CA1030522A - D-homo-20-keto-pregnanes - Google Patents

D-homo-20-keto-pregnanes

Info

Publication number
CA1030522A
CA1030522A CA215,097A CA215097A CA1030522A CA 1030522 A CA1030522 A CA 1030522A CA 215097 A CA215097 A CA 215097A CA 1030522 A CA1030522 A CA 1030522A
Authority
CA
Canada
Prior art keywords
pregnanes
keto
homo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA215,097A
Other languages
English (en)
French (fr)
Other versions
CA215097S (en
Inventor
Klaus Kieslich
Karl Petzoldt
Rudolf Wiechert
Reinhard Horowski
Gert Paschelke
Dieter Palenschat
Ulrich Kerb
Helmut Wachtel
Wolfgang Kehr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2360443A external-priority patent/DE2360443A1/de
Priority claimed from DE19742445161 external-priority patent/DE2445161A1/de
Application filed by Schering AG filed Critical Schering AG
Application granted granted Critical
Publication of CA1030522A publication Critical patent/CA1030522A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J63/00Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008Expansion of ring D by one atom, e.g. D homo steroids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00Preparation of steroids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Steroid Compounds (AREA)
CA215,097A 1973-11-30 1974-12-02 D-homo-20-keto-pregnanes Expired CA1030522A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2360443A DE2360443A1 (de) 1973-11-30 1973-11-30 D-homo-20-ketopregnane
DE19742445161 DE2445161A1 (de) 1974-09-19 1974-09-19 D-homo-20-ketopregnane ii

Publications (1)

Publication Number Publication Date
CA1030522A true CA1030522A (en) 1978-05-02

Family

ID=25766200

Family Applications (1)

Application Number Title Priority Date Filing Date
CA215,097A Expired CA1030522A (en) 1973-11-30 1974-12-02 D-homo-20-keto-pregnanes

Country Status (14)

Country Link
US (1) US4045574A (forum.php)
JP (1) JPS5084561A (forum.php)
AT (1) AT347611B (forum.php)
CA (1) CA1030522A (forum.php)
CH (1) CH618183A5 (forum.php)
DD (1) DD115659A5 (forum.php)
DK (1) DK134348C (forum.php)
ES (1) ES432106A1 (forum.php)
FR (1) FR2253512B1 (forum.php)
GB (1) GB1494097A (forum.php)
IE (1) IE40423B1 (forum.php)
IL (1) IL46153A (forum.php)
NL (1) NL7415577A (forum.php)
SE (1) SE408426B (forum.php)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4879316A (en) * 1987-02-26 1989-11-07 The University Of Tennessee Research Corporation Interpenetrating polymer network ion exchange membranes and method for preparing same
US6787530B1 (en) 1996-08-23 2004-09-07 Monash University Use of pregnane-diones as analgesic agents
ES2271636T3 (es) * 2002-08-16 2007-04-16 PHARMACIA & UPJOHN COMPANY LLC Intermediarios de 5 androsten-3-ol esteroides y procedimientos para su preparacion.
US20070066579A1 (en) * 2002-08-16 2007-03-22 White Michael J 5-androsten-3beta-ol steroid intermediates and processs for their preparation
WO2014169831A1 (en) 2013-04-17 2014-10-23 Sage Therapeutics, Inc. 19-nor c3,3-disubstituted c21-c-bound heteroaryl steroids and methods of use thereof
ES2998982T3 (en) 2013-04-17 2025-02-24 Sage Therapeutics Inc 19-nor neuroactive steroids for inducing sedation
JP6470258B2 (ja) 2013-04-17 2019-02-13 セージ セラピューティクス, インコーポレイテッド 19−ノルc3,3−ジ置換c21−n−ピラゾリルステロイドおよびその使用方法
WO2014169836A1 (en) 2013-04-17 2014-10-23 Sage Therapeutics, Inc. 19-nor neuroactive steroids and methods of use thereof
HUE053900T2 (hu) 2013-07-19 2021-07-28 Sage Therapeutics Inc Neuroaktív szteroidok, kompozíciók, és azok alkalmazásai
CN105579043B (zh) 2013-08-23 2021-09-14 萨奇治疗股份有限公司 神经活性类固醇、组合物和其用途
WO2015195962A1 (en) 2014-06-18 2015-12-23 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
US10577390B2 (en) 2014-10-16 2020-03-03 Sage Therapeutics, Inc. Compositions and methods for treating CNS disorders
SI3206493T1 (sl) 2014-10-16 2020-10-30 Sage Therapeutics, Inc. Sestavki in metode za zdravljenje CNS motenj
LT3224269T (lt) 2014-11-27 2020-07-10 Sage Therapeutics, Inc. Kompozicijos ir būdai, skirti cns sutrikimams gydyti
RS61530B1 (sr) 2015-01-26 2021-04-29 Sage Therapeutics Inc Kompozicije i postupci za lečenje poremećaja cns
ES2935476T3 (es) 2015-02-20 2023-03-07 Sage Therapeutics Inc Esteroides neuroactivos, composiciones y usos de los mismos
DK3481845T3 (da) 2016-07-11 2023-11-27 Sage Therapeutics Inc C17, c20 og c21 substituerede neuroaktive steroider og deres anvendelsesmetoder
NZ790186A (en) 2016-07-11 2025-08-29 Sage Therapeutics Inc C7, C12, and C16 substituted neuroactive steroids and their methods of use
EP3728285A1 (en) * 2017-12-22 2020-10-28 Sage Therapeutics, Inc. Compositions and methods for treating cns disorders
IL312610A (en) 2018-12-05 2024-07-01 Sage Therapeutics Inc Neuroactive steroids and methods of using them
BR112021013393A2 (pt) 2019-01-08 2021-09-14 Chengdu Kanghong Pharmaceutical Co, Ltd. Composto de esteroide e uso do mesmo e método de preparação para o mesmo
EP3976628A1 (en) 2019-05-31 2022-04-06 Sage Therapeutics, Inc. Neuroactive steroids and compositions thereof
EP3990467A1 (en) * 2019-06-27 2022-05-04 Sage Therapeutics, Inc. Compositions and methods for treating cns disorders
JP7670632B2 (ja) * 2019-06-27 2025-04-30 セージ セラピューティクス, インコーポレイテッド Cns障害を治療するための組成物及び方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2860158A (en) * 1954-10-18 1958-11-11 Sterling Drug Inc Compounds of the perhydrochrysene series and preparation thereof
US3686223A (en) * 1968-12-26 1972-08-22 Sterling Drug Inc D-homoestratrienes
US3833621A (en) * 1972-03-20 1974-09-03 Richardson Merrell Inc 3-keto-7(alpha,beta)-loweralkyl-delta5 steroids and process for preparing same

Also Published As

Publication number Publication date
JPS5084561A (forum.php) 1975-07-08
DK134348C (da) 1977-03-21
SE7414960L (forum.php) 1975-06-02
FR2253512A1 (forum.php) 1975-07-04
AT347611B (de) 1979-01-10
DK134348B (da) 1976-10-25
FR2253512B1 (forum.php) 1978-02-03
IE40423B1 (en) 1979-05-23
ATA950774A (de) 1978-05-15
GB1494097A (en) 1977-12-07
SE408426B (sv) 1979-06-11
IL46153A0 (en) 1975-02-10
ES432106A1 (es) 1976-11-01
IE40423L (en) 1975-05-30
AU7586774A (en) 1976-06-03
US4045574A (en) 1977-08-30
DK604174A (forum.php) 1975-07-28
CH618183A5 (forum.php) 1980-07-15
NL7415577A (nl) 1975-06-03
DD115659A5 (forum.php) 1975-10-12
IL46153A (en) 1979-01-31

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