BRPI0713272A2 - produtos terapêuticos específicos ao receptor na superfície de pan-células - Google Patents
produtos terapêuticos específicos ao receptor na superfície de pan-célulasInfo
- Publication number
- BRPI0713272A2 BRPI0713272A2 BRPI0713272A BRPI0713272A BRPI0713272A2 BR PI0713272 A2 BRPI0713272 A2 BR PI0713272A2 BR PI0713272 A BRPI0713272 A BR PI0713272A BR PI0713272 A BRPI0713272 A BR PI0713272A BR PI0713272 A2 BRPI0713272 A2 BR PI0713272A2
- Authority
- BR
- Brazil
- Prior art keywords
- receptor
- specific therapeutic
- therapeutic products
- pan cells
- pan
- Prior art date
Links
- 230000001225 therapeutic effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Heart & Thoracic Surgery (AREA)
- Microbiology (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Plant Pathology (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US81326006P | 2006-06-12 | 2006-06-12 | |
US84854206P | 2006-09-29 | 2006-09-29 | |
US87894107P | 2007-01-05 | 2007-01-05 | |
PCT/US2007/071041 WO2007146959A2 (en) | 2006-06-12 | 2007-06-12 | Pan-cell surface receptor- specific therapeutics |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0713272A2 true BRPI0713272A2 (pt) | 2017-05-02 |
Family
ID=38832799
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0713272A BRPI0713272A2 (pt) | 2006-06-12 | 2007-06-12 | produtos terapêuticos específicos ao receptor na superfície de pan-células |
Country Status (11)
Country | Link |
---|---|
US (1) | US20100055093A1 (pt) |
EP (1) | EP2044115A2 (pt) |
JP (1) | JP2009539412A (pt) |
KR (1) | KR20090031897A (pt) |
AU (1) | AU2007257683A1 (pt) |
BR (1) | BRPI0713272A2 (pt) |
CA (1) | CA2655205A1 (pt) |
IL (1) | IL195909A0 (pt) |
NZ (1) | NZ574093A (pt) |
SG (1) | SG172692A1 (pt) |
WO (1) | WO2007146959A2 (pt) |
Families Citing this family (60)
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CN101827860A (zh) * | 2007-10-16 | 2010-09-08 | 西福根有限公司 | 包含最佳化her1和her3多聚体的组合物及其使用方法 |
US20090162359A1 (en) | 2007-12-21 | 2009-06-25 | Christian Klein | Bivalent, bispecific antibodies |
JP2010006705A (ja) * | 2008-06-13 | 2010-01-14 | Atlas Antibodies Ab | Her2サブセット |
WO2010033249A2 (en) | 2008-09-22 | 2010-03-25 | Massachusetts Institute Of Technology | Compositions of and methods using ligand dimers |
EP2346525A4 (en) * | 2008-10-02 | 2012-05-09 | Celtaxsys Inc | METHODS OF MODULATION OF NEGATIVE CHIMOTAXIA OF IMMUNE CELLS |
US9676845B2 (en) | 2009-06-16 | 2017-06-13 | Hoffmann-La Roche, Inc. | Bispecific antigen binding proteins |
MX2012000991A (es) * | 2009-07-28 | 2012-03-16 | Ligacept Llc | Moleculas de union a ligandos de erbb de amplio espectro y metodos para su preparacion y utilizacion. |
EP2494046B1 (en) | 2009-10-30 | 2018-09-12 | Novartis AG | Universal fibronectin type iii bottom-side binding domain libraries |
ES2600879T3 (es) | 2009-11-13 | 2017-02-13 | Grifols Therapeutics Inc. | Preparaciones que contienen el factor de Von Willebrand (FvW) y procedimientos, kits y utilizaciones relacionados con las mismas |
RU2587619C2 (ru) | 2010-02-18 | 2016-06-20 | Дженентек, Инк. | Антагонисты неурегулина и применение их в лечении злокачественного новообразования |
US9029328B2 (en) | 2010-03-24 | 2015-05-12 | The Brigham And Women's Hospital, Inc. | Methods for cardioprotection and cardioregeneration with dimers of EGF family ligands |
AU2011283646B2 (en) | 2010-07-30 | 2015-07-09 | Novartis Ag | Fibronectin cradle molecules and libraries thereof |
JP6057896B2 (ja) | 2010-08-20 | 2017-01-11 | ノバルティス アーゲー | 上皮細胞増殖因子受容体3(her3)に対する抗体 |
WO2012047175A1 (en) * | 2010-10-05 | 2012-04-12 | Kemijski inštitut | Fusion polypeptides comprising tir and dimerization domain for modulation of tlr/innate immunity signaling |
WO2012103114A2 (en) * | 2011-01-24 | 2012-08-02 | Jason Hill | Therapeutic chimeric ligand binding proteins and methods for their use |
AR085404A1 (es) | 2011-02-28 | 2013-09-25 | Hoffmann La Roche | Proteinas de union a antigeno |
WO2012116927A1 (en) | 2011-02-28 | 2012-09-07 | F. Hoffmann-La Roche Ag | Monovalent antigen binding proteins |
CN102219860B (zh) * | 2011-05-20 | 2012-09-12 | 烟台荣昌生物工程有限公司 | FGFR-Fc融合蛋白及其用途 |
CN102219859B (zh) * | 2011-05-20 | 2012-09-12 | 烟台荣昌生物工程有限公司 | 拮抗血管新生诱导因子的融合蛋白及其用途 |
WO2012162418A1 (en) * | 2011-05-23 | 2012-11-29 | The University Of North Carolina At Chapel Hill | Methods and compositions for heterodimeric targeting ligands |
WO2012169822A2 (ko) * | 2011-06-10 | 2012-12-13 | 강원대학교산학협력단 | 암세포 증식 억제와 혈관신생 억제를 위한 융합 단백질 및 이를 포함한 항암 조성물 |
KR101397088B1 (ko) | 2011-06-10 | 2014-05-19 | 강원대학교산학협력단 | 암세포 증식 억제와 혈관신생 억제를 위한 융합 단백질 및 이를 포함한 항암 조성물 |
WO2013003652A1 (en) | 2011-06-28 | 2013-01-03 | Sea Lane Biotechnologies, Llc | Multispecific stacked variable domain binding proteins |
JP2013040148A (ja) * | 2011-08-19 | 2013-02-28 | Asahi Kasei Corp | シアリルオリゴ糖ペプチド固定化ビーズ |
CA2850667A1 (en) | 2011-10-04 | 2013-04-11 | Expression Pathology, Inc. | Srm/mrm assay for the receptor tyrosine-protein kinase erbb-4 protein (her4) |
EP2773659A2 (en) | 2011-10-31 | 2014-09-10 | Bristol-Myers Squibb Company | Fibronectin binding domains with reduced immunogenicity |
CN104105709A (zh) * | 2011-12-05 | 2014-10-15 | 诺华股份有限公司 | 抗her3的结构域ii的表皮生长因子受体3(her3)抗体 |
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EP2804624B1 (en) | 2012-01-19 | 2018-12-26 | Duke University | Vaccines against antigens involved in therapy resistance and methods of using same |
CA2869529A1 (en) | 2012-05-24 | 2013-11-28 | Raffaella CASTOLDI | Multispecific antibodies |
EP2727943A1 (en) | 2012-11-05 | 2014-05-07 | MAB Discovery GmbH | Trispecific antibodies against human EGFR, HER2 and HER3 |
EP2727942A1 (en) | 2012-11-05 | 2014-05-07 | MAB Discovery GmbH | Bispecific antibodies against human EGFR, HER2, and HER3 |
EP2914629A1 (en) | 2012-11-05 | 2015-09-09 | MAB Discovery GmbH | Method for the production of multispecific antibodies |
EP2727941A1 (en) | 2012-11-05 | 2014-05-07 | MAB Discovery GmbH | Method for the production of multispecific antibodies |
AU2013343667A1 (en) | 2012-11-08 | 2015-04-02 | F. Hoffmann-La Roche Ag | HER3 antigen binding proteins binding to the beta-hairpin of HER3 |
EA201500503A1 (ru) * | 2012-11-08 | 2015-10-30 | Ф.Хоффманн-Ля Рош Аг | Анти-her3/her4 антигенсвязывающие белки, связывающиеся с бета-шпилькой her3 и бета-шпилькой her4 |
RS59925B1 (sr) | 2013-07-05 | 2020-03-31 | H Lee Moffitt Cancer Center And Research Institute Inc | Rastvorljivi cd33 za lečenje mijelodisplastičnih sindroma (mds) |
JP6422956B2 (ja) | 2013-10-11 | 2018-11-14 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | 多重特異性ドメイン交換共通可変軽鎖抗体 |
JPWO2015099197A1 (ja) * | 2013-12-25 | 2017-03-23 | 国立大学法人佐賀大学 | 肺癌の検査方法 |
US20160331853A1 (en) * | 2014-01-21 | 2016-11-17 | The Trustees Of Columbia University In The City Of New York | Compositions for radiotherapy and uses thereof |
EP3143048B1 (en) | 2014-05-14 | 2019-08-28 | F. Hoffmann-La Roche AG | Anti-her3 antibodies binding to the beta-hairpin of her3 |
EP3166630A4 (en) | 2014-07-07 | 2018-03-28 | Duke University | Vaccines against an oncogenic isoform of esr1 and methods of using the same |
US20170196953A1 (en) | 2014-07-07 | 2017-07-13 | Duke University | VACCINES AGAINST AN ONCOGENIC ISOFORM OF HER2 (ErbB2) AND METHODS OF USING THE SAME |
CN107106666A (zh) | 2014-07-17 | 2017-08-29 | 布莱恩·J·赫尔尼奇 | 用于基于免疫的治疗的免疫原性mhcii类肽的鉴定 |
EP3316871A4 (en) | 2015-06-30 | 2019-02-20 | The Trustees of Columbia University in the City of New York | TALKED COMPOSITION AND USES THEREOF |
WO2017120576A1 (en) * | 2016-01-07 | 2017-07-13 | Duke University | Cancer vaccines and methods of delivery |
EP3490615A4 (en) * | 2016-07-27 | 2020-04-01 | The Trustees of Columbia University in the City of New York | GELBUND COMPOSITIONS FOR RADIATION THERAPY AND USES THEREOF |
US11224665B2 (en) | 2016-10-05 | 2022-01-18 | Duke University | Mitochondrial antiviral signaling (MAVS) protein compositions and methods of using the same |
US10487143B2 (en) | 2016-10-05 | 2019-11-26 | Duke University | Vaccines against HER3 antigens and methods of using the same |
EP3568474A1 (en) | 2017-01-10 | 2019-11-20 | Intrexon Corporation | Modulating expression of polypeptides via new gene switch expression systems |
US11617797B2 (en) | 2017-04-28 | 2023-04-04 | David T. Tran | Multi-targeted multi-valent ligand drug particles for the treatment and prevention of diseases and conditions |
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CN111406071B (zh) * | 2017-11-16 | 2024-01-16 | 成都硕德药业有限公司 | Pas化的vegfr/pdgfr融合蛋白及其在治疗中的用途 |
EP3710483A4 (en) | 2017-11-16 | 2021-10-20 | XL-protein GmbH | PASYLATED VEGFR / PDGFR FUSION PROTEINS AND THEIR USE IN THERAPY |
AU2018383096A1 (en) * | 2017-12-11 | 2020-06-11 | Medizinische Universitaet Wien | A method of producing a vaccine composition and uses thereof |
AR121035A1 (es) * | 2019-04-01 | 2022-04-13 | Lilly Co Eli | Compuestos de neuregulina-4 y métodos de uso |
WO2021207727A1 (en) * | 2020-04-10 | 2021-10-14 | Postsurgical Therapeutics, Inc. | Combinatorial targeted therapy methods |
CA3193273A1 (en) | 2020-08-27 | 2022-03-03 | Enosi Therapeutics Corporation | Methods and compositions to treat autoimmune diseases and cancer |
WO2023168426A1 (en) | 2022-03-03 | 2023-09-07 | Enosi Therapeutics Corporation | Compositions and cells containing mixtures of oligo-trap fusion proteins (ofps) and uses thereof |
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-
2007
- 2007-06-12 KR KR1020097000615A patent/KR20090031897A/ko not_active Application Discontinuation
- 2007-06-12 NZ NZ574093A patent/NZ574093A/en not_active IP Right Cessation
- 2007-06-12 EP EP07784419A patent/EP2044115A2/en not_active Withdrawn
- 2007-06-12 JP JP2009515614A patent/JP2009539412A/ja not_active Withdrawn
- 2007-06-12 AU AU2007257683A patent/AU2007257683A1/en not_active Abandoned
- 2007-06-12 BR BRPI0713272A patent/BRPI0713272A2/pt not_active IP Right Cessation
- 2007-06-12 WO PCT/US2007/071041 patent/WO2007146959A2/en active Application Filing
- 2007-06-12 SG SG2011041944A patent/SG172692A1/en unknown
- 2007-06-12 CA CA002655205A patent/CA2655205A1/en not_active Abandoned
- 2007-06-12 US US12/304,467 patent/US20100055093A1/en not_active Abandoned
-
2008
- 2008-12-11 IL IL195909A patent/IL195909A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
US20100055093A1 (en) | 2010-03-04 |
SG172692A1 (en) | 2011-07-28 |
KR20090031897A (ko) | 2009-03-30 |
WO2007146959A3 (en) | 2008-07-24 |
WO2007146959A2 (en) | 2007-12-21 |
JP2009539412A (ja) | 2009-11-19 |
CA2655205A1 (en) | 2007-12-21 |
AU2007257683A1 (en) | 2007-12-21 |
NZ574093A (en) | 2011-03-31 |
IL195909A0 (en) | 2011-08-01 |
EP2044115A2 (en) | 2009-04-08 |
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