BRPI0810444A2 - utilização da 4-ciclopropil metóxi-n-(3,5-dicloro-1-óxido-4-piridin-4-il)-5-(metóxi)piridina-2-carboxamida para o tratamento dos distúrbios motores ligados ao mal de parkinson - Google Patents

utilização da 4-ciclopropil metóxi-n-(3,5-dicloro-1-óxido-4-piridin-4-il)-5-(metóxi)piridina-2-carboxamida para o tratamento dos distúrbios motores ligados ao mal de parkinson

Info

Publication number
BRPI0810444A2
BRPI0810444A2 BRPI0810444A BRPI0810444A BRPI0810444A2 BR PI0810444 A2 BRPI0810444 A2 BR PI0810444A2 BR PI0810444 A BRPI0810444 A BR PI0810444A BR PI0810444 A BRPI0810444 A BR PI0810444A BR PI0810444 A2 BRPI0810444 A2 BR PI0810444A2
Authority
BR
Brazil
Prior art keywords
methoxy
carboxamide
pyridin
parkinson
dichloro
Prior art date
Application number
BRPI0810444A
Other languages
English (en)
Portuguese (pt)
Inventor
Christine Menet
Christine Ravinet-Trillou
Claire Delgorge
Gilles Poughon
Philippe Delay-Goyet
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of BRPI0810444A2 publication Critical patent/BRPI0810444A2/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
BRPI0810444A 2007-04-19 2008-04-16 utilização da 4-ciclopropil metóxi-n-(3,5-dicloro-1-óxido-4-piridin-4-il)-5-(metóxi)piridina-2-carboxamida para o tratamento dos distúrbios motores ligados ao mal de parkinson BRPI0810444A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0702853A FR2915100B1 (fr) 2007-04-19 2007-04-19 Utilisation du 4-cyclopropylmethoxy-n-(3,5-dichloro-1-oxydo- pyridin-4-yl)-5-(methoxy)pyridine-2-carboxalide pour le traitement des desordres moteurs lies a la maladie de parkinson
PCT/FR2008/000534 WO2008145841A1 (fr) 2007-04-19 2008-04-16 Utilisation du 4-cyclopropylmethoxy-n-(3,5-dichloro-1 -oxydo- pyridin-4-yl)-5-(methoxy)pyridine-2-carboxamide pour le traitement des desordres moteurs lies a la maladie de parkinson

Publications (1)

Publication Number Publication Date
BRPI0810444A2 true BRPI0810444A2 (pt) 2016-05-31

Family

ID=38712405

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0810444A BRPI0810444A2 (pt) 2007-04-19 2008-04-16 utilização da 4-ciclopropil metóxi-n-(3,5-dicloro-1-óxido-4-piridin-4-il)-5-(metóxi)piridina-2-carboxamida para o tratamento dos distúrbios motores ligados ao mal de parkinson

Country Status (33)

Country Link
US (1) US20100130554A1 (OSRAM)
EP (1) EP2146714B1 (OSRAM)
JP (1) JP5386478B2 (OSRAM)
KR (2) KR101503942B1 (OSRAM)
CN (1) CN101663035B (OSRAM)
AR (1) AR066108A1 (OSRAM)
AT (1) ATE513548T1 (OSRAM)
AU (1) AU2008257322B2 (OSRAM)
BR (1) BRPI0810444A2 (OSRAM)
CA (1) CA2684174C (OSRAM)
CL (1) CL2008001136A1 (OSRAM)
CY (1) CY1111840T1 (OSRAM)
DK (1) DK2146714T3 (OSRAM)
EA (1) EA019194B1 (OSRAM)
ES (1) ES2367408T3 (OSRAM)
FR (1) FR2915100B1 (OSRAM)
HR (1) HRP20110666T1 (OSRAM)
IL (1) IL201448A (OSRAM)
JO (1) JO2678B1 (OSRAM)
MA (1) MA31367B1 (OSRAM)
ME (1) ME00935B (OSRAM)
MX (1) MX2009011284A (OSRAM)
MY (1) MY148092A (OSRAM)
NZ (1) NZ580482A (OSRAM)
PA (1) PA8776801A1 (OSRAM)
PL (1) PL2146714T3 (OSRAM)
PT (1) PT2146714E (OSRAM)
RS (1) RS51869B (OSRAM)
SI (1) SI2146714T1 (OSRAM)
TW (1) TWI439269B (OSRAM)
UY (1) UY31035A1 (OSRAM)
WO (1) WO2008145841A1 (OSRAM)
ZA (1) ZA200907251B (OSRAM)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016500094A (ja) * 2012-11-28 2016-01-07 サノフイ 4−(シクロプロピルメトキシ)−n−(3,5−ジクロロ−1−オキシドピリジン−4−イル)−5−メトキシピリジン−2−カルボキサミドの結晶形態の製造方法およびその結晶形態
US9624100B2 (en) 2014-06-12 2017-04-18 Apple Inc. Micro pick up array pivot mount with integrated strain sensing elements
WO2025079694A1 (ja) * 2023-10-12 2025-04-17 株式会社 メドレックス 経皮吸収組成物
US20250120957A1 (en) * 2023-10-12 2025-04-17 Alto Neuroscience, Inc. Treatment of neuropsychiatric disorders with tilivapram

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4193926A (en) * 1974-03-20 1980-03-18 Schering Aktiengesellschaft 4-(Polyalkoxy phenyl)-2-pyrrolidones
JP3775685B2 (ja) * 1993-07-28 2006-05-17 ローン−プーラン・ロレ・リミテツド Pde▲iv▼およびtnf抑制剤としての化合物
US6177077B1 (en) * 1999-02-24 2001-01-23 Edward L. Tobinick TNT inhibitors for the treatment of neurological disorders
PT1244649E (pt) * 1999-12-23 2005-06-30 Icos Corp Inibidores de fosfodiesterase especificos de mfa ciclica
HUP0600103A2 (en) * 2001-03-02 2006-06-28 Bristol Myers Squibb Co Co-administration of melanocortin receptor agonist and phosphodiesterase inhibitor for treatment of cyclic-amp associated disorders
JP2005538972A (ja) * 2002-07-02 2005-12-22 メルク フロスト カナダ アンド カンパニー ジアリール置換エタンピリドンpde4阻害剤
ES2362484T3 (es) * 2003-03-12 2011-07-06 Celgene Corporation Compuestos de ácido n-alquil-hidroxámico-isoindolilo y sus usos farmacéuticos.
AU2006257863A1 (en) * 2005-06-10 2006-12-21 F. Hoffmann-La Roche Ag Trisubstituted amines as phosphodiesterase 4 inhibitors
US20070021451A1 (en) * 2005-07-20 2007-01-25 Hamamatsu University School Of Medicine Method for preventing or treating neurologic damage after spinal cord injury

Also Published As

Publication number Publication date
EA019194B1 (ru) 2014-01-30
KR20150004885A (ko) 2015-01-13
NZ580482A (en) 2011-10-28
DK2146714T3 (da) 2011-10-10
AU2008257322A1 (en) 2008-12-04
EA200970970A1 (ru) 2010-02-26
JP5386478B2 (ja) 2014-01-15
FR2915100B1 (fr) 2009-06-05
KR101503942B1 (ko) 2015-03-18
CA2684174C (fr) 2014-02-25
EP2146714A1 (fr) 2010-01-27
KR20090130059A (ko) 2009-12-17
WO2008145841A1 (fr) 2008-12-04
AU2008257322B2 (en) 2013-06-13
MA31367B1 (fr) 2010-05-03
RS51869B (sr) 2012-02-29
MY148092A (en) 2013-02-28
JP2010524906A (ja) 2010-07-22
PT2146714E (pt) 2011-09-02
AR066108A1 (es) 2009-07-22
PA8776801A1 (es) 2008-11-19
CL2008001136A1 (es) 2009-01-16
IL201448A0 (en) 2010-05-31
TWI439269B (zh) 2014-06-01
HRP20110666T1 (hr) 2011-10-31
FR2915100A1 (fr) 2008-10-24
CA2684174A1 (fr) 2008-12-04
JO2678B1 (en) 2013-03-03
ATE513548T1 (de) 2011-07-15
SI2146714T1 (sl) 2011-10-28
ZA200907251B (en) 2011-04-28
UY31035A1 (es) 2008-11-28
ME00935B (me) 2012-06-20
US20100130554A1 (en) 2010-05-27
TW200911247A (en) 2009-03-16
CN101663035A (zh) 2010-03-03
MX2009011284A (es) 2009-11-02
CY1111840T1 (el) 2015-10-07
HK1141725A1 (en) 2010-11-19
EP2146714B1 (fr) 2011-06-22
PL2146714T3 (pl) 2011-10-31
ES2367408T3 (es) 2011-11-03
IL201448A (en) 2014-08-31
CN101663035B (zh) 2012-06-20

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]
B08H Application fees: decision cancelled [chapter 8.8 patent gazette]

Free format text: ANULADA A PUBLICACAO CODIGO 8.11 NA RPI NO 2475 DE 12/06/2018 POR TER SIDO INDEVIDA. UMA VEZ QUE O PEDIDO JA TERIA RECEBIDO A MANUTENCAO DO ARQUIVAMENTO NA RPI 2474 DE 05/06/2018.