BRPI0413446A - gel bioadesivo á base de hidroxietilcelulose - Google Patents

gel bioadesivo á base de hidroxietilcelulose

Info

Publication number
BRPI0413446A
BRPI0413446A BRPI0413446-0A BRPI0413446A BRPI0413446A BR PI0413446 A BRPI0413446 A BR PI0413446A BR PI0413446 A BRPI0413446 A BR PI0413446A BR PI0413446 A BRPI0413446 A BR PI0413446A
Authority
BR
Brazil
Prior art keywords
hydroxyethylcellulose
bioadhesive gel
bioadhesive
gel
adheres
Prior art date
Application number
BRPI0413446-0A
Other languages
English (en)
Inventor
Massimo Prini
Original Assignee
Mipharm S P A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mipharm S P A filed Critical Mipharm S P A
Publication of BRPI0413446A publication Critical patent/BRPI0413446A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Urology & Nephrology (AREA)
  • Inorganic Chemistry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Anesthesiology (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

"GEL BIOADESIVO à BASE DE HIDROXIETILCELULOSE". A presente invenção refere-se a composições na forma de um gel bioadesivo, que adere às membranas mucosas, em particular à mucosa vaginal, para a aplicação de ingredientes e/ou princípios ativos, compreendendo hidroxietilcelulose como o único agente geleificante.
BRPI0413446-0A 2003-08-08 2004-07-30 gel bioadesivo á base de hidroxietilcelulose BRPI0413446A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT001640A ITMI20031640A1 (it) 2003-08-08 2003-08-08 Base per gel bioadesivi.
PCT/EP2004/008577 WO2005014047A1 (en) 2003-08-08 2004-07-30 Bioadhesive gel based on hydroxyethylcellulose

Publications (1)

Publication Number Publication Date
BRPI0413446A true BRPI0413446A (pt) 2006-10-17

Family

ID=34131212

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0413446-0A BRPI0413446A (pt) 2003-08-08 2004-07-30 gel bioadesivo á base de hidroxietilcelulose

Country Status (16)

Country Link
US (2) US20070031479A1 (pt)
EP (1) EP1651274B1 (pt)
JP (1) JP4855935B2 (pt)
CN (1) CN1832760B (pt)
AT (1) ATE395084T1 (pt)
BR (1) BRPI0413446A (pt)
CA (1) CA2535123C (pt)
CY (1) CY1108548T1 (pt)
DE (1) DE602004013787D1 (pt)
DK (1) DK1651274T3 (pt)
ES (1) ES2305818T3 (pt)
IT (1) ITMI20031640A1 (pt)
PL (1) PL1651274T3 (pt)
PT (1) PT1651274E (pt)
SI (1) SI1651274T1 (pt)
WO (1) WO2005014047A1 (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100394919C (zh) * 2006-03-01 2008-06-18 杨军 一种用于治疗阴道疾病的药物组合物
US8433851B2 (en) 2007-08-16 2013-04-30 International Business Machines Corporation Reducing wiring congestion in a cache subsystem utilizing sectored caches with discontiguous addressing
US9446131B2 (en) 2013-01-31 2016-09-20 Merz Pharmaceuticals, Llc Topical compositions and methods for making and using same
US9433680B2 (en) 2013-01-31 2016-09-06 Merz Pharmaceuticals, Llc Topical compositions and methods for making and using same
US8778365B1 (en) 2013-01-31 2014-07-15 Merz Pharmaceuticals, Llc Topical compositions and methods for making and using same
US9452173B2 (en) 2013-01-31 2016-09-27 Merz Pharmaceuticals, Llc Topical compositions and methods for making and using same
CN106310266A (zh) * 2015-07-09 2017-01-11 王强 一种预防或治疗粘膜疾病的组合物及制备方法
CN106038477A (zh) * 2016-06-14 2016-10-26 上海通用药业股份有限公司 一种含有噻康唑的阴道用凝胶的制备方法
CN106109398A (zh) * 2016-06-14 2016-11-16 上海通用药业股份有限公司 一种含有噻康唑的阴道用凝胶
KR20190026686A (ko) * 2016-07-08 2019-03-13 아지엔드 키미쉐 리유나이트 안젤리니 프란체스코 에이.씨.알.에이.에프. 에스.피.에이 벤지다민을 포함하는 약학적 조성물
IT201900000388A1 (it) * 2019-01-10 2020-07-10 L N Age S R L Composizione per l'uso nel trattamento di lesioni vaginali, del glande ed anali
EP3986378A1 (en) * 2019-06-21 2022-04-27 Alfasigma S.p.A. Pharmaceutical compositions in the form of gel containing xyloglucan and alcohols for the controlled release of active ingredients
CN111557897B (zh) * 2020-07-07 2023-06-23 温州海鹤药业有限公司 一种含有硝呋太尔的药物组合物及其制备方法

Family Cites Families (22)

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Publication number Priority date Publication date Assignee Title
DE3731255A1 (de) * 1987-09-17 1989-04-06 Boehringer Ingelheim Int Stabilisierung von therapeutisch wirksamen proteinen in pharmazeutischen zubereitungen
DE3741149A1 (de) * 1987-12-04 1989-06-15 Thomae Gmbh Dr K Zubereitungsformen zur verhinderung von adhaesionen von organen und organteilen
JPH04217925A (ja) * 1990-03-27 1992-08-07 Nippon Saafuakutanto Kogyo Kk 新規な解熱消炎鎮痛剤組成物
JPH05178763A (ja) * 1991-02-19 1993-07-20 Nippon Saafuakutanto Kogyo Kk 難溶解性薬物溶解剤組成物
US5667492A (en) 1994-10-07 1997-09-16 Columbia Laboratories, Inc. Use and composition of an anti-sexually transmitted diseases formulation
AT408067B (de) * 1995-03-17 2001-08-27 Gebro Pharma Gmbh Pharmazeutische zusammensetzung zur topischen applizierung und verfahren zu ihrer herstellung
US5849761A (en) * 1995-09-12 1998-12-15 Regents Of The University Of California Peripherally active anti-hyperalgesic opiates
JP3616688B2 (ja) * 1996-03-25 2005-02-02 太田製薬株式会社 医薬組成物
WO1997047292A1 (en) * 1996-06-12 1997-12-18 The Procter & Gamble Company Use of h2-antagonists for the manufacture of a topical composition for the treatment of colds
IT1284874B1 (it) 1996-08-02 1998-05-22 Farmigea Spa Complessi bioadesivi di polycarbophil e farmaci antifungini o antiprotozoari azolici
US5871715A (en) * 1997-02-28 1999-02-16 Gillette Canada Inc. Stannous fluoride gel with improved stand-up
CA2289966A1 (en) * 1997-05-14 1998-11-19 Galen (Chemicals) Limited Topical compositions
US6416779B1 (en) 1997-06-11 2002-07-09 Umd, Inc. Device and method for intravaginal or transvaginal treatment of fungal, bacterial, viral or parasitic infections
WO2000015192A1 (en) 1998-09-17 2000-03-23 Zonagen, Inc. Methods and materials related to bioadhesive contraceptive gels
US6159491A (en) 1999-02-12 2000-12-12 Biovector Technologies, Inc. Prolonged release bioadhesive vaginal gel dosage form
CA2386422A1 (en) * 1999-10-22 2001-04-26 Lif-Hlaup Ehf. Bio-Gels Pharmaceuticals Inc. Pharmaceutical composition for treatment of mucosal epithelial ulceration and/or erosion
FR2802097B1 (fr) 1999-12-14 2002-12-13 Invest S Therapeutiques Essais Composition sous forme de gel prevue pour recevoir un principe actif en solution ou en suspension, notamment pour application sur une muqueuse et procede de fabrication
WO2002011768A1 (en) * 2000-08-03 2002-02-14 Antares Pharma Ipl Ag Novel composition for transdermal and/or transmucosal administration of active compounds that ensures adequate therapeutic levels
IL142037A0 (en) * 2001-03-15 2002-03-10 Agis Ind 1983 Ltd Pharmaceutical compositions containing a non-steroidal anti-inflammatory drug
CA2457526A1 (en) * 2001-08-29 2003-03-13 Umd, Inc. Vaginal delivery of chemotherapeutic agents and inhibitors of membrane efflux systems for cancer therapy
JP4651944B2 (ja) * 2002-02-07 2011-03-16 ザ トラスティース オブ コロンビア ユニバーシティ イン ザ シティ オブ ニューヨーク 殺精子剤および殺菌剤からの粘膜刺激の予防のための亜鉛塩組成物
AR039540A1 (es) * 2002-05-13 2005-02-23 Tibotec Pharm Ltd Compuestos microbicidas con contenido de pirimidina o triazina

Also Published As

Publication number Publication date
US8790685B2 (en) 2014-07-29
ATE395084T1 (de) 2008-05-15
EP1651274A1 (en) 2006-05-03
JP2007533604A (ja) 2007-11-22
CY1108548T1 (el) 2014-04-09
CN1832760B (zh) 2010-06-23
US20070031479A1 (en) 2007-02-08
ITMI20031640A1 (it) 2005-02-09
DE602004013787D1 (de) 2008-06-26
CA2535123C (en) 2012-06-26
PT1651274E (pt) 2008-08-11
CA2535123A1 (en) 2005-02-17
CN1832760A (zh) 2006-09-13
EP1651274B1 (en) 2008-05-14
PL1651274T3 (pl) 2008-10-31
US20120083515A1 (en) 2012-04-05
ES2305818T3 (es) 2008-11-01
SI1651274T1 (sl) 2008-10-31
DK1651274T3 (da) 2008-09-08
WO2005014047A1 (en) 2005-02-17
JP4855935B2 (ja) 2012-01-18

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Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: MITECH-IDEA S.R.L. (IT)

Free format text: TRANSFERIDO DE: MIPHARM S.P.A.

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: PARA: INT. CL. A61K 47/38; A61P 15/00

Ipc: A61K 47/38 (2011.01), A61P 15/00 (2011.01)

B25A Requested transfer of rights approved

Owner name: MIPHARM S.P.A. (IT)

B25H Request for change of headquarter rejected

Owner name: MIPHARM S.P.A. (IT)

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL