BRPI0909817A2 - uso de células-tronco mesenquimais para tratamento de doenças e distúrbios genéticos - Google Patents
uso de células-tronco mesenquimais para tratamento de doenças e distúrbios genéticosInfo
- Publication number
- BRPI0909817A2 BRPI0909817A2 BRPI0909817A BRPI0909817A BRPI0909817A2 BR PI0909817 A2 BRPI0909817 A2 BR PI0909817A2 BR PI0909817 A BRPI0909817 A BR PI0909817A BR PI0909817 A BRPI0909817 A BR PI0909817A BR PI0909817 A2 BRPI0909817 A2 BR PI0909817A2
- Authority
- BR
- Brazil
- Prior art keywords
- disorders
- stem cells
- mesenchymal stem
- treat genetic
- genetic disorders
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0652—Cells of skeletal and connective tissues; Mesenchyme
- C12N5/0662—Stem cells
- C12N5/0663—Bone marrow mesenchymal stem cells (BM-MSC)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Genetics & Genomics (AREA)
- Neurology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Developmental Biology & Embryology (AREA)
- Hematology (AREA)
- Wood Science & Technology (AREA)
- Cell Biology (AREA)
- General Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Psychology (AREA)
- Obesity (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12/042,487 US20080286249A1 (en) | 2006-01-12 | 2008-03-05 | Use of mesenchymal stem cells for treating genetic diseases and disorders |
PCT/US2009/001390 WO2009111030A1 (en) | 2008-03-05 | 2009-03-04 | Use of mesenchymal stem cells for treating genetic diseases and disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0909817A2 true BRPI0909817A2 (pt) | 2017-06-13 |
Family
ID=40635808
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0909817A BRPI0909817A2 (pt) | 2008-03-05 | 2009-03-04 | uso de células-tronco mesenquimais para tratamento de doenças e distúrbios genéticos |
Country Status (10)
Country | Link |
---|---|
US (8) | US20080286249A1 (pt) |
EP (1) | EP2262513A1 (pt) |
JP (1) | JP6037597B2 (pt) |
CN (1) | CN102014936A (pt) |
AU (1) | AU2009220137A1 (pt) |
BR (1) | BRPI0909817A2 (pt) |
CA (1) | CA2717498A1 (pt) |
MX (1) | MX2010009767A (pt) |
NZ (1) | NZ587809A (pt) |
WO (1) | WO2009111030A1 (pt) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103060263B (zh) | 2005-12-29 | 2016-03-16 | 人类起源公司 | 胎盘干细胞群 |
CN105766891A (zh) | 2008-08-20 | 2016-07-20 | 人类起源公司 | 改进的细胞组合物及制备所述组合物的方法 |
MX2011001992A (es) | 2008-08-22 | 2011-03-29 | Anthrogenesis Corp | Metodos y composiciones para el tratamiento de defectos oseos con poblaciones de celulas placentarias. |
AU2009288781B2 (en) | 2008-09-02 | 2015-01-29 | Pluri Biotech Ltd | Adherent cells from placenta tissue and use thereof in therapy |
JP5869342B2 (ja) | 2008-11-19 | 2016-02-24 | アンスロジェネシス コーポレーション | 羊膜由来接着細胞 |
NZ599407A (en) * | 2009-11-27 | 2014-09-26 | Stempeutics Res Pvt Ltd | Methods of preparing mesenchymal stem cells, compositions and kit thereof |
US20110142805A1 (en) * | 2009-12-15 | 2011-06-16 | Advanced Technologies And Regenerative Medicine, Llc | Method of renal repair and regeneration and the treatment of diabetic nephropathy |
WO2011127113A1 (en) | 2010-04-08 | 2011-10-13 | Anthrogenesis Corporation | Treatment of sarcoidosis using placental stem cells |
AR093183A1 (es) | 2010-12-31 | 2015-05-27 | Anthrogenesis Corp | Aumento de la potencia de celulas madre de placenta usando moleculas de arn moduladoras |
EP3260533B1 (en) * | 2011-03-22 | 2019-09-11 | Pluristem Ltd. | Methods for treating radiation or chemical injury |
MX357749B (es) | 2011-06-01 | 2018-07-23 | Anthrogenesis Corp | Tratamiento contra el dolor utilizando células madre placentarias. |
US9925221B2 (en) * | 2011-09-09 | 2018-03-27 | Celularity, Inc. | Treatment of amyotrophic lateral sclerosis using placental stem cells |
CN103183736A (zh) * | 2011-12-27 | 2013-07-03 | 北京和信非凡生物技术有限公司 | 一种抗clcn7蛋白的单克隆抗体及其应用 |
EP2892577B1 (en) * | 2012-09-04 | 2019-01-30 | Anthrogenesis Corporation | Methods of tissue generation |
WO2014087658A1 (en) * | 2012-12-07 | 2014-06-12 | Kuraray Co., Ltd. | Method of cell fusion and fusion cells |
US20140271568A1 (en) | 2013-03-12 | 2014-09-18 | Hawking Biological Technology Co., Ltd | Method and kit for providing an increased expression of telomerase, brain-derived neurotrophic factor, stromal cell-derived factor-1, cxc chemokine receptor 4, and/or immune regulatory factor of stem cell |
CN104042606B (zh) * | 2013-03-12 | 2017-05-24 | 国钦生物科技股份有限公司 | 苯酞化合物的应用 |
WO2015187994A1 (en) * | 2014-06-04 | 2015-12-10 | Cedars-Sinai Medical Center | Method for non surgical repair of vertebral compression fractures |
CN104726496B (zh) * | 2015-03-27 | 2017-07-07 | 中国科学院生物物理研究所 | 携带人类成年早衰症基因突变的多能干细胞及制备方法 |
CN107920503A (zh) | 2015-06-11 | 2018-04-17 | 伊利诺伊大学理事会 | 肌营养不良症嵌合细胞和治疗肌营养不良症的方法 |
US10463767B2 (en) | 2016-04-22 | 2019-11-05 | Vivex Biologics Group, Inc. | Moldable bone composition |
US11253630B2 (en) | 2016-04-22 | 2022-02-22 | Vivex Biologics Group, Inc. | Malleable demineralized bone composition and method of manufacture |
US9788950B1 (en) | 2016-04-22 | 2017-10-17 | Vivex Biomedical, Inc. | Cohesive bone composition |
US10596298B2 (en) | 2016-04-22 | 2020-03-24 | Vivex Biologics Group, Inc. | Malleable demineralized bone composition and method of manufacture |
US11253629B2 (en) | 2016-04-22 | 2022-02-22 | Vivex Biologics Group, Inc. | Bone gel sheet composition and method of manufacture |
EP3543331A4 (en) | 2016-11-15 | 2020-07-01 | Kaneka Corporation | CELL POPULATION WITH MESENCHYMAL STEM CELLS FROM FETAL ATTACHMENTS, METHOD FOR THE PRODUCTION THEREOF AND MEDICAL COMPOSITION |
CN111406106A (zh) * | 2017-11-28 | 2020-07-10 | 伊利诺伊大学理事会 | 多嵌合细胞以及移植疗法与免疫缺陷和遗传病症的治疗 |
JP7454379B2 (ja) | 2017-12-28 | 2024-03-22 | 株式会社カネカ | 接着性幹細胞を含む細胞集団とその製造方法、及び医薬組成物 |
CN113993527A (zh) | 2019-06-14 | 2022-01-28 | 株式会社钟化 | 包含间充质细胞的细胞群、包含其的医药组合物及其制造方法 |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6010696A (en) * | 1990-11-16 | 2000-01-04 | Osiris Therapeutics, Inc. | Enhancing hematopoietic progenitor cell engraftment using mesenchymal stem cells |
US5486359A (en) * | 1990-11-16 | 1996-01-23 | Osiris Therapeutics, Inc. | Human mesenchymal stem cells |
US5733542A (en) * | 1990-11-16 | 1998-03-31 | Haynesworth; Stephen E. | Enhancing bone marrow engraftment using MSCS |
US5635156A (en) * | 1993-09-13 | 1997-06-03 | University Of Pittsburgh | Non-lethal methods for conditioning a recipient for bone marrow transplantation |
US5591625A (en) * | 1993-11-24 | 1997-01-07 | Case Western Reserve University | Transduced mesenchymal stem cells |
US6653134B2 (en) * | 1995-03-28 | 2003-11-25 | Cp Hahnemann University | Isolated stromal cells for use in the treatment of diseases of the central nervous system |
US6974571B2 (en) * | 1995-03-28 | 2005-12-13 | Thomas Jefferson University | Isolated stromal cells and methods of using the same |
US6962698B1 (en) * | 1998-02-17 | 2005-11-08 | Gamida Cell Ltd. | Methods of controlling proliferation and differentiation of stem and progenitor cells |
EP1062321B1 (en) * | 1998-03-13 | 2004-12-29 | Osiris Therapeutics, Inc. | Uses for humane non-autologous mesenchymal stem cells |
DK1066052T3 (da) * | 1998-03-18 | 2006-06-12 | Osiris Therapeutics Inc | Mesenchymstamceller til forebyggelse og behandling af immunreaktioner ved transplantationer |
US7544509B2 (en) * | 2000-01-24 | 2009-06-09 | Mcgill University | Method for preparing stem cell preparations |
EP1424389A4 (en) * | 2001-08-07 | 2004-08-25 | Kirin Brewery | PROCESS FOR THE PREPARATION OF MULTIPOTENT HEMATOPOIETIC STEM CELLS |
CA2460985C (en) * | 2001-09-20 | 2016-01-05 | Anticancer, Inc. | Nestin-expressing hair follicle stem cells |
US20050048036A1 (en) * | 2001-12-07 | 2005-03-03 | Hedrick Marc H. | Methods of using regenerative cells in the treatment of inherited and acquired disorders of the bone, bone marrow, liver, and other tissues |
US20030157110A1 (en) * | 2002-01-07 | 2003-08-21 | Millennium Pharmaceuticals, Inc. | Methods for the treatment of metabolic disorders, including obesity and diabetes |
DE60326001D1 (de) * | 2002-02-22 | 2009-03-12 | Intracel Recources Llc | Sterile immunogene nicht-tumorigene tumorzell-zusammensetzungen und verfahren |
US20050058641A1 (en) * | 2002-05-22 | 2005-03-17 | Siemionow Maria Z. | Tolerance induction and maintenance in hematopoietic stem cell allografts |
DE10242337A1 (de) * | 2002-09-09 | 2004-03-18 | Eberhard-Karls-Universität Tübingen Universitätsklinikum | Antikörper zur Isolierung und/oder Identifizierung neuronaler Stammzellen und Verfahren zur Isolierung und/oder Identifizierung neuronaler Vorläuferzellen |
GB0304030D0 (en) * | 2003-02-21 | 2003-03-26 | King S College London | Teeth |
JP2007535486A (ja) * | 2003-05-07 | 2007-12-06 | ラ ホーヤ インスティチュート フォー モレキュラー メディシン | 高分子量のヒアルロン酸を用いた内因性又は埋め込まれた又は移植された幹細胞の機能回復を促進するための方法 |
US20050019801A1 (en) * | 2003-06-04 | 2005-01-27 | Curis, Inc. | Stem cell-based methods for identifying and characterizing agents |
AU2004252570C1 (en) * | 2003-06-27 | 2012-03-01 | Ethicon, Incorporated | Soft tissue repair and regeneration using postpartum-derived cells |
US20050256077A1 (en) * | 2004-03-30 | 2005-11-17 | Henning Susan J | Gastrointestinal stem cells and uses thereof |
US20070253931A1 (en) * | 2006-01-12 | 2007-11-01 | Osiris Therapeutics, Inc. | Use of mesenchymal stem cells for treating genetic diseases and disorders |
-
2008
- 2008-03-05 US US12/042,487 patent/US20080286249A1/en not_active Abandoned
-
2009
- 2009-03-04 CN CN2009801155331A patent/CN102014936A/zh active Pending
- 2009-03-04 MX MX2010009767A patent/MX2010009767A/es active IP Right Grant
- 2009-03-04 NZ NZ587809A patent/NZ587809A/xx not_active IP Right Cessation
- 2009-03-04 EP EP09717978A patent/EP2262513A1/en not_active Withdrawn
- 2009-03-04 AU AU2009220137A patent/AU2009220137A1/en not_active Abandoned
- 2009-03-04 WO PCT/US2009/001390 patent/WO2009111030A1/en active Application Filing
- 2009-03-04 JP JP2010549663A patent/JP6037597B2/ja not_active Expired - Fee Related
- 2009-03-04 CA CA2717498A patent/CA2717498A1/en not_active Abandoned
- 2009-03-04 BR BRPI0909817A patent/BRPI0909817A2/pt not_active IP Right Cessation
-
2010
- 2010-07-28 US US12/845,191 patent/US20100291047A1/en not_active Abandoned
- 2010-09-02 US US12/874,796 patent/US20100330052A1/en not_active Abandoned
-
2011
- 2011-03-31 US US13/077,004 patent/US20110177045A1/en not_active Abandoned
-
2012
- 2012-06-29 US US13/538,198 patent/US20120263687A1/en not_active Abandoned
-
2013
- 2013-01-03 US US13/733,550 patent/US20130121975A1/en not_active Abandoned
- 2013-07-26 US US13/951,685 patent/US20140030235A1/en not_active Abandoned
-
2014
- 2014-07-14 US US14/330,084 patent/US20140322180A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
JP2011514901A (ja) | 2011-05-12 |
US20140030235A1 (en) | 2014-01-30 |
US20100330052A1 (en) | 2010-12-30 |
US20140322180A1 (en) | 2014-10-30 |
NZ587809A (en) | 2012-08-31 |
CA2717498A1 (en) | 2009-09-11 |
CN102014936A (zh) | 2011-04-13 |
US20130121975A1 (en) | 2013-05-16 |
WO2009111030A1 (en) | 2009-09-11 |
US20120263687A1 (en) | 2012-10-18 |
MX2010009767A (es) | 2010-09-28 |
JP6037597B2 (ja) | 2016-12-07 |
EP2262513A1 (en) | 2010-12-22 |
US20080286249A1 (en) | 2008-11-20 |
AU2009220137A1 (en) | 2009-09-11 |
US20100291047A1 (en) | 2010-11-18 |
US20110177045A1 (en) | 2011-07-21 |
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Owner name: OSIRIS THERAPEUTICS (US) Free format text: INDEFERIDO O PEDIDO DE TRANSFERENCIA CONTIDO NA PETICAO 860140039720 DE 27/03/2014 EM VIRTUDE DO DESPACHO PUBLICADO NA RPI NO 2468 DE 24/04/2018. Owner name: OSIRIS THERAPEUTICS (US) |