BR9809364A - Metabolismo de regulação por modificação do nìvel de trehalose-6-fosfato por inibição dos nìveis de trehalase endógena - Google Patents

Metabolismo de regulação por modificação do nìvel de trehalose-6-fosfato por inibição dos nìveis de trehalase endógena

Info

Publication number
BR9809364A
BR9809364A BR9809364-9A BR9809364A BR9809364A BR 9809364 A BR9809364 A BR 9809364A BR 9809364 A BR9809364 A BR 9809364A BR 9809364 A BR9809364 A BR 9809364A
Authority
BR
Brazil
Prior art keywords
trehalose
phosphate
level
modifying
regulation
Prior art date
Application number
BR9809364-9A
Other languages
English (en)
Inventor
Oscar Johnnes Maria Goddijn
Jan Pen
Josephus Christianus Smeekens
Maria Theresia Smits
Original Assignee
Mogen Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/EP1997/002497 external-priority patent/WO1997042326A2/en
Application filed by Mogen Int filed Critical Mogen Int
Publication of BR9809364A publication Critical patent/BR9809364A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8245—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified carbohydrate or sugar alcohol metabolism, e.g. starch biosynthesis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01028—Alpha,alpha-trehalase (3.2.1.28)
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
    • Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
    • Y02A40/146—Genetically Modified [GMO] plants, e.g. transgenic plants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Nutrition Science (AREA)
  • Medicinal Chemistry (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

"METABOLISMO DE REGULAçãO POR MODIFICAçãO DO NìVEL DE TREHALOSE-6-FOSFATO POR INIBIçãO DOS NìVEIS DE TREHALASE ENDóGENA" A invenção encontra-se no campo de regulação do fluxo de carbono no metabolismo da célula. Foi verificado que a indução de uma alteração na disponibilidade intracelular do sacarídeo trehalose-6-fosfato (T-6-P) induz modificações do desenvolvimento e/ou composição das células, tecido e órgãos in vivo. Estas alterações podem ser induzidas por inibição da enzima endógena trehalase que é capaz de hidrolisar trehalose em duas porções de glicose.
BR9809364-9A 1997-05-02 1998-05-04 Metabolismo de regulação por modificação do nìvel de trehalose-6-fosfato por inibição dos nìveis de trehalase endógena BR9809364A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/EP1997/002497 WO1997042326A2 (en) 1996-05-03 1997-05-02 Regulating metabolism by modifying the level of trehalose-6-phosphate
PCT/EP1998/002788 WO1998050561A1 (en) 1997-05-02 1998-05-04 Regulating metabolism by modifying the level of trehalose-6-phosphate by inhibiting endogenous trehalase levels

Publications (1)

Publication Number Publication Date
BR9809364A true BR9809364A (pt) 2001-09-11

Family

ID=8166628

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9809364-9A BR9809364A (pt) 1997-05-02 1998-05-04 Metabolismo de regulação por modificação do nìvel de trehalose-6-fosfato por inibição dos nìveis de trehalase endógena

Country Status (11)

Country Link
US (1) US20030177531A1 (pt)
EP (1) EP0977870A1 (pt)
JP (1) JP2001523110A (pt)
KR (1) KR20010012147A (pt)
CN (1) CN1260001A (pt)
AU (1) AU738098B2 (pt)
BR (1) BR9809364A (pt)
CA (1) CA2288672A1 (pt)
HU (1) HUP0002948A3 (pt)
IL (1) IL132498A0 (pt)
WO (1) WO1998050561A1 (pt)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8022272B2 (en) 2001-07-13 2011-09-20 Sungene Gmbh & Co. Kgaa Expression cassettes for transgenic expression of nucleic acids
EP1375669A1 (en) * 2002-06-13 2004-01-02 Stichting Voor De Technische Wetenschappen Method for enhancing the disease resistance in plants by altering trehalose-6-phosphate levels
US8129588B2 (en) * 2004-04-20 2012-03-06 Syngenta Participations Ag Regulatory sequences for expressing gene products in plant reproductive tissue
EP1645633B1 (en) 2004-10-05 2011-09-21 SunGene GmbH Constitutive expression cassettes for regulation of plant expression
EP1655364A3 (en) 2004-11-05 2006-08-02 BASF Plant Science GmbH Expression cassettes for seed-preferential expression in plants
EP1662000B1 (en) 2004-11-25 2011-03-30 SunGene GmbH Expression cassettes for guard cell-preferential expression in plants
EP1666599A3 (en) 2004-12-04 2006-07-12 SunGene GmbH Expression cassettes for mesophyll- and/or epidermis-preferential expression in plants
EP2163634A1 (en) 2004-12-08 2010-03-17 SunGene GmbH Expression cassettes for vascular tissue-preferential expression in plants
EP1669456A3 (en) 2004-12-11 2006-07-12 SunGene GmbH Expression cassettes for meristem-preferential expression in plants
CN101155922A (zh) 2005-02-09 2008-04-02 巴斯福植物科学有限公司 在单子叶植物中调控表达的表达盒
CA2598307C (en) 2005-02-26 2014-12-30 Basf Plant Science Gmbh Expression cassettes for seed-preferential expression in plants
WO2006094976A2 (en) 2005-03-08 2006-09-14 Basf Plant Science Gmbh Expression enhancing intron sequences
EP1874936B1 (en) 2005-04-19 2013-10-30 BASF Plant Science GmbH Improved methods controlling gene expression
US7790873B2 (en) 2005-05-10 2010-09-07 Basf Plant Science Gmbh Expression cassettes for seed-preferential expression in plants
EP2436769B1 (en) 2006-06-07 2015-04-01 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Plant expression constructs and methods of utilizing same
EP2074219B1 (en) 2007-02-16 2013-11-20 BASF Plant Science GmbH Nucleic acid sequences for regulation of embryo-specific expression in monocotyledonous plants
RU2012103038A (ru) 2009-06-30 2013-08-10 Йассум Ресерч Девелопмент Кампани Оф Зе Хибрю Юниверсити Оф Иерусалим Лтд. Введение днк в растительные клетки
WO2011003901A1 (en) 2009-07-10 2011-01-13 Basf Plant Science Company Gmbh Expression cassettes for endosperm-specific expression in plants
BR112012013156A2 (pt) 2009-12-03 2017-06-13 Basf Plant Science Co Gmbh cassete de expressão, vetor, célula horpedeira, tecido de planta transgênica e método para a produção de um tecido de planta transgênica
AU2012308581A1 (en) * 2011-09-13 2014-05-01 Stoller Enterprises, Inc. Method for enhancing crop yields by application of trehalose
US20150040268A1 (en) 2013-04-25 2015-02-05 Morflora Israel Ltd Methods and compositions for the delivery of nucleic acids to seeds
CN110257407B (zh) * 2019-07-08 2023-04-28 东北林业大学 一种海藻糖酶基因Bx-tre1及其应用
CN110801048B (zh) * 2019-12-02 2021-09-28 中国烟草总公司郑州烟草研究院 海藻糖在烟叶烘烤过程中作为淀粉代谢过程中信号分子的应用
CN111990259B (zh) * 2020-09-11 2021-11-30 上海辰山植物园 香石竹高保真种苗繁育方法
CN114868760B (zh) * 2022-05-13 2024-01-16 辽宁省农业科学院 6-磷酸-海藻糖的应用及提升普通菜豆产量和抗病性的培育方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8811115D0 (en) * 1988-05-11 1988-06-15 Ici Plc Tomatoes
ATE133198T1 (de) * 1990-03-28 1996-02-15 Gist Brocades Nv Neue hefestämme mit erhöhtem trehalosegehalt, verfahren zur gewinnung solcher hefen und verwendung dieser hefen
FI943133A0 (fi) * 1994-06-29 1994-06-29 Alko Ab Oy Transgena vaexter
DE4444460A1 (de) * 1994-11-29 1996-05-30 Inst Genbiologische Forschung Verfahren zur Steigerung des Ertrags sowie zur Veränderung des Blühverhaltens bei Pflanzen
IL116564A0 (en) * 1995-01-04 1996-03-31 Mogen Int Process for producing trehalose in plants
US5587290A (en) * 1995-06-26 1996-12-24 The Regents Of The University Of California Stress tolerant yeast mutants
EP0784095A3 (en) * 1996-01-12 1997-12-29 Mogen International N.V. Enhanced accummulation of trehalose in plants
IN1997CH00924A (en) * 1996-05-03 2005-03-04 Syngenta Mogen Bv Regulating metabolism by modifying the level of trehalose-6-phosphate

Also Published As

Publication number Publication date
AU738098B2 (en) 2001-09-06
AU7764498A (en) 1998-11-27
JP2001523110A (ja) 2001-11-20
HUP0002948A2 (hu) 2001-02-28
US20030177531A1 (en) 2003-09-18
CN1260001A (zh) 2000-07-12
HUP0002948A3 (en) 2002-09-30
KR20010012147A (ko) 2001-02-15
WO1998050561A1 (en) 1998-11-12
IL132498A0 (en) 2001-03-19
CA2288672A1 (en) 1998-11-12
EP0977870A1 (en) 2000-02-09

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Legal Events

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B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A, 8A E 9A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1889 DE 20/03/2007.