BRPI0520451A2 - métodos para tratamento de distúrbios associados a substáncias quìmicas - Google Patents
métodos para tratamento de distúrbios associados a substáncias quìmicasInfo
- Publication number
- BRPI0520451A2 BRPI0520451A2 BRPI0520451-8A BRPI0520451A BRPI0520451A2 BR PI0520451 A2 BRPI0520451 A2 BR PI0520451A2 BR PI0520451 A BRPI0520451 A BR PI0520451A BR PI0520451 A2 BRPI0520451 A2 BR PI0520451A2
- Authority
- BR
- Brazil
- Prior art keywords
- sub
- phenyl
- alkyl
- group
- methods
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/325—Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Anesthesiology (AREA)
- Gynecology & Obstetrics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Cephalosporin Compounds (AREA)
Abstract
MéTODOS PARA TRATAMENTO DE DISTúRBIOS ASSOCIADOS A SUBSTáNCIAS QUìMICAS. A presente invenção refere-se a um método para prevenir, tratar ou melhorar distúrbios associados a substâncias químicas, em um indivíduo com necessidade do mesmo compreendendo administrar ao indivíduo uma quantidade eficaz de um composto selecionado de: Fórmula (I), ou Fórmula (II) ou formas farmaceuticamente aceitáveis do mesmo, onde fenila é substituida em X com um a cinco átomos de halogênio selecionados do grupo que consiste em flúor, cloro, bromo e iodo; e, R~ 1~, R~ 2~, R~ 3~, R~ 4~, R~ 5~ e R~ 6~ são independentemente selecionados do grupo que consiste em hidrogênio e 01-04 alquila; onde C~ 1~-C~ 4~ alquila é opcionalmente substituído com fenila (e, onde fenila é opcionalmente substituida com substituintes independentemente selecionados do grupo que consiste em halogênio, C~ 1~-C~ 4~ alquila, C~ 1~-C~ 4~ alcáxi, amino, nitro e ciano). Além disso, estão incluídos métodos que envolvem a co-administração de compostos da invenção com um ou mais compostos conhecidos para o tratamento de distúrbios induzidos por substâncias químicas.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US2005/026439 WO2007018496A1 (en) | 2005-07-26 | 2005-07-26 | Methods for treating substance-related disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0520451A2 true BRPI0520451A2 (pt) | 2009-05-12 |
Family
ID=35064669
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0520451-8A BRPI0520451A2 (pt) | 2005-07-26 | 2005-07-26 | métodos para tratamento de distúrbios associados a substáncias quìmicas |
Country Status (13)
Country | Link |
---|---|
EP (1) | EP1928451B1 (pt) |
JP (1) | JP5094720B2 (pt) |
KR (1) | KR101199499B1 (pt) |
CN (1) | CN101272776B (pt) |
AT (1) | ATE538784T1 (pt) |
AU (1) | AU2005335241B9 (pt) |
BR (1) | BRPI0520451A2 (pt) |
CA (1) | CA2616721C (pt) |
EA (1) | EA019935B1 (pt) |
ES (1) | ES2385087T3 (pt) |
IL (1) | IL189003A0 (pt) |
NO (1) | NO20080877L (pt) |
WO (1) | WO2007018496A1 (pt) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006133393A1 (en) | 2005-06-08 | 2006-12-14 | Sk Holdings Co., Ltd. | Treatment of sleep-wake disorders |
JP6095366B2 (ja) | 2009-06-22 | 2017-03-15 | エスケー バイオファーマシューティカルズ カンパニー リミテッド | 疲労を治療又は予防するための方法 |
US8232315B2 (en) * | 2009-06-26 | 2012-07-31 | Sk Biopharmaceuticals Co., Ltd. | Methods for treating drug addiction and improving addiction-related behavior |
EP2496228B1 (en) | 2009-11-06 | 2014-01-15 | SK Biopharmaceuticals Co., Ltd. | Methods for treating attention-deficit/hyperactivity disorder |
US8927602B2 (en) | 2009-11-06 | 2015-01-06 | Sk Biopharmaceuticals Co., Ltd. | Methods for treating fibromyalgia syndrome |
US9610274B2 (en) | 2010-06-30 | 2017-04-04 | Sk Biopharmaceuticals Co., Ltd. | Methods for treating bipolar disorder |
US8609849B1 (en) | 2010-11-30 | 2013-12-17 | Fox Chase Chemical Diversity Center, Inc. | Hydroxylated sulfamides exhibiting neuroprotective action and their method of use |
