BRPI0514196A - composição, uso de composto, kit farmacêutico, e, método de contracepção de um mamìfero - Google Patents
composição, uso de composto, kit farmacêutico, e, método de contracepção de um mamìferoInfo
- Publication number
- BRPI0514196A BRPI0514196A BRPI0514196-6A BRPI0514196A BRPI0514196A BR PI0514196 A BRPI0514196 A BR PI0514196A BR PI0514196 A BRPI0514196 A BR PI0514196A BR PI0514196 A BRPI0514196 A BR PI0514196A
- Authority
- BR
- Brazil
- Prior art keywords
- contraception
- composition
- compost
- mammal
- pharmaceutical kit
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/18—Feminine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Diabetes (AREA)
- Pregnancy & Childbirth (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
COMPOSIçãO, USO DE COMPOSTO, KIT FARMACêUTICO, E, MéTODO DE CONTRACEPçãO DE UM MAMìFERO Derivados de pirrol-oxindol úteis como antagonistas de receptor de progesterona são proporcionados. Composições farmacêuticas contendo estes derivados são descritas, bem como o seu uso em contracepção e condições relacionadas com hormónio.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US59990004P | 2004-08-09 | 2004-08-09 | |
PCT/US2005/023782 WO2006023107A1 (en) | 2004-08-09 | 2005-07-06 | Progesterone receptor modulators comprising pyrrole-oxindole derivatives and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0514196A true BRPI0514196A (pt) | 2008-06-03 |
Family
ID=34993110
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0514196-6A BRPI0514196A (pt) | 2004-08-09 | 2005-07-06 | composição, uso de composto, kit farmacêutico, e, método de contracepção de um mamìfero |
Country Status (20)
Country | Link |
---|---|
US (1) | US20060030615A1 (pt) |
EP (1) | EP1778222A1 (pt) |
JP (1) | JP2008509216A (pt) |
KR (1) | KR20070039925A (pt) |
CN (1) | CN101001625A (pt) |
AR (1) | AR049708A1 (pt) |
AU (1) | AU2005277879A1 (pt) |
BR (1) | BRPI0514196A (pt) |
CA (1) | CA2573310A1 (pt) |
EC (1) | ECSP077236A (pt) |
GT (1) | GT200500183A (pt) |
IL (1) | IL180955A0 (pt) |
MX (1) | MX2007001614A (pt) |
NO (1) | NO20070723L (pt) |
PA (1) | PA8638701A1 (pt) |
PE (1) | PE20060555A1 (pt) |
RU (1) | RU2007101304A (pt) |
TW (1) | TW200605882A (pt) |
WO (1) | WO2006023107A1 (pt) |
ZA (1) | ZA200701156B (pt) |
Families Citing this family (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6407101B1 (en) * | 1999-05-04 | 2002-06-18 | American Home Products Corporation | Cyanopyrroles |
US6391907B1 (en) * | 1999-05-04 | 2002-05-21 | American Home Products Corporation | Indoline derivatives |
PA8638601A1 (es) | 2004-07-07 | 2006-07-03 | Wyeth Corp | Regimenes y kits de progestina ciclica |
GT200500185A (es) * | 2004-08-09 | 2006-04-10 | Moduladores del receptor de progesterona que comprenden derivados de pirrol-oxindol y sus usos | |
MY145694A (en) | 2005-04-11 | 2012-03-30 | Xenon Pharmaceuticals Inc | Spiroheterocyclic compounds and their uses as therapeutic agents |
MY144968A (en) | 2005-04-11 | 2011-11-30 | Xenon Pharmaceuticals Inc | Spiro-oxindole compounds and their uses as therapeutic agents |
CN101166521A (zh) | 2005-04-28 | 2008-04-23 | 惠氏公司 | 通过湿制粒法制备包含微粒化他那普戈特的组合物 |
WO2006116514A2 (en) * | 2005-04-28 | 2006-11-02 | Wyeth | Micronized tanaproget, compositions, and methods of preparing the same |
ES2340518T3 (es) * | 2005-04-28 | 2010-06-04 | Wyeth Llc | Tanaproget micronizado y composiciones que lo contienen. |
PE20070182A1 (es) * | 2005-07-29 | 2007-03-06 | Wyeth Corp | Derivados cianopirrol-fenil amida como moduladores del receptor de progesterona |
PE20070404A1 (es) | 2005-07-29 | 2007-05-10 | Wyeth Corp | Compuestos derivados de cianopirrol-sulfonamida como moduladores del receptor de progesterona |
PE20070220A1 (es) | 2005-07-29 | 2007-03-19 | Wyeth Corp | Proceso para la sintesis de moduladores del receptor de progesterona |
US7319152B2 (en) * | 2005-09-19 | 2008-01-15 | Wyeth | 5-Aryl-indan-1-one and analogs useful as progesterone receptor modulators |
US20070066628A1 (en) * | 2005-09-19 | 2007-03-22 | Wyeth | 5-Aryl-indan-1-ol and analogs useful as progesterone receptor modulators |
US7414142B2 (en) | 2005-09-19 | 2008-08-19 | Wyeth | 5-aryl-indan-1-one oximes and analogs useful as progesterone receptor modulators |
US20070093548A1 (en) * | 2005-10-25 | 2007-04-26 | Wyeth | Use of progesterone receptor modulators |
US20070213526A1 (en) * | 2006-03-07 | 2007-09-13 | Wyeth | Purification of progesterone receptor modulators |
WO2008021422A2 (en) * | 2006-08-17 | 2008-02-21 | Wyeth | Process for the preparation of indolin-2-one derivatives useful as pr modulators |
JP5460324B2 (ja) | 2006-10-12 | 2014-04-02 | ゼノン・ファーマシューティカルズ・インコーポレイテッド | 治療剤としてのスピロ−オキシインドール化合物の使用 |
TW200848019A (en) * | 2007-03-06 | 2008-12-16 | Wyeth Corp | Aryl sulfonamides useful for modulation of the progesterone receptor |
TW200848021A (en) * | 2007-03-06 | 2008-12-16 | Wyeth Corp | Sulfonylated heterocycles useful for modulation of the progesterone receptor |
US20080312306A1 (en) * | 2007-06-15 | 2008-12-18 | Wyeth | Polymorphs, solvates, and hydrate of 5-(4'-fluoro-2'-oxo-1',2'-dihydrospiro[cyclopropane-1,3'-indol]-5'-yl)-1-methyl-1h-pyrrole-2-carbonitrile |
US20080319204A1 (en) * | 2007-06-25 | 2008-12-25 | Wyeth | Process for the synthesis of progesterone receptor modulators |
BRPI0819571A2 (pt) * | 2007-12-20 | 2019-09-24 | Teva Womenss Health Inc | "método para contracepção de emergência, pacote farmacêutico para contracepção de emergência e composição farmacêutica" |
EP2350091B1 (en) | 2008-10-17 | 2015-06-03 | Xenon Pharmaceuticals Inc. | Spiro-oxindole compounds and their use as therapeutic agents |
DK2350090T3 (en) | 2008-10-17 | 2015-09-07 | Xenon Pharmaceuticals Inc | Spiro-oxindole compounds and their use as therapeutic agents |
AR077252A1 (es) | 2009-06-29 | 2011-08-10 | Xenon Pharmaceuticals Inc | Enantiomeros de compuestos de espirooxindol y sus usos como agentes terapeuticos |
WO2011047174A1 (en) | 2009-10-14 | 2011-04-21 | Xenon Pharmaceuticals Inc. | Synthetic methods for spiro-oxindole compounds |
WO2011069298A1 (en) * | 2009-12-11 | 2011-06-16 | F. Hoffmann-La Roche Ag | Novel cyclopropane indolinone derivatives |
US9504671B2 (en) | 2010-02-26 | 2016-11-29 | Xenon Pharmaceuticals Inc. | Pharmaceutical compositions of spiro-oxindole compound for topical administration and their use as therapeutic agents |
US9301920B2 (en) | 2012-06-18 | 2016-04-05 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
PT2782584T (pt) | 2011-11-23 | 2021-09-02 | Therapeuticsmd Inc | Preparações e terapias de substituição para hormonoterapias naturais combinadas |
US20150196640A1 (en) | 2012-06-18 | 2015-07-16 | Therapeuticsmd, Inc. | Progesterone formulations having a desirable pk profile |
US10806697B2 (en) | 2012-12-21 | 2020-10-20 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10806740B2 (en) | 2012-06-18 | 2020-10-20 | Therapeuticsmd, Inc. | Natural combination hormone replacement formulations and therapies |
US20130338122A1 (en) | 2012-06-18 | 2013-12-19 | Therapeuticsmd, Inc. | Transdermal hormone replacement therapies |
US10537581B2 (en) | 2012-12-21 | 2020-01-21 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10568891B2 (en) | 2012-12-21 | 2020-02-25 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US11266661B2 (en) | 2012-12-21 | 2022-03-08 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US10471072B2 (en) | 2012-12-21 | 2019-11-12 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US11246875B2 (en) | 2012-12-21 | 2022-02-15 | Therapeuticsmd, Inc. | Vaginal inserted estradiol pharmaceutical compositions and methods |
US9180091B2 (en) | 2012-12-21 | 2015-11-10 | Therapeuticsmd, Inc. | Soluble estradiol capsule for vaginal insertion |
JP2017516768A (ja) | 2014-05-22 | 2017-06-22 | セラピューティックスエムディー インコーポレーテッドTherapeuticsmd, Inc. | 天然の併用ホルモン補充療法剤及び療法 |
US9682033B2 (en) | 2015-02-05 | 2017-06-20 | Teva Pharmaceuticals International Gmbh | Methods of treating postherpetic neuralgia with a topical formulation of a spiro-oxindole compound |
US10328087B2 (en) | 2015-07-23 | 2019-06-25 | Therapeuticsmd, Inc. | Formulations for solubilizing hormones |
US10286077B2 (en) | 2016-04-01 | 2019-05-14 | Therapeuticsmd, Inc. | Steroid hormone compositions in medium chain oils |
KR20180126582A (ko) | 2016-04-01 | 2018-11-27 | 쎄러퓨틱스엠디, 인코퍼레이티드 | 스테로이드 호르몬 약제학적 조성물 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6462032B1 (en) * | 1999-05-04 | 2002-10-08 | Wyeth | Cyclic regimens utilizing indoline derivatives |
US6391907B1 (en) * | 1999-05-04 | 2002-05-21 | American Home Products Corporation | Indoline derivatives |
US6407101B1 (en) * | 1999-05-04 | 2002-06-18 | American Home Products Corporation | Cyanopyrroles |
GT200500185A (es) * | 2004-08-09 | 2006-04-10 | Moduladores del receptor de progesterona que comprenden derivados de pirrol-oxindol y sus usos |
-
2005
- 2005-07-04 GT GT200500183A patent/GT200500183A/es unknown
- 2005-07-06 CN CNA2005800268033A patent/CN101001625A/zh active Pending
- 2005-07-06 RU RU2007101304/15A patent/RU2007101304A/ru unknown
- 2005-07-06 AU AU2005277879A patent/AU2005277879A1/en not_active Abandoned
- 2005-07-06 TW TW094122833A patent/TW200605882A/zh unknown
- 2005-07-06 PA PA20058638701A patent/PA8638701A1/es unknown
- 2005-07-06 BR BRPI0514196-6A patent/BRPI0514196A/pt not_active Application Discontinuation
- 2005-07-06 EP EP05771545A patent/EP1778222A1/en not_active Withdrawn
- 2005-07-06 JP JP2007525615A patent/JP2008509216A/ja active Pending
- 2005-07-06 KR KR1020077001433A patent/KR20070039925A/ko not_active Application Discontinuation
- 2005-07-06 MX MX2007001614A patent/MX2007001614A/es not_active Application Discontinuation
- 2005-07-06 WO PCT/US2005/023782 patent/WO2006023107A1/en active Application Filing
- 2005-07-06 CA CA002573310A patent/CA2573310A1/en not_active Abandoned
- 2005-07-06 AR ARP050102806A patent/AR049708A1/es unknown
- 2005-07-06 US US11/175,457 patent/US20060030615A1/en not_active Abandoned
- 2005-07-06 PE PE2005000784A patent/PE20060555A1/es not_active Application Discontinuation
-
2007
- 2007-01-25 IL IL180955A patent/IL180955A0/en unknown
- 2007-02-08 NO NO20070723A patent/NO20070723L/no not_active Application Discontinuation
- 2007-02-08 ZA ZA200701156A patent/ZA200701156B/xx unknown
- 2007-02-09 EC EC2007007236A patent/ECSP077236A/es unknown
Also Published As
Publication number | Publication date |
---|---|
AU2005277879A1 (en) | 2006-03-02 |
CN101001625A (zh) | 2007-07-18 |
PE20060555A1 (es) | 2006-06-26 |
GT200500183A (es) | 2006-04-10 |
US20060030615A1 (en) | 2006-02-09 |
TW200605882A (en) | 2006-02-16 |
KR20070039925A (ko) | 2007-04-13 |
JP2008509216A (ja) | 2008-03-27 |
EP1778222A1 (en) | 2007-05-02 |
WO2006023107A1 (en) | 2006-03-02 |
RU2007101304A (ru) | 2008-09-20 |
MX2007001614A (es) | 2007-04-10 |
ECSP077236A (es) | 2007-03-29 |
PA8638701A1 (es) | 2006-06-02 |
ZA200701156B (en) | 2008-08-27 |
CA2573310A1 (en) | 2006-03-02 |
AR049708A1 (es) | 2006-08-30 |
NO20070723L (no) | 2007-05-07 |
IL180955A0 (en) | 2007-07-04 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |