BRPI0418038A - hidrogenação catalìtica de nitrilos para produzir derivados de capsaicinóide e compostos de amina, e métodos para a purificação e obtenção dos seus polimorfos - Google Patents
hidrogenação catalìtica de nitrilos para produzir derivados de capsaicinóide e compostos de amina, e métodos para a purificação e obtenção dos seus polimorfosInfo
- Publication number
- BRPI0418038A BRPI0418038A BRPI0418038-0A BRPI0418038A BRPI0418038A BR PI0418038 A BRPI0418038 A BR PI0418038A BR PI0418038 A BRPI0418038 A BR PI0418038A BR PI0418038 A BRPI0418038 A BR PI0418038A
- Authority
- BR
- Brazil
- Prior art keywords
- amine
- polymorphs
- purifying
- obtaining
- produce
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- C07C235/34—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton containing six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
"HIDROGENAçãO CATALìTICA DE NITRILOS PARA PRODUZIR DERIVADOS DE CAPSAICINóIDE E COMPOSTOS DE AMINA, E MéTODOS PARA A PURIFICAçãO E OBTENçãO DOS SEUS POLIMORFOS". Processos para a preparação de um composto de amina por cataliticamente hidrogenar um composto de nitrila precursor. Em um aspecto particular, o presente processo de hidrogenação ocorre em um solvente orgânico dipolar na presença de um catalisador de paládio/carbono e um ácido prótico anídrico forte. Em um outro aspecto, a modalidade preferida diz respeito a um processo para a desproteção de um composto para produzir um composto de amina. Em mais um outro aspecto, a modalidade preferida diz respeito aos produtos de amina produzidos pelos presentes processos. Estes produtos de amina podem ser usados para uma variedade de propósitos.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US53098503P | 2003-12-22 | 2003-12-22 | |
PCT/US2004/028153 WO2005068414A1 (en) | 2003-12-22 | 2004-09-27 | Catalytic hydrogenation of nitriles to produce capsaicinoid derivatives and amine compounds, and methods for purifiying and obtaining the polymorphs thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0418038A true BRPI0418038A (pt) | 2007-04-17 |
Family
ID=34794216
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0418038-0A BRPI0418038A (pt) | 2003-12-22 | 2004-09-27 | hidrogenação catalìtica de nitrilos para produzir derivados de capsaicinóide e compostos de amina, e métodos para a purificação e obtenção dos seus polimorfos |
Country Status (5)
Country | Link |
---|---|
US (1) | US20060047171A1 (pt) |
EP (1) | EP1697303A4 (pt) |
BR (1) | BRPI0418038A (pt) |
CA (1) | CA2551128A1 (pt) |
WO (1) | WO2005068414A1 (pt) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2285774B1 (en) | 2008-06-05 | 2015-02-25 | Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. | Novel modulators of protein kinase signaling |
EP2654741A1 (en) * | 2010-12-22 | 2013-10-30 | Galderma Research & Development | Modulators and methods for the treatment of rosacea |
US9770454B2 (en) | 2013-07-14 | 2017-09-26 | Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. | IGF-1R signaling pathway inhibitors useful in the treatment of neurodegenerative diseases |
WO2015131019A1 (en) * | 2014-02-28 | 2015-09-03 | The Texas A&M University System | Compositions and methods for inhibition of mycobacteria |
EP3750530A1 (en) | 2015-02-05 | 2020-12-16 | TyrNovo Ltd. | Combinations of irs/stat3 dual modulators and anti-cancer agents for treating cancer |
Family Cites Families (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2740787A (en) * | 1953-05-22 | 1956-04-03 | Charles L Mehltretter | Extraction and recovery of alkaloids |
US3235583A (en) * | 1964-07-22 | 1966-02-15 | Norwich Pharma Co | Preparation of aspirin |
FR1546478A (fr) * | 1967-01-27 | 1968-11-22 | Rhone Poulenc Sa | Nouveaux dérivés de l'acide benzoyl-3 phénylacétique et leur préparation |
US3607941A (en) * | 1968-06-27 | 1971-09-21 | Sterling Drug Inc | 2-(lower-alkoxy)-2-phenylalkanamidoximes |
US3637767A (en) * | 1968-07-30 | 1972-01-25 | Syntex Corp | 2-(6'-methoxynaphth-2'-yl)propylene oxide and 5'-halo derivatives |
US3591584A (en) * | 1968-08-27 | 1971-07-06 | Pfizer | Benzothiazine dioxides |
US4313958A (en) * | 1980-10-24 | 1982-02-02 | The Procter & Gamble Company | Method of producing analgesia |
US4424205A (en) * | 1982-03-18 | 1984-01-03 | The Procter & Gamble Company | Hydroxyphenylacetamides having analgesic and anti-irritant activity |
US5045565A (en) * | 1987-03-09 | 1991-09-03 | The Procter & Gamble Company | Novel compounds, pharmaceutical compositions, and methods for treating inflammation and pain |
US5034560A (en) * | 1990-10-19 | 1991-07-23 | The Standard Oil Company | Synthesis of ethylamines |
US5094782A (en) * | 1990-12-24 | 1992-03-10 | National Science Council Of Republic Of China | Synthesis of capsacin derivatives and their use as an analgesic drug and vessel dilation drug |
US5242944A (en) * | 1991-06-20 | 1993-09-07 | Korea Research Institute Of Chemical Technology | Phenylacetamide derivatives and pharmaceutical compositions thereof |
EP0525360B1 (en) * | 1991-07-30 | 1998-03-25 | Korea Research Institute Of Chemical Technology | Novel phenylacetamide derivatives and processes for the preparation thereof |
US5178879A (en) * | 1992-04-17 | 1993-01-12 | Michael Adekunle | Capsaicin gel |
DE4239782A1 (de) * | 1992-11-26 | 1994-06-01 | Basf Ag | Verfahren zur Herstellung von Diaminen |
KR0147963B1 (ko) * | 1995-01-10 | 1998-08-17 | 강박광 | 엔-아릴알킬페닐아세트아미드 유도체와 그의 제조방법 |
US6166085A (en) * | 1995-04-14 | 2000-12-26 | The Regents Of The University Of California | Method of producing analgesia |
US5849737A (en) * | 1995-04-14 | 1998-12-15 | The Regents Of The University Of California | Compositions and methods for treating pain |
US5849761A (en) * | 1995-09-12 | 1998-12-15 | Regents Of The University Of California | Peripherally active anti-hyperalgesic opiates |
US6573282B1 (en) * | 1995-09-12 | 2003-06-03 | Adolor Corporation | Peripherally active anti-hyperalgesic opiates |
KR0168494B1 (ko) * | 1995-12-12 | 1999-03-20 | 강박광 | N-아릴알킬호모바닐릭아미드 유도체 및 이의 제조방법 |
DE19713383A1 (de) * | 1997-04-01 | 1998-10-08 | Basf Ag | Verfahren zur Herstellung tertiärer Amine aus Nitrilen und sekundären Aminen |
US5847220A (en) * | 1997-06-16 | 1998-12-08 | Air Products And Chemicals, Inc. | Process for hydrogenation of cyanopropionaldehyde-containing cyanopropionaldehyde acetals |
US5869653A (en) * | 1997-10-30 | 1999-02-09 | Air Products And Chemicals, Inc. | Hydrogenation of nitriles to produce amines |
US6156694A (en) * | 1998-11-05 | 2000-12-05 | E. I. Dupont De Nemours & Company | Raney cobalt catalyst and a process for hydrogenating organic compounds using said catalyst |
CN1210254C (zh) * | 1999-02-22 | 2005-07-13 | 株式会社太平洋 | 作为有效的香草类受体激动剂和镇痛药的含有树脂毒素药效基团的香草类类似物,其组合物以及应用 |
CO5210943A1 (es) * | 1999-05-04 | 2002-10-30 | Novartis Ag | Compuestos plaguicidas derivados de triazina, composiciones para el control de plagas que comprenden dicho compuesto y cuando menos un auxiliar y metodos para controlar plagas |
US20010034320A1 (en) * | 2000-01-18 | 2001-10-25 | Hans-Michael Brecht | NK1-receptor antagonists for treating restless legs syndrome |
US6399830B1 (en) * | 2000-12-13 | 2002-06-04 | Air Products And Chemicals, Inc. | Selective reductive amination of nitriles |
-
2004
- 2004-08-27 US US10/927,493 patent/US20060047171A1/en not_active Abandoned
- 2004-09-27 BR BRPI0418038-0A patent/BRPI0418038A/pt not_active Application Discontinuation
- 2004-09-27 EP EP04782593A patent/EP1697303A4/en not_active Withdrawn
- 2004-09-27 WO PCT/US2004/028153 patent/WO2005068414A1/en active Application Filing
- 2004-09-27 CA CA002551128A patent/CA2551128A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1697303A1 (en) | 2006-09-06 |
US20060047171A1 (en) | 2006-03-02 |
EP1697303A4 (en) | 2007-07-04 |
CA2551128A1 (en) | 2005-07-28 |
WO2005068414A1 (en) | 2005-07-28 |
WO2005068414A8 (en) | 2005-09-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
B11Y | Definitive dismissal acc. article 33 of ipl - extension of time limit for request of examination expired |