BRPI1010514A2 - derivados de indol e métodos para tratamento antiviral - Google Patents
derivados de indol e métodos para tratamento antiviralInfo
- Publication number
- BRPI1010514A2 BRPI1010514A2 BRPI1010514A BRPI1010514A BRPI1010514A2 BR PI1010514 A2 BRPI1010514 A2 BR PI1010514A2 BR PI1010514 A BRPI1010514 A BR PI1010514A BR PI1010514 A BRPI1010514 A BR PI1010514A BR PI1010514 A2 BRPI1010514 A2 BR PI1010514A2
- Authority
- BR
- Brazil
- Prior art keywords
- methods
- indole derivatives
- antiviral treatment
- antiviral
- treatment
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Pulmonology (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US16689309P | 2009-04-06 | 2009-04-06 | |
PCT/US2010/029923 WO2010117932A1 (en) | 2009-04-06 | 2010-04-05 | Indole derivatives and methods for antiviral treatment |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI1010514A2 true BRPI1010514A2 (pt) | 2019-09-24 |
Family
ID=42257856
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI1010514A BRPI1010514A2 (pt) | 2009-04-06 | 2010-04-05 | derivados de indol e métodos para tratamento antiviral |
Country Status (21)
Country | Link |
---|---|
US (1) | US8735414B2 (pt) |
EP (1) | EP2417122A1 (pt) |
JP (1) | JP2012522806A (pt) |
KR (1) | KR20120007026A (pt) |
CN (1) | CN102695704A (pt) |
AR (1) | AR076265A1 (pt) |
AU (1) | AU2010234650A1 (pt) |
BR (1) | BRPI1010514A2 (pt) |
CA (1) | CA2757640A1 (pt) |
CO (1) | CO6450616A2 (pt) |
CR (1) | CR20110542A (pt) |
EC (1) | ECSP11011434A (pt) |
IL (1) | IL215559A0 (pt) |
MX (1) | MX2011010482A (pt) |
NI (1) | NI201100178A (pt) |
NZ (1) | NZ596144A (pt) |
RU (1) | RU2011144819A (pt) |
SG (2) | SG175048A1 (pt) |
TW (1) | TWI427076B (pt) |
WO (1) | WO2010117932A1 (pt) |
ZA (1) | ZA201108107B (pt) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5965484B2 (ja) | 2012-07-27 | 2016-08-03 | 佐藤製薬株式会社 | ジフルオロメチレン化合物 |
CA3036776A1 (en) | 2016-09-16 | 2018-03-22 | Sumitomo Chemical Company, Limited | Heterocyclic compound, and harmful-arthropod-controlling agent containing same |
WO2018213365A1 (en) * | 2017-05-15 | 2018-11-22 | Dana-Farber Cancer Institute, Inc. | Compounds for treating dengue virus infection and other viral infections |
RS65335B1 (sr) | 2018-10-05 | 2024-04-30 | Annapurna Bio Inc | Jedinjenja i kompozicije za lečenje stanja povezanih sa aktivnošću receptora apj |
CN113135900B (zh) * | 2021-03-12 | 2022-05-24 | 中山大学 | 吲哚嘧啶类化合物及其合成方法和应用 |
CN112891343B (zh) * | 2021-03-22 | 2022-04-01 | 华中农业大学 | 3-吲哚乙腈在制备抑制新型冠状病毒SARS-CoV-2药物中的应用 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TR200103147T1 (tr) * | 1999-12-27 | 2002-06-21 | Japan Tobacco Inc. | Kaynaşık halkalı bileşikler ve bunların ilaç olarak kullanımı. |
US7223785B2 (en) * | 2003-01-22 | 2007-05-29 | Boehringer Ingelheim International Gmbh | Viral polymerase inhibitors |
AU2004251175A1 (en) * | 2003-06-05 | 2005-01-06 | Merck & Co., Inc. | Substituted indoles and a process for preparing substituted indoles |
US20050119318A1 (en) * | 2003-10-31 | 2005-06-02 | Hudyma Thomas W. | Inhibitors of HCV replication |
US7772271B2 (en) * | 2004-07-14 | 2010-08-10 | Ptc Therapeutics, Inc. | Methods for treating hepatitis C |
JP2008506702A (ja) * | 2004-07-14 | 2008-03-06 | ピーティーシー セラピューティクス,インコーポレーテッド | C型肝炎を治療するための方法 |
EP2527337A1 (en) | 2005-04-14 | 2012-11-28 | Bristol-Myers Squibb Company | Inhibitors of 11-beta hydroxysteroid dehydrogenase type I |
WO2007027454A1 (en) * | 2005-08-30 | 2007-03-08 | Bristol-Myers Squibb Company | Heterocyclic dihydropyrimidine compounds |
WO2008009079A2 (en) * | 2006-07-20 | 2008-01-24 | Gilead Sciences, Inc. | Substituted pteridines useful for the treatment and prevention of viral infections |
CL2008001257A1 (es) * | 2007-05-04 | 2008-07-04 | Wyeth Corp | Compuestos triciclicos, inhibidores de metaloproteinasas matriciales; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como artritis reumatoide, osteoartritis, aterosclerosis, cancer de pulmon, entre otras. |
AR072297A1 (es) * | 2008-06-27 | 2010-08-18 | Novartis Ag | Derivados de indol-2-il-piridin-3-ilo, composicion farmaceutica que los comprende y su uso en medicamentos para el tratamiento de enfermedades mediadas por la sintasa aldosterona. |
WO2010041983A1 (ru) * | 2008-10-06 | 2010-04-15 | Алла Хем, Ллс | Замещенные 3-арилсульфoнил-пиpaзoлo[1,5-a]пиpимидины, антагонисты серотониновых 5-ht6 рецепторов, способы их получения и применения |
-
2010
- 2010-04-05 BR BRPI1010514A patent/BRPI1010514A2/pt not_active IP Right Cessation
- 2010-04-05 AU AU2010234650A patent/AU2010234650A1/en not_active Abandoned
- 2010-04-05 SG SG2011072170A patent/SG175048A1/en unknown
- 2010-04-05 JP JP2012503765A patent/JP2012522806A/ja not_active Ceased
- 2010-04-05 CA CA2757640A patent/CA2757640A1/en not_active Abandoned
- 2010-04-05 WO PCT/US2010/029923 patent/WO2010117932A1/en active Application Filing
- 2010-04-05 RU RU2011144819/04A patent/RU2011144819A/ru not_active Application Discontinuation
- 2010-04-05 NZ NZ596144A patent/NZ596144A/en not_active IP Right Cessation
- 2010-04-05 US US13/259,717 patent/US8735414B2/en not_active Expired - Fee Related
- 2010-04-05 SG SG2011072162A patent/SG175047A1/en unknown
- 2010-04-05 MX MX2011010482A patent/MX2011010482A/es not_active Application Discontinuation
- 2010-04-05 EP EP10714125A patent/EP2417122A1/en not_active Withdrawn
- 2010-04-05 CN CN2010800251546A patent/CN102695704A/zh active Pending
- 2010-04-05 KR KR1020117026150A patent/KR20120007026A/ko not_active Application Discontinuation
- 2010-04-06 AR ARP100101146A patent/AR076265A1/es not_active Application Discontinuation
- 2010-04-06 TW TW099110638A patent/TWI427076B/zh not_active IP Right Cessation
-
2011
- 2011-10-04 NI NI201100178A patent/NI201100178A/es unknown
- 2011-10-05 IL IL215559A patent/IL215559A0/en unknown
- 2011-10-18 CR CR20110542A patent/CR20110542A/es unknown
- 2011-11-01 CO CO11147742A patent/CO6450616A2/es active IP Right Grant
- 2011-11-01 EC EC2011011434A patent/ECSP11011434A/es unknown
- 2011-11-04 ZA ZA2011/08107A patent/ZA201108107B/en unknown
Also Published As
Publication number | Publication date |
---|---|
US8735414B2 (en) | 2014-05-27 |
KR20120007026A (ko) | 2012-01-19 |
US20120184574A1 (en) | 2012-07-19 |
JP2012522806A (ja) | 2012-09-27 |
CR20110542A (es) | 2012-01-30 |
RU2011144819A (ru) | 2013-05-20 |
AU2010234650A1 (en) | 2011-11-03 |
ZA201108107B (en) | 2013-01-30 |
NZ596144A (en) | 2014-01-31 |
TW201103900A (en) | 2011-02-01 |
ECSP11011434A (es) | 2011-12-30 |
TWI427076B (zh) | 2014-02-21 |
AR076265A1 (es) | 2011-06-01 |
CO6450616A2 (es) | 2012-05-31 |
CN102695704A (zh) | 2012-09-26 |
SG175047A1 (en) | 2011-11-28 |
NI201100178A (es) | 2012-01-23 |
MX2011010482A (es) | 2012-01-30 |
IL215559A0 (en) | 2011-12-29 |
EP2417122A1 (en) | 2012-02-15 |
WO2010117932A1 (en) | 2010-10-14 |
CA2757640A1 (en) | 2010-10-14 |
SG175048A1 (en) | 2011-11-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] | ||
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2543 DE 01-10-2019 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |