CA1025442A - Procede de preparation d'un nouveau sel d'erythromycine - Google Patents

Procede de preparation d'un nouveau sel d'erythromycine

Info

Publication number
CA1025442A
CA1025442A CA230,434A CA230434A CA1025442A CA 1025442 A CA1025442 A CA 1025442A CA 230434 A CA230434 A CA 230434A CA 1025442 A CA1025442 A CA 1025442A
Authority
CA
Canada
Prior art keywords
érythromycine
pyroglutamate
eau
que
procédé
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA230,434A
Other languages
English (en)
Inventor
Jean A. Grandadam
Lucien Penasse
Pierre Barthelemy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Application granted granted Critical
Publication of CA1025442A publication Critical patent/CA1025442A/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D207/28—2-Pyrrolidone-5- carboxylic acids; Functional derivatives thereof, e.g. esters, nitriles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

PRECIS DE LA DIVULGATION:

L'invention a pour objet un procédé de préparation du pyroglutamate d'érythromycine qui consiste à faire réagir de l'acide pyroglutamique sur de l'érythromycine base. Le pyroglutamate d'érythromycine obtenu est doué d'une activité
bactériostatique et bactéricide.
CA230,434A 1974-07-02 1975-06-30 Procede de preparation d'un nouveau sel d'erythromycine Expired CA1025442A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7423013A FR2302084A1 (fr) 1974-07-02 1974-07-02 Nouveau sel d'erythromycine, son procede de preparation et son application a titre de medicament

Publications (1)

Publication Number Publication Date
CA1025442A true CA1025442A (fr) 1978-01-31

Family

ID=9140790

Family Applications (1)

Application Number Title Priority Date Filing Date
CA230,434A Expired CA1025442A (fr) 1974-07-02 1975-06-30 Procede de preparation d'un nouveau sel d'erythromycine

Country Status (11)

Country Link
JP (1) JPS5129217A (fr)
BE (1) BE830842A (fr)
CA (1) CA1025442A (fr)
CH (1) CH599152A5 (fr)
DE (1) DE2529538A1 (fr)
DK (1) DK299375A (fr)
FR (1) FR2302084A1 (fr)
GB (1) GB1485210A (fr)
IE (1) IE41628B1 (fr)
LU (1) LU72866A1 (fr)
NL (1) NL7507863A (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5633353A (en) * 1979-08-20 1981-04-03 Toray Ind Inc Reeling-out method for thread
DK0804088T3 (da) * 1994-06-29 2000-11-20 Meiji Seika Kaisha Stabiliseret sammensætning, der omfatter solisinsulfat

Also Published As

Publication number Publication date
JPS5129217A (en) 1976-03-12
IE41628B1 (en) 1980-02-13
BE830842A (fr) 1975-12-30
DK299375A (da) 1976-01-03
CH599152A5 (fr) 1978-05-12
NL7507863A (nl) 1976-01-06
IE41628L (en) 1976-01-02
FR2302084A1 (fr) 1976-09-24
GB1485210A (en) 1977-09-08
DE2529538A1 (de) 1976-01-22
FR2302084B1 (fr) 1979-05-18
LU72866A1 (fr) 1976-04-13

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