BR9812635A - Sais ácidos de 1- metil éster n-[n-(3,3-dimetilbutil) -l-alfa-aspartil]-l-fenilalanina - Google Patents

Sais ácidos de 1- metil éster n-[n-(3,3-dimetilbutil) -l-alfa-aspartil]-l-fenilalanina

Info

Publication number
BR9812635A
BR9812635A BR9812635-0A BR9812635A BR9812635A BR 9812635 A BR9812635 A BR 9812635A BR 9812635 A BR9812635 A BR 9812635A BR 9812635 A BR9812635 A BR 9812635A
Authority
BR
Brazil
Prior art keywords
dimethylbutyl
phenylalanine
methyl ester
aspart
acid salts
Prior art date
Application number
BR9812635-0A
Other languages
English (en)
Inventor
Indra Prakash
Kurt L Wachholder
Original Assignee
Nutrasweet Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nutrasweet Co filed Critical Nutrasweet Co
Publication of BR9812635A publication Critical patent/BR9812635A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30—Artificial sweetening agents
    • A23L27/31—Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives
    • A23L27/32—Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives containing dipeptides or derivatives

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Nutrition Science (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Seasonings (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Patente de Invenção: <B>"SAIS áCIDOS DE 1- METIL éSTER DE N-[N-(3,3-DIMETILBUTIL) - L-<244>-ASPARTIL]-L-FENILALANINA"<D>. São descritos adoçantes de dipeptídio que são sais de 1-metil éster de N-[N-(3,3-dimetilbutil)-L-<244>-aspartil]-L-fenilalanina representado pela fórmula (I), na qual X^ -^ é selecionado a partir do grupo que consiste em Cl^ -^, HSO~ 4~^ -^, H~ 2~PO~ 3~^ -^, citrato^ -^, HCO~ 3~^ -^, fumarato, malato, maleiato, tartarato, acetato, benzoato ou gliconato. Também é descrito um adoçante líquido de baixa caloria que contém esses sais.
BR9812635-0A 1997-09-11 1998-09-11 Sais ácidos de 1- metil éster n-[n-(3,3-dimetilbutil) -l-alfa-aspartil]-l-fenilalanina BR9812635A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5850597P 1997-09-11 1997-09-11
PCT/US1998/018902 WO1999012956A1 (en) 1997-09-11 1998-09-11 ACID SALTS OF N-[N-(3,3-DIMETHYLBUTYL)-L-α-ASPARTYL]-L-PHENYLALANINE 1-METHYL ESTER

Publications (1)

Publication Number Publication Date
BR9812635A true BR9812635A (pt) 2000-08-22

Family

ID=22017224

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9812635-0A BR9812635A (pt) 1997-09-11 1998-09-11 Sais ácidos de 1- metil éster n-[n-(3,3-dimetilbutil) -l-alfa-aspartil]-l-fenilalanina

Country Status (18)

