BRPI0517940A - formas de dosagem sólida oral contendo uma baixa dose de estradiol bem como processo para fabricação e uso da mesma - Google Patents
formas de dosagem sólida oral contendo uma baixa dose de estradiol bem como processo para fabricação e uso da mesmaInfo
- Publication number
- BRPI0517940A BRPI0517940A BRPI0517940-8A BRPI0517940A BRPI0517940A BR PI0517940 A BRPI0517940 A BR PI0517940A BR PI0517940 A BRPI0517940 A BR PI0517940A BR PI0517940 A BRPI0517940 A BR PI0517940A
- Authority
- BR
- Brazil
- Prior art keywords
- estradiol
- dosage forms
- low dose
- oral solid
- solid dosage
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Endocrinology (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Reproductive Health (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
Abstract
FORMAS DE DOSAGEM SóLIDA ORAL CONTEDO UMA BAIXA DOSE DE ESTRADIOL BEM COMO PROCESSO PARA FABRICAçãO E USO DA MESMA. A presente invenção refere-se a formas de dosagem sólida oral contendo uma dose muito baixa de estradiol. As formas de dosagem são formuladas em uma maneira de modo a evitar degradação do estradiol e minimizar o teor de polivinil pirrolidona enquanto ainda obtendo similar rápida dissolução do estradiol. As formas de dosagem são úteis em prevenção ou tratamento de uma condição física em uma mulher causada por insuficientes níveis endógenos de estradiol.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04078014 | 2004-11-02 | ||
| PCT/EP2005/011726 WO2006048261A2 (en) | 2004-11-02 | 2005-11-01 | Oral solid dosage forms containing a low dose of estradiol |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0517940A true BRPI0517940A (pt) | 2008-10-21 |
Family
ID=34928627
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0517940-8A BRPI0517940A (pt) | 2004-11-02 | 2005-11-01 | formas de dosagem sólida oral contendo uma baixa dose de estradiol bem como processo para fabricação e uso da mesma |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP1814526A2 (pt) |
| JP (1) | JP2008518895A (pt) |
| KR (1) | KR20070085558A (pt) |
| CN (1) | CN101094656A (pt) |
| AR (1) | AR053650A1 (pt) |
| AU (1) | AU2005300658A1 (pt) |
| BR (1) | BRPI0517940A (pt) |
| CA (1) | CA2585095A1 (pt) |
| CR (1) | CR9112A (pt) |
| CU (1) | CU20070094A7 (pt) |
| EA (1) | EA013262B1 (pt) |
| GT (1) | GT200500315A (pt) |
| IL (1) | IL182635A0 (pt) |
| MX (1) | MX2007005281A (pt) |
| NO (1) | NO20072704L (pt) |
| PA (1) | PA8651401A1 (pt) |
| PE (1) | PE20061126A1 (pt) |
| TW (1) | TW200621312A (pt) |
| UY (1) | UY29185A1 (pt) |
| WO (1) | WO2006048261A2 (pt) |
| ZA (1) | ZA200705012B (pt) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8022053B2 (en) | 2004-11-02 | 2011-09-20 | Bayer Schering Pharma Aktiengesellschaft | Oral solid dosage forms containing a low dose of estradiol |
| KR20080047959A (ko) * | 2006-11-27 | 2008-05-30 | 주식회사 엠디바이오알파 | 비만, 당뇨, 대사성 질환, 퇴행성 질환 및 미토콘드리아이상 질환의 치료 또는 예방을 위한 나프토퀴논계 약제조성물 |
| DE102009007771B4 (de) | 2009-02-05 | 2012-02-16 | Bayer Schering Pharma Aktiengesellschaft | Bukkales Applikationssystem, 17α-Estradiol enthaltend |
| BR112012026115B1 (pt) | 2010-04-15 | 2019-12-24 | Bayer Ip Gmbh | forma de dosagem oral sólida, seu uso, e unidade de acondicionamento |
| US20130140210A1 (en) | 2010-04-15 | 2013-06-06 | Bayer Intellectual Property Gmbh | Low-dosed solid oral dosage forms for hrt |
| CN112516149B (zh) * | 2020-07-21 | 2023-07-18 | 南方医科大学 | 苯甲酸雌二醇或其药物可接受盐在制备抗冠状病毒的药物中的应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL125071C (pt) * | 1963-12-24 | |||
| US4755386A (en) * | 1986-01-22 | 1988-07-05 | Schering Corporation | Buccal formulation |
| US5073374A (en) * | 1988-11-30 | 1991-12-17 | Schering Corporation | Fast dissolving buccal tablet |
| FR2739558B1 (fr) * | 1995-10-05 | 1997-11-28 | Innothera Lab Sa | Forme galenique unitaire pour hormonotherapie locale de la secheresse vaginale |
| FR2754179B1 (fr) * | 1996-10-08 | 1998-12-24 | Theramex | Nouvelle composition hormononale et son utilisation |
| US6326366B1 (en) * | 2000-08-22 | 2001-12-04 | Protein Technologies International | Hormone replacement therapy |
| AU2001295359A1 (en) * | 2000-10-30 | 2002-05-15 | University Of Zurich | GnRH analogues for treatment of urinary incontinence |
| ATE532521T1 (de) * | 2000-12-15 | 2011-11-15 | Novo Nordisk Femcare Ag | Verwendung eines östrogens bei der herstellung einer östrogenhaltigen zusammensetzung zur behandlung von atrophischer vaginitis |
| FR2823976A1 (fr) * | 2001-04-25 | 2002-10-31 | Theramex | Nouvelle composition hormonale et son utilisation |
| US20030018018A1 (en) * | 2001-07-10 | 2003-01-23 | Medical College Of Hampton Roads | Ultra low dose oral contraceptives with sustained efficacy and induced amenorrhea |
| US6962908B2 (en) * | 2001-12-21 | 2005-11-08 | Warner Chilcott Company Inc. | Oral pharmaceutical products containing 17 β-estradiol-3-lower alkanoate, method of administering the same and process of preparation |
| JP2004155779A (ja) * | 2002-10-16 | 2004-06-03 | Taisho Pharmaceut Co Ltd | 更年期症の予防・治療用経口組成物 |
-
2005
- 2005-10-31 GT GT200500315A patent/GT200500315A/es unknown
- 2005-10-31 UY UY29185A patent/UY29185A1/es not_active Application Discontinuation
- 2005-11-01 EA EA200700979A patent/EA013262B1/ru not_active IP Right Cessation
- 2005-11-01 KR KR1020077012174A patent/KR20070085558A/ko not_active Application Discontinuation
- 2005-11-01 CN CNA200580045694XA patent/CN101094656A/zh active Pending
- 2005-11-01 WO PCT/EP2005/011726 patent/WO2006048261A2/en active Application Filing
- 2005-11-01 JP JP2007538360A patent/JP2008518895A/ja active Pending
- 2005-11-01 BR BRPI0517940-8A patent/BRPI0517940A/pt not_active IP Right Cessation
- 2005-11-01 AU AU2005300658A patent/AU2005300658A1/en not_active Abandoned
- 2005-11-01 MX MX2007005281A patent/MX2007005281A/es not_active Application Discontinuation
- 2005-11-01 EP EP05800512A patent/EP1814526A2/en not_active Withdrawn
- 2005-11-01 TW TW094138264A patent/TW200621312A/zh unknown
- 2005-11-01 CA CA002585095A patent/CA2585095A1/en not_active Abandoned
- 2005-11-02 PE PE2005001279A patent/PE20061126A1/es not_active Application Discontinuation
- 2005-11-02 PA PA20058651401A patent/PA8651401A1/es unknown
- 2005-11-02 AR ARP050104580A patent/AR053650A1/es unknown
-
2007
- 2007-04-18 IL IL182635A patent/IL182635A0/en unknown
- 2007-04-30 CU CU20070094A patent/CU20070094A7/es unknown
- 2007-05-09 CR CR9112A patent/CR9112A/es not_active Application Discontinuation
- 2007-05-29 NO NO20072704A patent/NO20072704L/no not_active Application Discontinuation
- 2007-06-01 ZA ZA200705012A patent/ZA200705012B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO20072704L (no) | 2007-05-29 |
| PA8651401A1 (es) | 2006-12-07 |
| MX2007005281A (es) | 2008-03-11 |
| WO2006048261A2 (en) | 2006-05-11 |
| CR9112A (es) | 2007-11-23 |
| EA013262B1 (ru) | 2010-04-30 |
| AU2005300658A1 (en) | 2006-05-11 |
| UY29185A1 (es) | 2006-05-31 |
| CN101094656A (zh) | 2007-12-26 |
| EA200700979A1 (ru) | 2007-10-26 |
| ZA200705012B (en) | 2008-10-29 |
| AR053650A1 (es) | 2007-05-16 |
| JP2008518895A (ja) | 2008-06-05 |
| TW200621312A (en) | 2006-07-01 |
| CA2585095A1 (en) | 2006-05-11 |
| WO2006048261A3 (en) | 2006-09-21 |
| IL182635A0 (en) | 2007-07-24 |
| GT200500315A (es) | 2006-06-06 |
| PE20061126A1 (es) | 2006-11-11 |
| KR20070085558A (ko) | 2007-08-27 |
| EP1814526A2 (en) | 2007-08-08 |
| CU20070094A7 (es) | 2009-09-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DOP2006000057A (es) | Composición farmaceútica para el tratamiento del cáncer | |
| BRPI0906181A2 (pt) | "método para tratamento de uma disfunção hiperproliferativa, composição farmacêutica, uso de uma combinação terapêutica na fabricação de um medicamento para o tratamento de câncer, artigo de fabricação para tratamento de uma disfunção hiperproliferativa, método para determinação de compostos a serem usados em combinação para o tratamento de câncer e método para determinação de uma combinação terapêutica a ser usada para o tratamento de câncer" | |
| BRPI0911273B8 (pt) | composição farmacêutica compreendendo um inibidor de dpp-iv, bem como processo para sua preparação | |
| BRPI0509927A (pt) | composição farmacêutica, uso de uma composição de matéria, e, uso de uma combinação terapeuticamente eficaz de um oligonucleotìdeo anti-sentido de survivina e cloridrato de gemcitabina | |
| BRPI0517940A (pt) | formas de dosagem sólida oral contendo uma baixa dose de estradiol bem como processo para fabricação e uso da mesma | |
| CO6361917A2 (es) | Tratamiento de la diabetes en pacientes con control glucemico insuficiente a pesar de la terapia con un farmaco oral o no oral antidiabetico | |
| CL2008001855A1 (es) | Compuestos ciclicos condensados derivados del boro; composicion farmaceutica; y uso en el tratamiento y/o prevencion de una enfermedad infecciosa. | |
| AR109263A2 (es) | Composición que comprende moxidectina | |
| NI200800169A (es) | Uso de derivados de sulfamidas heterocíclicas benzo-fusionadas para el tratamiento del dolor | |
| MX2010002278A (es) | Farmacos antivirales para el tratamiento de una infeccion por arenavirus. | |
| CR8574A (es) | Compuestos silinano como inhibidores de cisteina proteasa | |
| UY30158A1 (es) | Uso de derivados de benzo-heteroaril sulfamida para el tratamiento del dolor | |
| MX2009012920A (es) | Compuestos heptaciclicos y usos farmaceuticos de los mismos para la prevencion y tratamiento de diabetes y sindrome metabolico. | |
| PE20070333A1 (es) | Composicion farmaceutica que comprende agomelatina para el tratamiento de transtornos del sueno en pacientes deprimidos | |
| ATE353655T1 (de) | Myo-inositol hexaphosphat zur topischen verwendung | |
| BRPI0606528A8 (pt) | composição para uso no fabrico de medicamentos de tratamento da infertilidade masculina e uso da mesma | |
| BRPI0509667A (pt) | azaquinazolinas substituìdas com eficácia antiviral | |
| UY28115A1 (es) | Derivados del acido isoftalico | |
| BRPI0607976A2 (pt) | composição farmacêutica e uso de uma composição | |
| UY27733A1 (es) | Derivados de ciclopenteno. | |
| BRPI0702847A (pt) | formas de dosagem unitária de temozolomida | |
| CO6410284A2 (es) | Composición farmacéutica oral para uso en enfermedades respiratorias | |
| ATE471375T1 (de) | Vglut-spezifische dsrna-verbindungen | |
| CL2004000633A1 (es) | Compuestos copolimeros, composicion farmaceutica que los contiene y procedimiento de preparacion, utiles en el tratamiento de enfermedades metabolicas oseas. | |
| UA96339C2 (ru) | Гептациклические соединения и их фармацевтическое применение для профилактики и лечения диабета и метаболического синдрома |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 6A ANUIDADE. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2160 DE 29/05/2012. |