CA1046513A - Antibiotic derivatives - Google Patents

Antibiotic derivatives

Info

Publication number
CA1046513A
CA1046513A CA193,107A CA193107A CA1046513A CA 1046513 A CA1046513 A CA 1046513A CA 193107 A CA193107 A CA 193107A CA 1046513 A CA1046513 A CA 1046513A
Authority
CA
Canada
Prior art keywords
amino
alpha
compound
water
hydroxyvaleryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA193,107A
Other languages
English (en)
French (fr)
Other versions
CA193107S (en
Inventor
Takayuki Naito
Susumu Nakagawa
Yoshio Abe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US335210A external-priority patent/US3886139A/en
Priority claimed from US335211A external-priority patent/US3904597A/en
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of CA1046513A publication Critical patent/CA1046513A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/22Cyclohexane rings, substituted by nitrogen atoms
    • C07H15/222Cyclohexane rings substituted by at least two nitrogen atoms
    • C07H15/226Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
    • C07H15/234Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids
    • C07C271/08Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
CA193,107A 1973-02-23 1974-02-21 Antibiotic derivatives Expired CA1046513A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US335210A US3886139A (en) 1973-02-23 1973-02-23 Derivatives of kanamycin
US335211A US3904597A (en) 1973-02-23 1973-02-23 Antibiotic derivatives

Publications (1)

Publication Number Publication Date
CA1046513A true CA1046513A (en) 1979-01-16

Family

ID=26989599

Family Applications (1)

Application Number Title Priority Date Filing Date
CA193,107A Expired CA1046513A (en) 1973-02-23 1974-02-21 Antibiotic derivatives

Country Status (9)

Country Link
JP (1) JPS553360B2 (de)
CA (1) CA1046513A (de)
CH (1) CH599243A5 (de)
DE (1) DE2408666C3 (de)
DK (1) DK140259B (de)
FR (1) FR2218879B2 (de)
GB (1) GB1467401A (de)
NL (1) NL7402456A (de)
SE (1) SE417972B (de)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9938217B2 (en) 2016-07-01 2018-04-10 Res Usa, Llc Fluidized bed membrane reactor
US9981896B2 (en) 2016-07-01 2018-05-29 Res Usa, Llc Conversion of methane to dimethyl ether
US10189763B2 (en) 2016-07-01 2019-01-29 Res Usa, Llc Reduction of greenhouse gas emission

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5512038B2 (de) * 1973-05-15 1980-03-29
DE2860513D1 (en) * 1977-06-24 1981-04-09 Scherico Ltd Process for preparing aminoglycoside derivatives, novel derivatives obtained and pharmaceutical compositions containing such derivatives

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR205516A1 (es) * 1972-03-08 1976-05-14 Bristol Myers Co Proceso para la preparacion de derivados de tobramicina

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9938217B2 (en) 2016-07-01 2018-04-10 Res Usa, Llc Fluidized bed membrane reactor
US9981896B2 (en) 2016-07-01 2018-05-29 Res Usa, Llc Conversion of methane to dimethyl ether
US10189763B2 (en) 2016-07-01 2019-01-29 Res Usa, Llc Reduction of greenhouse gas emission

Also Published As

Publication number Publication date
FR2218879A2 (de) 1974-09-20
JPS553360B2 (de) 1980-01-24
DE2408666C3 (de) 1978-10-19
SE417972B (sv) 1981-04-27
DE2408666A1 (de) 1974-09-12
AU6587574A (en) 1975-08-21
FR2218879B2 (de) 1978-05-26
NL7402456A (de) 1974-08-27
DK140259B (da) 1979-07-16
JPS504043A (de) 1975-01-16
GB1467401A (en) 1977-03-16
DE2408666B2 (de) 1978-02-16
CH599243A5 (de) 1978-05-31
DK140259C (de) 1979-12-10

Similar Documents

Publication Publication Date Title
US3781268A (en) Antibiotic derivatives of kanamycin
US3897412A (en) Paromomycin antibiotic derivatives
US4055715A (en) Method of producing 1-N-[L-(-)-α-hydroxy-γ-aminobutyryl]XK-62-2
US4117221A (en) Aminoacyl derivatives of aminoglycoside antibiotics
US3808198A (en) Lividomycin b derivatives
US3860574A (en) Derivatives of neomycin b and neomycin c
US4170642A (en) Derivatives of kanamycin A
US3872079A (en) Semisynthetic derivatives of tobramycin
US4066753A (en) Neomycin and paromomycin derivatives
US3896106A (en) Antibiotic derivatives
CA1081692A (en) Method for production of kanamycin c and its derivatives
CA1046513A (en) Antibiotic derivatives
DK149775B (da) Analogifremgangsmaade til fremstilling af 6'-n-methylkanamycin a- og b-derivater
US3886139A (en) Derivatives of kanamycin
US4076931A (en) Derivatives of an antibiotic XK-62-2 and the process for the production thereof
US3939143A (en) 1-N-isoserylkanamycins and the production thereof
DE2458921C3 (de) N-(2-Hydroxy-4-aminobutyryl)-Derivate des Antibiotikums XK-62-2, ihre Salze, Verfahren zu ihrer Herstellung und Arzneimittel
US3796698A (en) Antibiotic derivatives of gentamicin c2
US4008362A (en) 1-N-((S)-α-substituted-ω-aminoacyl)-neamine or -ribostamycin and the production thereof
CA1088080A (en) Fortimicin derivatives and method for production thereof
US4181797A (en) 1-N-(ω-amino-α-hydroxyalkanoyl) derivatives of 4'-deoxy-6'-N-methylkanamycin A
US3904597A (en) Antibiotic derivatives
US4362866A (en) Aprosamine derivatives
US4132846A (en) 1-N-(α-Hydroxy-β-aminopropionyl) XK-62-2 and method of production thereof
US4252972A (en) Fortimicin B-1,2:4,5-bis-carbamates