BR9914254A - Composição para o tratamento de doença de degeneração retinal lesada por luz - Google Patents
Composição para o tratamento de doença de degeneração retinal lesada por luzInfo
- Publication number
- BR9914254A BR9914254A BR9914254-6A BR9914254A BR9914254A BR 9914254 A BR9914254 A BR 9914254A BR 9914254 A BR9914254 A BR 9914254A BR 9914254 A BR9914254 A BR 9914254A
- Authority
- BR
- Brazil
- Prior art keywords
- treatment
- light
- composition
- retinal degeneration
- degeneration disease
- Prior art date
Links
- 201000007737 Retinal degeneration Diseases 0.000 title abstract 4
- 230000004258 retinal degeneration Effects 0.000 title abstract 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- 206010025421 Macule Diseases 0.000 abstract 2
- 230000007850 degeneration Effects 0.000 abstract 2
- UIAGMCDKSXEBJQ-IBGZPJMESA-N 3-o-(2-methoxyethyl) 5-o-propan-2-yl (4s)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate Chemical compound COCCOC(=O)C1=C(C)NC(C)=C(C(=O)OC(C)C)[C@H]1C1=CC=CC([N+]([O-])=O)=C1 UIAGMCDKSXEBJQ-IBGZPJMESA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 229940127292 dihydropyridine calcium channel blocker Drugs 0.000 abstract 1
- 230000000938 luteal effect Effects 0.000 abstract 1
- 229960000715 nimodipine Drugs 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10297298P | 1998-10-02 | 1998-10-02 | |
| US11070098P | 1998-12-03 | 1998-12-03 | |
| PCT/JP1999/005321 WO2000020002A1 (en) | 1998-10-02 | 1999-09-29 | Composition for treatment of light-injured retinal degeneration disease |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9914254A true BR9914254A (pt) | 2001-07-03 |
Family
ID=26799937
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9914254-6A BR9914254A (pt) | 1998-10-02 | 1999-09-29 | Composição para o tratamento de doença de degeneração retinal lesada por luz |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6248759B1 (https=) |
| EP (1) | EP1117404A1 (https=) |
| JP (1) | JP2002526409A (https=) |
| AR (1) | AR020681A1 (https=) |
| AU (1) | AU5998399A (https=) |
| BR (1) | BR9914254A (https=) |
| CA (1) | CA2346086A1 (https=) |
| WO (1) | WO2000020002A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2005204391A1 (en) * | 2004-01-14 | 2005-07-28 | Lavipharm Laboratories, Inc. | Transdermal delivery device for dihydropyridine type calcium antagonists containing at least one fatty acid |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2585574B1 (fr) * | 1985-07-31 | 1988-09-09 | Corbiere Jerome | Nouvelles compositions pharmaceutiques anti-glaucomateuses a base de 1,4-dihydropyridines et leur procede d'obtention |
| WO1990006123A1 (en) * | 1988-12-05 | 1990-06-14 | Houston Biotechnology Incorporated | Therapeutic use of calcium entry blockers in retinal or optic nerve dysfunction |
| FR2642307A1 (fr) * | 1989-01-27 | 1990-08-03 | Corbiere Jerome | Medicament pour le traitement des maladies degeneratives de la retine et notamment des maladies conditionnees genetiquement, et un procede pour leur obtention |
| JP3041923B2 (ja) * | 1990-06-27 | 2000-05-15 | 藤沢薬品工業株式会社 | ジヒドロピリジン化合物を含有する抗炎症および活性酸素産生抑制剤 |
| US5691360A (en) * | 1993-12-08 | 1997-11-25 | Alcon Laboratories, Inc. | Compounds having both potent calcium antagonist and antioxidant activity and use thereof as cytoprotective agents |
| EP0911027A4 (en) | 1996-04-26 | 2000-11-29 | Fujisawa Pharmaceutical Co | THE DIHYDROPYRIDINE CONTAINS TO IMPROVE THE CIRCULATION OF THE EYE-SURROUNDING TISSUE |
| JPH1072347A (ja) | 1996-05-27 | 1998-03-17 | Otsuka Pharmaceut Co Ltd | 眼血管血流改善剤 |
-
1999
- 1999-09-29 EP EP99970023A patent/EP1117404A1/en not_active Withdrawn
- 1999-09-29 AU AU59983/99A patent/AU5998399A/en not_active Abandoned
- 1999-09-29 WO PCT/JP1999/005321 patent/WO2000020002A1/en not_active Ceased
- 1999-09-29 CA CA002346086A patent/CA2346086A1/en not_active Abandoned
- 1999-09-29 JP JP2000573361A patent/JP2002526409A/ja not_active Withdrawn
- 1999-09-29 BR BR9914254-6A patent/BR9914254A/pt not_active Application Discontinuation
- 1999-09-30 US US09/408,562 patent/US6248759B1/en not_active Expired - Fee Related
- 1999-10-01 AR ARP990104979A patent/AR020681A1/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2000020002A1 (en) | 2000-04-13 |
| JP2002526409A (ja) | 2002-08-20 |
| EP1117404A1 (en) | 2001-07-25 |
| CA2346086A1 (en) | 2000-04-13 |
| AU5998399A (en) | 2000-04-26 |
| AR020681A1 (es) | 2002-05-22 |
| US6248759B1 (en) | 2001-06-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA10 | Dismissal: dismissal - article 33 of industrial property law | ||
| B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |