CA1005815A - Nonapeptide amide derivatives - Google Patents

Nonapeptide amide derivatives

Info

Publication number
CA1005815A
CA1005815A CA169,683A CA169683A CA1005815A CA 1005815 A CA1005815 A CA 1005815A CA 169683 A CA169683 A CA 169683A CA 1005815 A CA1005815 A CA 1005815A
Authority
CA
Canada
Prior art keywords
amide derivatives
nonapeptide amide
nonapeptide
derivatives
amide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA169,683A
Other languages
English (en)
Other versions
CA169683S (en
Inventor
Tsunehiko Fukuda
Mikihiko Obayashi
Susumu Shinagawa
Shigeru Kobayashi
Masahiko Fujino
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP4268672A external-priority patent/JPS5324423B2/ja
Priority claimed from JP11845272A external-priority patent/JPS5324424B2/ja
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of CA1005815A publication Critical patent/CA1005815A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/13—Luteinizing hormone-releasing hormone; related peptides
CA169,683A 1972-04-29 1973-04-27 Nonapeptide amide derivatives Expired CA1005815A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP4268672A JPS5324423B2 (de) 1972-04-29 1972-04-29
JP11845272A JPS5324424B2 (de) 1972-11-24 1972-11-24

Publications (1)

Publication Number Publication Date
CA1005815A true CA1005815A (en) 1977-02-22

Family

ID=26382407

Family Applications (1)

Application Number Title Priority Date Filing Date
CA169,683A Expired CA1005815A (en) 1972-04-29 1973-04-27 Nonapeptide amide derivatives

Country Status (17)

Country Link
US (1) US3853837A (de)
AT (1) AT333988B (de)
AU (1) AU453931B2 (de)
CA (1) CA1005815A (de)
CH (1) CH580065A5 (de)
CS (1) CS188162B2 (de)
DE (2) DE2321174C2 (de)
DK (1) DK147851C (de)
ES (1) ES414197A1 (de)
FI (1) FI56676C (de)
FR (1) FR2183021B1 (de)
GB (1) GB1403642A (de)
HU (1) HU168696B (de)
NL (2) NL176856C (de)
NO (1) NO139560C (de)
PL (1) PL95790B1 (de)
SE (1) SE397520B (de)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3931138A (en) * 1973-03-13 1976-01-06 Abbott Laboratories N-carbobenzoxy-pyroglutamyl-histidine
AT347054B (de) * 1973-09-29 1978-12-11 Takeda Chemical Industries Ltd Verfahren zur herstellung von neuen nonapeptidamid-derivaten
GB1532211A (en) * 1974-10-25 1978-11-15 Wellcome Found Lh-rh peptide analogues
US4338305A (en) * 1975-03-24 1982-07-06 American Home Products Corporation Use of LRH and LRH agonists
AU497512B2 (en) * 1975-04-15 1978-12-14 Ici Australia Limited Nona and deca-peptides
US4034082A (en) * 1976-03-01 1977-07-05 Abbott Laboratories Method to prevent reproduction in warm-blooded female animals with nonapeptides
DE2905502C2 (de) * 1979-02-14 1982-07-15 Hoechst Ag, 6000 Frankfurt Verfahren zur Herstellung von LH-RH bzw. LH-RH-Analoga und Pyroglutamyl-N↑i↑m↑-dinitrophenyl-histidin
DE3020941A1 (de) * 1980-06-03 1981-12-17 Hoechst Ag, 6000 Frankfurt Nonapeptid, verfahren zu seiner herstellung, dieses enthaltendes mittel und seine verwendung
US4675189A (en) * 1980-11-18 1987-06-23 Syntex (U.S.A.) Inc. Microencapsulation of water soluble active polypeptides
US4659696A (en) * 1982-04-30 1987-04-21 Takeda Chemical Industries, Ltd. Pharmaceutical composition and its nasal or vaginal use
HU193607B (en) * 1985-07-18 1987-11-30 Innofinance Altalanos Innovaci Process for production of sexual products applyable for natural or artificial insemination for mammates
US4897268A (en) * 1987-08-03 1990-01-30 Southern Research Institute Drug delivery system and method of making the same
US5068221A (en) * 1989-05-09 1991-11-26 Mathias John R Treatment of motility disorders with a gnrh analog
JP2653255B2 (ja) 1990-02-13 1997-09-17 武田薬品工業株式会社 長期徐放型マイクロカプセル
CA2050425A1 (en) 1990-09-03 1992-03-04 Yoshiaki Uda Pharmaceutical composition and its mucous use
NO302481B1 (no) 1990-10-16 1998-03-09 Takeda Chemical Industries Ltd Polymer for et preparat med forlenget frigjöring, samt preparat med forlenget frigjöring
US5434136A (en) * 1990-12-14 1995-07-18 Mathias; John R. Treatment of motility disorders with a GNRH analog
US5518730A (en) * 1992-06-03 1996-05-21 Fuisz Technologies Ltd. Biodegradable controlled release flash flow melt-spun delivery system
DE69316101T2 (de) 1992-08-07 1998-10-22 Takeda Chemical Industries Ltd Herstellung von Mikrokapseln, die wasserlösliche Arzneimittel enthalten
US5594091A (en) * 1994-02-21 1997-01-14 Takeda Chemical Industries, Ltd. Matrix for sustained-release preparation
US6117455A (en) * 1994-09-30 2000-09-12 Takeda Chemical Industries, Ltd. Sustained-release microcapsule of amorphous water-soluble pharmaceutical active agent
US5837281A (en) 1995-03-17 1998-11-17 Takeda Chemical Industries, Ltd. Stabilized interface for iontophoresis
US7833543B2 (en) * 1995-06-07 2010-11-16 Durect Corporation High viscosity liquid controlled delivery system and medical or surgical device
US6413536B1 (en) 1995-06-07 2002-07-02 Southern Biosystems, Inc. High viscosity liquid controlled delivery system and medical or surgical device
CA2192773C (en) 1995-12-15 2008-09-23 Hiroaki Okada Production of sustained-release preparation for injection
CA2192782C (en) 1995-12-15 2008-10-14 Nobuyuki Takechi Production of microspheres
CN1095681C (zh) * 1996-06-20 2002-12-11 久光制药株式会社 一种用于离子电渗疗法的装置结构
US20060025328A1 (en) * 1997-05-28 2006-02-02 Burns Patrick J Compositions suitable for controlled release of the hormone GnRH and its analogs
US6051558A (en) * 1997-05-28 2000-04-18 Southern Biosystems, Inc. Compositions suitable for controlled release of the hormone GnRH and its analogs
EP0882736A1 (de) * 1997-06-02 1998-12-09 Laboratoire Theramex S.A. Peptidanaloge des LH-RH, ihre Verwendungen und die sie enthaltenden pharmazeutischen Zusammensetzungen
JP4414517B2 (ja) 1999-09-01 2010-02-10 久光製薬株式会社 イオントフォレーシス用デバイス構造体
US20040001889A1 (en) 2002-06-25 2004-01-01 Guohua Chen Short duration depot formulations
SI2218448T1 (sl) 2002-12-13 2016-01-29 Durect Corporation Sistem za oralno dajanje zdravila, ki obsega tekoči nosilec materialov z visoko viskoznostjo
KR101351771B1 (ko) 2004-09-17 2014-02-17 듀렉트 코퍼레이션 바람직하게 ｓａｉｂ와 같은 당 에스테르를 포함하는지속적인 국소 마취제 조성물
US20070027105A1 (en) 2005-07-26 2007-02-01 Alza Corporation Peroxide removal from drug delivery vehicle
PT2117521E (pt) 2006-11-03 2012-09-10 Durect Corp Sistemas de administração transdérmica que compreendem bupivacaína
AU2008347158B8 (en) 2007-12-06 2013-08-22 Durect Corporation Oral pharmaceutical dosage forms
US20100260844A1 (en) 2008-11-03 2010-10-14 Scicinski Jan J Oral pharmaceutical dosage forms
EP2983468A4 (de) 2013-03-15 2016-09-07 Durect Corp Zusammensetzungen mit rheologiemodifikator zur reduzierung der auflösungsvariabilität
WO2021146215A1 (en) 2020-01-13 2021-07-22 Durect Corporation Sustained release drug delivery systems with reduced impurities and related methods

Also Published As

Publication number Publication date
DE2321174A1 (de) 1973-11-08
DK147851C (da) 1986-03-10
PL95790B1 (pl) 1977-11-30
NO139560C (no) 1979-04-04
NL930004I1 (nl) 1993-04-01
ES414197A1 (es) 1976-05-01
ATA377173A (de) 1976-04-15
SE397520B (sv) 1977-11-07
DK147851B (da) 1984-12-24
FI56676B (fi) 1979-11-30
NL176856C (nl) 1985-06-17
CH580065A5 (de) 1976-09-30
GB1403642A (en) 1975-08-28
AT333988B (de) 1976-12-27
FR2183021A1 (de) 1973-12-14
NO139560B (no) 1978-12-27
NL7305995A (de) 1973-10-31
AU5467673A (en) 1974-10-17
FI56676C (fi) 1980-03-10
DE2366379C2 (de) 1985-01-17
US3853837A (en) 1974-12-10
CS188162B2 (en) 1979-02-28
DE2321174C2 (de) 1982-04-15
HU168696B (de) 1976-06-28
FR2183021B1 (de) 1976-04-09
AU453931B2 (en) 1974-10-17

Similar Documents

Publication Publication Date Title
CA1005815A (en) Nonapeptide amide derivatives
AU467361B2 (en) Q-aryl-4-substituted piperidinoalkanol derivatives
CA1019738A (en) Isothiocyanopyridine derivatives
AU470719B2 (en) Oxazinoindole-and thiazinoinindole derivatives
AU467405B2 (en) Diphenylalkyllactamimide derivatives
CA1020946A (en) 1-phenoxy-3-phenoxyethylamino-2-propanol derivatives
ZA732564B (en) Novel nonapeptide amide derivatives
CA1006514A (en) Beta-aminoketone derivatives
AU470763B2 (en) Pyrano-and thiopyranoindole derivatives
CA1018161A (en) Indan-1-carboxamide derivatives
CA978526A (en) Pyrano- and thiopyranoindole derivatives
CA1016542A (en) Benzodiazocine derivatives
CA981684A (en) Cyclopenteno-quinolone derivatives
CA893174A (en) N-(p-substituted-aminophenyl)-alkylenimine
CA898253A (en) Styryl-naphthalene derivatives
CA904885A (en) 1-amino-3-phenoxy-2-propanol derivatives
CA892056A (en) Sulphonamidopyrazolinone derivatives
CA896560A (en) 6-phenyl-dihydropyridazine-3-one derivatives
AU477427B2 (en) 2-fluoro-substituted thiazanthene derivatives
CA917653A (en) N-sulphonamide-succinimide derivatives
CA891502A (en) Benhydrylquinuclidinol derivatives
CA899353A (en) 1-hydroxyproline derivatives
CA893701A (en) Triazolobenzodiazepinone derivatives
AU483221B2 (en) Benzo-di-pyran derivatives
CA912581A (en) Zearalane derivatives