BRPI0821021A2 - Compostos de amida como reforçadores de antivirais - Google Patents

Compostos de amida como reforçadores de antivirais

Info

Publication number
BRPI0821021A2
BRPI0821021A2 BRPI0821021-7A BRPI0821021A BRPI0821021A2 BR PI0821021 A2 BRPI0821021 A2 BR PI0821021A2 BR PI0821021 A BRPI0821021 A BR PI0821021A BR PI0821021 A2 BRPI0821021 A2 BR PI0821021A2
Authority
BR
Brazil
Prior art keywords
amide compounds
boosters
antiviral
antiviral boosters
amide
Prior art date
Application number
BRPI0821021-7A
Other languages
English (en)
Inventor
Tim Hugo Maria Jonckers
Wim Bert Griet Schepens
Geerwin Yvonne Paul Haché
Beate Sabine Hallenberger
Jennifer Chiyomi Sasaki
Judith Eva Baumeister
Gerben Albert Eleutherous Van T Klooster
Original Assignee
Tibotec Pharm Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39386111&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0821021(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Tibotec Pharm Ltd filed Critical Tibotec Pharm Ltd
Publication of BRPI0821021A2 publication Critical patent/BRPI0821021A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Hydrogenated Pyridines (AREA)
BRPI0821021-7A 2007-12-06 2008-12-05 Compostos de amida como reforçadores de antivirais BRPI0821021A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07122468 2007-12-06
PCT/EP2008/066847 WO2009071650A2 (en) 2007-12-06 2008-12-05 Amide compounds as boosters of antivirals

Publications (1)

Publication Number Publication Date
BRPI0821021A2 true BRPI0821021A2 (pt) 2015-06-16

Family

ID=39386111

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0821021-7A BRPI0821021A2 (pt) 2007-12-06 2008-12-05 Compostos de amida como reforçadores de antivirais

Country Status (24)

Country Link
US (1) US8350048B2 (pt)
EP (1) EP2235008B1 (pt)
JP (1) JP5509092B2 (pt)
KR (1) KR101624675B1 (pt)
CN (1) CN101878210B (pt)
AP (1) AP2804A (pt)
AR (1) AR069595A1 (pt)
AU (1) AU2008333165B2 (pt)
BR (1) BRPI0821021A2 (pt)
CA (1) CA2706155C (pt)
CL (1) CL2008003639A1 (pt)
EA (1) EA019616B1 (pt)
HK (1) HK1149553A1 (pt)
IL (1) IL205489A (pt)
MX (1) MX2010006166A (pt)
MY (1) MY151005A (pt)
NZ (1) NZ585652A (pt)
PA (1) PA8806801A1 (pt)
PE (1) PE20091263A1 (pt)
TW (1) TWI438202B (pt)
UA (1) UA103013C2 (pt)
UY (1) UY31513A1 (pt)
WO (1) WO2009071650A2 (pt)
ZA (1) ZA201004025B (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0920809A2 (pt) * 2008-10-07 2016-07-12 Tibotec Pharm Ltd compostos de amida como reforcos de antivirais
US20120172368A1 (en) * 2009-09-03 2012-07-05 Koen Vandyck Bis-Benzimidazole Derivatives
US8759535B2 (en) 2010-02-18 2014-06-24 High Point Pharmaceuticals, Llc Substituted fused imidazole derivatives, pharmaceutical compositions, and methods of use thereof
MX339243B (es) 2011-02-03 2016-05-18 Vtv Therapeutics Llc Derivados fusionados sustituidos de imidazol, composiciones farmaceuticas y metodos de uso de los mismos.
AU2012245524A1 (en) * 2011-04-22 2013-10-24 Merck Sharp & Dohme Corp. Taste-masked formulations of raltegravir
WO2014194519A1 (en) 2013-06-07 2014-12-11 Merck Sharp & Dohme Corp. Imidazole derivatives and methods of use thereof for improving pharmacokinetics of drug
CN104000824B (zh) * 2014-05-28 2016-07-06 中山大学 苯并五元杂环类化合物在制备抗hiv-1病毒药物中的应用
WO2016089648A1 (en) 2014-12-01 2016-06-09 Vtv Therapeutics Llc Bach 1 inhibitors in combination with nrf2 activators and pharmaceutical compositions thereof
CN105985356B (zh) * 2015-02-05 2018-06-22 四川大学 咪唑[2,1-b]噻唑衍生物及其制备方法和用途
ES2893099T3 (es) 2015-12-22 2022-02-08 Kancera Ab Acidos hidroxámicos bicíclicos útiles como inhibidores de la actividad de histona desacetilasa de mamíferos
AR114136A1 (es) 2017-10-10 2020-07-29 Hoffmann La Roche Compuestos heterocíclicos

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6037157A (en) * 1995-06-29 2000-03-14 Abbott Laboratories Method for improving pharmacokinetics
AR037797A1 (es) 2001-12-12 2004-12-01 Tibotec Pharm Ltd Combinacion de inhibidores de proteasa dependientes del citocromo p450
MY142238A (en) * 2002-03-12 2010-11-15 Tibotec Pharm Ltd Broadspectrum substituted benzimidazole sulfonamide hiv protease inhibitors
JP4879484B2 (ja) * 2002-08-02 2012-02-22 テイボテク・フアーマシユーチカルズ・リミテツド 広スペクトルの２−アミノ−ベンゾチアゾールスルホンアミドｈｉｖプロテアーゼ阻害剤
AR053845A1 (es) * 2005-04-15 2007-05-23 Tibotec Pharm Ltd 5-tiazolilmetil[(1s,2r)-3-[[(2-amino-6-benzoxazolil)sulfonil)](2-metilpropil)amino]-2-hidroxi-1-(fenilmetil)propil]carbamato como mejorador de farmacos metabolizados por el citocromo p450
CN101674822A (zh) 2006-08-18 2010-03-17 塞阔伊亚药品公司 抑制细胞色素p450的组合物和方法

Also Published As

Publication number Publication date
AP2804A (en) 2013-11-30
IL205489A0 (en) 2010-12-30
CA2706155C (en) 2016-07-19
JP5509092B2 (ja) 2014-06-04
PE20091263A1 (es) 2009-08-14
KR101624675B1 (ko) 2016-05-27
EA019616B1 (ru) 2014-05-30
EP2235008A2 (en) 2010-10-06
ZA201004025B (en) 2011-12-28
EA201070691A1 (ru) 2010-10-29
HK1149553A1 (en) 2011-10-07
WO2009071650A2 (en) 2009-06-11
JP2011506291A (ja) 2011-03-03
KR20100092489A (ko) 2010-08-20
MX2010006166A (es) 2010-10-05
WO2009071650A3 (en) 2009-09-11
AU2008333165B2 (en) 2013-04-11
NZ585652A (en) 2011-10-28
AR069595A1 (es) 2010-02-03
UY31513A1 (es) 2009-07-17
PA8806801A1 (es) 2009-07-23
AP2010005285A0 (en) 2010-06-30
IL205489A (en) 2016-09-29
MY151005A (en) 2014-03-31
US8350048B2 (en) 2013-01-08
CA2706155A1 (en) 2009-06-11
CN101878210B (zh) 2013-07-17
TWI438202B (zh) 2014-05-21
UA103013C2 (uk) 2013-09-10
US20100305073A1 (en) 2010-12-02
TW200938540A (en) 2009-09-16
CN101878210A (zh) 2010-11-03
EP2235008B1 (en) 2016-03-16
CL2008003639A1 (es) 2010-01-15
AU2008333165A1 (en) 2009-06-11

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Legal Events

Date Code Title Description
B25D Requested change of name of applicant approved

Owner name: JANSSEN R AND D IRELAND (IE)

B25A Requested transfer of rights approved

Owner name: JANSSEN SCIENCES IRELAND UC (IE)

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 10A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2494 DE 23-10-2018 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.