BRPI0807798A2 - " aperfeiçoamento do crescimento celular ". - Google Patents

" aperfeiçoamento do crescimento celular ".

Info

Publication number
BRPI0807798A2
BRPI0807798A2 BRPI0807798-3A2A BRPI0807798A BRPI0807798A2 BR PI0807798 A2 BRPI0807798 A2 BR PI0807798A2 BR PI0807798 A BRPI0807798 A BR PI0807798A BR PI0807798 A2 BRPI0807798 A2 BR PI0807798A2
Authority
BR
Brazil
Prior art keywords
improvement
cell growth
growth
cell
Prior art date
Application number
BRPI0807798-3A2A
Other languages
English (en)
Inventor
Hitto Kaufmann
Lore Florin
Eric Becker
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of BRPI0807798A2 publication Critical patent/BRPI0807798A2/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0012Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/66General methods for inserting a gene into a vector to form a recombinant vector using cleavage and ligation; Use of non-functional linkers or adaptors, e.g. linkers containing the sequence for a restriction endonuclease
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10Cells modified by introduction of foreign genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0012Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0026Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on CH-NH groups of donors (1.5)
    • C12N9/0028Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on CH-NH groups of donors (1.5) with NAD or NADP as acceptor (1.5.1)
    • C12N9/003Dihydrofolate reductase [DHFR] (1.5.1.3)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70Enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/998Proteins not provided for elsewhere
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00Genetically modified cells
    • C12N2510/02Cells for production
BRPI0807798-3A2A 2007-01-24 2008-01-22 " aperfeiçoamento do crescimento celular ". BRPI0807798A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07101070A EP1953222A1 (en) 2007-01-24 2007-01-24 Improvement of cell growth
PCT/EP2008/050699 WO2008090148A2 (en) 2007-01-24 2008-01-22 Improvement of cell growth

Publications (1)

Publication Number Publication Date
BRPI0807798A2 true BRPI0807798A2 (pt) 2014-06-03

Family

ID=38006916

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0807798-3A2A BRPI0807798A2 (pt) 2007-01-24 2008-01-22 " aperfeiçoamento do crescimento celular ".

Country Status (14)

Country Link
US (1) US8535940B2 (pt)
EP (2) EP1953222A1 (pt)
JP (1) JP2010516264A (pt)
KR (1) KR20090112725A (pt)
CN (1) CN101589140B (pt)
AU (1) AU2008208862B2 (pt)
BR (1) BRPI0807798A2 (pt)
CA (1) CA2675344A1 (pt)
EA (1) EA018099B1 (pt)
HK (1) HK1137482A1 (pt)
IL (1) IL199639A (pt)
MX (1) MX2009007790A (pt)
NZ (1) NZ579204A (pt)
WO (1) WO2008090148A2 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1953222A1 (en) 2007-01-24 2008-08-06 Boehringer Ingelheim Pharma GmbH & Co. KG Improvement of cell growth
WO2010010108A1 (en) * 2008-07-23 2010-01-28 Boehringer Ingelheim Pharma Gmbh & Co. Kg Improved production host cell lines
KR101706399B1 (ko) 2009-02-27 2017-02-13 노파르티스 아게 이종성 단백질을 발현하는 진핵 세포의 선택 방법
SG11201504564TA (en) 2012-12-10 2015-08-28 Seikagaku Kogyo Co Ltd Novel recombinant factor c and method for producing the same, and method for measuring endotoxin
SG11201703741TA (en) * 2014-11-12 2017-06-29 Prometic Pharma Smt Ltd Substituted aromatic compounds and pharmaceutical compositions for tissue self-repair and regeneration
CN107119018B (zh) * 2017-03-30 2020-08-18 陕西师范大学 一种抗凋亡细胞系及其建立方法和应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2238070T3 (es) 1989-04-21 2005-08-16 Amgen Inc. Receptor del tnf, proteina ligante del tnf y adn codante para estos.
US6221675B1 (en) 1989-04-21 2001-04-24 Amgen, Inc. TNF receptors, TNF binding proteins and DNAs coding for them
US5776746A (en) 1996-05-01 1998-07-07 Genitope Corporation Gene amplification methods
US20030219871A1 (en) 2002-03-28 2003-11-27 Boehringer Ingelheim Pharma Gmbh & Co. Kg Host cells having improved cell survival properties and methods to generate such cells
EP1348758A1 (en) * 2002-03-28 2003-10-01 Boehringer Ingelheim Pharma GmbH & Co.KG Host cells having improved cell survival properties and methods to generate such cells
EP1953222A1 (en) 2007-01-24 2008-08-06 Boehringer Ingelheim Pharma GmbH & Co. KG Improvement of cell growth

Also Published As

Publication number Publication date
HK1137482A1 (en) 2010-07-30
CA2675344A1 (en) 2008-07-31
EA200900984A1 (ru) 2010-02-26
WO2008090148A3 (en) 2008-09-18
EP1953222A1 (en) 2008-08-06
AU2008208862A1 (en) 2008-07-31
IL199639A (en) 2013-08-29
EP2126061A2 (en) 2009-12-02
NZ579204A (en) 2012-04-27
EA018099B1 (ru) 2013-05-30
IL199639A0 (en) 2010-04-15
JP2010516264A (ja) 2010-05-20
KR20090112725A (ko) 2009-10-28
MX2009007790A (es) 2009-07-31
US20100086967A1 (en) 2010-04-08
US8535940B2 (en) 2013-09-17
CN101589140B (zh) 2013-04-17
WO2008090148A2 (en) 2008-07-31
CN101589140A (zh) 2009-11-25
AU2008208862B2 (en) 2014-05-08

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2344 DE 08-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.