BRPI1008538A2 - profármacos do tipo amidina, guanidina e/ou amino-hidrazona n-hidroxiladas para aplicação sobre a pele - Google Patents

profármacos do tipo amidina, guanidina e/ou amino-hidrazona n-hidroxiladas para aplicação sobre a pele

Info

Publication number
BRPI1008538A2
BRPI1008538A2 BRPI1008538A BRPI1008538A BRPI1008538A2 BR PI1008538 A2 BRPI1008538 A2 BR PI1008538A2 BR PI1008538 A BRPI1008538 A BR PI1008538A BR PI1008538 A BRPI1008538 A BR PI1008538A BR PI1008538 A2 BRPI1008538 A2 BR PI1008538A2
Authority
BR
Brazil
Prior art keywords
aminohydrazone
prodrugs
guanidine
skin application
amidine
Prior art date
Application number
BRPI1008538A
Other languages
English (en)
Inventor
Andreas Koch
Bodo Asmussen
Hans-Rainer Hoffmann
Rudolf Matusch
Original Assignee
Lohmann Therapie Syst Lts
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lohmann Therapie Syst Lts filed Critical Lohmann Therapie Syst Lts
Publication of BRPI1008538A2 publication Critical patent/BRPI1008538A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4245—Oxadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
BRPI1008538A 2009-02-10 2010-02-05 profármacos do tipo amidina, guanidina e/ou amino-hidrazona n-hidroxiladas para aplicação sobre a pele BRPI1008538A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102009008256A DE102009008256A1 (de) 2009-02-10 2009-02-10 Prodrugs vom Typ N-hydroxylierter Amidine, Guanidine und/oder Aminohydrazone zur Applikation über die Haut
PCT/EP2010/000715 WO2010091822A2 (de) 2009-02-10 2010-02-05 Prodrugs vom typ n-hydroxylierter amidine, guanidine und/oder aminohydrazone zur applikation über die haut

Publications (1)

Publication Number Publication Date
BRPI1008538A2 true BRPI1008538A2 (pt) 2016-03-15

Family

ID=42173971

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI1008538A BRPI1008538A2 (pt) 2009-02-10 2010-02-05 profármacos do tipo amidina, guanidina e/ou amino-hidrazona n-hidroxiladas para aplicação sobre a pele

Country Status (8)

Country Link
US (1) US20110311593A1 (pt)
EP (1) EP2395971A2 (pt)
JP (1) JP2012517404A (pt)
KR (1) KR20110120282A (pt)
CN (1) CN102497852A (pt)
BR (1) BRPI1008538A2 (pt)
DE (1) DE102009008256A1 (pt)
WO (1) WO2010091822A2 (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102011117128A1 (de) * 2011-10-28 2013-05-02 Christian-Albrechts-Universität Zu Kiel Verbindungen zur Therapie der Influenza
CN106361728B (zh) * 2015-07-22 2021-03-26 广东东阳光药业有限公司 经皮吸收制剂及制备经皮吸收制剂的方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5230897A (en) * 1991-10-31 1993-07-27 G. D. Searle & Co. Transdermal pentamidine
DE4321444A1 (de) 1993-06-28 1995-01-05 Bernd Prof Dr Clement Pharmazeutische Zubereitung
TW541316B (en) 1995-12-21 2003-07-11 Astrazeneca Ab Prodrugs of thrombin inhibitors
GB9614098D0 (en) * 1996-07-05 1996-09-04 Orion Yhtymae Oy Transdermal delivery of levosimendan
AU3104301A (en) * 2000-01-20 2001-07-31 Noven Pharmaceuticals, Inc. Compositions and methods to effect the release profile in the transdermal administration of active agents
US7041685B2 (en) * 2001-06-08 2006-05-09 Cytovia, Inc. Substituted 3-aryl-5-aryl-[1,2,4]-oxadiazoles and analogs as activators of caspases and inducers of apoptosis and the use thereof
AU2002350207A1 (en) * 2001-11-19 2003-06-10 Control Delivery Systems, Inc. Topical delivery of codrugs
US20030149406A1 (en) * 2002-02-07 2003-08-07 Lucie Martineau Multi-layer dressing as medical drug delivery system
US20070269379A1 (en) * 2003-07-23 2007-11-22 Samir Mitragotri Penetration Enhancer Combinations for Transdermal Delivery
ES2596809T3 (es) * 2004-10-08 2017-01-12 Noven Pharmaceuticals, Inc. Dispositivo de administración transdérmica de fármacos que incluye un refuerzo oclusivo
DE102004062614B4 (de) * 2004-12-24 2011-12-29 Lts Lohmann Therapie-Systeme Ag Transdermales therapeutisches System mit aktivierbarer Übersättigung und kontrollierter Permeationförderung sowie Verfahren zu dessen Herstellung
GB0625648D0 (en) * 2006-12-21 2007-01-31 Glaxo Group Ltd Compounds

Also Published As

Publication number Publication date
WO2010091822A3 (de) 2011-10-13
WO2010091822A2 (de) 2010-08-19
KR20110120282A (ko) 2011-11-03
DE102009008256A1 (de) 2010-08-12
WO2010091822A8 (de) 2011-08-11
US20110311593A1 (en) 2011-12-22
JP2012517404A (ja) 2012-08-02
CN102497852A (zh) 2012-06-13
EP2395971A2 (de) 2011-12-21

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE AS 5A E 6A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2383 DE 06-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.

B15K Others concerning applications: alteration of classification

Ipc: A61K 9/00 (2006.01)