BRPI0409688A - análise e emprego de polimorfismos par1 para avaliação do risco de doenças cardiovasculares - Google Patents

análise e emprego de polimorfismos par1 para avaliação do risco de doenças cardiovasculares

Info

Publication number
BRPI0409688A
BRPI0409688A BRPI0409688-6A BRPI0409688A BRPI0409688A BR PI0409688 A BRPI0409688 A BR PI0409688A BR PI0409688 A BRPI0409688 A BR PI0409688A BR PI0409688 A BRPI0409688 A BR PI0409688A
Authority
BR
Brazil
Prior art keywords
par1
polymorphisms
analysis
cardiovascular disease
risk assessment
Prior art date
Application number
BRPI0409688-6A
Other languages
English (en)
Inventor
Detlef Kozian
Joerg Czech
Karl-Ernst Siegler
Jean-Francois Deleuze
Sylvain Ricard
Sandrine Mace
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Publication of BRPI0409688A publication Critical patent/BRPI0409688A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)

Abstract

"ANáLISE E EMPREGO DE POLIMORFISMOS PAR1 PARA AVALIAçãO DO RISCO DE DOENçAS CARDIOVASCULARES". A invenção refere-se a sequências de polinucleotídeos abrangendo variações genéticas do gen PAR1 nas posições 3090 e/ou 3329. A existência dessas variantes é correlacionada a homens com elevada susceptibilidade para determinadas doenças cardio-circulatórias. A invenção refere-se além disso a processo para comprovação dessas variações genéticas.
BRPI0409688-6A 2003-04-24 2004-04-16 análise e emprego de polimorfismos par1 para avaliação do risco de doenças cardiovasculares BRPI0409688A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10318496A DE10318496A1 (de) 2003-04-24 2003-04-24 Analyse und Verwendung von PAR 1 Polymorphismen zur Risikoabschätzung für kardiovaskuläre Erkrankungen
PCT/EP2004/004035 WO2004094470A1 (de) 2003-04-24 2004-04-16 Analyse und verwendung von par 1 polymorphismen zur risikoabschätzung für kardiovaskuläre erkrankungen

Publications (1)

Publication Number Publication Date
BRPI0409688A true BRPI0409688A (pt) 2006-04-18

Family

ID=33304897

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0409688-6A BRPI0409688A (pt) 2003-04-24 2004-04-16 análise e emprego de polimorfismos par1 para avaliação do risco de doenças cardiovasculares

Country Status (16)

Country Link
EP (1) EP1622940B1 (pt)
JP (1) JP4728949B2 (pt)
KR (1) KR20060006939A (pt)
CN (1) CN1791613A (pt)
AT (1) ATE407145T1 (pt)
AU (1) AU2004232459B2 (pt)
BR (1) BRPI0409688A (pt)
CA (1) CA2522815A1 (pt)
DE (2) DE10318496A1 (pt)
DK (1) DK1622940T3 (pt)
ES (1) ES2312990T3 (pt)
IL (1) IL171477A (pt)
MX (1) MXPA05011464A (pt)
NO (1) NO20055538L (pt)
RU (1) RU2380422C2 (pt)
WO (1) WO2004094470A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2453606C2 (ru) * 2010-07-16 2012-06-20 Федеральное государственное автономное образовательное учреждение высшего профессионального образования "ЮЖНЫЙ ФЕДЕРАЛЬНЫЙ УНИВЕРСИТЕТ" Способ расширенного скрининга предрасположенности к сердечно-сосудистым заболеваниям и биочип для осуществления этого способа

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2330790A1 (en) * 1998-05-04 1999-11-11 Fraunhofer-Gesellschaft Zur Forderung Der Angewandten Forschung E.V. Method and device for isolating nucleic acids
DE19819889A1 (de) * 1998-05-04 1999-11-11 Fraunhofer Ges Forschung Verfahren zur Isolierung von Nucleinsäuren
US6322980B1 (en) * 1999-04-30 2001-11-27 Aclara Biosciences, Inc. Single nucleotide detection using degradation of a fluorescent sequence

Also Published As

Publication number Publication date
AU2004232459A1 (en) 2004-11-04
KR20060006939A (ko) 2006-01-20
CA2522815A1 (en) 2004-11-04
WO2004094470A1 (de) 2004-11-04
EP1622940A1 (de) 2006-02-08
DE10318496A1 (de) 2004-11-25
ATE407145T1 (de) 2008-09-15
RU2005136430A (ru) 2006-04-20
NO20055538L (no) 2005-11-23
IL171477A (en) 2010-11-30
JP2007534293A (ja) 2007-11-29
DE502004007990D1 (de) 2008-10-16
CN1791613A (zh) 2006-06-21
RU2380422C2 (ru) 2010-01-27
EP1622940B1 (de) 2008-09-03
ES2312990T3 (es) 2009-03-01
DK1622940T3 (da) 2009-01-12
JP4728949B2 (ja) 2011-07-20
MXPA05011464A (es) 2006-03-08
AU2004232459B2 (en) 2010-11-11

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B10A Cessation: cessation confirmed

Free format text: HOMOLOGADA A DESISTENCIA DO PEDIDO, SOLICITADA ATRAVES DA PETICAO NO 020120004052/RJ DE 16/01/2012.