BRPI0918718A2 - síntese de acetato de glatirâmero - Google Patents
síntese de acetato de glatirâmeroInfo
- Publication number
- BRPI0918718A2 BRPI0918718A2 BRPI0918718A BRPI0918718A BRPI0918718A2 BR PI0918718 A2 BRPI0918718 A2 BR PI0918718A2 BR PI0918718 A BRPI0918718 A BR PI0918718A BR PI0918718 A BRPI0918718 A BR PI0918718A BR PI0918718 A2 BRPI0918718 A2 BR PI0918718A2
- Authority
- BR
- Brazil
- Prior art keywords
- glatiramer acetate
- acetate synthesis
- synthesis
- glatiramer
- acetate
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/02—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
- C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
- C07K1/064—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for omega-amino or -guanidino functions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Water Supply & Treatment (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Polyamides (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18821608P | 2008-08-07 | 2008-08-07 | |
| PCT/US2009/052845 WO2010017292A1 (en) | 2008-08-07 | 2009-08-05 | Synthesis of glatiramer acetate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0918718A2 true BRPI0918718A2 (pt) | 2015-12-01 |
Family
ID=41653533
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0918718A BRPI0918718A2 (pt) | 2008-08-07 | 2009-08-05 | síntese de acetato de glatirâmero |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US8212002B2 (pt) |
| EP (1) | EP2326657B1 (pt) |
| JP (1) | JP2011530523A (pt) |
| KR (1) | KR20110059606A (pt) |
| CN (1) | CN102112485B (pt) |
| AR (1) | AR072974A1 (pt) |
| AU (1) | AU2009279636A1 (pt) |
| BR (1) | BRPI0918718A2 (pt) |
| CA (1) | CA2733500A1 (pt) |
| IL (1) | IL211052A (pt) |
| NZ (1) | NZ590872A (pt) |
| WO (1) | WO2010017292A1 (pt) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009129018A1 (en) | 2008-04-16 | 2009-10-22 | Momenta Pharmaceuticals, Inc. | Analysis of amino acid copolymer compositions |
| ES2537022T3 (es) * | 2008-08-07 | 2015-06-01 | Sigma-Aldrich Co. Llc | Preparación de polilisina y poliornitina de bajo peso molecular con alto rendimiento |
| US8859489B2 (en) | 2009-04-03 | 2014-10-14 | Momenta Pharmaceuticals, Inc. | Water-mediated control of depolymerization step of glatiramer acetate synthesis |
| WO2012114167A1 (en) * | 2011-02-24 | 2012-08-30 | Biocon Limited | Processes for the preparation of glatiramer acetate |
| GB2478837A (en) * | 2011-03-14 | 2011-09-21 | Cipla Ltd | Preparation of glatiramer |
| WO2013009864A1 (en) | 2011-07-11 | 2013-01-17 | Momenta Pharmaceuticals, Inc. | Structure assessment of heterogeneous polypeptide mixtures |
| WO2013009885A2 (en) | 2011-07-11 | 2013-01-17 | Momenta Pharmaceuticals, Inc. | Evaluation of copolymer diethylamide |
| US8575198B1 (en) | 2011-09-07 | 2013-11-05 | Momenta Pharmaceuticals, Inc. | In-process control for the manufacture of glatiramer acetate |
| CN104844697B (zh) * | 2014-09-26 | 2018-10-23 | 深圳翰宇药业股份有限公司 | 醋酸格拉替雷的制备方法 |
| CN105884866B (zh) * | 2015-01-26 | 2021-04-20 | 漳州未名博欣生物医药有限公司 | 格拉替雷的化学合成方法 |
| US10323289B2 (en) | 2017-06-26 | 2019-06-18 | Institut Pasteur | Treatments to eliminate HIV reservoirs and reduce viral load |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL36670A (en) | 1971-04-21 | 1974-09-10 | Sela M | Therapeutic basic copolymers of amino acids |
| US5800808A (en) | 1994-05-24 | 1998-09-01 | Veda Research And Development Co., Ltd. | Copolymer-1 improvements in compositions of copolymers |
| US6013764A (en) | 1996-07-17 | 2000-01-11 | Ortho Pharmaceutical Corp. | Liquid phase peptide synthesis of KL-4 pulmonary surfactant |
| SI1797109T1 (sl) * | 2004-09-09 | 2016-07-29 | Yeda Research And Development Co., Ltd. | Zmesi polipeptidov, sestavki, ki jih vsebujejo, in postopki za njihovo pripravo ter njihove uporabe |
| NZ554018A (en) * | 2004-09-09 | 2009-06-26 | Teva Pharma | Process for preparation of trifluoroacetyl glatiramer acetate using purified hydrobromic acid |
| CA2583589C (en) * | 2004-10-29 | 2012-04-24 | Sandoz Ag | Processes for preparing glatiramer |
| WO2006083608A1 (en) | 2005-02-02 | 2006-08-10 | Teva Pharmaceutical Industries, Ltd. | Process for producing polypeptide mixtures using hydrogenolysis |
| JP2009504885A (ja) | 2005-08-15 | 2009-02-05 | チャン，ウェイ，ホン | コポリマー−１の製造方法 |
| US20090035816A1 (en) | 2007-08-02 | 2009-02-05 | Scinopharm Taiwan Ltd. | Process for the preparation of a polypeptide |
| CA2761406C (en) * | 2009-05-08 | 2017-12-19 | Scinopharm Taiwan, Ltd. | Methods of analyzing peptide mixtures |
-
2009
- 2009-08-05 BR BRPI0918718A patent/BRPI0918718A2/pt not_active Application Discontinuation
- 2009-08-05 JP JP2011522216A patent/JP2011530523A/ja active Pending
- 2009-08-05 CN CN2009801308021A patent/CN102112485B/zh not_active Expired - Fee Related
- 2009-08-05 KR KR1020117005133A patent/KR20110059606A/ko not_active Application Discontinuation
- 2009-08-05 US US12/536,023 patent/US8212002B2/en not_active Expired - Fee Related
- 2009-08-05 NZ NZ590872A patent/NZ590872A/xx not_active IP Right Cessation
- 2009-08-05 CA CA2733500A patent/CA2733500A1/en not_active Abandoned
- 2009-08-05 EP EP09805500.7A patent/EP2326657B1/en not_active Not-in-force
- 2009-08-05 WO PCT/US2009/052845 patent/WO2010017292A1/en active Application Filing
- 2009-08-05 AU AU2009279636A patent/AU2009279636A1/en not_active Abandoned
- 2009-08-06 AR ARP090103027A patent/AR072974A1/es unknown
-
2011
- 2011-02-03 IL IL211052A patent/IL211052A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| JP2011530523A (ja) | 2011-12-22 |
| EP2326657A1 (en) | 2011-06-01 |
| AU2009279636A1 (en) | 2010-02-11 |
| IL211052A (en) | 2016-05-31 |
| US8212002B2 (en) | 2012-07-03 |
| CN102112485A (zh) | 2011-06-29 |
| WO2010017292A1 (en) | 2010-02-11 |
| AR072974A1 (es) | 2010-10-06 |
| EP2326657B1 (en) | 2017-09-27 |
| IL211052A0 (en) | 2011-04-28 |
| US20100036092A1 (en) | 2010-02-11 |
| NZ590872A (en) | 2012-10-26 |
| CN102112485B (zh) | 2013-11-27 |
| CA2733500A1 (en) | 2010-02-11 |
| EP2326657A4 (en) | 2012-10-31 |
| KR20110059606A (ko) | 2011-06-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
| B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |