BRPI0612440A2 - composição farmacêutica e uso de um profármaco de anfetamina - Google Patents

composição farmacêutica e uso de um profármaco de anfetamina Download PDF

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Publication number
BRPI0612440A2
BRPI0612440A2 BRPI0612440-2A BRPI0612440A BRPI0612440A2 BR PI0612440 A2 BRPI0612440 A2 BR PI0612440A2 BR PI0612440 A BRPI0612440 A BR PI0612440A BR PI0612440 A2 BRPI0612440 A2 BR PI0612440A2
Authority
BR
Brazil
Prior art keywords
amphetamine
lysine
composition according
bioavailability
auc
Prior art date
Application number
BRPI0612440-2A
Other languages
English (en)
Portuguese (pt)
Inventor
Travis Mickle
Suma Krishnan
Barney Bishop
James Scott Moncrief
Cristopher Lauderback
Rob Oberlender
Thomas Piccariello
Original Assignee
New River Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by New River Pharmaceuticals Inc filed Critical New River Pharmaceuticals Inc
Publication of BRPI0612440A2 publication Critical patent/BRPI0612440A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/542—Carboxylic acids, e.g. a fatty acid or an amino acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hospice & Palliative Care (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Addiction (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
BRPI0612440-2A 2005-04-08 2006-04-10 composição farmacêutica e uso de um profármaco de anfetamina BRPI0612440A2 (pt)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US66938505P 2005-04-08 2005-04-08
US66938605P 2005-04-08 2005-04-08
US60/669,385 2005-04-08
US60/669,386 2005-04-08
US68117005P 2005-05-16 2005-05-16
US60/681,170 2005-05-16
US75654806P 2006-01-06 2006-01-06
US60/756,548 2006-01-06
US75995806P 2006-01-19 2006-01-19
US60/759,958 2006-01-19
PCT/US2006/013221 WO2006121552A2 (en) 2005-04-08 2006-04-10 Abuse-resistant amphetamine prodrugs

Publications (1)

Publication Number Publication Date
BRPI0612440A2 true BRPI0612440A2 (pt) 2010-11-23

Family

ID=37397039

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0612440-2A BRPI0612440A2 (pt) 2005-04-08 2006-04-10 composição farmacêutica e uso de um profármaco de anfetamina

Country Status (6)

Country Link
EP (1) EP1865980A4 (enExample)
JP (1) JP2008535860A (enExample)
BR (1) BRPI0612440A2 (enExample)
CA (1) CA2603873A1 (enExample)
MX (1) MX2007012507A (enExample)
WO (1) WO2006121552A2 (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8318813B2 (en) 2007-09-13 2012-11-27 Lcs Group, Llc Method of treating binge eating disorder
WO2010042120A1 (en) 2008-10-09 2010-04-15 Archimica, Inc. Process for the synthesis of amphetamine derivatives
GB201002612D0 (en) * 2010-02-16 2010-03-31 Jagotec Ag Improvements in or relating to organic compounds
WO2014002039A1 (en) * 2012-06-27 2014-01-03 Shire Ag Amphetamine prodrugs
US11879019B2 (en) 2016-12-19 2024-01-23 The Regents Of The University Of California Dual-enzyme responsive peptides
EP3554548A4 (en) 2016-12-19 2020-08-19 The Regents of The University of California NON-CRUSHABLE PILL FORMULATIONS
DK3459538T3 (da) 2017-09-20 2020-08-03 Sandoz Ag Krystallinske salte af et dextroamfetamin-prodrug
GB2571696B (en) 2017-10-09 2020-05-27 Compass Pathways Ltd Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced
KR20220008824A (ko) 2019-04-17 2022-01-21 컴퍼스 패쓰파인더 리미티드 실로시빈으로 불안 장애, 두통 장애 및 섭식 장애를 치료하는 방법
EP4098248A1 (en) * 2019-12-30 2022-12-07 Labomed Pharmaceutical Company S.A. Oral solutions comprising lisdexamfetamine salts
AU2021382158C1 (en) 2020-11-18 2026-05-07 Definium Therapeutics US, Inc. Mdma prodrugs to assist psychotherapy
WO2023111325A1 (en) 2021-12-16 2023-06-22 Labomed Pharmaceutical Company S.A. Container comprising a lisdexamfetamine containing oral solution
WO2024023367A1 (en) 2022-07-29 2024-02-01 Labomed Pharmaceutical Company S.A. Lisdexamfetamine containing oral solution
EP4768024A1 (en) 2024-12-24 2026-07-01 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi MINI-TABLETS IN CAPSULE FORMULATIONS OF LISDEXAMFOETAMINE DIMESYLATE
WO2026142600A1 (en) 2024-12-24 2026-07-02 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi A capsule formulation of lisdexamfetamine dimesylate
WO2026142601A1 (en) 2024-12-24 2026-07-02 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Capsule formulations of lisdexamfetamine dimesylate

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3878187A (en) * 1972-09-11 1975-04-15 Syva Co Polypeptide derivatives of amphetamine and analogs for immunoassays
US6384020B1 (en) * 1999-07-14 2002-05-07 Shire Laboratories, Inc. Rapid immediate release oral dosage form
US7297346B2 (en) * 2001-05-25 2007-11-20 Cephalon Inc. Pharmaceutical formulations of modafinil
US7105486B2 (en) * 2002-02-22 2006-09-12 New River Pharmaceuticals Inc. Abuse-resistant amphetamine compounds
EA008864B1 (ru) * 2003-09-30 2007-08-31 Нью Ривер Фармасьютикалз Инк. Фармацевтические композиции для предотвращения передозировки или неправильного употребления лекарственных средств

Also Published As

Publication number Publication date
MX2007012507A (es) 2008-03-11
CA2603873A1 (en) 2006-11-16
EP1865980A4 (en) 2009-11-11
WO2006121552A3 (en) 2007-07-05
JP2008535860A (ja) 2008-09-04
EP1865980A2 (en) 2007-12-19
WO2006121552A9 (en) 2007-03-08
WO2006121552A2 (en) 2006-11-16

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Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: SHIRE LLC (US)

Free format text: TRANSFERIDO POR INCORPORACAO DE: NEW RIVER PHARMACEUTICALS INC.

B08F Application fees: dismissal - article 86 of industrial property law

Free format text: REFERENTE A 6A ANUIDADE.

B08H Application fees: decision cancelled

Free format text: REFERENTE AO 8.6 NA RPI 2161 NA DATA 05/06/2012.

B10A Cessation: cessation confirmed

Free format text: HOMOLOGADA A DESISTENCIA DO PEDIDO, SOLICITADA ATRAVES DA PETICAO NO 018120008917/SP DE 21/03/2012.