BRPI0520012A2 - identificação de marcadores moleculares de diagnóstico para endometriose em linfócitos do sangue - Google Patents

identificação de marcadores moleculares de diagnóstico para endometriose em linfócitos do sangue

Info

Publication number
BRPI0520012A2
BRPI0520012A2 BRPI0520012-1A BRPI0520012A BRPI0520012A2 BR PI0520012 A2 BRPI0520012 A2 BR PI0520012A2 BR PI0520012 A BRPI0520012 A BR PI0520012A BR PI0520012 A2 BRPI0520012 A2 BR PI0520012A2
Authority
BR
Brazil
Prior art keywords
endometriosis
identification
value
blood lymphocyte
molecular markers
Prior art date
Application number
BRPI0520012-1A
Other languages
English (en)
Inventor
Idhaliz Flores
Spyro Mousses
Ester Rozenblum
Original Assignee
Us Gov Health & Human Serv
Ponce School Of Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Gov Health & Human Serv, Ponce School Of Medicine filed Critical Us Gov Health & Human Serv
Publication of BRPI0520012A2 publication Critical patent/BRPI0520012A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Reproductive Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

IDENTIFICAçãO DE MARCADORES MOLECULARES DE DIAGNóSTICO PARA ENDOMETRIOSE EM LINFóCITOS DO SANGUE. A invenção compreende um método para identificar e prever a pré-disposição à endometriose em sujeitos fêmeas compreendendo a determinação do nível de expressão gêníca de pelo menos um gene ou proteína ou peptídeo diferencialmente expresso de leucócitos do sangue periférico em uma amostra de leucócitos de sangue periférico ou sangue periférico em um sujeito para fornecer um primeiro valor, determinando o nível da expressão gênica de pelo menos um gene ou proteína ou peptideo diferencialmente expresso dos citados leucócitos em um controle ou referência padrão para fornecer um segundo valor, e compara se existe uma diferença entre o primeiro e o segundo valor.
BRPI0520012-1A 2005-02-18 2005-12-09 identificação de marcadores moleculares de diagnóstico para endometriose em linfócitos do sangue BRPI0520012A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65433105P 2005-02-18 2005-02-18
PCT/US2005/044723 WO2006091254A1 (en) 2005-02-18 2005-12-09 Identification of molecular diagnostic markers for endometriosis in blood lymphocytes

Publications (1)

Publication Number Publication Date
BRPI0520012A2 true BRPI0520012A2 (pt) 2009-04-14

Family

ID=36182367

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0520012-1A BRPI0520012A2 (pt) 2005-02-18 2005-12-09 identificação de marcadores moleculares de diagnóstico para endometriose em linfócitos do sangue

Country Status (13)

Country Link
US (1) US20090208939A1 (pt)
EP (1) EP1848818A1 (pt)
JP (1) JP2008537474A (pt)
KR (1) KR20080016789A (pt)
CN (1) CN101124340A (pt)
AU (1) AU2005327929A1 (pt)
BR (1) BRPI0520012A2 (pt)
CA (1) CA2596932A1 (pt)
IL (1) IL184920A0 (pt)
MX (1) MX2007009562A (pt)
NO (1) NO20074762L (pt)
WO (1) WO2006091254A1 (pt)
ZA (1) ZA200707752B (pt)

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US9222938B2 (en) * 2001-12-04 2015-12-29 Michael Tainsky Neoepitope detection of disease using protein arrays
EP2118321A4 (en) * 2007-02-06 2010-06-30 Genizon Biosciences GENCARTS OF HUMAN GENES ASSOCIATED WITH ENDOMETRIOSIS
US8932993B1 (en) 2007-06-11 2015-01-13 Juneau Biosciences, LLC. Method of testing for endometriosis and treatment therefor
US11287425B2 (en) 2009-04-22 2022-03-29 Juneau Biosciences, Llc Genetic markers associated with endometriosis and use thereof
WO2009140126A1 (en) * 2008-05-14 2009-11-19 Juneau Biosciences, Llc Method of administering a therapeutic
JP5503942B2 (ja) 2009-10-30 2014-05-28 シスメックス株式会社 疾患の罹患の判定方法
EP2348129A1 (en) * 2010-01-21 2011-07-27 Sanofi Methods and uses relating to the identification of compound involved in pain as well as methods of diagnosing algesia
KR101333207B1 (ko) * 2011-07-13 2013-11-26 부산대학교 산학협력단 자궁내막증과 연관된 유전자 마커 및 이의 용도
WO2013067451A2 (en) 2011-11-04 2013-05-10 Population Diagnostics Inc. Methods and compositions for diagnosing, prognosing, and treating neurological conditions
EP2812452B1 (en) 2012-02-09 2020-05-27 Population Bio, Inc. Methods and compositions for screening and treating developmental disorders
KR101445560B1 (ko) * 2012-05-10 2014-09-29 한국수력원자력 주식회사 저준위 전리방사선에 민감한 유전자 검출 방법 및 상기 방법으로 검출된 유전자
US9976180B2 (en) 2012-09-14 2018-05-22 Population Bio, Inc. Methods for detecting a genetic variation in subjects with parkinsonism
US9434991B2 (en) 2013-03-07 2016-09-06 Juneau Biosciences, LLC. Method of testing for endometriosis and treatment therefor
CN110129425A (zh) * 2013-06-28 2019-08-16 睿智研究实验室私人有限公司 脓毒症生物标志物及其应用
DK2891722T3 (en) 2013-11-12 2019-01-07 Population Bio Inc METHODS AND COMPOSITIONS FOR DIAGNOSTICING, PROGRAMMING AND TREATMENT OF ENDOMETRIOSIS
DE102014203235A1 (de) * 2014-02-24 2015-08-27 Mahle International Gmbh Klimagerät, insbesondere für ein Kraftfahrzeug und Verfahren zur Herstellung einer Komponente eines Klimagerätes
RU2558854C1 (ru) * 2014-06-23 2015-08-10 Федеральное государственное автономное образовательное учреждение высшего профессионального образования "Белгородский государственный национальный исследовательский университет" Способ прогнозирования риска развития эндометриоза
JP2016077234A (ja) * 2014-10-17 2016-05-16 国立大学法人鳥取大学 子宮内膜症の早期診断のための診断キット、診断マーカー及び検出方法
CN107326065B (zh) * 2016-04-29 2022-07-29 博尔诚（北京）科技有限公司 一种基因标识物的筛选方法及其应用
CN107858415B (zh) * 2016-09-19 2021-05-28 深圳华大生命科学研究院 用于子宫腺肌症检测的生物标志物组合及其应用
US10240205B2 (en) 2017-02-03 2019-03-26 Population Bio, Inc. Methods for assessing risk of developing a viral disease using a genetic test
WO2019169113A1 (en) * 2018-03-02 2019-09-06 Ponce Medical School Foundation, Inc. Compositions and methods for the treatment of endometriosis
CN108456723A (zh) * 2018-03-21 2018-08-28 福州福瑞医学检验实验室有限公司 一种子宫内膜异位症风险预测的基因检测引物和试剂盒
JP2021521803A (ja) * 2018-04-20 2021-08-30 ザ ボード オブ リージェンツ オブ ザ ユニバーシティー オブ テキサス システム 子宮内膜症の治療のための組成物および方法
US11906529B1 (en) * 2018-04-27 2024-02-20 Marshall University Research Corporation Methods for treatment and diagnosis of endometriosis
EP4177356A1 (en) 2018-08-08 2023-05-10 PML Screening, LLC Methods for assessing risk of developing a viral disease using a genetic test

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2497132A1 (en) * 2002-08-30 2004-03-25 Oncotherapy Science, Inc. Method of diagnosing ovarian endometriosis

Also Published As

Publication number Publication date
AU2005327929A1 (en) 2006-08-31
WO2006091254A1 (en) 2006-08-31
KR20080016789A (ko) 2008-02-22
IL184920A0 (en) 2007-12-03
CA2596932A1 (en) 2006-08-31
JP2008537474A (ja) 2008-09-18
NO20074762L (no) 2007-11-16
CN101124340A (zh) 2008-02-13
ZA200707752B (en) 2010-05-26
US20090208939A1 (en) 2009-08-20
MX2007009562A (es) 2008-03-11
EP1848818A1 (en) 2007-10-31

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B11E Dismissal acc. art. 34 of ipl - requirements for examination incomplete
B11T Dismissal of application maintained [chapter 11.20 patent gazette]