SI2968208T1 (sl) | 2013-03-13 | 2023-02-28 | Jazz Pharmaceuticals Ireland Limited, | Zdravljenje katapleksije |
CN110638804A (zh) | 2013-07-18 | 2020-01-03 | 爵士制药国际Iii有限公司 | 治疗肥胖 |
US10195151B2 (en) | 2016-09-06 | 2019-02-05 | Jazz Pharmaceuticals International Iii Limited | Formulations of (R)-2-amino-3-phenylpropyl carbamate |
CA3065522A1 (en) | 2017-06-02 | 2018-12-06 | Jazz Pharmaceuticals Ireland Limited | Methods and compositions for treating excessive sleepiness |
JP7257091B2 (ja) * | 2019-06-27 | 2023-04-13 | 沼澤 敏彦 | 認知症の治療及び予防薬 |
US10940133B1 (en) | 2020-03-19 | 2021-03-09 | Jazz Pharmaceuticals Ireland Limited | Methods of providing solriamfetol therapy to subjects with impaired renal function |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3313692A (en) * | 1958-04-21 | 1967-04-11 | Armour Pharma | Method of inducing calming and muscle relaxation with carbamates |
DE60220043T2 (de) * | 2001-02-27 | 2008-01-10 | Ortho-Mcneil Pharmaceutical, Inc. | Carbamatverbindungen zur vorbeugung oder behandlung von neurodegenerativen störungen |
ES2291454T3 (es) * | 2001-02-27 | 2008-03-01 | Ortho-Mcneil Pharmaceutical, Inc. | Utilizacion de carbamatos para prevenir o tratar trastornos del movimiento. |
ES2295320T3 (es) * | 2001-02-27 | 2008-04-16 | Ortho-Mcneil Pharmaceutical, Inc. | Compuestos de carbamato utiles para prevenir o tratar el trastorno bipolar. |
WO2002067927A1 (en) * | 2001-02-27 | 2002-09-06 | Ortho-Mcneil Pharmaceutical, Inc. | Carbamate compounds for use in preventing or treating psychotic disorders |
US20070021500A1 (en) * | 2005-07-12 | 2007-01-25 | Twyman Roy E | Methods for neuroprotection |
-
2005
- 2005-07-26 AU AU2005335241A patent/AU2005335241B9/en active Active
- 2005-07-26 ES ES05775692T patent/ES2385087T3/es active Active
- 2005-07-26 CN CN200580051664XA patent/CN101272776B/zh active Active
- 2005-07-26 BR BRPI0520451-8A patent/BRPI0520451A2/pt not_active Application Discontinuation
- 2005-07-26 JP JP2008523847A patent/JP5094720B2/ja active Active
- 2005-07-26 EP EP05775692A patent/EP1928451B1/en active Active
- 2005-07-26 AT AT05775692T patent/ATE538784T1/de active
- 2005-07-26 CA CA2616721A patent/CA2616721C/en active Active
- 2005-07-26 WO PCT/US2005/026439 patent/WO2007018496A1/en active Application Filing
- 2005-07-26 EA EA200800422A patent/EA019935B1/ru not_active IP Right Cessation
- 2005-07-26 KR KR1020087004533A patent/KR101199499B1/ko active IP Right Grant
-
2008
- 2008-01-24 IL IL189003A patent/IL189003A0/en unknown
- 2008-02-19 NO NO20080877A patent/NO20080877L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
KR101199499B1 (ko) | 2012-11-09 |
IL189003A0 (en) | 2008-11-03 |
JP5094720B2 (ja) | 2012-12-12 |
EA200800422A1 (ru) | 2008-10-30 |
CN101272776B (zh) | 2012-10-03 |
AU2005335241B2 (en) | 2012-11-15 |
ATE538784T1 (de) | 2012-01-15 |
AU2005335241A1 (en) | 2007-02-15 |
WO2007018496A1 (en) | 2007-02-15 |
CA2616721C (en) | 2014-01-21 |
JP2009502914A (ja) | 2009-01-29 |
NO20080877L (no) | 2008-02-19 |
CA2616721A1 (en) | 2007-02-15 |
KR20080037055A (ko) | 2008-04-29 |
EA019935B1 (ru) | 2014-07-30 |
CN101272776A (zh) | 2008-09-24 |
ES2385087T3 (es) | 2012-07-18 |
AU2005335241B9 (en) | 2012-12-20 |
EP1928451B1 (en) | 2011-12-28 |
EP1928451A1 (en) | 2008-06-11 |
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Owner name: JOHNSON AND JOHNSON (US) Free format text: TRANSFERIDO DE: JANSSEN PHARMACEUTICA N.V. |
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B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
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B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] |
Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS. |
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B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL |