BRPI1010512A2 - "método ex vivo para avaliar a eficácia de um tratamento envolvendo a administração de uma composição imunogênica a um paciente, e, uso de níveis de linfócitos t ativados (cd3 + cd69+) como um biomarcador" - Google Patents
"método ex vivo para avaliar a eficácia de um tratamento envolvendo a administração de uma composição imunogênica a um paciente, e, uso de níveis de linfócitos t ativados (cd3 + cd69+) como um biomarcador"Info
- Publication number
- BRPI1010512A2 BRPI1010512A2 BRPI1010512A BRPI1010512A BRPI1010512A2 BR PI1010512 A2 BRPI1010512 A2 BR PI1010512A2 BR PI1010512 A BRPI1010512 A BR PI1010512A BR PI1010512 A BRPI1010512 A BR PI1010512A BR PI1010512 A2 BRPI1010512 A2 BR PI1010512A2
- Authority
- BR
- Brazil
- Prior art keywords
- biomarker
- assessing
- efficacy
- administration
- patient
- Prior art date
Links
- 210000001744 T-lymphocyte Anatomy 0.000 title 1
- 239000000090 biomarker Substances 0.000 title 1
- 230000002163 immunogen Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001169—Tumor associated carbohydrates
- A61K39/00117—Mucins, e.g. MUC-1
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5047—Cells of the immune system
- G01N33/505—Cells of the immune system involving T-cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
- G01N2333/7051—T-cell receptor (TcR)-CD3 complex
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/7056—Selectin superfamily, e.g. LAM-1, GlyCAM, ELAM-1, PADGEM
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP09305328 | 2009-04-17 | ||
PCT/EP2010/054743 WO2010119003A1 (en) | 2009-04-17 | 2010-04-12 | Biomarker for monitoring patients |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI1010512A2 true BRPI1010512A2 (pt) | 2016-03-15 |
Family
ID=42270292
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI1010512A BRPI1010512A2 (pt) | 2009-04-17 | 2010-04-12 | "método ex vivo para avaliar a eficácia de um tratamento envolvendo a administração de uma composição imunogênica a um paciente, e, uso de níveis de linfócitos t ativados (cd3 + cd69+) como um biomarcador" |
Country Status (27)
Country | Link |
---|---|
US (2) | US20120058493A1 (pt) |
EP (1) | EP2419728B1 (pt) |
JP (1) | JP5661738B2 (pt) |
KR (1) | KR20120027146A (pt) |
CN (1) | CN102395883B (pt) |
AU (1) | AU2010237215B2 (pt) |
BR (1) | BRPI1010512A2 (pt) |
CA (1) | CA2759050A1 (pt) |
CO (1) | CO6440591A2 (pt) |
CR (1) | CR20110513A (pt) |
CY (1) | CY1114910T1 (pt) |
DK (1) | DK2419728T3 (pt) |
ES (1) | ES2445146T3 (pt) |
HK (1) | HK1163246A1 (pt) |
HR (1) | HRP20140262T1 (pt) |
IL (1) | IL214917A (pt) |
MX (1) | MX2011010920A (pt) |
NZ (1) | NZ594896A (pt) |
PL (1) | PL2419728T3 (pt) |
PT (1) | PT2419728E (pt) |
RU (1) | RU2555340C2 (pt) |
SG (1) | SG175060A1 (pt) |
SI (1) | SI2419728T1 (pt) |
SM (1) | SMT201400046B (pt) |
TW (1) | TWI426270B (pt) |
WO (1) | WO2010119003A1 (pt) |
ZA (1) | ZA201107545B (pt) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP6375947B2 (ja) * | 2012-05-11 | 2018-08-22 | 味の素株式会社 | 取得方法、評価装置、評価方法、評価プログラム、評価システムおよび端末装置 |
US20140244556A1 (en) * | 2013-02-27 | 2014-08-28 | Abdul Saleh | Methods for and apparatus generating automated pharmaco genetics correlation |
WO2019113449A1 (en) * | 2017-12-08 | 2019-06-13 | Stc.Unm | In vivo imaging of tumor infiltration leukocytes |
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US4769330A (en) | 1981-12-24 | 1988-09-06 | Health Research, Incorporated | Modified vaccinia virus and methods for making and using the same |
IL73534A (en) | 1983-11-18 | 1990-12-23 | Riker Laboratories Inc | 1h-imidazo(4,5-c)quinoline-4-amines,their preparation and pharmaceutical compositions containing certain such compounds |
FR2643817B1 (fr) | 1989-03-06 | 1993-12-17 | Transgene Sa | Composition pharmaceutique, utile a titre preventif ou curatif contre les tumeurs induites par les papillomavirus |
DE3642912A1 (de) | 1986-12-16 | 1988-06-30 | Leybold Ag | Messeinrichtung fuer paramagnetische messgeraete mit einer messkammer |
US6054438A (en) | 1987-01-07 | 2000-04-25 | Imperial Cancer Research Technology Limited | Nucleic acid fragments encoding portions of the core protein of the human mammary epithelial mucin |
FR2632863B2 (fr) | 1987-10-29 | 1990-08-31 | Transgene Sa | Virus du fowlpox recombinant et vaccins derives de ces virus |
US5100587A (en) | 1989-11-13 | 1992-03-31 | The United States Of America As Represented By The Department Of Energy | Solid-state radioluminescent zeolite-containing composition and light sources |
FR2668064B1 (fr) | 1990-10-23 | 1994-12-16 | Transgene Sa | Composition pharmaceutique pour le traitement ou la prevention d'une tumeur maligne. |
US5756102A (en) | 1990-11-20 | 1998-05-26 | Virogenetics Corporation | Poxvirus-canine distemper virus (CDV) recombinants and compositions and methods employing the recombinants |
US5389640A (en) | 1991-03-01 | 1995-02-14 | Minnesota Mining And Manufacturing Company | 1-substituted, 2-substituted 1H-imidazo[4,5-c]quinolin-4-amines |
EP0575491B1 (en) | 1991-03-07 | 2003-08-13 | Virogenetics Corporation | Genetically engineered vaccine strain |
US5179993A (en) | 1991-03-26 | 1993-01-19 | Hughes Aircraft Company | Method of fabricating anisometric metal needles and birefringent suspension thereof in dielectric fluid |
US6013638A (en) | 1991-10-02 | 2000-01-11 | The United States Of America As Represented By The Department Of Health And Human Services | Adenovirus comprising deletions on the E1A, E1B and E3 regions for transfer of genes to the lung |
FR2705686B1 (fr) | 1993-05-28 | 1995-08-18 | Transgene Sa | Nouveaux adénovirus défectifs et lignées de complémentation correspondantes. |
US6133028A (en) | 1993-05-28 | 2000-10-17 | Transgene S.A. | Defective adenoviruses and corresponding complementation lines |
US5698443A (en) | 1995-06-27 | 1997-12-16 | Calydon, Inc. | Tissue specific viral vectors |
EP0772619B2 (en) | 1994-07-15 | 2010-12-08 | The University of Iowa Research Foundation | Immunomodulatory oligonucleotides |
US20030026782A1 (en) | 1995-02-07 | 2003-02-06 | Arthur M. Krieg | Immunomodulatory oligonucleotides |
US6045802A (en) * | 1994-10-03 | 2000-04-04 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Enhanced immune response to an antigen by a composition of a recombinant virus expressing the antigen with a recombinant virus expressing an immunostimulatory molecule |
US5998205A (en) | 1994-11-28 | 1999-12-07 | Genetic Therapy, Inc. | Vectors for tissue-specific replication |