Country Link
US (1) US6180156B1 (pt)
EP (1) EP1012168A1 (pt)
CN (1) CN1278827A (pt)
AU (1) AU753013B2 (pt)
BG (1) BG104323A (pt)
BR (1) BR9812635A (pt)
CA (1) CA2303436A1 (pt)
EE (1) EE200000119A (pt)
HU (1) HUP0003573A3 (pt)
ID (1) ID27534A (pt)
IL (1) IL134914A0 (pt)
LT (1) LT4759B (pt)
NO (1) NO20001270L (pt)
PL (1) PL339207A1 (pt)
SI (1) SI20330A (pt)
SK (1) SK3272000A3 (pt)
TR (1) TR200000730T2 (pt)
WO (1) WO1999012956A1 (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6692778B2 (en) * 1998-06-05 2004-02-17 Wm. Wrigley Jr. Company Method of controlling release of N-substituted derivatives of aspartame in chewing gum
AU3914200A (en) * 1999-03-25 2000-10-09 Nutrasweet Company, The Edible gels sweetened with n-(n-(3,3-dimethylbutyl)-l-alpha-aspartyl)-l-phenylalanine 1-methyl ester
WO2000057725A1 (en) * 1999-03-26 2000-10-05 The Nutrasweet Company PARTICLES OF N-[N-(3,3-DIMETHYLBUTYL)-L-α-ASPARTYL]-L-PHENYLALANINE 1-METHYL ESTER
WO2000069282A1 (en) * 1999-05-13 2000-11-23 The Nutrasweet Company Modification of the taste and physicochemical properties of neotame using hydrophobic acid additives
WO2000069283A1 (en) * 1999-05-13 2000-11-23 The Nutrasweet Company USE OF ADDITIVES TO MODIFY THE TASTE CHARACTERISTICS OF N-NEOHEXYL-α-ASPARTYL-L-PHENYLALANINE METHYL ESTER
US7326430B2 (en) * 2000-07-18 2008-02-05 The Nutrasweet Company Method of preparing liquid compositions for delivery of N-[N- (3,3-dimethylbutyl-L-α-aspartyl]-L-phenylalanine 1-methyl ester in food and beverage systems
US20080038411A1 (en) * 2006-06-30 2008-02-14 Michael Jensen Seasoning and method for enhancing and potentiating food flavor
US20110097449A1 (en) * 2006-06-30 2011-04-28 Conagra Foods Rdm, Inc. Seasoning and method for seasoning a food product while reducing dietary sodium intake
US7923047B2 (en) * 2006-06-30 2011-04-12 Conagra Foods Rdm, Inc. Seasoning and method for seasoning a food product while reducing dietary sodium intake
US20080008790A1 (en) * 2006-06-30 2008-01-10 Michael Jensen Seasoned food, seasoning, and method for seasoning a food product
NZ575995A (en) * 2006-09-27 2011-03-31 Conagra Foods Rdm Inc Seasoning and method for enhancing and potentiating food flavor utilizing microencapsulation
CN109180914B (zh) * 2018-04-05 2021-02-02 河南金丹乳酸科技股份有限公司 利用l-乳酸经寡聚、熔融缩聚和固相缩聚生产聚l-乳酸的方法
CN112321676B (zh) * 2020-12-12 2022-06-14 山东诚汇双达药业有限公司 一种纽甜的成盐方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4029701A (en) 1972-03-30 1977-06-14 General Foods Corporation Sweetening with hydrohalide salts of dipeptide sweeteners
US4031258A (en) 1972-03-30 1977-06-21 General Foods Corporation Inorganic salts of dipeptide sweeteners
GB1431057A (en) * 1972-03-30 1976-04-07 Gen Foods Corp Sweetining compositions
CA1028197A (en) 1973-04-02 1978-03-21 Jeffrey H. Berg Concentrated liquid low calorie sweetener
US4448716A (en) 1982-03-04 1984-05-15 G. D. Searle & Co. Dipeptide sweetener-metal complexes
FR2697844B1 (fr) 1992-11-12 1995-01-27 Claude Nofre Nouveaux composés dérivés de dipeptides ou d'analogues dipeptidiques utiles comme agents édulcorants, leur procédé de préparation.
FR2719590B1 (fr) 1994-05-09 1996-07-26 Claude Nofre Procédé perfectionné de préparation d'un composé dérivé de l'aspartame utile comme agent édulcorant.
CA2194065A1 (en) 1994-06-28 1996-01-11 Filippo Mileto A communication system for supplying information on objects on display by means of hand-held devices
US5728862A (en) 1997-01-29 1998-03-17 The Nutrasweet Company Method for preparing and purifying an N-alkylated aspartame derivative

Also Published As

Publication number Publication date
US6180156B1 (en) 2001-01-30
EE200000119A (et) 2000-12-15
EP1012168A1 (en) 2000-06-28
ID27534A (id) 2001-04-12
NO20001270L (no) 2000-05-10
TR200000730T2 (tr) 2001-06-21
PL339207A1 (en) 2000-12-04
SI20330A (sl) 2001-02-28
CN1278827A (zh) 2001-01-03
BG104323A (en) 2001-02-28
LT4759B (lt) 2001-02-26
HUP0003573A2 (hu) 2001-05-28
LT2000026A (en) 2000-09-25
IL134914A0 (en) 2001-05-20
NO20001270D0 (no) 2000-03-10
SK3272000A3 (en) 2000-10-09
WO1999012956A1 (en) 1999-03-18
CA2303436A1 (en) 1999-03-18
AU9384498A (en) 1999-03-29
HUP0003573A3 (en) 2001-08-28
AU753013B2 (en) 2002-10-03

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Legal Events

Date Code Title Description
FA10 Dismissal: dismissal - article 33 of industrial property law
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]
B15K Others concerning applications: alteration of classification

Ipc: C07K 5/072 (2006.01), A23L 27/30 (2016.0