BRPI0612440A2 - composição farmacêutica e uso de um profármaco de anfetamina - Google Patents
composição farmacêutica e uso de um profármaco de anfetamina Download PDFInfo
- Publication number
- BRPI0612440A2 BRPI0612440A2 BRPI0612440-2A BRPI0612440A BRPI0612440A2 BR PI0612440 A2 BRPI0612440 A2 BR PI0612440A2 BR PI0612440 A BRPI0612440 A BR PI0612440A BR PI0612440 A2 BRPI0612440 A2 BR PI0612440A2
- Authority
- BR
- Brazil
- Prior art keywords
- amphetamine
- lysine
- composition according
- bioavailability
- auc
- Prior art date
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- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/542—Carboxylic acids, e.g. a fatty acid or an amino acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Child & Adolescent Psychology (AREA)
- Addiction (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US66938505P | 2005-04-08 | 2005-04-08 | |
| US66938605P | 2005-04-08 | 2005-04-08 | |
| US60/669,385 | 2005-04-08 | ||
| US60/669,386 | 2005-04-08 | ||
| US68117005P | 2005-05-16 | 2005-05-16 | |
| US60/681,170 | 2005-05-16 | ||
| US75654806P | 2006-01-06 | 2006-01-06 | |
| US60/756,548 | 2006-01-06 | ||
| US75995806P | 2006-01-19 | 2006-01-19 | |
| US60/759,958 | 2006-01-19 | ||
| PCT/US2006/013221 WO2006121552A2 (en) | 2005-04-08 | 2006-04-10 | Abuse-resistant amphetamine prodrugs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0612440A2 true BRPI0612440A2 (pt) | 2010-11-23 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0612440-2A BRPI0612440A2 (pt) | 2005-04-08 | 2006-04-10 | composição farmacêutica e uso de um profármaco de anfetamina |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1865980A4 (enExample) |
| JP (1) | JP2008535860A (enExample) |
| BR (1) | BRPI0612440A2 (enExample) |
| CA (1) | CA2603873A1 (enExample) |
| MX (1) | MX2007012507A (enExample) |
| WO (1) | WO2006121552A2 (enExample) |
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| US8318813B2 (en) | 2007-09-13 | 2012-11-27 | Lcs Group, Llc | Method of treating binge eating disorder |
| WO2010042120A1 (en) | 2008-10-09 | 2010-04-15 | Archimica, Inc. | Process for the synthesis of amphetamine derivatives |
| GB201002612D0 (en) * | 2010-02-16 | 2010-03-31 | Jagotec Ag | Improvements in or relating to organic compounds |
| US20140073589A1 (en) * | 2012-06-27 | 2014-03-13 | Shire Ag | Amphetamine Prodrugs |
| US11879019B2 (en) | 2016-12-19 | 2024-01-23 | The Regents Of The University Of California | Dual-enzyme responsive peptides |
| WO2018118903A1 (en) | 2016-12-19 | 2018-06-28 | The Regents Of The University Of California | Noncrushable pill formulatiions |
| ES2806995T3 (es) | 2017-09-20 | 2021-02-19 | Sandoz Ag | Sales cristalinas de un profármaco de dextroanfetamina |
| US12459965B2 (en) | 2017-10-09 | 2025-11-04 | Compass Pathfinder Limited | Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use |
| GB2571696B (en) | 2017-10-09 | 2020-05-27 | Compass Pathways Ltd | Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced |
| JP2022529353A (ja) | 2019-04-17 | 2022-06-21 | コンパス パスファインダー リミテッド | 神経認知障害、慢性疼痛を治療し、炎症を低減させる方法 |
| HUE059869T2 (hu) * | 2019-12-30 | 2023-01-28 | Labomed Pharmaceutical Company S A | Lizdexamfetamin-sókat tartalmazó orális oldatok |
| JP2023549405A (ja) | 2020-11-18 | 2023-11-24 | マインド メディシン, インコーポレイテッド | 心理療法を補助するためのmdmaプロドラッグ |
| US20250064759A1 (en) | 2021-12-16 | 2025-02-27 | Labomed Pharmaceutical Company S.A. | Container comprising a lisdexamfetamine containing oral solution |
| EP4561528A1 (en) | 2022-07-29 | 2025-06-04 | Labomed Pharmaceutical Company S.A. | Lisdexamfetamine containing oral solution |
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| US3878187A (en) * | 1972-09-11 | 1975-04-15 | Syva Co | Polypeptide derivatives of amphetamine and analogs for immunoassays |
| US6384020B1 (en) * | 1999-07-14 | 2002-05-07 | Shire Laboratories, Inc. | Rapid immediate release oral dosage form |
| IL158959A (en) * | 2001-05-25 | 2010-06-30 | Cephalon Inc | Solid pharmaceutical formulations comprising modafinil |
| US7105486B2 (en) * | 2002-02-22 | 2006-09-12 | New River Pharmaceuticals Inc. | Abuse-resistant amphetamine compounds |
| AU2004277400B2 (en) * | 2003-09-30 | 2009-01-22 | Shire Llc | Pharmaceutical compositions for prevention of overdose or abuse |
-
2006
- 2006-04-10 WO PCT/US2006/013221 patent/WO2006121552A2/en not_active Ceased
- 2006-04-10 EP EP06769808A patent/EP1865980A4/en not_active Withdrawn
- 2006-04-10 JP JP2008505617A patent/JP2008535860A/ja active Pending
- 2006-04-10 MX MX2007012507A patent/MX2007012507A/es unknown
- 2006-04-10 BR BRPI0612440-2A patent/BRPI0612440A2/pt not_active Application Discontinuation
- 2006-04-10 CA CA002603873A patent/CA2603873A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CA2603873A1 (en) | 2006-11-16 |
| WO2006121552A3 (en) | 2007-07-05 |
| WO2006121552A2 (en) | 2006-11-16 |
| WO2006121552A9 (en) | 2007-03-08 |
| JP2008535860A (ja) | 2008-09-04 |
| EP1865980A2 (en) | 2007-12-19 |
| MX2007012507A (es) | 2008-03-11 |
| EP1865980A4 (en) | 2009-11-11 |
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