CA1008863A - Azole derivatives - Google Patents

Azole derivatives

Info

Publication number
CA1008863A
CA1008863A CA144,331A CA144331A CA1008863A CA 1008863 A CA1008863 A CA 1008863A CA 144331 A CA144331 A CA 144331A CA 1008863 A CA1008863 A CA 1008863A
Authority
CA
Canada
Prior art keywords
azole derivatives
azole
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA144,331A
Other languages
English (en)
Other versions
CA144331S (en
Inventor
Johann Dahm
Joachim Borck
Albrecht Wild
Jan W. Hovy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Application granted granted Critical
Publication of CA1008863A publication Critical patent/CA1008863A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/36—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/46—Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA144,331A 1971-06-11 1972-06-09 Azole derivatives Expired CA1008863A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2129012A DE2129012A1 (de) 1971-06-11 1971-06-11 Azol-derivate

Publications (1)

Publication Number Publication Date
CA1008863A true CA1008863A (en) 1977-04-19

Family

ID=5810494

Family Applications (1)

Application Number Title Priority Date Filing Date
CA144,331A Expired CA1008863A (en) 1971-06-11 1972-06-09 Azole derivatives

Country Status (21)

Country Link
US (2) US3933840A (de)
JP (1) JPS5728705B1 (de)
AT (6) AT323158B (de)
AU (1) AU462556B2 (de)
BE (1) BE784682A (de)
BR (1) BR7203714D0 (de)
CA (1) CA1008863A (de)
CH (6) CH585213A5 (de)
CS (6) CS167987B2 (de)
DD (1) DD97206A5 (de)
DE (1) DE2129012A1 (de)
ES (2) ES403741A1 (de)
FR (1) FR2140632B1 (de)
GB (1) GB1331408A (de)
HU (1) HU166271B (de)
IL (1) IL39528A (de)
NL (1) NL7207784A (de)
PL (1) PL79513B1 (de)
RO (1) RO60483A (de)
SE (1) SE381467B (de)
ZA (1) ZA723502B (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2129012A1 (de) * 1971-06-11 1973-01-04 Merck Patent Gmbh Azol-derivate
US4089865A (en) * 1971-10-27 1978-05-16 Syntex (U.S.A.) Inc. Certain thiazole compounds
GB1507032A (en) * 1974-08-06 1978-04-12 Serono Lab 2-thiol-4,5-diphenyloxazole s-derivatives
DE2549998A1 (de) * 1975-11-07 1977-05-12 Merck Patent Gmbh Mittel zur hemmung der thrombozytenaggregation
IT1099996B (it) * 1978-10-17 1985-09-28 Anic Spa Derivati del 4,5-difenil-ossazolo 2-ammino o 2-tio sostituiti e procedimento per il loro ottenimento
DE3060330D1 (en) * 1979-04-06 1982-06-09 Bayer Ag Azolyloxy-acetamides, process for their preparation and their use as herbicides
DE2946524A1 (de) * 1979-11-17 1981-06-11 Bayer Ag, 5090 Leverkusen Azolyloxy-carbonsaeure-n-oxy-amide, verfahren zu ihrer herstellung und ihre verwendung als herbizide
US4451471A (en) * 1981-03-18 1984-05-29 Ciba-Geigy Corporation Certain 2,4,5-tri-substituted thiazoles, pharmaceutical compositions containing same and methods of using same
DE3336846A1 (de) * 1983-10-11 1985-04-25 Bayer Ag, 5090 Leverkusen Neue 2-mercaptothiazolderivate, verfahren zu deren herstellung sowie die verwendung von 2-mercaptothiazolderivaten in arzneimitteln
DE3508665A1 (de) * 1985-03-12 1986-09-18 Hoechst Ag, 6230 Frankfurt Heterocyclische sulfide und ihre anwendung als immunmodulatoren
GB8610432D0 (en) * 1986-04-29 1986-06-04 Akzo Nv Amino-thiazole & oxazole derivatives
USRE34242E (en) * 1986-04-29 1993-05-04 Akzo N.V. Amino-oxazole compounds having dopaminergic activity
DE3807232A1 (de) * 1988-03-05 1989-09-14 Bayer Ag Substituierte acrylsaeureester
JPH02145524A (ja) * 1988-11-29 1990-06-05 Katsumi Nagata 木酢液より得られる医薬品原料の製造方法
US5545755A (en) * 1989-05-31 1996-08-13 The Upjohn Company Therapeutically useful 2-aminotetralin derivatives
RU2086535C1 (ru) * 1989-05-31 1997-08-10 Дзе Апджон Компани Производные 1,2,3,4-тетрагидро-2-нафтиламина
NZ236474A (en) * 1989-12-20 1993-07-27 Bristol Myers Squibb Co 4,5-diphenyl-2-oxazole octanoic, nonanoic and decanoic acid and ester derivatives, preparation and pharmaceutical compositions thereof
US5274117A (en) * 1990-01-22 1993-12-28 Hoechst-Roussel Pharmaceuticals, Inc. Process for the enantioselective synthesis of intermediates used in the preparation of physostigmine
US5840915A (en) * 1990-01-22 1998-11-24 Hoechst Marion Roussel, Inc. Process for the enatioselective synthesis of intermediates used
FR2663331B1 (fr) * 1990-06-14 1994-05-06 Bellon Laboratoires Nouveaux derives de l'oxazole, leur preparation et les compositions pharmaceutiques qui les contiennent.
US5380738A (en) * 1993-05-21 1995-01-10 Monsanto Company 2-substituted oxazoles further substituted by 4-fluorophenyl and 4-methylsulfonylphenyl as antiinflammatory agents
US6515014B2 (en) 1995-06-02 2003-02-04 G. D. Searle & Co. Thiophene substituted hydroxamic acid derivatives as cyclooxygenase-2 and 5-lipoxygenase inhibitors
EP0828718A1 (de) 1995-06-02 1998-03-18 G.D. SEARLE & CO. Heterocyclo-substituierte hydroxaminsäurederivate als cyclooxygenase-2 und 5-lipoxygenase inhibitoren
US6512121B2 (en) 1998-09-14 2003-01-28 G.D. Searle & Co. Heterocyclo substituted hydroxamic acid derivatives as cyclooxygenase-2 and 5-lipoxygenase inhibitors
US6677364B2 (en) 1998-04-20 2004-01-13 G.D. Searle & Co. Substituted sulfonylphenylheterocycles as cyclooxygenase-2 and 5-lipoxygenase inhibitors
CA2344300A1 (en) 1998-09-17 2000-03-23 Jeffrey A. Robl Method for treating atherosclerosis employing an ap2 inhibitor and combination
US7358254B2 (en) 2001-07-13 2008-04-15 Bristol-Myers Squibb Company Method for treating atherosclerosis employing an aP2 inhibitor and combination
US7390824B1 (en) 1999-09-07 2008-06-24 Bristol-Myers Squibb Company Method for treating diabetes employing an aP2 inhibitor and combination
US20030105144A1 (en) 2001-04-17 2003-06-05 Ping Gao Stabilized oral pharmaceutical composition
US7329401B2 (en) * 2002-04-15 2008-02-12 The Regents Of The University Of California Cyclooxygenase-2 selective agents useful as imaging probes and related methods
TW200505446A (en) * 2003-01-17 2005-02-16 Fuj Isawa Pharmaceutical Co Ltd Inhibitor of cox
WO2023143741A1 (de) * 2022-01-28 2023-08-03 Symrise Ag Neue kühlstoffe und zubereitungen, die diese enthalten

