CA1032931A - Modes de synthese de derives des acides penam-3-carboxylique et cephem-4 carboxylique - Google Patents

Modes de synthese de derives des acides penam-3-carboxylique et cephem-4 carboxylique

Info

Publication number
CA1032931A
CA1032931A CA166,650A CA166650A CA1032931A CA 1032931 A CA1032931 A CA 1032931A CA 166650 A CA166650 A CA 166650A CA 1032931 A CA1032931 A CA 1032931A
Authority
CA
Canada
Prior art keywords
carboxylic acid
penam
cephem
derivatives
manufacture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA166,650A
Other languages
English (en)
Other versions
CA166650S (en
Inventor
Bruno Fechtig
Hans Bickel
Karoly Kocsis
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Application granted granted Critical
Publication of CA1032931A publication Critical patent/CA1032931A/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C265/00—Derivatives of isocyanic acid
    • C07C265/16—Derivatives of isocyanic acid having isocyanate groups acylated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
CA166,650A 1972-03-29 1973-03-21 Modes de synthese de derives des acides penam-3-carboxylique et cephem-4 carboxylique Expired CA1032931A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH473272A CH570407A5 (fr) 1972-03-29 1972-03-29

Publications (1)

Publication Number Publication Date
CA1032931A true CA1032931A (fr) 1978-06-13

Family

ID=4281543

Family Applications (1)

Application Number Title Priority Date Filing Date
CA166,650A Expired CA1032931A (fr) 1972-03-29 1973-03-21 Modes de synthese de derives des acides penam-3-carboxylique et cephem-4 carboxylique

Country Status (17)

Country Link
US (1) US3954802A (fr)
JP (1) JPS495990A (fr)
AR (1) AR205610A1 (fr)
AT (2) AT326825B (fr)
BE (1) BE797444A (fr)
CA (1) CA1032931A (fr)
CH (1) CH570407A5 (fr)
DD (1) DD105618A5 (fr)
DE (1) DE2313667A1 (fr)
FR (1) FR2182905B1 (fr)
GB (1) GB1429539A (fr)
HU (1) HU168373B (fr)
IE (1) IE37432B1 (fr)
IL (1) IL41824A0 (fr)
NL (1) NL7304339A (fr)
PL (1) PL91815B1 (fr)
ZA (1) ZA732010B (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2233067A1 (en) * 1973-06-12 1975-01-10 Beecham Group Ltd N-(thio)acyl carbamoyl-glycylamino-cephalosporin ic acids - as antibiotics esp. active against pseudomonas and gram neg. organisms producing cephalosporinase
GB1479711A (en) * 1973-06-12 1977-07-13 Beecham Group Ltd Acylureido cephalosporins
IL47168A (en) * 1974-05-09 1979-07-25 Toyama Chemical Co Ltd Mono or dioxo piperazino(thio)carbonylamino derivatives ofpenicillins and cephalosporins and process for producing the same
JPS51115491A (en) * 1975-04-03 1976-10-12 Sumitomo Chem Co Ltd Method for preparing 77* *44hydroxyy1*5 naphthyridinee33carboxyamino ** phenylacetamido*cephalosporins
US4028354A (en) * 1976-03-08 1977-06-07 E. R. Squibb & Sons, Inc. Alkenyl and alkinylureido cephalosporins
US4041162A (en) * 1976-03-11 1977-08-09 Smithkline Corporation 7-Acyl-3-(sulfoalkyl substituted oxadiazolylthiomethyl) cephalosporins
US4099001A (en) * 1977-03-15 1978-07-04 E. R. Squibb & Sons, Inc. [[[Imidazolidinyl amino]carbonyl]amino]acetyl cephalosporin derivatives
JPS61157090A (ja) * 1984-12-28 1986-07-16 Res Dev Corp Of Japan 運動軌跡表示方法
JPS6357034A (ja) * 1986-08-27 1988-03-11 服部　友一 光学式自動動作分析装置

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE32700B1 (en) * 1968-02-03 1973-10-31 Beecham Group Ltd Penicillins
US3481922A (en) * 1968-06-13 1969-12-02 Bristol Myers Co 6-(alpha - 3 - acylthioureidophenylacetamido)-and 6 - (alpha-3-acylthioureidothienylacetamido)-penicillanic acids
US3483188A (en) * 1968-06-13 1969-12-09 Bristol Myers Co 6-(alpha - 3 - allophanamidophenylacetamido) and 6 - (alpha - 3 - allophanamidothienylacetamido)-penicillanic acids
US3687949A (en) * 1969-01-21 1972-08-29 Bristol Myers Co Synthetic cephalosporins
US3579501A (en) * 1969-08-22 1971-05-18 Bristol Myers Co 6-(alpha-(3 - guanyl - 1 - ureido)phenyl- or thienyl-acetamido)penicillanic acids

Also Published As

Publication number Publication date
NL7304339A (fr) 1973-10-02
FR2182905B1 (fr) 1976-08-13
JPS495990A (fr) 1974-01-19
US3954802A (en) 1976-05-04
AT326825B (de) 1975-12-29
PL91815B1 (fr) 1977-03-31
AR205610A1 (es) 1976-05-21
FR2182905A1 (fr) 1973-12-14
IE37432L (en) 1973-09-29
ATA271373A (de) 1975-01-15
HU168373B (fr) 1976-04-28
AT325766B (de) 1975-11-10
DE2313667A1 (de) 1973-10-11
IL41824A0 (en) 1973-05-31
GB1429539A (en) 1976-03-24
DD105618A5 (fr) 1974-05-05
BE797444A (fr) 1973-09-28
ZA732010B (en) 1974-01-30
CH570407A5 (fr) 1975-12-15
IE37432B1 (en) 1977-07-20

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