BRPI0721039A2 - " derivados de quinuclidinol como antagonistas de receptores muscarínicos ". - Google Patents

" derivados de quinuclidinol como antagonistas de receptores muscarínicos ". Download PDF

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Publication number
BRPI0721039A2
BRPI0721039A2 BRPI0721039-6A BRPI0721039A BRPI0721039A2 BR PI0721039 A2 BRPI0721039 A2 BR PI0721039A2 BR PI0721039 A BRPI0721039 A BR PI0721039A BR PI0721039 A2 BRPI0721039 A2 BR PI0721039A2
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BR
Brazil
Prior art keywords
octane
azoniabicyclo
alkyl
phenyl
piperidin
Prior art date
Application number
BRPI0721039-6A
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English (en)
Portuguese (pt)
Inventor
Rhonan Ford
Antonio Mete
Ian Millichip
Barry Teobald
Original Assignee
Astrazeneca Ab
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Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of BRPI0721039A2 publication Critical patent/BRPI0721039A2/pt

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
    • A—HUMAN NECESSITIES
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    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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BRPI0721039-6A 2006-12-19 2007-12-17 " derivados de quinuclidinol como antagonistas de receptores muscarínicos ". BRPI0721039A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US87063806P 2006-12-19 2006-12-19
US60/870,638 2006-12-19
PCT/GB2007/004817 WO2008075005A1 (en) 2006-12-19 2007-12-17 Quinuclidinol derivatives as muscarinic receptor antagonists

Publications (1)

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BRPI0721039A2 true BRPI0721039A2 (pt) 2014-07-29

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US20100113510A1 (en) 2010-05-06
PE20081837A1 (es) 2009-02-07
JP4604129B2 (ja) 2010-12-22
UY30803A1 (es) 2008-07-31
RU2009120229A (ru) 2011-01-27
CA2672446A1 (en) 2008-06-26
NO20092689L (no) 2009-09-14
WO2008075005A1 (en) 2008-06-26
AR064414A1 (es) 2009-04-01
EP2121137B1 (en) 2012-04-25
IL199015A0 (en) 2010-02-17
ATE555111T1 (de) 2012-05-15
CO6180439A2 (es) 2010-07-19
CL2007003690A1 (es) 2008-08-22
TW200831507A (en) 2008-08-01
CN101610813A (zh) 2009-12-23
KR20090094460A (ko) 2009-09-07
ES2385681T3 (es) 2012-07-30
ECSP099394A (es) 2009-07-31
MX2009006018A (es) 2009-06-16
AU2007336054A1 (en) 2008-06-26
JP2010513434A (ja) 2010-04-30
EP2121137A1 (en) 2009-11-25

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