BRPI1013227A2 - pró-fármacos transportadores de interferon alfa - Google Patents
pró-fármacos transportadores de interferon alfaInfo
- Publication number
- BRPI1013227A2 BRPI1013227A2 BRPI1013227A BRPI1013227A BRPI1013227A2 BR PI1013227 A2 BRPI1013227 A2 BR PI1013227A2 BR PI1013227 A BRPI1013227 A BR PI1013227A BR PI1013227 A BRPI1013227 A BR PI1013227A BR PI1013227 A2 BRPI1013227 A2 BR PI1013227A2
- Authority
- BR
- Brazil
- Prior art keywords
- transporter
- prodrugs
- interferon alpha
- interferon
- alpha
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09154449 | 2009-03-05 | ||
| EP09180477 | 2009-12-22 | ||
| PCT/EP2010/052745 WO2010100220A1 (en) | 2009-03-05 | 2010-03-04 | Interferon alpha carrier prodrugs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI1013227A2 true BRPI1013227A2 (pt) | 2016-03-29 |
Family
ID=42041523
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI1013227A BRPI1013227A2 (pt) | 2009-03-05 | 2010-03-04 | pró-fármacos transportadores de interferon alfa |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20120058084A1 (pt) |
| EP (1) | EP2403537A1 (pt) |
| JP (1) | JP2012519666A (pt) |
| CN (1) | CN102413843A (pt) |
| AU (1) | AU2010220324A1 (pt) |
| BR (1) | BRPI1013227A2 (pt) |
| CA (1) | CA2753001A1 (pt) |
| MX (1) | MX2011008963A (pt) |
| RU (1) | RU2011140219A (pt) |
| WO (1) | WO2010100220A1 (pt) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3543256A1 (en) * | 2009-01-12 | 2019-09-25 | Cytomx Therapeutics Inc. | Modified antibody compositions, methods of making and using thereof |
| CA2769340C (en) | 2009-07-31 | 2018-09-11 | Harald Rau | Prodrugs comprising an insulin linker conjugate |
| SG178195A1 (en) | 2009-07-31 | 2012-03-29 | Sanofi Aventis Deutschland | Long acting insulin composition |
| WO2011042453A1 (en) | 2009-10-06 | 2011-04-14 | Ascendis Pharma As | Subcutaneous paliperidone composition |
| CA2776723C (en) | 2009-10-29 | 2018-09-25 | Ascendis Pharma As | Sterilization of biodegradable hydrogels |
| CN102711733A (zh) | 2009-12-15 | 2012-10-03 | 阿森迪斯药物股份有限公司 | 瞬时连接于聚合物载体的干生长激素组合物 |
| EP2525829A1 (en) | 2010-01-22 | 2012-11-28 | Ascendis Pharma A/S | Dipeptide-based prodrug linkers for aromatic amine-containing drugs |
| EP2525831B1 (en) | 2010-01-22 | 2019-05-15 | Ascendis Pharma A/S | Carrier-linked carbamate prodrug linkers |
| WO2011089216A1 (en) | 2010-01-22 | 2011-07-28 | Ascendis Pharma As | Dipeptide-based prodrug linkers for aliphatic amine-containing drugs |
| PL2616101T3 (pl) | 2010-09-14 | 2015-01-30 | Hoffmann La Roche | Sposób oczyszczania pegylowanej erytropoetyny |
| EP2438930A1 (en) | 2010-09-17 | 2012-04-11 | Sanofi-Aventis Deutschland GmbH | Prodrugs comprising an exendin linker conjugate |
| FR2975301B1 (fr) | 2011-05-20 | 2013-05-24 | Flamel Tech Sa | Composition comprenant un interferon alpha |
| DK2583680T1 (da) | 2011-10-21 | 2015-01-19 | Abbvie Inc | Mono (PSI-7977) eller kombinationsbehandling af DAA til anvendelse ved behandling af HCV |
| CN104383541A (zh) | 2011-10-21 | 2015-03-04 | 艾伯维公司 | 用于治疗hcv的包含至少两种直接抗病毒剂和利巴韦林但无干扰素的方法 |
| US8466159B2 (en) | 2011-10-21 | 2013-06-18 | Abbvie Inc. | Methods for treating HCV |
| US8492386B2 (en) | 2011-10-21 | 2013-07-23 | Abbvie Inc. | Methods for treating HCV |
| US8383093B1 (en) | 2011-11-01 | 2013-02-26 | Serina Therapeutics, Inc. | Subcutaneous delivery of poly(oxazoline) conjugates |
| MX363462B (es) * | 2012-10-11 | 2019-03-25 | Ascendis Pharma As | Diagnostico, prevencion y tratamiento de enfermedades de la articulacion. |
| EP3220892B1 (en) | 2014-11-21 | 2021-10-13 | Ascendis Pharma Endocrinology Division A/S | Long-acting growth hormone dosage forms |
| CA3022119A1 (en) | 2016-04-28 | 2017-11-02 | Emory University | Alkyne containing nucleotide and nucleoside therapeutic compositions and uses related thereto |
| KR20210153092A (ko) | 2019-04-15 | 2021-12-16 | 퀴셀 세라퓨틱스 엘엘씨 | 암 치료에 사용하기 위한, 마스킹된 유형 i 인터페론(ifna 및 ifnb) 및 종양 항원에 대한 항체를 포함하는 융합 단백질 조성물 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3812507A1 (de) | 1988-04-15 | 1989-10-26 | Sachsenwerk Ag | Schaltfeld fuer eine gekapselte mittelspannungs-schaltanlage |
| DE19510438A1 (de) | 1995-03-22 | 1996-09-26 | Basf Ag | Verfahren zur Herstellung von 1,4-Butandiol und Tetrahydrofuran aus Furan |
| IL119029A0 (en) | 1996-08-07 | 1996-11-14 | Yeda Res & Dev | Long-acting drugs and pharamaceutical compositions comprising them |
| CA2312975C (en) | 1997-12-17 | 2012-08-21 | Enzon, Inc. | Polymeric prodrugs of amino- and hydroxyl-containing bioactive agents |
| EP1243276A1 (en) | 2001-03-23 | 2002-09-25 | Franciscus Marinus Hendrikus De Groot | Elongated and multiple spacers containing activatible prodrugs |
| AU2003256038A1 (en) | 2002-08-30 | 2004-03-19 | Ramot At Tel Aviv University Ltd. | Self-immolative dendrimers releasing many active moieties upon a single activating event |
| AU2003282624A1 (en) | 2002-11-14 | 2004-06-03 | Syntarga B.V. | Prodrugs built as multiple self-elimination-release spacers |
| JP4698579B2 (ja) * | 2003-04-08 | 2011-06-08 | イエダ リサーチ アンド デベロップメント カンパニー リミテッド | 可逆的ｐｅｇ化薬物 |
| EP1525890A1 (en) | 2003-10-02 | 2005-04-27 | Complex Biosystems GmbH | Protein-Proteophore complexes |
| ES2741524T3 (es) | 2004-03-23 | 2020-02-11 | Ascendis Pharma Gmbh | Profármaco polimérico con un enlazador autoinmolador |
| EP1625855A1 (en) * | 2004-08-13 | 2006-02-15 | Complex Biosystems GmbH | Polymeric prodrug with a self-immolative linker |
| US7968085B2 (en) | 2004-07-05 | 2011-06-28 | Ascendis Pharma A/S | Hydrogel formulations |
| EP1679065A1 (en) | 2005-01-07 | 2006-07-12 | OctoPlus Sciences B.V. | Controlled release compositions for interferon based on PEGT/PBT block copolymers |
| GB2427360A (en) | 2005-06-22 | 2006-12-27 | Complex Biosystems Gmbh | Aliphatic prodrug linker |
-
2010
- 2010-03-04 JP JP2011552445A patent/JP2012519666A/ja active Pending
- 2010-03-04 CA CA2753001A patent/CA2753001A1/en not_active Abandoned
- 2010-03-04 BR BRPI1013227A patent/BRPI1013227A2/pt not_active Application Discontinuation
- 2010-03-04 EP EP10706648A patent/EP2403537A1/en not_active Withdrawn
- 2010-03-04 US US13/254,869 patent/US20120058084A1/en not_active Abandoned
- 2010-03-04 MX MX2011008963A patent/MX2011008963A/es not_active Application Discontinuation
- 2010-03-04 CN CN2010800192302A patent/CN102413843A/zh active Pending
- 2010-03-04 WO PCT/EP2010/052745 patent/WO2010100220A1/en active Application Filing
- 2010-03-04 AU AU2010220324A patent/AU2010220324A1/en not_active Abandoned
- 2010-03-04 RU RU2011140219/15A patent/RU2011140219A/ru not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US20120058084A1 (en) | 2012-03-08 |
| JP2012519666A (ja) | 2012-08-30 |
| EP2403537A1 (en) | 2012-01-11 |
| WO2010100220A1 (en) | 2010-09-10 |
| CN102413843A (zh) | 2012-04-11 |
| AU2010220324A1 (en) | 2011-09-01 |
| RU2011140219A (ru) | 2013-04-10 |
| MX2011008963A (es) | 2012-02-01 |
| CA2753001A1 (en) | 2010-09-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
| B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] | ||
| B15K | Others concerning applications: alteration of classification |
Ipc: A61K 47/60 (2017.01) |