CA1016538A - 6-(.alpha.-(.omega.-GUANIDINOALKANOYLAMIDO)ACYLAMIDO) PENICILLANICS ACIDS - Google Patents

6-(.alpha.-(.omega.-GUANIDINOALKANOYLAMIDO)ACYLAMIDO) PENICILLANICS ACIDS

Info

Publication number
CA1016538A
CA1016538A CA160,794A CA160794A CA1016538A CA 1016538 A CA1016538 A CA 1016538A CA 160794 A CA160794 A CA 160794A CA 1016538 A CA1016538 A CA 1016538A
Authority
CA
Canada
Prior art keywords
penicillanics
guanidinoalkanoylamido
acylamido
omega
alpha
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA160,794A
Other languages
English (en)
Other versions
CA160794S (en
Inventor
Ernest S. Hamanaka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Application granted granted Critical
Publication of CA1016538A publication Critical patent/CA1016538A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/21—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a nitrogen atom directly attached in position 6 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D499/44—Compounds with an amino radical acylated by carboxylic acids, attached in position 6
    • C07D499/48—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical
    • C07D499/58—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical
    • C07D499/64—Compounds with an amino radical acylated by carboxylic acids, attached in position 6 with a carbon chain, substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, attached to the carboxamido radical substituted in alpha-position to the carboxamido radical by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA160,794A 1972-02-22 1973-01-09 6-(.alpha.-(.omega.-GUANIDINOALKANOYLAMIDO)ACYLAMIDO) PENICILLANICS ACIDS Expired CA1016538A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US228344A US3870709A (en) 1972-02-22 1972-02-22 6-(alpha-(ome ga-guanidinoalkanoylamido)acylamido)penicillanic acids

Publications (1)

Publication Number Publication Date
CA1016538A true CA1016538A (en) 1977-08-30

Family

ID=22856799

Family Applications (1)

Application Number Title Priority Date Filing Date
CA160,794A Expired CA1016538A (en) 1972-02-22 1973-01-09 6-(.alpha.-(.omega.-GUANIDINOALKANOYLAMIDO)ACYLAMIDO) PENICILLANICS ACIDS

Country Status (11)

Country Link
US (1) US3870709A (xx)
JP (1) JPS4896597A (xx)
AR (1) AR196000A1 (xx)
AU (1) AU473210B2 (xx)
BE (1) BE794886A (xx)
CA (1) CA1016538A (xx)
CH (1) CH561218A5 (xx)
DE (1) DE2304591A1 (xx)
ES (1) ES411065A1 (xx)
FR (1) FR2181713B1 (xx)
GB (1) GB1379502A (xx)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9827217B2 (en) 2015-08-25 2017-11-28 Rgenix, Inc. Pharmaceutically acceptable salts of B-guanidinopropionic acid with improved properties and uses thereof
US9884813B1 (en) 2017-03-01 2018-02-06 Rgenix, Inc. Pharmaceutically acceptable salts of B-guanidinopropionic acid with improved properties and uses thereof
US12011427B2 (en) 2019-12-11 2024-06-18 Inspirna, Inc. Methods of treating cancer

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3951952A (en) * 1972-08-02 1976-04-20 Pfizer Inc. Broad spectrum antibiotics
US4025504A (en) * 1973-12-14 1977-05-24 Pfizer Inc. Broad Spectrum antibiotics
GB1462421A (en) * 1973-12-14 1977-01-26 Pfizer 6-a-amidino-and -'midoylaminoalkanoylamino aracylamino-penicillanic acids and their preparation
US4025506A (en) * 1973-12-14 1977-05-24 Pfizer Inc. Broad spectrum antibiotics
IL47168A (en) * 1974-05-09 1979-07-25 Toyama Chemical Co Ltd Mono or dioxo piperazino(thio)carbonylamino derivatives ofpenicillins and cephalosporins and process for producing the same
GB1503918A (en) * 1974-06-18 1978-03-15 Beecham Group Ltd Penicillins
FR2288521A1 (fr) * 1974-10-25 1976-05-21 Merck Patent Gmbh Nouvelles penicillines et procede pour leur preparation
DE2458973A1 (de) * 1974-12-13 1976-06-16 Hoechst Ag Acylaminopenicillansaeuren und verfahren zu ihrer herstellung
US4073780A (en) * 1976-06-03 1978-02-14 Pfizer Inc. 4-Pyridylformimidoylglycyl-D-phenylglycine
US4038271A (en) * 1976-11-08 1977-07-26 E. R. Squibb & Sons, Inc. [[[(2,4-Dioxo-1-imidazolidinyl)amino]-carbonyl]amino]acetylpenicillin derivatives
US8350077B2 (en) * 2008-12-24 2013-01-08 Vertex Closed Joint Stock Company Amides of creatine, method of their preparation, and remedy possessing a neuroprotective activity
RU2428414C2 (ru) * 2009-11-03 2011-09-10 Закрытое Акционерное Общество "Вертекс" Способ получения амидов креатина
UY34585A (es) * 2012-01-24 2013-09-02 Aicuris Gmbh & Co Kg Compuestos b-lactámicos sustituidos con amidina, su preparación y uso

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3579501A (en) * 1969-08-22 1971-05-18 Bristol Myers Co 6-(alpha-(3 - guanyl - 1 - ureido)phenyl- or thienyl-acetamido)penicillanic acids

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9827217B2 (en) 2015-08-25 2017-11-28 Rgenix, Inc. Pharmaceutically acceptable salts of B-guanidinopropionic acid with improved properties and uses thereof
US9884813B1 (en) 2017-03-01 2018-02-06 Rgenix, Inc. Pharmaceutically acceptable salts of B-guanidinopropionic acid with improved properties and uses thereof
US12011427B2 (en) 2019-12-11 2024-06-18 Inspirna, Inc. Methods of treating cancer

Also Published As

Publication number Publication date
US3870709A (en) 1975-03-11
GB1379502A (en) 1975-01-02
DE2304591A1 (de) 1973-09-06
JPS4896597A (xx) 1973-12-10
AU5086273A (en) 1974-07-11
FR2181713A1 (xx) 1973-12-07
AR196000A1 (es) 1973-11-23
AU473210B2 (en) 1976-06-17
ES411065A1 (es) 1976-04-16
CH561218A5 (xx) 1975-04-30
BE794886A (fr) 1973-08-02
FR2181713B1 (xx) 1976-10-22

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