BRPI0512806A - métodos envolvendo sintase de prostaglandina e2 microssomal - Google Patents

métodos envolvendo sintase de prostaglandina e2 microssomal

Info

Publication number
BRPI0512806A
BRPI0512806A BRPI0512806-4A BRPI0512806A BRPI0512806A BR PI0512806 A BRPI0512806 A BR PI0512806A BR PI0512806 A BRPI0512806 A BR PI0512806A BR PI0512806 A BRPI0512806 A BR PI0512806A
Authority
BR
Brazil
Prior art keywords
synthase
methods involving
microsomal prostaglandin
microsomal
prostaglandin
Prior art date
Application number
BRPI0512806-4A
Other languages
English (en)
Inventor
Yang Cao
Stephen Ayers
Jeffrey Stephen Sabol
Original Assignee
Aventis Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc
Publication of BRPI0512806A publication Critical patent/BRPI0512806A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/88—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving prostaglandins or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/99—Isomerases (5.)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/10—Screening for compounds of potential therapeutic value involving cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

MéTODOS ENVOLVENDO SINTASE DE PROSTA-GLANDINA E2 MICROSSOMAL. A presente invenção refere-se a métodos de determinação da atividade farmacológica, especificidade e toxicidade de inibidores de sintase de prostaglandina E2 microssomal, cujos inibidores são providos e utilizam um sistema de ensaio baseado em célula.
BRPI0512806-4A 2004-06-30 2005-06-24 métodos envolvendo sintase de prostaglandina e2 microssomal BRPI0512806A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US58445904P 2004-06-30 2004-06-30
PCT/US2005/022365 WO2006012259A1 (en) 2004-06-30 2005-06-24 Methods involving micromosal prostaglandin e2 synthase

Publications (1)

Publication Number Publication Date
BRPI0512806A true BRPI0512806A (pt) 2008-04-08

Family

ID=35385902

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0512806-4A BRPI0512806A (pt) 2004-06-30 2005-06-24 métodos envolvendo sintase de prostaglandina e2 microssomal

Country Status (14)

Country Link
US (1) US7132256B2 (pt)
EP (1) EP1779118B1 (pt)
JP (1) JP4746616B2 (pt)
KR (1) KR101178144B1 (pt)
CN (1) CN1977170B (pt)
AT (1) ATE423977T1 (pt)
AU (1) AU2005267227B2 (pt)
BR (1) BRPI0512806A (pt)
CA (1) CA2571927C (pt)
DE (1) DE602005012965D1 (pt)
DK (1) DK1779118T3 (pt)
ES (1) ES2322659T3 (pt)
IL (1) IL180265A0 (pt)
WO (1) WO2006012259A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102495219A (zh) * 2011-12-15 2012-06-13 苏州苏大赛尔免疫生物技术有限公司 前列腺素e2酶联免疫测定试剂盒

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030157084A1 (en) 2001-08-24 2003-08-21 Per-Johan Jakobsson Methods for preparing purified prostaglandin E synthase
KR20050035885A (ko) 2002-08-16 2005-04-19 아벤티스 파마슈티칼스 인크. 마이크로솜성 프로스타글란딘 ｅ 신타제 또는 조혈성 프로스타글란딘 ｄ 신타제의 활성을 감소시키는 능력에 대해 화합물 또는 제제를 검정하는 방법

Also Published As

Publication number Publication date
KR101178144B1 (ko) 2012-08-29
US7132256B2 (en) 2006-11-07
EP1779118B1 (en) 2009-02-25
IL180265A0 (en) 2007-07-04
CA2571927C (en) 2010-04-27
AU2005267227B2 (en) 2010-04-22
DK1779118T3 (da) 2009-06-15
JP2008504817A (ja) 2008-02-21
US20060024663A1 (en) 2006-02-02
EP1779118A1 (en) 2007-05-02
WO2006012259A1 (en) 2006-02-02
ATE423977T1 (de) 2009-03-15
CA2571927A1 (en) 2006-02-02
CN1977170A (zh) 2007-06-06
CN1977170B (zh) 2012-05-23
DE602005012965D1 (de) 2009-04-09
AU2005267227A1 (en) 2006-02-02
ES2322659T3 (es) 2009-06-24
KR20070039504A (ko) 2007-04-12
JP4746616B2 (ja) 2011-08-10

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Legal Events

Date Code Title Description
B25G Requested change of headquarter approved

Owner name: AVENTIS PHARMACEUTICALS, INC. (US)

Free format text: SEDE ALTERADA CONFORME SOLICITADO NA PETICAO NO 020070165509/RJ DE 23/11/2007.

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 11A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2385 DE 20-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.