BRPI0614608A2 - análogos de camptotecina, um processo para a preparação dos mesmos e composições farmacêuticas que contêm os ditos compostos - Google Patents
análogos de camptotecina, um processo para a preparação dos mesmos e composições farmacêuticas que contêm os ditos compostosInfo
- Publication number
- BRPI0614608A2 BRPI0614608A2 BRPI0614608A BRPI0614608A BRPI0614608A2 BR PI0614608 A2 BRPI0614608 A2 BR PI0614608A2 BR PI0614608 A BRPI0614608 A BR PI0614608A BR PI0614608 A BRPI0614608 A BR PI0614608A BR PI0614608 A2 BRPI0614608 A2 BR PI0614608A2
- Authority
- BR
- Brazil
- Prior art keywords
- compounds
- preparation
- pharmaceutical compositions
- compositions containing
- camptothecin analogues
- Prior art date
Links
- VSJKWCGYPAHWDS-FQEVSTJZSA-N camptothecin Chemical class C1=CC=C2C=C(CN3C4=CC5=C(C3=O)COC(=O)[C@]5(O)CC)C4=NC2=C1 VSJKWCGYPAHWDS-FQEVSTJZSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0508364A FR2889527A1 (fr) | 2005-08-05 | 2005-08-05 | Nouveaux composes analogues de la camptothecine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
PCT/FR2006/001901 WO2007017585A2 (fr) | 2005-08-05 | 2006-08-04 | Nouveaux composes analogues de la camptothecine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0614608A2 true BRPI0614608A2 (pt) | 2016-11-16 |
Family
ID=36216903
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0614608A BRPI0614608A2 (pt) | 2005-08-05 | 2006-08-04 | análogos de camptotecina, um processo para a preparação dos mesmos e composições farmacêuticas que contêm os ditos compostos |
Country Status (19)
Country | Link |
---|---|
US (1) | US20100168149A1 (fr) |
EP (1) | EP1910377A2 (fr) |
JP (1) | JP2009503039A (fr) |
KR (1) | KR20080032007A (fr) |
CN (1) | CN101238133A (fr) |
AR (1) | AR056189A1 (fr) |
AU (1) | AU2006277863A1 (fr) |
BR (1) | BRPI0614608A2 (fr) |
CA (1) | CA2617957C (fr) |
EA (1) | EA014689B1 (fr) |
FR (1) | FR2889527A1 (fr) |
GE (1) | GEP20115243B (fr) |
MA (1) | MA29653B1 (fr) |
MX (1) | MX2008001560A (fr) |
MY (1) | MY150497A (fr) |
NO (1) | NO20081169L (fr) |
UA (1) | UA95253C2 (fr) |
WO (1) | WO2007017585A2 (fr) |
ZA (1) | ZA200801991B (fr) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2889528B1 (fr) * | 2005-08-05 | 2007-09-07 | Servier Lab | Nouveaux composes analogues de la camptothecine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
AU2014216178B2 (en) | 2013-02-15 | 2018-06-28 | KALA BIO, Inc. | Therapeutic compounds and uses thereof |
US9688688B2 (en) | 2013-02-20 | 2017-06-27 | Kala Pharmaceuticals, Inc. | Crystalline forms of 4-((4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-6-methoxyquinazolin-7-yl)oxy)-1-(2-oxa-7-azaspiro[3.5]nonan-7-yl)butan-1-one and uses thereof |
EP3763710A1 (fr) | 2013-02-20 | 2021-01-13 | Kala Pharmaceuticals, Inc. | Composés thérapeutiques et leurs utilisations |
US9890173B2 (en) | 2013-11-01 | 2018-02-13 | Kala Pharmaceuticals, Inc. | Crystalline forms of therapeutic compounds and uses thereof |
KR20160099084A (ko) | 2013-11-01 | 2016-08-19 | 칼라 파마슈티컬스, 인크. | 치료 화합물의 결정질 형태 및 그의 용도 |
CN106188079A (zh) * | 2016-07-09 | 2016-12-07 | 兰州大学 | 喜树碱7‑位哌嗪硫脲类化合物、制备方法和用途 |
AU2017324251A1 (en) | 2016-09-08 | 2019-03-21 | Kala Pharmaceuticals, Inc. | Crystalline forms of therapeutic compounds and uses thereof |
US10392399B2 (en) | 2016-09-08 | 2019-08-27 | Kala Pharmaceuticals, Inc. | Crystalline forms of therapeutic compounds and uses thereof |
CA3036336A1 (fr) | 2016-09-08 | 2018-03-15 | Kala Pharmaceuticals, Inc. | Formes cristallines de composes therapeutiques et leurs utilisations |
CN110357897A (zh) * | 2019-07-26 | 2019-10-22 | 上海健康医学院 | 一种具有抗肿瘤活性的喜树碱衍生物及其制备方法和应用 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6111107A (en) * | 1997-11-20 | 2000-08-29 | Enzon, Inc. | High yield method for stereoselective acylation of tertiary alcohols |
US6699876B2 (en) * | 1999-11-18 | 2004-03-02 | Les Laboratoires Servier | Camptothecin analogue compounds |
FR2801309B1 (fr) * | 1999-11-18 | 2002-01-04 | Adir | Nouveaux composes analogues de la camptothecine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
US6403604B1 (en) * | 2001-03-01 | 2002-06-11 | California Pacific Medical Center | Nitrogen-based camptothecin derivatives |
WO2003101998A1 (fr) * | 2002-06-03 | 2003-12-11 | California Pacific Medical Center | Derives azotes d'homo-camptothecine |
CN100443486C (zh) * | 2002-09-11 | 2008-12-17 | 中国医学科学院药物研究所 | 7-酯化和7,20-双酯化的喜树碱衍生物及其制法和其药物组合物与用途 |
FR2889528B1 (fr) * | 2005-08-05 | 2007-09-07 | Servier Lab | Nouveaux composes analogues de la camptothecine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
-
2005
- 2005-08-05 FR FR0508364A patent/FR2889527A1/fr active Pending
-
2006
- 2006-04-08 UA UAA200802668A patent/UA95253C2/ru unknown
- 2006-08-03 MY MYPI20063757 patent/MY150497A/en unknown
- 2006-08-04 JP JP2008524549A patent/JP2009503039A/ja active Pending
- 2006-08-04 ZA ZA200801991A patent/ZA200801991B/xx unknown
- 2006-08-04 EP EP06794288A patent/EP1910377A2/fr not_active Withdrawn
- 2006-08-04 EA EA200800393A patent/EA014689B1/ru not_active IP Right Cessation
- 2006-08-04 CN CNA2006800286572A patent/CN101238133A/zh active Pending
- 2006-08-04 CA CA2617957A patent/CA2617957C/fr not_active Expired - Fee Related
- 2006-08-04 BR BRPI0614608A patent/BRPI0614608A2/pt not_active IP Right Cessation
- 2006-08-04 WO PCT/FR2006/001901 patent/WO2007017585A2/fr active Application Filing
- 2006-08-04 MX MX2008001560A patent/MX2008001560A/es active IP Right Grant
- 2006-08-04 AR ARP060103405A patent/AR056189A1/es unknown
- 2006-08-04 KR KR1020087005342A patent/KR20080032007A/ko not_active Application Discontinuation
- 2006-08-04 AU AU2006277863A patent/AU2006277863A1/en not_active Abandoned
- 2006-08-04 GE GEAP200610531A patent/GEP20115243B/en unknown
- 2006-08-04 US US11/990,065 patent/US20100168149A1/en not_active Abandoned
-
2008
- 2008-01-28 MA MA30610A patent/MA29653B1/fr unknown
- 2008-03-05 NO NO20081169A patent/NO20081169L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
US20100168149A1 (en) | 2010-07-01 |
EA200800393A1 (ru) | 2008-08-29 |
FR2889527A1 (fr) | 2007-02-09 |
CA2617957C (fr) | 2011-09-20 |
UA95253C2 (ru) | 2011-07-25 |
CA2617957A1 (fr) | 2007-02-15 |
ZA200801991B (en) | 2009-08-26 |
WO2007017585A3 (fr) | 2007-04-12 |
AR056189A1 (es) | 2007-09-26 |
WO2007017585A2 (fr) | 2007-02-15 |
MA29653B1 (fr) | 2008-07-01 |
GEP20115243B (en) | 2011-06-27 |
KR20080032007A (ko) | 2008-04-11 |
MY150497A (en) | 2014-01-30 |
AU2006277863A1 (en) | 2007-02-15 |
CN101238133A (zh) | 2008-08-06 |
EA014689B1 (ru) | 2010-12-30 |
NO20081169L (no) | 2008-03-05 |
JP2009503039A (ja) | 2009-01-29 |
MX2008001560A (es) | 2008-02-15 |
EP1910377A2 (fr) | 2008-04-16 |
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Legal Events
Date | Code | Title | Description |
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B06G | Technical and formal requirements: other requirements [chapter 6.7 patent gazette] |
Free format text: SOLICITA-SE A REGULARIZACAO DA PROCURACAO, UMA VEZ QUE BASEADO NO ARTIGO 216 1O DA LPI, O DOCUMENTO DE PROCURACAO DEVE SER APRESENTADO NO ORIGINAL, TRASLADO OU FOTOCOPIA AUTENTICADA. |
|
B11Z | Dismissal: petition dismissal - article 216, par 2 of industrial property law |
Free format text: REFERENTE A PETICAO NO 20080016855/RJ DE 01/02/2008. |
|
B11M | Decision cancelled [chapter 11.13 patent gazette] |
Free format text: O DESPACHO 11.6.1 ESTA SENDO ANULADO TENDO POR BASE A DETERMINACAO DO DIRETOR DE PATENTES, A QUAL E CALCADA NO PARECER NO 0003-2014 AGU/PGF/PFE/INPI/COOPHI-LBC-1.0. |
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B06H | Technical and formal requirements: requirement cancelled [chapter 6.8 patent gazette] | ||
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] | ||
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |