BRPI0412861A - compostos de nicotinamida usados como inibidores da pde4 - Google Patents
compostos de nicotinamida usados como inibidores da pde4Info
- Publication number
- BRPI0412861A BRPI0412861A BRPI0412861-3A BRPI0412861A BRPI0412861A BR PI0412861 A BRPI0412861 A BR PI0412861A BR PI0412861 A BRPI0412861 A BR PI0412861A BR PI0412861 A BRPI0412861 A BR PI0412861A
- Authority
- BR
- Brazil
- Prior art keywords
- compounds used
- pde4 inhibitors
- nicotinamide compounds
- nicotinamide
- preparation
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
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- A—HUMAN NECESSITIES
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- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A61P31/14—Antivirals for RNA viruses
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P9/00—Drugs for disorders of the cardiovascular system
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- A—HUMAN NECESSITIES
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- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Diabetes (AREA)
- Oncology (AREA)
- Cardiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Hematology (AREA)
- Communicable Diseases (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Virology (AREA)
- Psychology (AREA)
- Epidemiology (AREA)
- Hospice & Palliative Care (AREA)
- Dermatology (AREA)
- Endocrinology (AREA)
- AIDS & HIV (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0317471.1A GB0317471D0 (en) | 2003-07-25 | 2003-07-25 | Novel compounds |
| PCT/IB2004/002370 WO2005009438A1 (en) | 2003-07-25 | 2004-07-13 | Nicotinamide compounds useful as pde4 inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BRPI0412861A true BRPI0412861A (pt) | 2006-10-03 |
Family
ID=27772705
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0412861-3A BRPI0412861A (pt) | 2003-07-25 | 2004-07-13 | compostos de nicotinamida usados como inibidores da pde4 |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP1653958A1 (ja) |
| JP (1) | JP2006528658A (ja) |
| BR (1) | BRPI0412861A (ja) |
| CA (1) | CA2536383A1 (ja) |
| GB (1) | GB0317471D0 (ja) |
| MX (1) | MXPA06001038A (ja) |
| WO (1) | WO2005009438A1 (ja) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR049384A1 (es) | 2004-05-24 | 2006-07-26 | Glaxo Group Ltd | Derivados de purina |
| GB0514809D0 (en) | 2005-07-19 | 2005-08-24 | Glaxo Group Ltd | Compounds |
| CN101365700A (zh) | 2005-11-15 | 2009-02-11 | 沃泰克斯药物股份有限公司 | 可用作激酶抑制剂的氮杂吲唑 |
| CN102105448B (zh) * | 2008-05-27 | 2013-11-13 | 阿斯利康(瑞典)有限公司 | 苯氧基吡啶基酰胺衍生物和它们在治疗由pde4介导的病症中的用途 |
| CN111875594A (zh) * | 2020-07-21 | 2020-11-03 | 中国药科大学 | 具有磷酸二酯酶4b抑制活性的吲唑杂环类化合物 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ID22781A (id) * | 1997-04-04 | 1999-12-09 | Pfizer Prod Inc | Turunan-turunan nikotinamida |
| CA2398182C (en) * | 2000-01-31 | 2007-03-13 | Pfizer Products Inc. | Nicotinamide benzofused-heterocyclyl derivatives useful as selective inhibitors of pde4 isozymes |
| OA12541A (en) * | 2001-01-31 | 2006-06-05 | Pfizer Prod Inc | Ether derivatives useful as inhibitors of PDE4 isozymes. |
| JP4583761B2 (ja) * | 2002-02-11 | 2010-11-17 | ファイザー・インク | Ｐｄｅ４阻害剤として有用なニコチンアミド誘導体 |
-
2003
- 2003-07-25 GB GBGB0317471.1A patent/GB0317471D0/en not_active Ceased
-
2004
- 2004-07-13 JP JP2006521683A patent/JP2006528658A/ja active Pending
- 2004-07-13 EP EP04744029A patent/EP1653958A1/en not_active Withdrawn
- 2004-07-13 MX MXPA06001038A patent/MXPA06001038A/es unknown
- 2004-07-13 BR BRPI0412861-3A patent/BRPI0412861A/pt not_active IP Right Cessation
- 2004-07-13 WO PCT/IB2004/002370 patent/WO2005009438A1/en active Application Filing
- 2004-07-13 CA CA002536383A patent/CA2536383A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2006528658A (ja) | 2006-12-21 |
| WO2005009438A1 (en) | 2005-02-03 |
| GB0317471D0 (en) | 2003-08-27 |
| EP1653958A1 (en) | 2006-05-10 |
| CA2536383A1 (en) | 2005-02-03 |
| MXPA06001038A (es) | 2006-04-24 |
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| B08K | Lapse as no evidence of payment of the annual fee has been furnished to inpi (acc. art. 87) |
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