CA1002537A - Racemic and optically active 1-(2,5-dichlorophenoxy)-3-tert. butylamino-2-propanol and its salts - Google Patents

Racemic and optically active 1-(2,5-dichlorophenoxy)-3-tert. butylamino-2-propanol and its salts

Info

Publication number
CA1002537A
CA1002537A CA137,222A CA137222A CA1002537A CA 1002537 A CA1002537 A CA 1002537A CA 137222 A CA137222 A CA 137222A CA 1002537 A CA1002537 A CA 1002537A
Authority
CA
Canada
Prior art keywords
dichlorophenoxy
butylamino
racemic
propanol
tert
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA137,222A
Inventor
Istvan Polgari
Marianne Kurti
Istvan Elekes
Marton Fekete
Andor Hajos
Sandor Elek
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Richter Gedeon Vegyeszeti Gyar RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszeti Gyar RT filed Critical Richter Gedeon Vegyeszeti Gyar RT
Application granted granted Critical
Publication of CA1002537A publication Critical patent/CA1002537A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/28—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
    • C07C217/30—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/32—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
    • C07C217/34—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by halogen atoms, by trihalomethyl, nitro or nitroso groups, or by singly-bound oxygen atoms
CA137,222A 1971-03-17 1972-03-16 Racemic and optically active 1-(2,5-dichlorophenoxy)-3-tert. butylamino-2-propanol and its salts Expired CA1002537A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HUGO001156 1971-03-17

Publications (1)

Publication Number Publication Date
CA1002537A true CA1002537A (en) 1976-12-28

Family

ID=10996691

Family Applications (1)

Application Number Title Priority Date Filing Date
CA137,222A Expired CA1002537A (en) 1971-03-17 1972-03-16 Racemic and optically active 1-(2,5-dichlorophenoxy)-3-tert. butylamino-2-propanol and its salts

Country Status (19)

Country Link
JP (1) JPS5310581B1 (en)
AT (1) AT316515B (en)
AU (1) AU461159B2 (en)
BE (1) BE780719A (en)
CA (1) CA1002537A (en)
CH (1) CH569692A5 (en)
CS (1) CS163270B2 (en)
DK (1) DK133872B (en)
ES (1) ES401235A1 (en)
FI (1) FI55025C (en)
FR (1) FR2130284B1 (en)
GB (1) GB1337921A (en)
IL (1) IL38870A (en)
NL (1) NL170626C (en)
NO (1) NO134836C (en)
PL (1) PL88985B1 (en)
SE (1) SE384021B (en)
SU (1) SU496721A3 (en)
YU (1) YU35435B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU172137B (en) 1976-03-02 1978-06-28 Gyogyszerkutato Intezet Process for preparing substituted derivatives of the phenoxy-propanolamine

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1236523C2 (en) * 1962-02-15 1975-06-12 Sanol-Arzneimittel Dr. Schwarz Gmbh, 4019 Monheim PROCESS FOR THE PRODUCTION OF BASIC PHENYLAETHERS AND THEIR SALTS

Also Published As

Publication number Publication date
NL170626B (en) 1982-07-01
PL88985B1 (en) 1976-10-30
DK133872C (en) 1976-12-27
IL38870A0 (en) 1972-05-30
AU461159B2 (en) 1975-04-29
YU63972A (en) 1980-06-30
ES401235A1 (en) 1975-02-16
NL170626C (en) 1982-12-01
YU35435B (en) 1981-02-28
FI55025B (en) 1979-01-31
FR2130284A1 (en) 1972-11-03
AT316515B (en) 1974-07-10
SU496721A3 (en) 1975-12-25
DE2213044B2 (en) 1977-05-26
FI55025C (en) 1979-05-10
NO134836C (en) 1976-12-21
BE780719A (en) 1972-07-03
NO134836B (en) 1976-09-13
SE384021B (en) 1976-04-12
DE2213044A1 (en) 1972-09-28
CH569692A5 (en) 1975-11-28
AU3965972A (en) 1973-09-13
GB1337921A (en) 1973-11-21
JPS5310581B1 (en) 1978-04-14
CS163270B2 (en) 1975-08-29
NL7203323A (en) 1972-09-19
DK133872B (en) 1976-08-02
FR2130284B1 (en) 1975-10-10
IL38870A (en) 1975-08-31

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