

Publications (1)

Publication Number Publication Date
CA1054601A true CA1054601A (en) 1979-05-15

Family

ID=4275407

Family Applications (1)

Application Number Title Priority Date Filing Date
CA223211A Expired CA1054601A (en) 1974-03-29 1975-03-21 Process for the production of 1-amino-3-phenyl indoles derivatives having antimicrobial and antidepressant properties

Country Status (15)

Country Link
JP (1) JPS6036423B2 (ja)
AT (1) AT346840B (ja)
BE (1) BE827399A (ja)
CA (1) CA1054601A (ja)
CH (1) CH603581A5 (ja)
DE (1) DE2512702C2 (ja)
DK (1) DK133175A (ja)
ES (1) ES435944A1 (ja)
FR (1) FR2265365B1 (ja)
GB (1) GB1502821A (ja)
IE (1) IE41223B1 (ja)
LU (1) LU72170A1 (ja)
NL (1) NL7502722A (ja)
SE (1) SE409113B (ja)
ZA (1) ZA752001B (ja)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1113879B (it) * 1979-03-15 1986-01-27 Farmatis Spa Derivato isoindolinico,processo per la sua preparazione e composizioni terapeutiche che lo comprendono come principio attivo
DE3022097A1 (de) * 1980-06-12 1981-12-24 Siegfried AG, Zofingen 1-amino-3-phenyl-indole und deren verwendung
EP0287982B1 (en) * 1987-04-24 1994-12-07 Hoechst-Roussel Pharmaceuticals Incorporated N-(Pyridinyl)-1H-indol-1-amines, a process for their preparation and their use as medicaments

Also Published As

Publication number Publication date
SE409113B (sv) 1979-07-30
CH603581A5 (ja) 1978-08-31
JPS6036423B2 (ja) 1985-08-20
FR2265365A1 (ja) 1975-10-24
NL7502722A (nl) 1975-10-01
AT346840B (de) 1978-11-27
JPS50130758A (ja) 1975-10-16
ES435944A1 (es) 1976-12-16
ATA226975A (de) 1978-04-15
SE7503533L (ja) 1975-09-30
FR2265365B1 (ja) 1978-07-28
ZA752001B (en) 1976-02-25
IE41223B1 (en) 1979-11-21
GB1502821A (en) 1978-03-01
DE2512702C2 (de) 1982-09-23
BE827399A (fr) 1975-09-29
IE41223L (en) 1975-09-29
LU72170A1 (ja) 1976-02-04
DK133175A (ja) 1975-09-30
DE2512702A1 (de) 1975-10-09

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