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2513923A (en) * 1947-11-10 1950-07-04 Ilford Ltd Dyestuffs from s-(thiazolyl-2)-thioglycollic acid and method for preparing same
US3578671A (en) * 1967-11-06 1971-05-11 Wyeth John & Brother Ltd Oxazoles
DE2129012A1 (de) * 1971-06-11 1973-01-04 Merck Patent Gmbh Azol-derivate

Also Published As

Publication number Publication date
AU4285072A (en) 1973-12-06
HU166271B (de) 1975-02-28
ZA723502B (en) 1973-03-28
DE2129012A1 (de) 1973-01-04
DD97206A5 (de) 1973-04-20
US4051250A (en) 1977-09-27
FR2140632A1 (de) 1973-01-19
CS167989B2 (de) 1976-05-28
AT327891B (de) 1976-02-25
ES403741A1 (es) 1976-04-01
CH590856A5 (de) 1977-08-31
CS167988B2 (de) 1976-05-28
ATA136674A (de) 1975-05-15
AT328440B (de) 1976-03-25
ATA136574A (de) 1975-05-15
CH584700A5 (de) 1977-02-15
ATA136874A (de) 1975-05-15
AT327889B (de) 1976-02-25
RO60483A (de) 1976-08-15
IL39528A0 (en) 1972-07-26
CS167986B2 (de) 1976-05-28
AT323158B (de) 1975-06-25
CH584701A5 (de) 1977-02-15
CS167984B2 (de) 1976-05-28
CH585213A5 (de) 1977-02-28
AT327890B (de) 1976-02-25
CH584210A5 (de) 1977-01-31
US3933840A (en) 1976-01-20
IL39528A (en) 1976-08-31
NL7207784A (de) 1972-12-13
CH584702A5 (de) 1977-02-15
JPS5728705B1 (de) 1982-06-18
ATA489572A (de) 1975-06-15
BE784682A (fr) 1972-12-11
ATA136774A (de) 1975-05-15
CS167985B2 (de) 1976-05-28
FR2140632B1 (de) 1976-01-23
AT327892B (de) 1976-02-25
CS167987B2 (de) 1976-05-28
SE381467B (sv) 1975-12-08
PL79513B1 (de) 1975-06-30
ES439448A1 (es) 1977-03-01
GB1331408A (en) 1973-09-26
AU462556B2 (en) 1975-06-12
BR7203714D0 (pt) 1973-11-01

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