BRPI0718491A2 - Conjugados poliméricos do box-a da hmgb1 e variantes do box-a da hmbg1 - Google Patents

Conjugados poliméricos do box-a da hmgb1 e variantes do box-a da hmbg1 Download PDF

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Publication number
BRPI0718491A2
BRPI0718491A2 BRPI0718491-3A BRPI0718491A BRPI0718491A2 BR PI0718491 A2 BRPI0718491 A2 BR PI0718491A2 BR PI0718491 A BRPI0718491 A BR PI0718491A BR PI0718491 A2 BRPI0718491 A2 BR PI0718491A2
Authority
BR
Brazil
Prior art keywords
lys
glu
wing
phe
arg
Prior art date
Application number
BRPI0718491-3A
Other languages
English (en)
Portuguese (pt)
Inventor
Silvio Traversa
Chiara Lorenzetto
Valentina Mainero
Sebastiano Morena
Silvano Fumero
Luca Beccaria
Original Assignee
Creabilis Therapeutics Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Creabilis Therapeutics Spa filed Critical Creabilis Therapeutics Spa
Priority claimed from PCT/EP2007/008029 external-priority patent/WO2008031612A1/en
Publication of BRPI0718491A2 publication Critical patent/BRPI0718491A2/pt

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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
BRPI0718491-3A 2006-09-15 2007-09-14 Conjugados poliméricos do box-a da hmgb1 e variantes do box-a da hmbg1 BRPI0718491A2 (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP06019362.0 2006-09-15
EP06019362 2006-09-15
US90477607P 2007-03-05 2007-03-05
US60/904.776 2007-03-05
PCT/EP2007/008029 WO2008031612A1 (en) 2006-09-15 2007-09-14 Polymer conjugates of box-a of hmgb1 and box-a variants of hmgb1

Publications (1)

Publication Number Publication Date
BRPI0718491A2 true BRPI0718491A2 (pt) 2013-12-03

Family

ID=41095680

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0718491-3A BRPI0718491A2 (pt) 2006-09-15 2007-09-14 Conjugados poliméricos do box-a da hmgb1 e variantes do box-a da hmbg1

Country Status (8)

Country Link
CN (1) CN101528266B (sl)
AT (1) ATE505205T1 (sl)
BR (1) BRPI0718491A2 (sl)
DE (1) DE602007013919D1 (sl)
DK (1) DK2068935T3 (sl)
PT (1) PT2068935E (sl)
RU (1) RU2458070C2 (sl)
SI (1) SI2068935T1 (sl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT3358011T (pt) * 2011-04-26 2020-04-23 Univ Osaka Péptido para induzir a regeneração de um tecido e a sua utilização
CN102443064A (zh) * 2011-11-03 2012-05-09 刘誉 一种基于凝血酶活性的双靶向作用的嵌合多肽及其应用
CN103893754A (zh) * 2012-12-26 2014-07-02 深圳先进技术研究院 Dna-壳聚糖复合纳米颗粒、其制备及应用
US9775885B2 (en) * 2016-01-29 2017-10-03 Kaohsiung Medical Univeristy TMD1 protein for treating bone loss diseases
CN113423466A (zh) * 2018-10-25 2021-09-21 国立大学法人大阪大学 软骨病症的治疗剂
CN114957440A (zh) * 2022-05-26 2022-08-30 江苏大学 一种重组HMGB1 A Box蛋白及其获取方法与应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030060410A1 (en) * 2001-05-15 2003-03-27 North Shore Long Island Jewish Research Institute Use of HMG fragments as anti-inflammatory agents
EP1814576A2 (en) * 2004-07-20 2007-08-08 Critical Therapeutics, Inc. Combination therapies of hmgb and complement inhibitors against inflammation
MX2007002557A (es) * 2004-09-03 2007-10-10 Creabilis Therapeutics Spa Uso de polipeptidos obtenidos a traves de mutaciones sistematicas de aminoacidos unicos de bloque-a humano y no humano de hmgb1 para prevenir y/o antagonizar las patologias inducidas por hmgb1.

Also Published As

Publication number Publication date
CN101528266B (zh) 2012-11-07
DE602007013919D1 (de) 2011-05-26
RU2009114149A (ru) 2010-10-20
RU2458070C2 (ru) 2012-08-10
PT2068935E (pt) 2011-07-08
CN101528266A (zh) 2009-09-09
SI2068935T1 (sl) 2011-07-29
ATE505205T1 (de) 2011-04-15
DK2068935T3 (da) 2011-08-01

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Legal Events

Date Code Title Description
B15K Others concerning applications: alteration of classification

Ipc: A61K 47/00 (2006.01), A61M 25/00 (2006.01), C07K 1

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements