BRPI0611620A2 - mimÉticos de glicocorticàide, mÉtodos de fazÊ-los, composiÇÕes farmacÊuticas e usos dos mesmos - Google Patents

mimÉticos de glicocorticàide, mÉtodos de fazÊ-los, composiÇÕes farmacÊuticas e usos dos mesmos

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Publication number
BRPI0611620A2
BRPI0611620A2 BRPI0611620-5A BRPI0611620A BRPI0611620A2 BR PI0611620 A2 BRPI0611620 A2 BR PI0611620A2 BR PI0611620 A BRPI0611620 A BR PI0611620A BR PI0611620 A2 BRPI0611620 A2 BR PI0611620A2
Authority
BR
Brazil
Prior art keywords
methods
pharmaceutical compositions
making
mimetics
compounds
Prior art date
Application number
BRPI0611620-5A
Other languages
English (en)
Inventor
Ingo Andreas Mugge
Michael Jason Burke
Mark Stephen Ralph
David S Thomson
Abdelhakim Hammach
Jennifer A Kowalski
Joerg Martin Bentzien
Original Assignee
Boehringer Ingelheim Int
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Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of BRPI0611620A2 publication Critical patent/BRPI0611620A2/pt

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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Neurosurgery (AREA)
  • Vascular Medicine (AREA)
  • Otolaryngology (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Child & Adolescent Psychology (AREA)
  • Transplantation (AREA)
  • Emergency Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)

Abstract

MIMÉTICOS DE GLICOCORTICàIDE, MÉTODOS DE FAZÊ-LOS, COMPOSIÇÕES FARMACÊUTICAS E USOS DOS MESMOS. Compostos da Fórmula (IA) e (IB) em que R¹, R², Rü, A, B, C, D, e E são como definidos aqui, ou um tautômero, prá-fármaco, solvato, ou saí do mesmo; composições farmacêuticas con-tendo tais compostos, e métodos de modular a função do receptor de glicocorticóide e métodos de tratar estados de doença ou condições mediadas pela função do receptor de glicocorticóide ou caracterizadas por processos inflamatórios, alérgicos, ou proliferativos em um paciente usando estes com- postos.
BRPI0611620-5A 2005-06-10 2006-06-08 mimÉticos de glicocorticàide, mÉtodos de fazÊ-los, composiÇÕes farmacÊuticas e usos dos mesmos BRPI0611620A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US68941205P 2005-06-10 2005-06-10
PCT/US2006/022651 WO2006135826A1 (en) 2005-06-10 2006-06-08 Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof

Publications (1)

Publication Number Publication Date
BRPI0611620A2 true BRPI0611620A2 (pt) 2009-01-13

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ID=37057165

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BRPI0611620-5A BRPI0611620A2 (pt) 2005-06-10 2006-06-08 mimÉticos de glicocorticàide, mÉtodos de fazÊ-los, composiÇÕes farmacÊuticas e usos dos mesmos

Country Status (17)

Country Link
US (1) US7622594B2 (pt)
EP (1) EP1893588A1 (pt)
JP (1) JP2008543780A (pt)
KR (1) KR20080027828A (pt)
CN (1) CN101193869B (pt)
AR (1) AR058006A1 (pt)
AU (1) AU2006257861A1 (pt)
BR (1) BRPI0611620A2 (pt)
CA (1) CA2610588A1 (pt)
IL (1) IL187976A0 (pt)
MX (1) MX2007014811A (pt)
NZ (1) NZ564696A (pt)
PE (1) PE20070112A1 (pt)
RU (1) RU2007148225A (pt)
TW (1) TW200716573A (pt)
WO (1) WO2006135826A1 (pt)
ZA (1) ZA200709430B (pt)

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ES2298508T3 (es) 2002-03-26 2008-05-16 Boehringer Ingelheim Pharmaceuticals Inc. Mimeticos de glucocorticoides, metodos para prepararlos, composiciones farmaceuticas y sus usos.
KR20050036982A (ko) * 2002-08-29 2005-04-20 베링거 인겔하임 파마슈티칼즈, 인코포레이티드 염증, 알러지 및 증식성 질환의 치료에 글루코코르티코이드모사체로 사용하기 위한 3-(설폰아미도에틸)-인돌 유도체
UY28526A1 (es) * 2003-09-24 2005-04-29 Boehringer Ingelheim Pharma Miméticos de glucocorticoides, métodos de preparación composiciones farmacéuticas y usos de los mismos
US7795272B2 (en) 2004-03-13 2010-09-14 Boehringer Ingelheim Pharmaceutical, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions and uses thereof
US7741361B2 (en) 2004-12-27 2010-06-22 Boehringer Ingelheim Pharmaceuticals, Inc. Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
EP2061767B1 (de) 2006-08-08 2014-12-17 Sanofi Arylaminoaryl-alkyl-substituierte Imidazolidin-2,4-dione, Verfahren zu ihrer Herstellung, diese Verbindungen enthaltende Arzneimittel und ihre Verwendung
JP2010508358A (ja) * 2006-11-01 2010-03-18 ブリストル−マイヤーズ スクイブ カンパニー グルココルチコイド受容体、ＡＰ−１、および／またはＮＦ−κＢ活性の調節剤、並びにその使用
TW200829578A (en) 2006-11-23 2008-07-16 Astrazeneca Ab Chemical compounds 537
AU2007329548A1 (en) * 2006-12-06 2008-06-12 Boehringer Ingelheim International Gmbh Glucocorticoid mimetics, methods of making them, pharmaceutical compositions, and uses thereof
JO2754B1 (en) * 2006-12-21 2014-03-15 استرازينكا ايه بي Amylendazoleil derivatives for the treatment of glucocorticoid-mediated disorders
WO2008079073A1 (en) * 2006-12-22 2008-07-03 Astrazeneca Ab Indazolyl sulphonamide derivatives for the treatment of glucocorticoid receptor mediated disorders
MX2009008439A (es) * 2007-02-12 2009-08-13 Intermune Inc Nuevos inhibidores de la replicacion del virus de hepatitis c.
US8143280B2 (en) 2007-09-27 2012-03-27 Hoffmann-La Roche Inc. Glucocorticoid receptor antagonists
WO2009069736A1 (ja) * 2007-11-28 2009-06-04 Kyowa Hakko Kirin Co., Ltd. 含窒素化合物
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