BR9809326A - Novos conjugados hetero-polissacarìdeos, novos géis s-inp polissacarìdeos e seus métodos de fabricação e utilização - Google Patents

Novos conjugados hetero-polissacarìdeos, novos géis s-inp polissacarìdeos e seus métodos de fabricação e utilização

Info

Publication number
BR9809326A
BR9809326A BR9809326-6A BR9809326A BR9809326A BR 9809326 A BR9809326 A BR 9809326A BR 9809326 A BR9809326 A BR 9809326A BR 9809326 A BR9809326 A BR 9809326A
Authority
BR
Brazil
Prior art keywords
alginate
gels
glycosaminoglycan
new
cross
Prior art date
Application number
BR9809326-6A
Other languages
English (en)
Inventor
Marcos Mares-Guia
Camillo Ricordi
Original Assignee
Biomm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomm Inc filed Critical Biomm Inc
Publication of BR9809326A publication Critical patent/BR9809326A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
    • A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L17/00—Materials for surgical sutures or for ligaturing blood vessels ; Materials for prostheses or catheters
    • A61L17/14—Post-treatment to improve physical properties
    • A61L17/145—Coating
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0084—Guluromannuronans, e.g. alginic acid, i.e. D-mannuronic acid and D-guluronic acid units linked with alternating alpha- and beta-1,4-glycosidic bonds; Derivatives thereof, e.g. alginates
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/04—Alginic acid; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Materials Engineering (AREA)
  • Zoology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Vascular Medicine (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Botany (AREA)
  • Dermatology (AREA)
  • Surgery (AREA)
  • Transplantation (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Colloid Chemistry (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)

Abstract

"NOVOS CONJUGADOS HETERO-POLISSACARìDEOS, NOVOS GéIS s-INP POLISSACARìDEOS E SEUS MéTODOS DE FABRICAçãO E UTILIZAçãO" O revelado e reivindicado são: uma composição que inclui pelo menos um glicosaminoglican, por ex., CIS, e pelo menos um alginato, por ex., alginato de sódio, onde: pelo menos um glicosaminoglican e/ou o alginato são reticulados ou polimerizados, por ex., o alginato é reticulado ou polimerizado, por exemplo por meio da adição de um sal inorgânico, tal como um sal de cálcio; ou o pelo menos um glicosaminoglican e o alginato são covalentemente ligados, por ex., por meio de uma reação de união que envolve uma molécula ligante tal como DVS; ou o pelo menos um glicosaminoglican e/ou o alginato são reticulados ou polimerizados, por ex., o alginato é reticulado ou polimerizado, por exemplo por meio da adição de um sal inorgânico, tal como um sal de cálcio, e o pelo menos um glicosaminoglican e o alginato são covalentemente ligados, por ex., por meio de uma reação de união que envolve uma molécula ligante tal como DVS, e a ligação covalente pode ter sido executada antes da reticulação ou polimerização ou vice versa; e, os géis que compreendem a composição; a mistura dos tais géis ou de pelo menos um gel específico e pelo menos uma composição específica; e, os métodos para fabricar e utilizar tais composições e géis que incluem produtos deles derivados tais como "pinturas", aspersões, matrizes, pérolas, microcápsulas.
BR9809326-6A 1997-04-30 1998-04-30 Novos conjugados hetero-polissacarìdeos, novos géis s-inp polissacarìdeos e seus métodos de fabricação e utilização BR9809326A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4511197P 1997-04-30 1997-04-30
US08/877,682 US6281341B1 (en) 1997-04-30 1997-06-17 Hetero-polysaccharide conjugate and methods of making and using the same
PCT/US1998/008752 WO1998049202A1 (en) 1997-04-30 1998-04-30 NOVEL HETERO-POLYSACCHARIDE CONJUGATES, NOVEL s-INP POLYSACCHARIDE GELS AND METHODS OF MAKING AND USING THE SAME

Publications (1)

Publication Number Publication Date
BR9809326A true BR9809326A (pt) 2000-07-04

Family

ID=26722388

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9809326-6A BR9809326A (pt) 1997-04-30 1998-04-30 Novos conjugados hetero-polissacarìdeos, novos géis s-inp polissacarìdeos e seus métodos de fabricação e utilização

Country Status (6)

Country Link
US (1) US6281341B1 (pt)
EP (1) EP0977780B1 (pt)
AT (1) ATE275585T1 (pt)
BR (1) BR9809326A (pt)
DE (1) DE69826119T2 (pt)
WO (1) WO1998049202A1 (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE321562T1 (de) * 1999-01-04 2006-04-15 Biomm Inc Neue polymer zubereitungen enthaltende perluorierte verbindungen zur technischen handhabung von zellen und gewebe bei transplantationen, um den metabolismus und die überlebensrate der zellen zu verbessern, sowie verfahren zu deren herstellung
CA2597757C (en) 2005-02-10 2016-06-28 Regents Of The University Of Minnesota Vascular/lymphatic endothelial cells
FR2925316B1 (fr) * 2007-12-21 2010-02-12 Oreal Kit comprenant un alginate et un agent de complexation sous forme de sel insoluble dans l'eau
FR2925310B1 (fr) * 2007-12-21 2010-03-05 Oreal Kit de mascara comprenant un alginate et un agent de complexation
FR2925306B1 (fr) * 2007-12-21 2010-03-05 Oreal Kit pour la peau et les levres comprenant un alginate et un agent de complexation
FR2925315B1 (fr) * 2007-12-21 2010-02-12 Oreal Kit comprenant un alginate et un agent de complexation sous forme de sel hydrosoluble
EP2196196A1 (en) * 2008-12-10 2010-06-16 Medipol S.A. Compound, medicament, vaccine composition and nanocapsules
CN101570582B (zh) * 2009-05-26 2011-07-20 中山大学附属第一医院 一种具有水溶性和生物降解性的电活性聚合物及其制备方法和应用
WO2011160066A1 (en) 2010-06-17 2011-12-22 Regents Of The University Of Minnesota Production of insulin producing cells
JP6042815B2 (ja) 2010-10-08 2016-12-14 ザ ボード オブ リージェンツ オブ ザ ユニバーシティ オブ テキサス システム 生物医学的応用のためのアルギン酸塩及びヒアルロン酸を用いる抗癒着性バリア膜
WO2012048283A1 (en) 2010-10-08 2012-04-12 Board Of Regents, The University Of Texas System One-step processing of hydrogels for mechanically robust and chemically desired features
KR20140059238A (ko) * 2011-11-11 2014-05-15 미바 메디컬 아이엔시. 주사 시술용 보형물
EP2892541B1 (en) 2012-09-04 2021-04-21 Technion Research & Development Foundation Limited Use of decellularized extracellular matrix for encapsulating cells
FI129934B (en) 2015-02-13 2022-11-15 Upm Kymmene Corp Sewing thread, method of making sewing thread and its use
EP3512561A4 (en) * 2016-09-16 2020-10-07 Glycologix, LLC SULFATED GLYCOSAMINOGLYCAN BIOMATERIALS AS PROTEOGLYCAN MIMETICS
WO2018165327A1 (en) 2017-03-08 2018-09-13 Alafair Biosciences, Inc. Hydrogel medium for the storage and preservation of tissue
WO2022145419A1 (ja) 2020-12-28 2022-07-07 持田製薬株式会社 化学架橋アルギン酸を用いた多層構造体

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4409331A (en) * 1979-03-28 1983-10-11 Damon Corporation Preparation of substances with encapsulated cells
US5129877A (en) * 1988-04-29 1992-07-14 University Of Georgia Research Foundation, Inc. Receptor-mediated delivery system
FR2636339B1 (fr) * 1988-09-09 1992-07-17 Auge Pier Gel aqueux a base d'acide hyaluronique et d'acide desoxyribonucleique utilisable en cosmetique, et procede de preparation
FR2652741B1 (fr) * 1989-10-10 1994-03-04 Laboratoires Care System Composition antimicrobienne pour application sur la peau, applications comme deodorant corporel et bactericide cutane.
US5084350A (en) * 1990-02-16 1992-01-28 The Royal Institution For The Advance Of Learning (Mcgill University) Method for encapsulating biologically active material including cells
IT1248666B (it) * 1990-05-30 1995-01-26 Fidia Spa Gel in forma di film autosupportanti altamente idrati, processo per laloro preparazione e impiego nella terapia di lesioni e/o patologie cutanee
GB9320232D0 (en) 1993-10-01 1993-11-17 C V Lab Ltd Alginate wound dressing

Also Published As

Publication number Publication date
DE69826119D1 (de) 2004-10-14
WO1998049202A1 (en) 1998-11-05
ATE275585T1 (de) 2004-09-15
EP0977780B1 (en) 2004-09-08
EP0977780A1 (en) 2000-02-09
US6281341B1 (en) 2001-08-28
DE69826119T2 (de) 2005-09-15
EP0977780A4 (en) 2002-02-27

Similar Documents

Publication Publication Date Title
BR0007296A (pt) Novas formulações poliméricas contendo compostos perfluorados para a engenharia de células e tecidos para transplantes que melhoram o metabolismo e a sobrevivência celular, e métodos para a sua produção
BR9809326A (pt) Novos conjugados hetero-polissacarìdeos, novos géis s-inp polissacarìdeos e seus métodos de fabricação e utilização
WO2003084982A3 (en) Functionalized compositions for improved immobilization
AU9677698A (en) Method for the covalent attachment of polysaccharides to protein molecules
AU6973498A (en) Sustained-release alginate gels
GB2314840B (en) Oxidized oligosaccharides and pharmaceutical compositions
AU3499395A (en) Ionene polymers containing biologically-active anions
NO20002547L (no) Poly(vinylamin)-baserte superabsorberende geler og fremgangsmÕte for fremstilling derav
RU2218349C2 (ru) Агрегаты производных инсулина человека
CA2266581A1 (en) Polymers containing polysaccharides such as alginates or modified alginates
ES2121379T3 (es) Preparacion de composiciones de asfalto/polimero, y su utilizacion.
EP0401044A3 (en) Absorbent polymers and their production
AU7068196A (en) Use of an aqueous polymer dispersion to produce water-vapor barriers
MX9802675A (es) Polimeros de etileno de bloque ramificados, su preparacion y composiciones que los comprenden.
AU3076601A (en) Chemically-programmable immunity
EP1220606A4 (en) METHODS OF PRODUCING A TARGET MOLECULE IN A TRANSGENIC ANIMAL AND OF PURIFYING THE TARGET MOLECULE
GB9506806D0 (en) Improvements relating to polymers
ATE231411T1 (de) Verwendung eines adsorbierenden gels zur entfernung und reinigung von biomolekülen
PL328720A1 (en) Covalent modification of surfaces by use of polymers in order to improve biological compatibility
WO1998052620A3 (en) Collagen-like polymers with cell binding activity
McCourt et al. On the adsorption of hyaluronan and ICAM-1 to modified hydrophobic resins
ES2177802T3 (es) Procedimiento para la fabricacion de aerogeles organofuncionalizados.
NO20010286D0 (no) Anvendelse av modifiserte stivelsesprodukter som retensjonsmidler ved fremstilling av papir
DE60219013D1 (de) Kupplung von cyclooligosacchariden zu polysacchariden
EP0755939A3 (de) Verfahren zur gezielten Synthese von Beta-glycosidisch verknüpften N-Acetylglucosaminderivaten

Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PRESENTE PEDIDO DE PATENTE COMO INVENCAO - DE ACORDO COM O ART. 8O DA LPI.