BRPI0718639A2 - Usos de uma bactéria e de um sobrenadante de cultura de clostridium perfringens tipo c - Google Patents
Usos de uma bactéria e de um sobrenadante de cultura de clostridium perfringens tipo c Download PDFInfo
- Publication number
- BRPI0718639A2 BRPI0718639A2 BRPI0718639-8A BRPI0718639A BRPI0718639A2 BR PI0718639 A2 BRPI0718639 A2 BR PI0718639A2 BR PI0718639 A BRPI0718639 A BR PI0718639A BR PI0718639 A2 BRPI0718639 A2 BR PI0718639A2
- Authority
- BR
- Brazil
- Prior art keywords
- clostridium perfringens
- perfringens type
- vaccine
- infection
- manufacture
- Prior art date
Links
- 244000309714 Clostridium perfringens type C Species 0.000 title claims abstract description 47
- 241000894006 Bacteria Species 0.000 title description 2
- 229960005486 vaccine Drugs 0.000 claims abstract description 59
- 241000193468 Clostridium perfringens Species 0.000 claims abstract description 38
- 208000015181 infectious disease Diseases 0.000 claims abstract description 27
- 239000000427 antigen Substances 0.000 claims description 22
- 108091007433 antigens Proteins 0.000 claims description 22
- 102000036639 antigens Human genes 0.000 claims description 22
- 238000004519 manufacturing process Methods 0.000 claims description 21
- 241000282887 Suidae Species 0.000 claims description 19
- 241000700605 Viruses Species 0.000 claims description 13
- 239000012228 culture supernatant Substances 0.000 claims description 13
- 239000003053 toxin Substances 0.000 claims description 11
- 231100000765 toxin Toxicity 0.000 claims description 11
- 244000052769 pathogen Species 0.000 claims description 5
- 230000001717 pathogenic effect Effects 0.000 claims description 5
- 241000186810 Erysipelothrix rhusiopathiae Species 0.000 claims description 3
- 208000005342 Porcine Reproductive and Respiratory Syndrome Diseases 0.000 claims description 3
- 241000702670 Rotavirus Species 0.000 claims description 3
- 241000293869 Salmonella enterica subsp. enterica serovar Typhimurium Species 0.000 claims description 3
- 241000701093 Suid alphaherpesvirus 1 Species 0.000 claims description 3
- 241000711484 Transmissible gastroenteritis virus Species 0.000 claims description 3
- 241000712461 unidentified influenza virus Species 0.000 claims description 3
- 241000588722 Escherichia Species 0.000 claims description 2
- 241000606807 Glaesserella parasuis Species 0.000 claims description 2
- 241000194021 Streptococcus suis Species 0.000 claims description 2
- 230000002068 genetic effect Effects 0.000 claims description 2
- 241000588779 Bordetella bronchiseptica Species 0.000 claims 1
- 241000606856 Pasteurella multocida Species 0.000 claims 1
- 241001138501 Salmonella enterica Species 0.000 claims 1
- 229940051027 pasteurella multocida Drugs 0.000 claims 1
- 241000282898 Sus scrofa Species 0.000 abstract description 7
- 108700012359 toxins Proteins 0.000 description 10
- 241001112695 Clostridiales Species 0.000 description 7
- 238000002255 vaccination Methods 0.000 description 6
- 241001112696 Clostridia Species 0.000 description 3
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 3
- 241001465754 Metazoa Species 0.000 description 3
- 230000001200 fecal consistency Effects 0.000 description 3
- 230000002550 fecal effect Effects 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 241000606748 Actinobacillus pleuropneumoniae Species 0.000 description 2
- 241000588807 Bordetella Species 0.000 description 2
- 241000282472 Canis lupus familiaris Species 0.000 description 2
- 206010061043 Clostridial infection Diseases 0.000 description 2
- 206010012735 Diarrhoea Diseases 0.000 description 2
- 241000283086 Equidae Species 0.000 description 2
- 241000588724 Escherichia coli Species 0.000 description 2
- 241000287828 Gallus gallus Species 0.000 description 2
- 241000282412 Homo Species 0.000 description 2
- 241000607142 Salmonella Species 0.000 description 2
- 230000002411 adverse Effects 0.000 description 2
- 235000021407 appetite control Nutrition 0.000 description 2
- 235000013330 chicken meat Nutrition 0.000 description 2
- 210000003022 colostrum Anatomy 0.000 description 2
- 235000021277 colostrum Nutrition 0.000 description 2
- 239000012141 concentrate Substances 0.000 description 2
- 206010061428 decreased appetite Diseases 0.000 description 2
- 230000037406 food intake Effects 0.000 description 2
- 235000012631 food intake Nutrition 0.000 description 2
- 210000001035 gastrointestinal tract Anatomy 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 230000003862 health status Effects 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 208000028774 intestinal disease Diseases 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 210000003097 mucus Anatomy 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 239000006228 supernatant Substances 0.000 description 2
- 230000003442 weekly effect Effects 0.000 description 2
- 101710092462 Alpha-hemolysin Proteins 0.000 description 1
- 101710197219 Alpha-toxin Proteins 0.000 description 1
- 208000031295 Animal disease Diseases 0.000 description 1
- 201000004569 Blindness Diseases 0.000 description 1
- 241000283690 Bos taurus Species 0.000 description 1
- 241000283707 Capra Species 0.000 description 1
- 241000700199 Cavia porcellus Species 0.000 description 1
- 241000193163 Clostridioides difficile Species 0.000 description 1
- 241000193403 Clostridium Species 0.000 description 1
- 208000037384 Clostridium Infections Diseases 0.000 description 1
- 206010022678 Intestinal infections Diseases 0.000 description 1
- 206010024264 Lethargy Diseases 0.000 description 1
- 241000283903 Ovis aries Species 0.000 description 1
- 241001494479 Pecora Species 0.000 description 1
- 101710124951 Phospholipase C Proteins 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 239000002776 alpha toxin Substances 0.000 description 1
- 230000003698 anagen phase Effects 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 244000052616 bacterial pathogen Species 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 244000309466 calf Species 0.000 description 1
- 229940001442 combination vaccine Drugs 0.000 description 1
- 230000000994 depressogenic effect Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 208000010227 enterocolitis Diseases 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 230000012010 growth Effects 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 210000000987 immune system Anatomy 0.000 description 1
- 230000016784 immunoglobulin production Effects 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 230000000968 intestinal effect Effects 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000001338 necrotic effect Effects 0.000 description 1
- 230000008506 pathogenesis Effects 0.000 description 1
- 239000008188 pellet Substances 0.000 description 1
- 230000035935 pregnancy Effects 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000000384 rearing effect Effects 0.000 description 1
- 238000007619 statistical method Methods 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 229940031572 toxoid vaccine Drugs 0.000 description 1
- 238000000108 ultra-filtration Methods 0.000 description 1
- 241001148471 unidentified anaerobic bacterium Species 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/08—Clostridium, e.g. Clostridium tetani
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US86044706P | 2006-11-20 | 2006-11-20 | |
| EP06124404.2 | 2006-11-20 | ||
| US60/860,447 | 2006-11-20 | ||
| EP06124404 | 2006-11-20 | ||
| PCT/EP2007/062484 WO2008061950A1 (en) | 2006-11-20 | 2007-11-19 | Use of clostridium perfringens type c bacterium for the manufacture of a vaccine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0718639A2 true BRPI0718639A2 (pt) | 2013-11-26 |
Family
ID=38535530
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0718639-8A BRPI0718639A2 (pt) | 2006-11-20 | 2007-11-19 | Usos de uma bactéria e de um sobrenadante de cultura de clostridium perfringens tipo c |
Country Status (8)
| Country | Link |
|---|---|
| CN (1) | CN101541343B (de) |
| AT (1) | ATE540692T1 (de) |
| BR (1) | BRPI0718639A2 (de) |
| DK (1) | DK2086578T3 (de) |
| ES (1) | ES2380134T3 (de) |
| RU (1) | RU2462263C2 (de) |
| TW (1) | TWI369991B (de) |
| UA (1) | UA95652C2 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102688484B (zh) * | 2012-06-13 | 2016-03-30 | 北京中海生物科技有限公司 | 一种鸡坏死性肠炎（c型）灭活疫苗的生产方法 |
| CN107789622A (zh) * | 2017-10-18 | 2018-03-13 | 山东农业大学 | 一种犊牛肠毒血症产气荚膜梭菌β2毒素类毒素疫苗的制备方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2129441C1 (ru) * | 1997-12-10 | 1999-04-27 | Пирожков Михаил Константинович | Вакцина, ассоциированная против анаэробной энтеротоксемии и эшерихиоза поросят |
-
2007
- 2007-10-26 TW TW096140460A patent/TWI369991B/zh not_active IP Right Cessation
- 2007-11-19 ES ES07822693T patent/ES2380134T3/es active Active
- 2007-11-19 UA UAA200904648A patent/UA95652C2/ru unknown
- 2007-11-19 BR BRPI0718639-8A patent/BRPI0718639A2/pt not_active Application Discontinuation
- 2007-11-19 DK DK07822693.3T patent/DK2086578T3/da active
- 2007-11-19 AT AT07822693T patent/ATE540692T1/de active
- 2007-11-19 CN CN2007800427077A patent/CN101541343B/zh not_active Expired - Fee Related
- 2007-11-19 RU RU2009123478/10A patent/RU2462263C2/ru not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| ES2380134T3 (es) | 2012-05-08 |
| CN101541343B (zh) | 2012-05-16 |
| DK2086578T3 (da) | 2012-05-14 |
| ATE540692T1 (de) | 2012-01-15 |
| TW200831121A (en) | 2008-08-01 |
| CN101541343A (zh) | 2009-09-23 |
| RU2009123478A (ru) | 2010-12-27 |
| UA95652C2 (ru) | 2011-08-25 |
| TWI369991B (en) | 2012-08-11 |
| RU2462263C2 (ru) | 2012-09-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8O, 13, 24, 25 DA LPI |
|
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL. |