US6638762B1 (en) | 1994-11-28 | 2003-10-28 | Genetic Therapy, Inc. | Tissue-vectors specific replication and gene expression |
FR2727689A1 (fr) | 1994-12-01 | 1996-06-07 | Transgene Sa | Nouveau procede de preparation d'un vecteur viral |
IL116816A (en) | 1995-01-20 | 2003-05-29 | Rhone Poulenc Rorer Sa | Cell for the production of a defective recombinant adenovirus or an adeno-associated virus and the various uses thereof |
DE19520606B4 (de) | 1995-06-06 | 2004-04-08 | Roche Diagnostics Gmbh | Vorrichtung zur optischen Untersuchung von Oberflächen |
SI0833934T2 (sl) | 1995-06-15 | 2013-04-30 | Crucell Holland B.V. | Pakirni sistemi za humani rekombinantni adenovirus za uporabo v genski terapiji |
CA2261989C (en) | 1996-07-25 | 2008-09-30 | Therion Biologics Corporation | Recombinant pox virus for immunization against tumor-associated antigens |
FR2751879B1 (fr) | 1996-07-30 | 1998-10-30 | Transgene Sa | Composition pharmaceutique contre les tumeurs et infections a papillomavirus |
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-
2010
- 2010-04-12 SG SG2011072360A patent/SG175060A1/en unknown
- 2010-04-12 SI SI201030533T patent/SI2419728T1/sl unknown
- 2010-04-12 ES ES10719285.8T patent/ES2445146T3/es active Active
- 2010-04-12 MX MX2011010920A patent/MX2011010920A/es active IP Right Grant
- 2010-04-12 US US13/264,946 patent/US20120058493A1/en not_active Abandoned
- 2010-04-12 JP JP2012505138A patent/JP5661738B2/ja not_active Expired - Fee Related
- 2010-04-12 PT PT107192858T patent/PT2419728E/pt unknown
- 2010-04-12 AU AU2010237215A patent/AU2010237215B2/en not_active Ceased
- 2010-04-12 CA CA2759050A patent/CA2759050A1/en not_active Abandoned
- 2010-04-12 RU RU2011146419/15A patent/RU2555340C2/ru not_active IP Right Cessation
- 2010-04-12 DK DK10719285.8T patent/DK2419728T3/da active
- 2010-04-12 WO PCT/EP2010/054743 patent/WO2010119003A1/en active Application Filing
- 2010-04-12 BR BRPI1010512A patent/BRPI1010512A2/pt not_active IP Right Cessation
- 2010-04-12 NZ NZ594896A patent/NZ594896A/xx not_active IP Right Cessation
- 2010-04-12 PL PL10719285T patent/PL2419728T3/pl unknown
- 2010-04-12 CN CN201080016800.2A patent/CN102395883B/zh not_active Expired - Fee Related
- 2010-04-12 KR KR1020117024190A patent/KR20120027146A/ko active IP Right Grant
- 2010-04-12 EP EP10719285.8A patent/EP2419728B1/en not_active Not-in-force
- 2010-04-16 TW TW099112032A patent/TWI426270B/zh not_active IP Right Cessation
-
2011
- 2011-09-01 IL IL214917A patent/IL214917A/en not_active IP Right Cessation
- 2011-09-29 CR CR20110513A patent/CR20110513A/es unknown
- 2011-10-14 ZA ZA2011/07545A patent/ZA201107545B/en unknown
- 2011-10-14 CO CO11136970A patent/CO6440591A2/es not_active Application Discontinuation
-
2012
- 2012-03-14 HK HK12102541.6A patent/HK1163246A1/xx not_active IP Right Cessation
-
2014
- 2014-01-08 US US14/150,503 patent/US20140141039A1/en not_active Abandoned
- 2014-02-13 CY CY20141100110T patent/CY1114910T1/el unknown
- 2014-03-20 HR HRP20140262AT patent/HRP20140262T1/hr unknown
- 2014-04-03 SM SM201400046T patent/SMT201400046B/xx unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] | ||
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |