BRPI0906044A2 - "mutante solúvel tnfrp75, proteína de fusão, sequências de dna, usos do mutante solúvel tnfrp75 e da proteína de fusão e composições farmacêuticas" - Google Patents

"mutante solúvel tnfrp75, proteína de fusão, sequências de dna, usos do mutante solúvel tnfrp75 e da proteína de fusão e composições farmacêuticas"

Info

Publication number
BRPI0906044A2
BRPI0906044A2 BRPI0906044-8A BRPI0906044A BRPI0906044A2 BR PI0906044 A2 BRPI0906044 A2 BR PI0906044A2 BR PI0906044 A BRPI0906044 A BR PI0906044A BR PI0906044 A2 BRPI0906044 A2 BR PI0906044A2
Authority
BR
Brazil
Prior art keywords
tnfrp75
fusion protein
soluble mutant
pharmaceutical compositions
dna sequences
Prior art date
Application number
BRPI0906044-8A
Other languages
English (en)
Inventor
Yanjun Liu
Fang Wu
Jinsong Wu
Tong Yang
Yijun Shen
Original Assignee
Shanghai Fudan Zhangjiang Bio Pharmaceutical Co Ltd
Taizhou Fudan Zhangjiang Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shanghai Fudan Zhangjiang Bio Pharmaceutical Co Ltd, Taizhou Fudan Zhangjiang Pharmaceutical Co Ltd filed Critical Shanghai Fudan Zhangjiang Bio Pharmaceutical Co Ltd
Publication of BRPI0906044A2 publication Critical patent/BRPI0906044A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7151—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for tumor necrosis factor [TNF], for lymphotoxin [LT]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BRPI0906044-8A 2008-05-30 2009-01-12 "mutante solúvel tnfrp75, proteína de fusão, sequências de dna, usos do mutante solúvel tnfrp75 e da proteína de fusão e composições farmacêuticas" BRPI0906044A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CNA200810038410XA CN101591388A (zh) 2008-05-30 2008-05-30 一种可溶性tnf受体突变体
PCT/CN2009/000037 WO2009143689A1 (zh) 2008-05-30 2009-01-12 一种可溶性tnf受体突变体

Publications (1)

Publication Number Publication Date
BRPI0906044A2 true BRPI0906044A2 (pt) 2015-07-07

Family

ID=41376564

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0906044-8A BRPI0906044A2 (pt) 2008-05-30 2009-01-12 "mutante solúvel tnfrp75, proteína de fusão, sequências de dna, usos do mutante solúvel tnfrp75 e da proteína de fusão e composições farmacêuticas"

Country Status (10)

Country Link
US (1) US8454969B2 (pt)
EP (1) EP2221314B1 (pt)
JP (1) JP5445975B2 (pt)
KR (1) KR101243951B1 (pt)
CN (2) CN101591388A (pt)
AU (1) AU2009253623B2 (pt)
BR (1) BRPI0906044A2 (pt)
CA (1) CA2710040C (pt)
RU (1) RU2478645C2 (pt)
WO (1) WO2009143689A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101273893B1 (ko) * 2010-09-13 2013-06-14 한올바이오파마주식회사 변형된 인간 종양 괴사 인자 수용체-1 폴리펩티드 또는 그의 절편 및 그의 제조방법
US8754037B2 (en) 2010-12-23 2014-06-17 Hanall Biopharma Co., Ltd. Modified human tumor necrosis factor receptor-1 polypeptide or fragment thereof, and method for preparing same
KR101514238B1 (ko) * 2012-06-21 2015-04-28 한올바이오파마주식회사 변형된 인간 종양 괴사 인자 수용체-1 폴리펩티드의 신규 용도
CN104561022B (zh) * 2014-12-22 2017-05-17 南京师范大学 家猪肿瘤坏死因子突变体的构建及蛋白表达纯化方法
CN108853482A (zh) * 2017-05-12 2018-11-23 上海复旦张江生物医药股份有限公司 一种重组人TNFR-Fc融合蛋白突变体的用途
TW202229355A (zh) * 2020-12-11 2022-08-01 大陸商杭州阿諾生物醫藥科技有限公司 抗ｔｎｆｒ２抗體及其應用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2288351A1 (en) * 1997-05-01 1998-11-05 Amgen Inc. Chimeric opg polypeptides
IL130608A0 (en) * 1999-06-23 2000-06-01 Compugen Ltd Novel nucleic and amino acid sequence
CN1246337C (zh) * 2002-11-26 2006-03-22 广州绿阳生物工程有限公司 新型TNFR－Fc融合蛋白
US7276477B2 (en) * 2003-08-01 2007-10-02 Amgen Inc. Crystals of etanercept and methods of making thereof
CN101085813B (zh) * 2006-06-05 2012-01-25 上海复旦张江生物医药股份有限公司 一种可溶性tnf受体突变体
CN101003575A (zh) * 2007-01-12 2007-07-25 中国医学科学院血液学研究所泰达生命科学技术研究中心 人肿瘤坏死因子可溶性受体Ⅱ－抗体Fc段融合蛋白

Also Published As

Publication number Publication date
US8454969B2 (en) 2013-06-04
CN101883787A (zh) 2010-11-10
EP2221314A4 (en) 2010-12-29
RU2010141916A (ru) 2012-04-20
KR20100135706A (ko) 2010-12-27
JP5445975B2 (ja) 2014-03-19
AU2009253623B2 (en) 2013-08-22
CN101883787B (zh) 2014-09-10
AU2009253623A1 (en) 2009-12-03
KR101243951B1 (ko) 2013-03-13
JP2011511627A (ja) 2011-04-14
RU2478645C2 (ru) 2013-04-10
US20110117082A1 (en) 2011-05-19
CA2710040A1 (en) 2009-12-03
CA2710040C (en) 2013-05-28
CN101591388A (zh) 2009-12-02
EP2221314B1 (en) 2013-07-03
EP2221314A1 (en) 2010-08-25
WO2009143689A1 (zh) 2009-12-03

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL