BRPI0618217A2 - usos de anticorpos anti-cd40 - Google Patents
usos de anticorpos anti-cd40 Download PDFInfo
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- BRPI0618217A2 BRPI0618217A2 BRPI0618217-8A BRPI0618217A BRPI0618217A2 BR PI0618217 A2 BRPI0618217 A2 BR PI0618217A2 BR PI0618217 A BRPI0618217 A BR PI0618217A BR PI0618217 A2 BRPI0618217 A2 BR PI0618217A2
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- A—HUMAN NECESSITIES
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- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P37/00—Drugs for immunological or allergic disorders
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- A—HUMAN NECESSITIES
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- A61P37/00—Drugs for immunological or allergic disorders
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- A—HUMAN NECESSITIES
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- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2887—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/77—Internalization into the cell
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
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- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
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- General Chemical & Material Sciences (AREA)
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- Rheumatology (AREA)
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- Dermatology (AREA)
- Endocrinology (AREA)
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- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73258005P | 2005-11-01 | 2005-11-01 | |
| US60/732.580 | 2005-11-01 | ||
| PCT/US2006/042601 WO2007053661A2 (en) | 2005-11-01 | 2006-11-01 | Uses of anti-cd40 antibodies |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0618217A2 true BRPI0618217A2 (pt) | 2011-08-23 |
Family
ID=38006484
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0618217-8A BRPI0618217A2 (pt) | 2005-11-01 | 2006-11-01 | usos de anticorpos anti-cd40 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20090202531A1 (enExample) |
| EP (1) | EP1957538B1 (enExample) |
| JP (1) | JP2009513712A (enExample) |
| KR (1) | KR101395005B1 (enExample) |
| CN (1) | CN101351478A (enExample) |
| AU (1) | AU2006308860B2 (enExample) |
| BR (1) | BRPI0618217A2 (enExample) |
| CA (1) | CA2627891A1 (enExample) |
| ES (1) | ES2428089T3 (enExample) |
| IL (1) | IL191117A (enExample) |
| RU (1) | RU2442606C2 (enExample) |
| WO (1) | WO2007053661A2 (enExample) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
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| DE10303974A1 (de) | 2003-01-31 | 2004-08-05 | Abbott Gmbh & Co. Kg | Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung |
| AU2006308606C1 (en) | 2005-11-01 | 2013-07-25 | Novartis Ag | Uses of anti-CD40 antibodies |
| KR20080090408A (ko) | 2005-11-30 | 2008-10-08 | 아보트 러보러터리즈 | 항-Ａβ 글로불로머 항체, 이의 항원-결합 잔기, 상응하는하이브리도마, 핵산, 벡터, 숙주 세포, 당해 항체의 제조방법, 당해 항체를 포함하는 조성물, 당해 항체의 용도 및당해 항체의 사용 방법 |
| SG10201706600VA (en) | 2005-11-30 | 2017-09-28 | Abbvie Inc | Monoclonal antibodies and uses thereof |
| US8455626B2 (en) | 2006-11-30 | 2013-06-04 | Abbott Laboratories | Aβ conformer selective anti-aβ globulomer monoclonal antibodies |
| WO2008104386A2 (en) | 2007-02-27 | 2008-09-04 | Abbott Gmbh & Co. Kg | Method for the treatment of amyloidoses |
| EP2077281A1 (en) * | 2008-01-02 | 2009-07-08 | Bergen Teknologioverforing AS | Anti-CD20 antibodies or fragments thereof for the treatment of chronic fatigue syndrome |
| JP5828151B6 (ja) | 2009-01-06 | 2018-09-19 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | アテローム性動脈硬化の処置のためのｂ細胞枯渇剤 |
| CA2767616A1 (en) | 2009-07-09 | 2011-01-13 | The Scripps Research Institute | Gene expression profiles associated with chronic allograft nephropathy |
| EP2558494B1 (en) | 2010-04-15 | 2018-05-23 | AbbVie Inc. | Amyloid-beta binding proteins |
| RU2441023C1 (ru) * | 2010-07-15 | 2012-01-27 | Олег Ильич Эпштейн | Лекарственное средство для лечения рассеянного склероза и способ лечения рассеянного склероза |
| RU2509573C2 (ru) * | 2010-07-27 | 2014-03-20 | Олег Ильич Эпштейн | Лекарственное средство для лечения рассеянного склероза и способ лечения рассеянного склероза |
