BRPI0410558A - processo para a preparação de emulsões oleosas isotÈnicas, emulsão oleosa isotÈnica, uso da mesma, e, processos para reposição de hormÈnio em bebês prematuros, e para o tratamento de danos neurológicos após derrames - Google Patents

processo para a preparação de emulsões oleosas isotÈnicas, emulsão oleosa isotÈnica, uso da mesma, e, processos para reposição de hormÈnio em bebês prematuros, e para o tratamento de danos neurológicos após derrames

Info

Publication number
BRPI0410558A
BRPI0410558A BRPI0410558-3A BRPI0410558A BRPI0410558A BR PI0410558 A BRPI0410558 A BR PI0410558A BR PI0410558 A BRPI0410558 A BR PI0410558A BR PI0410558 A BRPI0410558 A BR PI0410558A
Authority
BR
Brazil
Prior art keywords
isotonic
oily
hormone replacement
processes
preparation
Prior art date
Application number
BRPI0410558-3A
Other languages
English (en)
Inventor
Sonja Broemer
Joerg Nehne
Frank Pohlandt
Original Assignee
Braun Melsungen Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Braun Melsungen Ag filed Critical Braun Melsungen Ag
Publication of BRPI0410558A publication Critical patent/BRPI0410558A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34—Gestagens

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)

Abstract

"PROCESSO PARA A PREPARAçãO DE EMULSõES OLEOSAS ISOTÈNICAS, EMULSãO OLEOSA ISOTÈNICA, USO DA MESMA, E, PROCESSOS PARA REPOSIçãO DE HORMÈNIO EM BEBêS PREMATUROS, E PARA O TRATAMENTO DE DANOS NEUROLóGICOS APóS DERRAMES". A invenção refere-se a um processo para a produção de emulsões oleosas (emulsões de lipídio) que contém hormónio, a uma emulsão oleosa isotónica que pode ser obtida pelo dito processo e ao uso da dita emulsão para a produção de um medicamento para administração intravenosa, em particular, para reposição pós-parto de hormónio em bebês prematuros e para o tratamento de danos neurológicos após isquemia cerebral.
BRPI0410558-3A 2003-06-18 2004-06-15 processo para a preparação de emulsões oleosas isotÈnicas, emulsão oleosa isotÈnica, uso da mesma, e, processos para reposição de hormÈnio em bebês prematuros, e para o tratamento de danos neurológicos após derrames BRPI0410558A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03013790A EP1488785A1 (de) 2003-06-18 2003-06-18 Ölemulsion zur postnatalen Hormonsubstitution
PCT/EP2004/051114 WO2004110402A1 (de) 2003-06-18 2004-06-15 Ölemulsion zur postnatalen hormonsubstitution

Publications (1)

Publication Number Publication Date
BRPI0410558A true BRPI0410558A (pt) 2006-06-20

Family

ID=33395816

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0410558-3A BRPI0410558A (pt) 2003-06-18 2004-06-15 processo para a preparação de emulsões oleosas isotÈnicas, emulsão oleosa isotÈnica, uso da mesma, e, processos para reposição de hormÈnio em bebês prematuros, e para o tratamento de danos neurológicos após derrames

Country Status (14)

Country Link
US (1) US20070071777A1 (pt)
EP (2) EP1488785A1 (pt)
JP (1) JP2006527736A (pt)
CN (1) CN1809339B (pt)
AT (1) ATE359061T1 (pt)
BR (1) BRPI0410558A (pt)
CA (1) CA2526567A1 (pt)
DE (1) DE502004003483D1 (pt)
ES (1) ES2281813T3 (pt)
MX (1) MXPA05012411A (pt)
PL (1) PL1633325T3 (pt)
PT (1) PT1633325E (pt)
RU (1) RU2318494C2 (pt)
WO (1) WO2004110402A1 (pt)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2378117T3 (es) * 2007-06-21 2012-04-09 Pantarhei Bioscience B.V. Tratamiento del Síndrome de aspiración de meconio con estrógenos
CA2738630A1 (en) * 2008-10-10 2010-04-15 Dara Biosciences, Inc. Methods for treating or preventing pain using spicamycin derivatives
US9034389B2 (en) * 2009-03-11 2015-05-19 Stable Solutions Llc Omega-3 enriched fish oil-in-water parenteral nutrition emulsions
US8993625B2 (en) 2009-03-11 2015-03-31 Stable Solutions Llc Method of mitigating adverse drug events using omega-3 fatty acids as a parenteral therapeutic drug vehicle
WO2011103514A1 (en) * 2010-02-18 2011-08-25 Martek Biosciences Corporation Dha triglyceride emulsions
US20110200645A1 (en) * 2010-02-18 2011-08-18 Martek Biosciences Corporation DHA Free Fatty Acid Emulsions
WO2011103510A1 (en) * 2010-02-18 2011-08-25 Martek Biosciences Corporation Dha ester emulsions
CA2789238C (en) * 2010-03-09 2020-05-12 Dignity Health Methods for inhibiting preterm labor and uterine contractility disorders and preventing cervical ripening
TW201138782A (en) * 2010-04-26 2011-11-16 Besins Healthcare Lu Sarl Low-oil pharmaceutical emulsion compositions comprising progestogen
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
HRP20211377T1 (hr) 2011-11-23 2022-01-07 Therapeuticsmd, Inc. Prirodne kombinirane hormonske supstitucijske formulacije i terapije
TW201334808A (zh) * 2012-02-29 2013-09-01 Braun Melsungen Ag 含有荷爾蒙之包含磷蝦磷脂質的乳劑
EP2819650A1 (en) * 2012-02-29 2015-01-07 B. Braun Melsungen AG Hormone containing emulsion comprising krill phospholipids
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
CA2947767A1 (en) 2014-05-22 2015-11-26 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
CN106852118A (zh) * 2014-09-19 2017-06-13 赫伦治疗有限公司 阿瑞吡坦乳剂制剂
US9974742B2 (en) 2016-02-01 2018-05-22 Heron Therapeutics, Inc. Emulsion formulations of an NK-1 receptor antagonist and uses thereof
US10285998B1 (en) 2018-04-04 2019-05-14 The Menopause Method, Inc. Composition and method to aid in hormone replacement therapy
US11633405B2 (en) 2020-02-07 2023-04-25 Therapeuticsmd, Inc. Steroid hormone pharmaceutical formulations

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60258110A (ja) * 1984-06-05 1985-12-20 Daigo Eiyou Kagaku Kk 静脈注射可能なプロゲステロン乳化注射液
CA2013755C (en) * 1989-04-05 1993-11-30 Simon Benita Medicinal emulsions
CN1029293C (zh) * 1993-01-01 1995-07-12 浙江省中医院 薏苡仁中性油脂乳剂
SE9301171D0 (sv) * 1993-04-07 1993-04-07 Ab Astra Pharmaceutical composition containing lipophilic drugs
US6267985B1 (en) * 1999-06-30 2001-07-31 Lipocine Inc. Clear oil-containing pharmaceutical compositions
CN1204238C (zh) * 2000-10-18 2005-06-01 李大鹏 从核桃仁中提取的核桃仁油组合物及其药物制剂

Also Published As

Publication number Publication date
CA2526567A1 (en) 2004-12-23
ATE359061T1 (de) 2007-05-15
EP1633325A1 (de) 2006-03-15
AU2004246823A1 (en) 2004-12-23
MXPA05012411A (es) 2006-02-13
CN1809339A (zh) 2006-07-26
RU2006101322A (ru) 2006-06-10
DE502004003483D1 (de) 2007-05-24
PT1633325E (pt) 2007-05-31
RU2318494C2 (ru) 2008-03-10
JP2006527736A (ja) 2006-12-07
CN1809339B (zh) 2010-06-23
ES2281813T3 (es) 2007-10-01
WO2004110402A1 (de) 2004-12-23
US20070071777A1 (en) 2007-03-29
EP1633325B1 (de) 2007-04-11
PL1633325T3 (pl) 2007-08-31
EP1488785A1 (de) 2004-12-22

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: PARA: INT. CL. A61K 9/107, 31/565, 31/57; A61P 5/00, 25/00

Ipc: A61K 9/107 (2011.01), A61K 31/565 (2011.01), A61K

B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]