BR9810790A - Indole and 2, 3 dihydroindole derivatives, preparation and use thereof - Google Patents

Indole and 2, 3 dihydroindole derivatives, preparation and use thereof

Info

Publication number
BR9810790A
BR9810790A BR9810790-9A BR9810790A BR9810790A BR 9810790 A BR9810790 A BR 9810790A BR 9810790 A BR9810790 A BR 9810790A BR 9810790 A BR9810790 A BR 9810790A
Authority
BR
Brazil
Prior art keywords
indole
preparation
derivatives
dihydroindole derivatives
dihydroindole
Prior art date
Application number
BR9810790-9A
Other languages
Portuguese (pt)
Inventor
Ejner Knud Moltzen
Jeans Kristian Perregaard
Ivan Mikkelsen
Garrick Paul Smith
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Priority claimed from PCT/DK1998/000336 external-priority patent/WO1999005140A1/en
Publication of BR9810790A publication Critical patent/BR9810790A/en

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)

Abstract

<B>"INDOL E DERIVADOS DE 2,3 DIIDROINDOL, PREPARAçAO E UTILIZAçãO DOS MESMOS"<D> A presente invenção refere-se a indol e derivados de 2,3-diidroindol possuindo a fórmula (I), qualquer de seus enantiómeros ou qualquer mistura dos mesmos, ou um sal de adição de ácido dos mesmos, onde A, R^ 1^, R^ 2^, R^ 3^, W, X, Y são como o descrito na descrição. Os compostos são potentes inibidores de recaptação de serotonina e possuem atividade antagonista de receptor 5-HT~ 1A~.<B> "INDOL AND 2,3-DIIDROINDOL DERIVATIVES, PREPARATION AND USE OF THE SAME" <D> The present invention relates to indole and 2,3-dihydroindole derivatives having the formula (I), any of its enantiomers or any mixture thereof, or an acid addition salt thereof, where A, R ^ 1 ^, R ^ 2 ^, R ^ 3 ^, W, X, Y are as described in the description. The compounds are potent serotonin reuptake inhibitors and have 5-HT ~ 1A ~ receptor antagonistic activity.

BR9810790-9A 1997-07-25 1998-07-20 Indole and 2, 3 dihydroindole derivatives, preparation and use thereof BR9810790A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK89297 1997-07-25
PCT/DK1998/000336 WO1999005140A1 (en) 1997-07-25 1998-07-20 Indole and 2,3-dihydroindole derivatives, their preparation and use

Publications (1)

Publication Number Publication Date
BR9810790A true BR9810790A (en) 2000-07-25

Family

ID=8098721

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9810790-9A BR9810790A (en) 1997-07-25 1998-07-20 Indole and 2, 3 dihydroindole derivatives, preparation and use thereof

Country Status (13)

Country Link
CN (3) CN1286833C (en)
AR (1) AR013206A1 (en)
BR (1) BR9810790A (en)
EA (1) EA001890B1 (en)
HK (3) HK1030220A1 (en)
IL (1) IL133990A (en)
IS (1) IS2024B (en)
NO (1) NO318610B1 (en)
PL (1) PL190924B1 (en)
SK (1) SK284866B6 (en)
TR (1) TR200000231T2 (en)
UA (1) UA59408C2 (en)
ZA (1) ZA986237B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103420989B (en) * 2012-05-15 2016-03-23 华中科技大学 Benzodioxane derivative and application thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8830312D0 (en) * 1988-12-28 1989-02-22 Lundbeck & Co As H Heterocyclic compounds
DE4127849A1 (en) * 1991-08-22 1993-02-25 Merck Patent Gmbh BENZODIOXAN DERIVATIVES
FR2692264B1 (en) * 1992-06-12 1994-08-05 Adir NOVEL 1,4-DISUBSTITUTED PIPERAZINES, THEIR PREPARATION PROCESS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.

Also Published As

Publication number Publication date
UA59408C2 (en) 2003-09-15
NO20000372D0 (en) 2000-01-25
CN1515569A (en) 2004-07-28
CN1293075C (en) 2007-01-03
HK1066807A1 (en) 2005-04-01
AR013206A1 (en) 2000-12-13
IS5334A (en) 2000-01-11
IL133990A0 (en) 2001-04-30
CN1265107A (en) 2000-08-30
TR200000231T2 (en) 2000-07-21
EA200000162A1 (en) 2000-10-30
HK1066806A1 (en) 2005-04-01
CN1286833C (en) 2006-11-29
IS2024B (en) 2005-08-15
PL190924B1 (en) 2006-02-28
HK1030220A1 (en) 2001-04-27
CN1127501C (en) 2003-11-12
SK952000A3 (en) 2001-03-12
SK284866B6 (en) 2006-01-05
IL133990A (en) 2003-09-17
EA001890B1 (en) 2001-10-22
PL338194A1 (en) 2000-10-09
NO318610B1 (en) 2005-04-18
NO20000372L (en) 2000-03-21
ZA986237B (en) 1999-03-31
CN1515568A (en) 2004-07-28

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Legal Events

Date Code Title Description
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B11B Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements