BRPI0720261A2 - Detector de cromatografia de líquido e controlador de corrente para o mesmo - Google Patents
Detector de cromatografia de líquido e controlador de corrente para o mesmo Download PDFInfo
- Publication number
- BRPI0720261A2 BRPI0720261A2 BRPI0720261-0A BRPI0720261A BRPI0720261A2 BR PI0720261 A2 BRPI0720261 A2 BR PI0720261A2 BR PI0720261 A BRPI0720261 A BR PI0720261A BR PI0720261 A2 BRPI0720261 A2 BR PI0720261A2
- Authority
- BR
- Brazil
- Prior art keywords
- liquid chromatography
- current
- current controller
- chromatography detector
- detector according
- Prior art date
Links
- 238000004811 liquid chromatography Methods 0.000 title claims description 40
- 239000006199 nebulizer Substances 0.000 claims description 47
- 238000001514 detection method Methods 0.000 claims description 19
- 239000007788 liquid Substances 0.000 claims description 9
- 239000012159 carrier gas Substances 0.000 claims description 7
- 238000004458 analytical method Methods 0.000 claims description 6
- 239000000463 material Substances 0.000 claims description 6
- 229910052751 metal Inorganic materials 0.000 claims description 4
- 239000002184 metal Substances 0.000 claims description 4
- 238000009795 derivation Methods 0.000 claims 1
- 238000002663 nebulization Methods 0.000 claims 1
- 238000000105 evaporative light scattering detection Methods 0.000 description 19
- JYGXADMDTFJGBT-VWUMJDOOSA-N hydrocortisone Chemical compound O=C1CC[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 JYGXADMDTFJGBT-VWUMJDOOSA-N 0.000 description 12
- 230000035945 sensitivity Effects 0.000 description 7
- 229960000890 hydrocortisone Drugs 0.000 description 6
- 239000000443 aerosol Substances 0.000 description 4
- 239000002245 particle Substances 0.000 description 4
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 description 3
- 238000010276 construction Methods 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 238000001704 evaporation Methods 0.000 description 3
- 230000008020 evaporation Effects 0.000 description 3
- 239000002904 solvent Substances 0.000 description 3
- 229910001220 stainless steel Inorganic materials 0.000 description 3
- 239000010935 stainless steel Substances 0.000 description 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- 229920006362 Teflon® Polymers 0.000 description 2
- 230000005494 condensation Effects 0.000 description 2
- 238000009833 condensation Methods 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 239000007789 gas Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 230000010355 oscillation Effects 0.000 description 2
- 208000032364 Undersensing Diseases 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 238000000149 argon plasma sintering Methods 0.000 description 1
- 230000005465 channeling Effects 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 150000001875 compounds Chemical group 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 230000005684 electric field Effects 0.000 description 1
- 238000004128 high performance liquid chromatography Methods 0.000 description 1
- 239000011261 inert gas Substances 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 239000003595 mist Substances 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 238000004704 ultra performance liquid chromatography Methods 0.000 description 1
- 238000011144 upstream manufacturing Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/62—Detectors specially adapted therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/84—Preparation of the fraction to be distributed
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N11/00—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties
- G01N11/02—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by measuring flow of the material
- G01N11/04—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by measuring flow of the material through a restricted passage, e.g. tube, aperture
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/62—Detectors specially adapted therefor
- G01N30/74—Optical detectors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/84—Preparation of the fraction to be distributed
- G01N2030/8447—Nebulising, aerosol formation or ionisation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/84—Preparation of the fraction to be distributed
- G01N2030/8447—Nebulising, aerosol formation or ionisation
- G01N2030/847—Nebulising, aerosol formation or ionisation by pneumatic means
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/84—Preparation of the fraction to be distributed
- G01N2030/8447—Nebulising, aerosol formation or ionisation
- G01N2030/8494—Desolvation chambers
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Sampling And Sample Adjustment (AREA)
- Flow Control (AREA)
- Optical Measuring Cells (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86892606P | 2006-12-06 | 2006-12-06 | |
| US60/868,926 | 2006-12-06 | ||
| PCT/US2007/086641 WO2008070776A2 (en) | 2006-12-06 | 2007-12-06 | Liquid chromatography detector and flow controller therefor |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0720261A2 true BRPI0720261A2 (pt) | 2014-02-25 |
Family
ID=39493069
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0720261-0A BRPI0720261A2 (pt) | 2006-12-06 | 2007-12-06 | Detector de cromatografia de líquido e controlador de corrente para o mesmo |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US8397553B2 (OSRAM) |
| EP (1) | EP2089687A4 (OSRAM) |
| JP (1) | JP2010512514A (OSRAM) |
| KR (1) | KR20090120457A (OSRAM) |
| CN (1) | CN101646933A (OSRAM) |
| AU (1) | AU2007329303A1 (OSRAM) |
| BR (1) | BRPI0720261A2 (OSRAM) |
| CA (1) | CA2671380A1 (OSRAM) |
| MX (1) | MX2009006096A (OSRAM) |
| NO (1) | NO20092568L (OSRAM) |
| RU (1) | RU2009125587A (OSRAM) |
| WO (1) | WO2008070776A2 (OSRAM) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103630642B (zh) | 2007-12-05 | 2016-08-17 | 全技术联合公司 | 用于分析样本和收集样本流份的方法和装置 |
| WO2009152321A1 (en) * | 2008-06-11 | 2009-12-17 | The Curators Of The University Of Missouri | Liquid chromatography detector and flow controller therefor |
| SG10201400369QA (en) * | 2008-12-04 | 2014-05-29 | Alltech Associates Inc | Methods and apparatus for moving aliquot samples of fluid |
| US9086422B2 (en) | 2008-12-10 | 2015-07-21 | Alltech Associates, Inc. | Chromatography systems and system components |
| US8305582B2 (en) | 2009-09-01 | 2012-11-06 | Alltech Associates, Inc. | Methods and apparatus for analyzing samples and collecting sample fractions |
| WO2011140345A1 (en) * | 2010-05-07 | 2011-11-10 | Alltech Associates, Inc. | Methods and apparatus for analyzing samples and collecting sample fractions |
| FR3000111B1 (fr) * | 2012-12-21 | 2015-01-02 | Seb Sa | Appareil de repassage a la vapeur comportant un generateur de vapeur sous pression et un fer a repasser |
| US11582900B2 (en) * | 2020-01-17 | 2023-02-21 | Cnh Industrial Canada, Ltd. | Distribution orifice system for a dry agricultural product applicator |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3808550A (en) | 1969-12-15 | 1974-04-30 | Bell Telephone Labor Inc | Apparatuses for trapping and accelerating neutral particles |
| US3894562A (en) * | 1973-12-20 | 1975-07-15 | Jr Charles D Moseley | Fluid flow controller |
| US4426213A (en) * | 1980-11-17 | 1984-01-17 | Engineering Resources, Inc. | Condensate removal device for steam lines and the like |
| JPS62118255A (ja) | 1985-11-19 | 1987-05-29 | Toshimitsu Musha | 磁界を用いた免疫反応の検出法 |
| US4941618A (en) * | 1986-07-07 | 1990-07-17 | Leeman Labs Inc. | Nebulizer employing a fine mesh screen |
| DE3841979A1 (de) | 1988-12-14 | 1990-06-21 | Teldix Gmbh | Rueckstreuungsfreie lichtfalle |
| US4990740A (en) * | 1989-03-06 | 1991-02-05 | The Dow Chemical Company | Intra-microspray ICP torch |
| US5061065A (en) | 1989-10-20 | 1991-10-29 | Pacific Scientific Company | Particle contamination detection in fluids through the external section of a laser |
| US4958529A (en) * | 1989-11-22 | 1990-09-25 | Vestec Corporation | Interface for coupling liquid chromatography to solid or gas phase detectors |
| JP2633974B2 (ja) * | 1990-04-18 | 1997-07-23 | 株式会社日立製作所 | 試料のイオン化および質量分析のための装置 |
| JP3087548B2 (ja) | 1993-12-09 | 2000-09-11 | 株式会社日立製作所 | 液体クロマトグラフ結合型質量分析装置 |
| US5529244A (en) | 1994-10-04 | 1996-06-25 | S. C. Johnson & Son, Inc. | Aspirator liquid blending device using multiple restrictors |
| US5837826A (en) * | 1995-02-27 | 1998-11-17 | Regents Of The University Of Minnesota | Protein adsorption by very dense porous zirconium oxide particles in expanded beds |
| US5872622A (en) | 1996-08-12 | 1999-02-16 | Met One, Inc. | Condensation nucleus counter having vapor stabilization and working fluid recovery |
| US6362880B1 (en) | 1997-09-17 | 2002-03-26 | Alltech Associates, Inc. | Low temperature adaptor for evaporative light detection |
| WO1999032174A1 (de) | 1997-12-19 | 1999-07-01 | Arithmed Gmbh | Tragbarer medikamentspender zur zeitversetzten verabreichung von injektions- oder infusionspräparaten |
| US6024129A (en) * | 1998-07-16 | 2000-02-15 | Schima; Frank E. | Production efficient venturi insert |
| EP1166085A2 (en) | 1999-02-25 | 2002-01-02 | Clemson University Research Foundation | Sampling and analysis of airborne particulate matter by glow discharge atomic emission and mass spectrometries |
| CA2382647A1 (en) | 1999-05-17 | 2000-11-23 | Kevin S. Marchitto | Electromagnetic energy driven separation methods |
| US6229605B1 (en) | 2000-03-10 | 2001-05-08 | Alltech Associates, Inc. | Evaporative light scattering device |
| US20020186263A1 (en) | 2001-06-07 | 2002-12-12 | Nanostream, Inc. | Microfluidic fraction collectors |
| JP2003222612A (ja) * | 2002-01-30 | 2003-08-08 | Hitachi High-Technologies Corp | 大気圧イオン化質量分析装置および分析方法 |
| US6903818B2 (en) | 2002-10-28 | 2005-06-07 | Particle Measuring Systems, Inc. | Low noise intracavity laser particle counter |
| GB0304253D0 (en) | 2003-02-25 | 2003-03-26 | Polymer Lab Ltd | Apparatus |
| US7114525B2 (en) | 2003-08-29 | 2006-10-03 | Dana Corporation | Method and apparatus for reduction of fluid-borne noise in hydraulic systems |
| US7268881B2 (en) | 2004-02-17 | 2007-09-11 | The Curators Of The University Of Missouri | Light scattering detector |
| WO2005106350A2 (en) * | 2004-04-23 | 2005-11-10 | Philip Morris Usa Inc. | Aerosol generators and methods for producing aerosols |
| JP4453537B2 (ja) * | 2004-12-14 | 2010-04-21 | 株式会社島津製作所 | 大気圧イオン化質量分析装置 |
| WO2006083511A2 (en) * | 2005-01-18 | 2006-08-10 | Waters Investments Limited | Evaporative light scattering detector |
| US7760355B2 (en) | 2005-07-27 | 2010-07-20 | The Curators Of The University Of Missouri | Focused droplet nebulizer for evaporative light scattering detector |
| EP3034119B1 (en) * | 2006-03-30 | 2018-03-21 | Vyaire Medical Consumables LLC | Nebulizer with pressure-based fluidic-control |
-
2007
- 2007-12-06 RU RU2009125587/05A patent/RU2009125587A/ru not_active Application Discontinuation
- 2007-12-06 BR BRPI0720261-0A patent/BRPI0720261A2/pt not_active Application Discontinuation
- 2007-12-06 KR KR1020097013942A patent/KR20090120457A/ko not_active Withdrawn
- 2007-12-06 MX MX2009006096A patent/MX2009006096A/es unknown
- 2007-12-06 AU AU2007329303A patent/AU2007329303A1/en not_active Abandoned
- 2007-12-06 JP JP2009540475A patent/JP2010512514A/ja active Pending
- 2007-12-06 EP EP07865307A patent/EP2089687A4/en not_active Withdrawn
- 2007-12-06 WO PCT/US2007/086641 patent/WO2008070776A2/en not_active Ceased
- 2007-12-06 US US12/517,946 patent/US8397553B2/en not_active Expired - Fee Related
- 2007-12-06 CA CA002671380A patent/CA2671380A1/en not_active Abandoned
- 2007-12-06 CN CN200780049321A patent/CN101646933A/zh active Pending
-
2009
- 2009-07-06 NO NO20092568A patent/NO20092568L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2671380A1 (en) | 2008-06-12 |
| RU2009125587A (ru) | 2011-01-20 |
| WO2008070776A2 (en) | 2008-06-12 |
| CN101646933A (zh) | 2010-02-10 |
| NO20092568L (no) | 2009-09-04 |
| AU2007329303A1 (en) | 2008-06-12 |
| US20110005305A1 (en) | 2011-01-13 |
| JP2010512514A (ja) | 2010-04-22 |
| WO2008070776A3 (en) | 2008-07-31 |
| US8397553B2 (en) | 2013-03-19 |
| MX2009006096A (es) | 2009-10-26 |
| KR20090120457A (ko) | 2009-11-24 |
| EP2089687A4 (en) | 2010-04-14 |
| EP2089687A2 (en) | 2009-08-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
| B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |