BRPI0710649A2 - proteìnas quiméricas hipoalergênicas pertencentes à famìlia de transferência lipìdica de parietaria judaica para uso no tratamento de alergias - Google Patents

proteìnas quiméricas hipoalergênicas pertencentes à famìlia de transferência lipìdica de parietaria judaica para uso no tratamento de alergias Download PDF

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Publication number
BRPI0710649A2
BRPI0710649A2 BRPI0710649-1A BRPI0710649A BRPI0710649A2 BR PI0710649 A2 BRPI0710649 A2 BR PI0710649A2 BR PI0710649 A BRPI0710649 A BR PI0710649A BR PI0710649 A2 BRPI0710649 A2 BR PI0710649A2
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BR
Brazil
Prior art keywords
par
seq
chimeric protein
protein
allergy
Prior art date
Application number
BRPI0710649-1A
Other languages
English (en)
Portuguese (pt)
Inventor
Andrés Asturias Juan
Martinez Garate Alberto
Gonzales Rioja Roberto
Original Assignee
Bial Industrial Farmacéutica, S.A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bial Industrial Farmacéutica, S.A filed Critical Bial Industrial Farmacéutica, S.A
Publication of BRPI0710649A2 publication Critical patent/BRPI0710649A2/pt

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/35Allergens
    • A61K39/36Allergens from pollen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/577Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 tolerising response
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/62Insulins
    • C07K14/625Extraction from natural sources
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Botany (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pulmonology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
BRPI0710649-1A 2006-04-12 2007-04-11 proteìnas quiméricas hipoalergênicas pertencentes à famìlia de transferência lipìdica de parietaria judaica para uso no tratamento de alergias BRPI0710649A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ES200600955A ES2307381B1 (es) 2006-04-12 2006-04-12 Proteinas quimericas hipoalergenicas pertenecientes a la familia de transportadoras de lipidos de parietaria judaica utiles para el tratami ento de alergias.
ES200600955 2006-04-12
PCT/IB2007/001025 WO2007116316A1 (en) 2006-04-12 2007-04-11 Hypoallergenic chimeric proteins belonging to the lipid transfer family of parietaria judaica for use in the treatment of allergies

Publications (1)

Publication Number Publication Date
BRPI0710649A2 true BRPI0710649A2 (pt) 2011-08-23

Family

ID=38421459

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0710649-1A BRPI0710649A2 (pt) 2006-04-12 2007-04-11 proteìnas quiméricas hipoalergênicas pertencentes à famìlia de transferência lipìdica de parietaria judaica para uso no tratamento de alergias

Country Status (10)

Country Link
US (2) US8697083B2 (enExample)
EP (3) EP2392592B1 (enExample)
JP (3) JP5373597B2 (enExample)
CN (2) CN101421296B (enExample)
BR (1) BRPI0710649A2 (enExample)
CA (1) CA2646900C (enExample)
ES (2) ES2307381B1 (enExample)
MX (1) MX2008013050A (enExample)
PT (1) PT2007798E (enExample)
WO (1) WO2007116316A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2307381B1 (es) * 2006-04-12 2009-10-23 Bial Industrial Farmaceutica S.A. Proteinas quimericas hipoalergenicas pertenecientes a la familia de transportadoras de lipidos de parietaria judaica utiles para el tratami ento de alergias.
IT1395735B1 (it) * 2009-08-04 2012-10-19 Lofarma Spa Proteina ibrida ipoallergenica e suoi usi
RU2470298C2 (ru) * 2011-04-01 2012-12-20 Федеральное бюджетное учреждение науки "Уфимский научно-исследовательский институт медицины труда и экологии человека" (ФБУН "Уфимский НИИ медицины труда и экологии человека") Способ ранней (донозологической) диагностики развития сенсибилизации к аллергенам воздуха рабочей зоны птицеводческого комплекса

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10037759A1 (de) 2000-08-03 2002-07-04 Gruenenthal Gmbh Screeningverfahren
IT1317905B1 (it) 2000-09-11 2003-07-15 Consiglio Nazionale Ricerche Varianti di allergeni ns-ltps, loro usi e composizioni che lecomprendono.
IT1318690B1 (it) 2000-09-12 2003-08-27 Consiglio Nazionale Ricerche Varianti dell'allergene maggiore par j 2 di parietaria judaica.
US20030175312A1 (en) * 2000-11-16 2003-09-18 Alk-Abello A/S Novel mutant allergens
EP1221317A1 (en) * 2000-12-28 2002-07-10 SHAN-Beteiligungsgesellschaft m.b.H. Vaccines containing hybrid polypeptides consisting of at least two different allergenic proteins
JP4538192B2 (ja) * 2001-05-01 2010-09-08 ザ リージェンツ オブ ザ ユニバーシティー オブ カリフォルニア 免疫疾患を治療するための融合分子及び方法
US7265208B2 (en) * 2001-05-01 2007-09-04 The Regents Of The University Of California Fusion molecules and treatment of IgE-mediated allergic diseases
ATE307141T1 (de) 2003-01-21 2005-11-15 Biomay Prod & Handel Verfahren zur vorbereitung von hypoallergenen mosaikproteine
ITRM20030247A1 (it) * 2003-05-20 2004-11-21 Bonura Angela Varianti ipoallergeniche degli allergeni maggiori
ITRM20040103A1 (it) * 2004-02-27 2004-05-27 Consiglio Nazionale Ricerche Proteine di fusione comprendenti allergeni della famiglia delle ns-ltps, loro usi e composizioni farmaceutiche che le comprendono.
AT501101B1 (de) * 2004-12-02 2008-01-15 Biomay Ag Protein-allergen-derivat
ES2307381B1 (es) * 2006-04-12 2009-10-23 Bial Industrial Farmaceutica S.A. Proteinas quimericas hipoalergenicas pertenecientes a la familia de transportadoras de lipidos de parietaria judaica utiles para el tratami ento de alergias.

Also Published As

Publication number Publication date
CA2646900A1 (en) 2007-10-18
US20090304727A1 (en) 2009-12-10
US8697083B2 (en) 2014-04-15
EP2007798B1 (en) 2015-09-30
ES2550705T3 (es) 2015-11-11
CN101421296B (zh) 2013-01-02
CN101421296A (zh) 2009-04-29
MX2008013050A (es) 2009-01-14
PT2007798E (pt) 2015-11-13
JP2009533046A (ja) 2009-09-17
JP5373597B2 (ja) 2013-12-18
JP2013233149A (ja) 2013-11-21
CN103059140B (zh) 2016-09-28
JP2016104796A (ja) 2016-06-09
EP2392592B1 (en) 2016-12-14
CA2646900C (en) 2016-06-14
ES2307381R (es) 2008-12-01
CN103059140A (zh) 2013-04-24
EP2392592A1 (en) 2011-12-07
JP6148088B2 (ja) 2017-06-14
EP2007798A1 (en) 2008-12-31
EP2363409A1 (en) 2011-09-07
ES2307381B1 (es) 2009-10-23
US20140286972A1 (en) 2014-09-25
ES2307381A2 (es) 2008-11-16
WO2007116316A1 (en) 2007-10-18
US9522939B2 (en) 2016-12-20

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B25G Requested change of headquarter approved

Owner name: BIAL INDUSTRIAL FARMACEUTICA, S.A (ES)

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]