CA1003835A - Indole derivatives having pharmacological activity - Google Patents

Indole derivatives having pharmacological activity

Info

Publication number
CA1003835A
CA1003835A CA192,435A CA192435A CA1003835A CA 1003835 A CA1003835 A CA 1003835A CA 192435 A CA192435 A CA 192435A CA 1003835 A CA1003835 A CA 1003835A
Authority
CA
Canada
Prior art keywords
pharmacological activity
indole derivatives
indole
derivatives
pharmacological
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA192,435A
Other languages
English (en)
Other versions
CA192435S (en
Inventor
Henri Inion
Marcel Descamps
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Labaz SA
Original Assignee
Labaz SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Labaz SA filed Critical Labaz SA
Application granted granted Critical
Publication of CA1003835A publication Critical patent/CA1003835A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA192,435A 1973-02-16 1974-02-13 Indole derivatives having pharmacological activity Expired CA1003835A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB786673A GB1436771A (en) 1973-02-16 1973-02-16 Indole derivatives and process for preparing the same

Publications (1)

Publication Number Publication Date
CA1003835A true CA1003835A (en) 1977-01-18

Family

ID=9841293

Family Applications (1)

Application Number Title Priority Date Filing Date
CA192,435A Expired CA1003835A (en) 1973-02-16 1974-02-13 Indole derivatives having pharmacological activity

Country Status (23)

Country Link
US (1) US3946029A (da)
JP (1) JPS5058076A (da)
AR (1) AR202639A1 (da)
AT (1) AT330776B (da)
BE (1) BE810759A (da)
CA (1) CA1003835A (da)
CH (1) CH580073A5 (da)
DE (1) DE2407465A1 (da)
DK (1) DK138076B (da)
ES (1) ES423288A1 (da)
FI (1) FI58123C (da)
FR (1) FR2218098B1 (da)
GB (1) GB1436771A (da)
HU (1) HU166731B (da)
IE (1) IE40378B1 (da)
IN (1) IN139121B (da)
NL (1) NL7401955A (da)
NO (1) NO140424C (da)
OA (1) OA04687A (da)
SE (1) SE390536B (da)
SU (1) SU543343A3 (da)
YU (1) YU36722B (da)
ZA (1) ZA74701B (da)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2334358A1 (fr) * 1975-12-12 1977-07-08 Sogeras Nouveaux medicaments derives de l'indole
ZA825413B (en) * 1981-08-26 1983-06-29 Pfizer Thromboxane synthetase inhibitors, processes for their production, and pharmaceutical compositions comprising them
JPS60142981A (ja) * 1983-12-28 1985-07-29 Yoshitomi Pharmaceut Ind Ltd ３−インド−ルカルボキサミド誘導体
US4581354A (en) * 1984-08-06 1986-04-08 Sterling Drug Inc. 3-arylcarbonyl- and 3-cycloalkylcarbonyl-1-aminoalkyl-1H-indoles, compositions and use
US4634776A (en) * 1984-08-06 1987-01-06 Sterling Drug, Inc. 3-arylcarbonyl-and 3-cycloalkylcarbonyl-1-aminoalkyl-1H-indoles
PH23498A (en) * 1984-08-06 1989-08-16 Sterling Drug Inc 3-carbonyl-1-aminoalkyl-1h-indoles,composition and use thereof
US5013732A (en) * 1984-08-06 1991-05-07 Sterling Drug Inc. 3-arylcarbonyl- and 3-cycloalkyl-carbonyl-1-aminoalkyl-1H-indoles
US4978664A (en) * 1984-08-06 1990-12-18 Sterling Drug Inc. 3-arylcarbonyl- and 3-cycloalkyl-carbonyl-1-aminoalkyl-1H-indole pharmaceutical compositions
USRE32761E (en) * 1984-08-06 1988-10-04 Sterling Drug Inc. 3-arylcarbonyl and 3-cycloalkylcarbonyl-1-aminoalkyl-1H-indoles, compositions and use
US4690943A (en) * 1984-09-19 1987-09-01 Pfizer Inc. Analgesic and antiinflammatory 1,3-diacyl-2-oxindole compounds
US4840950A (en) * 1987-02-11 1989-06-20 Sterling Drug Inc. 4-arylcarbonyl-1-[(4-morpholinyl)-lower-alkyl]-1H-indoles
US5068234A (en) * 1990-02-26 1991-11-26 Sterling Drug Inc. 3-arylcarbonyl-1-(c-attached-n-heteryl)-1h-indoles
US5081122A (en) * 1990-03-05 1992-01-14 Sterling Drug Inc. Antiglaucoma compositions containing 4-arylcarbonyl-1-(4-morpholinyl)-lower-alkyl)-1H-indoles and method of use thereof
US5013837A (en) * 1990-03-08 1991-05-07 Sterling Drug Inc. 3-Arylcarbonyl-1H-indole-containing compounds
US4973587A (en) * 1990-03-08 1990-11-27 Sterling Drug Inc. 3-arylcarbonyl-1-aminoalkyl-1H-indole-containing antiglaucoma method
CA2036307C (en) * 1990-03-08 2002-07-09 Susan Jean Ward 3-arylcarbonyl-1-aminoalkyl-1h-indole-containing antiglaucoma compositions and method
US6342611B1 (en) * 1997-10-10 2002-01-29 Cytovia, Inc. Fluorogenic or fluorescent reporter molecules and their applications for whole-cell fluorescence screening assays for capsases and other enzymes and the use thereof
DE69910373T2 (de) * 1998-05-04 2004-04-01 The University Of Connecticut, Farmington Analgetische und immunomodulierende cannabinoiden
US7589220B2 (en) * 1998-06-09 2009-09-15 University Of Connecticut Inhibitors of the anandamide transporter
US7897598B2 (en) * 1998-06-09 2011-03-01 Alexandros Makriyannis Inhibitors of the anandamide transporter
US7161016B1 (en) 1998-11-24 2007-01-09 University Of Connecticut Cannabimimetic lipid amides as useful medications
US7276613B1 (en) 1998-11-24 2007-10-02 University Of Connecticut Retro-anandamides, high affinity and stability cannabinoid receptor ligands
US7393842B2 (en) * 2001-08-31 2008-07-01 University Of Connecticut Pyrazole analogs acting on cannabinoid receptors
US6943266B1 (en) * 1999-10-18 2005-09-13 University Of Connecticut Bicyclic cannabinoid agonists for the cannabinoid receptor
US7741365B2 (en) * 1999-10-18 2010-06-22 University Of Connecticut Peripheral cannabinoid receptor (CB2) selective ligands
US6900236B1 (en) * 1999-10-18 2005-05-31 University Of Connecticut Cannabimimetic indole derivatives
US8084467B2 (en) * 1999-10-18 2011-12-27 University Of Connecticut Pyrazole derivatives as cannabinoid receptor antagonists
US7119108B1 (en) * 1999-10-18 2006-10-10 University Of Connecticut Pyrazole derivatives as cannabinoid receptor antagonists
JP2004532185A (ja) * 2001-01-26 2004-10-21 ユニバーシティ オブ コネチカット 新規なカンナビミメティックリガンド
DE60237431D1 (de) * 2001-01-29 2010-10-07 Univ Connecticut Rezeptor-selektive cannabimimetische aminoalkylindole
JP4312594B2 (ja) * 2001-07-13 2009-08-12 ユニバーシティ オブ コネチカット 新規な二環式及び三環式カンナビノイド
WO2003035005A2 (en) * 2001-10-26 2003-05-01 University Of Connecticut Heteroindanes: a new class of potent cannabimimetic ligands
EP1998766A2 (en) * 2005-12-16 2008-12-10 Ironwood Pharmaceuticals, Inc. Useful indole compounds
WO2007112322A2 (en) * 2006-03-28 2007-10-04 Allergan, Inc. Indole compounds having sphingosine-1-phosphate (s1p) receptor agonist and/or antagonist biological activity
JP5406716B2 (ja) 2006-08-07 2014-02-05 アイアンウッド ファーマシューティカルズ インコーポレイテッド インドール化合物
AR084433A1 (es) 2010-12-22 2013-05-15 Ironwood Pharmaceuticals Inc Inhibidores de la faah y composiciones farmaceuticas que los contienen
CN108239083B (zh) * 2016-12-26 2021-08-17 阿里根公司 芳香烃受体调节剂
TW201925194A (zh) 2017-11-20 2019-07-01 美商雅里俊公司 吲哚化合物及其用途
EP3956327A1 (en) 2019-04-15 2022-02-23 Ariagen, Inc. Chiral indole compounds and their use

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL100127C (da) * 1954-04-28
US3557142A (en) * 1968-02-20 1971-01-19 Sterling Drug Inc 4,5,6,7-tetrahydro-indole-lower-alkanoic acids and esters
US3686213A (en) * 1970-08-28 1972-08-22 American Cyanamid Co Substituted aminoethyl indoles

Also Published As

Publication number Publication date
YU39474A (en) 1982-02-25
HU166731B (da) 1975-05-28
DK138076B (da) 1978-07-10
ES423288A1 (es) 1976-04-16
BE810759A (fr) 1974-08-08
NO740516L (no) 1974-08-19
YU36722B (en) 1984-08-31
DE2407465A1 (de) 1974-08-22
IE40378L (en) 1974-08-16
CH580073A5 (da) 1976-09-30
IE40378B1 (en) 1979-05-23
SU543343A3 (ru) 1977-01-15
ATA119174A (de) 1975-10-15
NO140424C (no) 1979-08-29
AU6536374A (en) 1975-08-14
GB1436771A (en) 1976-05-26
AR202639A1 (es) 1975-06-30
DK138076C (da) 1978-11-27
FI58123B (fi) 1980-08-29
FI58123C (fi) 1980-12-10
JPS5058076A (da) 1975-05-20
NO140424B (no) 1979-05-21
ZA74701B (en) 1974-12-24
IN139121B (da) 1976-05-08
FR2218098A1 (da) 1974-09-13
US3946029A (en) 1976-03-23
FR2218098B1 (da) 1978-03-24
OA04687A (fr) 1980-07-31
AT330776B (de) 1976-07-26
SE390536B (sv) 1976-12-27
NL7401955A (da) 1974-08-20

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