| US9062101B2 (en) | 2010-08-14 | 2015-06-23 | AbbVie Deutschland GmbH & Co. KG | Amyloid-beta binding proteins |
| AR083847A1 (es) | 2010-11-15 | 2013-03-27 | Novartis Ag | Variantes de fc (fragmento constante) silenciosas de los anticuerpos anti-cd40 |
| WO2012075111A1 (en) | 2010-11-30 | 2012-06-07 | Novartis Ag | Uses of anti-cd40 antibodies in combination therapy for b cell-related cancers |
| HUE065915T2 (hu) | 2011-03-11 | 2024-06-28 | Beth Israel Deaconess Medical Ct Inc | Anti-CD40 antitestek és alkalmazásaik |
| CN103635488B (zh) | 2011-04-29 | 2016-12-14 | 埃派斯进有限公司 | 抗-cd40抗体及其使用方法 |
| CA2839542A1 (en) * | 2011-06-17 | 2012-12-20 | Constitution Medical, Inc. | Fixative and staining solutions |
| US20140004131A1 (en) | 2012-05-04 | 2014-01-02 | Novartis Ag | Antibody formulation |
| EP2914627B1 (en) | 2012-10-30 | 2021-04-07 | Apexigen, Inc. | Anti-cd40 antibodies and methods of use |
| ES3040431T3 (en) | 2014-03-12 | 2025-10-31 | Yeda Res & Dev | Reducing systemic regulatory t cell levels or activity for treatment of disease and injury of the cns |
| CN108025068A (zh) * | 2014-03-12 | 2018-05-11 | 耶达研究与开发有限公司 | 降低系统性调节性t细胞水平或活性来治疗cns的疾病和损伤 |
| US10618963B2 (en) | 2014-03-12 | 2020-04-14 | Yeda Research And Development Co. Ltd | Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS |
| US10519237B2 (en) | 2014-03-12 | 2019-12-31 | Yeda Research And Development Co. Ltd | Reducing systemic regulatory T cell levels or activity for treatment of disease and injury of the CNS |
| US10443100B2 (en) | 2014-05-22 | 2019-10-15 | The Scripps Research Institute | Gene expression profiles associated with sub-clinical kidney transplant rejection |
| US11104951B2 (en) | 2014-05-22 | 2021-08-31 | The Scripps Research Institute | Molecular signatures for distinguishing liver transplant rejections or injuries |
| AU2015360502A1 (en) | 2014-12-10 | 2017-06-29 | Regents Of The University Of Minnesota | Genetically modified cells, tissues, and organs for treating disease |
| UY36692A (es) | 2015-05-29 | 2016-12-30 | Abbvie Inc | Anticuerpos anti-cd40 y usos de los mismos |
| EP3307322B1 (en) | 2015-09-04 | 2021-02-17 | Primatope Therapeutics Inc. | Humanized anti-cd40 antibodies and uses thereof |
| MX2018003905A (es) * | 2015-09-30 | 2018-09-06 | Janssen Biotech Inc | Anticuerpos agonistas que se unen específicamente a cd40 humana y métodos de uso. |
| BR112018076260A2 (pt) | 2016-06-20 | 2019-03-26 | Kymab Limited | anticorpo ou fragmento do mesmo que se liga especificamente a hpd-l1, anticorpo biespecífico ou proteína de fusão, uso de um anticorpo ou fragmento, método, composição farmacêutica, método de modulação, método de inibição, método de tratamento, ácido nucleico, vetor, hospedeiro e imunocitocina |
| US11242397B2 (en) * | 2017-06-01 | 2022-02-08 | Pb Immune Therapeutics Inc. | Anti-CD40 antibody and methods for blocking CD40-CD40L signaling |
| KR20210035805A (ko) | 2018-06-15 | 2021-04-01 | 플래그쉽 파이어니어링 이노베이션스 브이, 인크. | 세포후 신호전달 인자의 조절을 통한 면역 활성의 증가 |
| MA55805A (fr) | 2019-05-03 | 2022-03-09 | Flagship Pioneering Innovations V Inc | Métodes de modulation de l'activité immunitaire |
| US20230114107A1 (en) | 2019-12-17 | 2023-04-13 | Flagship Pioneering Innovations V, Inc. | Combination anti-cancer therapies with inducers of iron-dependent cellular disassembly |
| US20230355804A1 (en) | 2020-06-29 | 2023-11-09 | Flagship Pioneering Innovations V, Inc. | Viruses engineered to promote thanotransmission and their use in treating cancer |
| WO2022120038A1 (en) * | 2020-12-02 | 2022-06-09 | Albert Einstein College Of Medicine | Method for predicting patient response to cd40-targeted therapies |
| CA3214085A1 (en) | 2021-03-31 | 2022-10-06 | Darby Rye Schmidt | Thanotransmission polypeptides and their use in treating cancer |
| KR20240026507A (ko) | 2021-06-29 | 2024-02-28 | 플래그쉽 파이어니어링 이노베이션스 브이, 인크. | 타노트랜스미션을 촉진시키도록 엔지니어링된 면역 세포 및 이의 용도 |
| US20240343817A1 (en) * | 2021-07-14 | 2024-10-17 | Staidson (Beijing) Biopharmaceuticals Co., Ltd. | Antibody that specifically recognizes cd40 and application thereof |
| US12234294B2 (en) | 2021-11-05 | 2025-02-25 | Kiniksa Pharmaceuticals, Gmbh | Pharmaceutical composition of a humanized anti-CD40 antibody |
| WO2024077191A1 (en) | 2022-10-05 | 2024-04-11 | Flagship Pioneering Innovations V, Inc. | Nucleic acid molecules encoding trif and additionalpolypeptides and their use in treating cancer |
| WO2024151687A1 (en) | 2023-01-09 | 2024-07-18 | Flagship Pioneering Innovations V, Inc. | Genetic switches and their use in treating cancer |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6136310A (en) * | 1991-07-25 | 2000-10-24 | Idec Pharmaceuticals Corporation | Recombinant anti-CD4 antibodies for human therapy |
| US5874082A (en) * | 1992-07-09 | 1999-02-23 | Chiron Corporation | Humanized anti-CD40 monoclonal antibodies and fragments capable of blocking B cell proliferation |
| JP3675819B2 (ja) * | 1993-10-01 | 2005-07-27 | イミュネックス・コーポレーション | Ｃｄ４０に対する抗体 |
| US6946129B1 (en) * | 1999-06-08 | 2005-09-20 | Seattle Genetics, Inc. | Recombinant anti-CD40 antibody and uses thereof |
| US7063845B2 (en) * | 2000-04-28 | 2006-06-20 | Gemini Science, Inc. | Human anti-CD40 antibodies |
| US7858300B2 (en) * | 2001-10-19 | 2010-12-28 | Centre Hospitalier Regional Et Universitaire De Tours | Methods and compositions to evaluate antibody treatment response |
| HRP20090325T1 (en) * | 2003-04-09 | 2009-07-31 | Genentech | Therapy of autoimmune disease in a patient with an inadequate response to a tnf-alpha inhibitor |
| RS53073B (sr) * | 2003-11-04 | 2014-04-30 | Novartis Vaccines And Diagnostics Inc. | Upotreba antagonističkih anti-cd40 monoklonska antitela |
| SI1682177T1 (sl) * | 2003-11-04 | 2010-12-31 | Novartis Vaccines & Diagnostic | Uporaba antagonističnih anti-CD40 protiteles za zdravljenje kronične limfocitne levkemije |
| DK1684805T3 (da) * | 2003-11-04 | 2010-10-04 | Novartis Vaccines & Diagnostic | Anvendelse af antagonist anti-CD40-monoklonale antistoffer til behandling af multipel myeloma |
| PT1684869E (pt) * | 2003-11-04 | 2011-09-16 | Novartis Vaccines & Diagnostic | Métodos de terapêutica para cancros relacionados com células b |
| EP2301575A1 (en) * | 2003-11-04 | 2011-03-30 | Novartis Vaccines and Diagnostics, Inc. | Methods of therapy for solid tumors expressing the CD40 cell-surface antigen |
| US20070231813A1 (en) * | 2004-06-01 | 2007-10-04 | Centre Hospitalier Regional Et Universitaire De Tours | Fcgr3a Gebotype and Methods for Evaluating Treatment Response to Non-Depleting Antibodies |
| US20080057070A1 (en) * | 2004-11-04 | 2008-03-06 | Chiron Corporation | Antagonist Anti-Cd40 Monoclonal Antibodies and Methods for Their Use |
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- 2006-11-01 WO PCT/US2006/042601 patent/WO2007053661A2/en not_active Ceased
- 2006-11-01 CA CA002627891A patent/CA2627891A1/en not_active Abandoned
- 2006-11-01 EP EP06836747.3A patent/EP1957538B1/en active Active
- 2006-11-01 KR KR1020087012998A patent/KR101395005B1/ko not_active Expired - Fee Related
- 2006-11-01 JP JP2008538984A patent/JP2009513712A/ja active Pending
- 2006-11-01 BR BRPI0618217-8A patent/BRPI0618217A2/pt not_active IP Right Cessation
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- 2006-11-01 AU AU2006308860A patent/AU2006308860B2/en not_active Ceased
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Also Published As
| Publication number | Publication date |
|---|---|
| CA2627891A1 (en) | 2007-05-10 |
| AU2006308860A1 (en) | 2007-05-10 |
| AU2006308860B2 (en) | 2012-01-12 |
| IL191117A (en) | 2013-05-30 |
| ES2428089T3 (es) | 2013-11-05 |
| RU2008121899A (ru) | 2009-12-10 |
| HK1122579A1 (en) | 2009-05-22 |
| EP1957538B1 (en) | 2013-05-22 |
| RU2442606C2 (ru) | 2012-02-20 |
| WO2007053661A3 (en) | 2007-11-01 |
| KR20080100806A (ko) | 2008-11-19 |
| EP1957538A2 (en) | 2008-08-20 |
| US20090202531A1 (en) | 2009-08-13 |
| IL191117A0 (en) | 2008-12-29 |
| JP2009513712A (ja) | 2009-04-02 |
| WO2007053661A2 (en) | 2007-05-10 |
| KR101395005B1 (ko) | 2014-05-21 |
| CN101351478A (zh) | 2009-01-21 |
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| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2330 DE 01-09-2015 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013. |