BRPI0715817A2 - Compostos de 1h-quinolin-4-ona, com afinidade para o receptor gaba, processos, usos, e composições - Google Patents
Compostos de 1h-quinolin-4-ona, com afinidade para o receptor gaba, processos, usos, e composiçõesInfo
- Publication number
- BRPI0715817A2 BRPI0715817A2 BRPI0715817-3A2A BRPI0715817A BRPI0715817A2 BR PI0715817 A2 BRPI0715817 A2 BR PI0715817A2 BR PI0715817 A BRPI0715817 A BR PI0715817A BR PI0715817 A2 BRPI0715817 A2 BR PI0715817A2
- Authority
- BR
- Brazil
- Prior art keywords
- gaba
- quinolin
- affinity
- receiver
- compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/04—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms
- C07D215/06—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms having only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/18—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US83666606P | 2006-08-10 | 2006-08-10 | |
| EP06118720A EP1886996A1 (en) | 2006-08-10 | 2006-08-10 | 1H-Quinolin-4-one compounds, with affinity for the GABA receptor, processes, uses and compositions |
| PCT/EP2007/058288 WO2008017710A1 (en) | 2006-08-10 | 2007-08-09 | 1h-quinolin-4-one compounds, with affinity for the gaba receptor, processes, uses and compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0715817A2 true BRPI0715817A2 (pt) | 2014-12-23 |
Family
ID=37651083
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0715817-3A2A BRPI0715817A2 (pt) | 2006-08-10 | 2007-08-09 | Compostos de 1h-quinolin-4-ona, com afinidade para o receptor gaba, processos, usos, e composições |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20100168099A1 (pt) |
| EP (1) | EP1886996A1 (pt) |
| CN (1) | CN101522630A (pt) |
| AR (1) | AR062295A1 (pt) |
| AT (1) | ATE512138T1 (pt) |
| BR (1) | BRPI0715817A2 (pt) |
| CL (1) | CL2007002324A1 (pt) |
| DK (1) | DK2064185T3 (pt) |
| PT (1) | PT2064185E (pt) |
| RU (1) | RU2009108361A (pt) |
| SI (1) | SI2064185T1 (pt) |
| TW (1) | TW200833665A (pt) |
| UY (1) | UY30529A1 (pt) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI366565B (en) | 2007-06-06 | 2012-06-21 | Otsuka Pharma Co Ltd | Quinolone compound and pharmaceutical composition |
| TWI472525B (zh) * | 2008-12-05 | 2015-02-11 | Otsuka Pharma Co Ltd | 喹啉酮化合物及藥學組成物 |
| JP5769504B2 (ja) * | 2010-06-04 | 2015-08-26 | 大塚製薬株式会社 | 医薬 |
| KR20140138694A (ko) | 2012-02-03 | 2014-12-04 | 테바 파마슈티컬 인더스트리즈 리미티드 | 최선의 항-TNFα 요법에 실패한 크론병 환자를 치료하기 위한 라퀴니모드의 용도 |
| TW201400117A (zh) | 2012-06-05 | 2014-01-01 | Teva Pharma | 使用拉喹莫德治療眼發炎疾病 |
| TW201410244A (zh) * | 2012-08-13 | 2014-03-16 | Teva Pharma | 用於治療ｇａｂａ媒介之疾病之拉喹莫德（ｌａｑｕｉｎｉｍｏｄ） |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2728900B1 (fr) * | 1994-12-29 | 1997-01-31 | Synthelabo | Derives de 3-phenylisoquinolein-1(2h)-one, leur preparation et leur application en therapeutique |
| GB9621757D0 (en) * | 1996-10-18 | 1996-12-11 | Ciba Geigy Ag | Phenyl-substituted bicyclic heterocyclyl derivatives and their use |
| FR2813791B1 (fr) * | 2000-09-14 | 2004-03-12 | Lafon Labor | Utilisation de 2- et 4-quinolones pour inhiber la neo-proliferation intimale |
| ES2319176T3 (es) * | 2002-05-14 | 2009-05-05 | The Regents Of The University Of California | Acidos quinolona-carboxilicos sustituidos, sus derivados, sitio de accion y uso de los mismos. |
-
2006
- 2006-08-10 EP EP06118720A patent/EP1886996A1/en not_active Withdrawn
-
2007
- 2007-08-06 TW TW096128818A patent/TW200833665A/zh unknown
- 2007-08-07 UY UY30529A patent/UY30529A1/es unknown
- 2007-08-09 PT PT07788348T patent/PT2064185E/pt unknown
- 2007-08-09 CL CL2007002324A patent/CL2007002324A1/es unknown
- 2007-08-09 CN CNA2007800365992A patent/CN101522630A/zh active Pending
- 2007-08-09 RU RU2009108361/04A patent/RU2009108361A/ru not_active Application Discontinuation
- 2007-08-09 DK DK07788348.6T patent/DK2064185T3/da active
- 2007-08-09 SI SI200730707T patent/SI2064185T1/sl unknown
- 2007-08-09 AT AT07788348T patent/ATE512138T1/de active
- 2007-08-09 US US12/377,103 patent/US20100168099A1/en not_active Abandoned
- 2007-08-09 AR ARP070103514A patent/AR062295A1/es unknown
- 2007-08-09 BR BRPI0715817-3A2A patent/BRPI0715817A2/pt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| SI2064185T1 (sl) | 2011-10-28 |
| UY30529A1 (es) | 2008-02-29 |
| AR062295A1 (es) | 2008-10-29 |
| CN101522630A (zh) | 2009-09-02 |
| TW200833665A (en) | 2008-08-16 |
| PT2064185E (pt) | 2011-09-12 |
| EP1886996A1 (en) | 2008-02-13 |
| ATE512138T1 (de) | 2011-06-15 |
| CL2007002324A1 (es) | 2008-01-18 |
| RU2009108361A (ru) | 2010-09-20 |
| DK2064185T3 (da) | 2011-09-19 |
| US20100168099A1 (en) | 2010-07-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL230759A0 (en) | Converted acyl anilide, the pharmaceutical composition containing it and its uses | |
| BRPI0716094A2 (pt) | composiÇço de resina. | |
| BRPI0814010A2 (pt) | Composição de aço | |
| BRPI0716325A2 (pt) | Composição antimicrobianas | |
| EP2123158A4 (en) | HERBICIDE COMPOSITION | |
| BRPI0921063A2 (pt) | Composto, e, composição agonística para o receptor de melanocortina. | |
| BRPI0915731A2 (pt) | composição de graxa. | |
| FR2899479B1 (fr) | Composition cicatrisante | |
| ATE513831T1 (de) | Pyridinä3,4-büpyrazinone | |
| BRPI0915732A2 (pt) | composição de graxa. | |
| BRPI0716458A2 (pt) | Composição de vulcanizado | |
| BRPI0815246A2 (pt) | Composição de catalisador | |
| FR2921069B1 (fr) | Composition polyamide | |
| DE502007005744D1 (de) | Schallgedämpftes, gasführendes Bauteil | |
| DK2107865T3 (da) | Køretøj til udbringning af gylle | |
| BRPI0718141A2 (pt) | Composições de frangrâncias | |
| FR2905563B1 (fr) | Composition alimentaire. | |
| BRPI0814748A2 (pt) | Compostos de alditóis substituídos, composições e métodos | |
| BRPI0821249A2 (pt) | Composição de endurecimento | |
| ZA200807960B (en) | Catalyst composition | |
| BRPI0715817A2 (pt) | Compostos de 1h-quinolin-4-ona, com afinidade para o receptor gaba, processos, usos, e composições | |
| FR2908418B1 (fr) | Composition de polyamide ignifugee. | |
| FR2932490B1 (fr) | Composition polyamide. | |
| EP2042556A4 (en) | POLYAMIDE COMPOSITION | |
| FR2923713B1 (fr) | Composition reductrice epaissie. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE AS 6A, 7A E 8A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2343 DE 01-12-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |