BR9808494A - Composições sólidas adequadas para administração oral as quais compreendem um citrato de alcanoil-l-carnitina magnésio - Google Patents

Composições sólidas adequadas para administração oral as quais compreendem um citrato de alcanoil-l-carnitina magnésio

Info

Publication number
BR9808494A
BR9808494A BR9808494-1A BR9808494A BR9808494A BR 9808494 A BR9808494 A BR 9808494A BR 9808494 A BR9808494 A BR 9808494A BR 9808494 A BR9808494 A BR 9808494A
Authority
BR
Brazil
Prior art keywords
alkanoyl
magnesium
oral administration
compositions suitable
solid compositions
Prior art date
Application number
BR9808494-1A
Other languages
English (en)
Other versions
BR9808494B1 (pt
Inventor
Nazareno Scafetta
Maria Ornella Tinti
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Publication of BR9808494A publication Critical patent/BR9808494A/pt
Publication of BR9808494B1 publication Critical patent/BR9808494B1/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/235—Saturated compounds containing more than one carboxyl group
    • C07C59/245—Saturated compounds containing more than one carboxyl group containing hydroxy or O-metal groups
    • C07C59/265—Citric acid
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/105—Aliphatic or alicyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms

Abstract

Patente de Invenção: <B>"COMPOSIçõES SóLIDAS ADEQUADAS PARA ADMINISTRAçãO ORAL AS QUAIS COMPREENDEM UM CITRATO DE ALCANOIL-L-CARNITINA MAGNéSIO"<D>. A presente invenção apresenta sais estáveis e não-higroscópicos que consistem em citratos de alcanoil-L-carnitina magnésio inferiores que são adequados para preparação de composições sólidas úteis como suplementos dietéticos/nutricionais para uso humano e como suplemento de forragem para fins veterinários.
BRPI9808494-1A 1997-04-08 1998-03-19 sal de alcanoil-l-carnitina e composição compreendendo o mesmo. BR9808494B1 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT97RM000198A IT1291134B1 (it) 1997-04-08 1997-04-08 Composizioni solide atte alla somministrazione orale comprendenti una alcanoil l-carnitina magnesio citrato
PCT/IT1998/000058 WO1998044918A1 (en) 1997-04-08 1998-03-19 Solid compositions suitable for oral administration comprising an alkanoyl-l-carnitine magnesium citrate

Publications (2)

Publication Number Publication Date
BR9808494A true BR9808494A (pt) 2000-05-23
BR9808494B1 BR9808494B1 (pt) 2009-05-05

Family

ID=11404949

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI9808494-1A BR9808494B1 (pt) 1997-04-08 1998-03-19 sal de alcanoil-l-carnitina e composição compreendendo o mesmo.

Country Status (15)

Country Link
US (1) US6337349B2 (pt)
EP (1) EP0973515B1 (pt)
JP (1) JP4047936B2 (pt)
KR (1) KR100517680B1 (pt)
AT (1) ATE230595T1 (pt)
AU (1) AU739522B2 (pt)
BR (1) BR9808494B1 (pt)
CA (1) CA2285552C (pt)
DE (1) DE69810601T2 (pt)
DK (1) DK0973515T3 (pt)
ES (1) ES2190069T3 (pt)
HK (1) HK1025242A1 (pt)
IT (1) IT1291134B1 (pt)
NZ (1) NZ500532A (pt)
WO (1) WO1998044918A1 (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1326502E (pt) * 2000-08-29 2005-09-30 Lonza Ag Processo para a producao de uma mistura apta a ser granulada e hidroxicitrato de carnitina e magnesio
ITRM20020055A1 (it) * 2002-02-04 2003-08-04 Aldo Fassi Sali metallici di carnitine, integratori dietetici/nutritivi che li contengono e kit dietetici per contrastare disturbi sessuali in soggetti
US20050232911A1 (en) * 2004-04-19 2005-10-20 Schreiber Brian D Prevention and treatment of metabolic abnormalities associated with excess intramyocellular lipid
WO2007043339A1 (en) * 2005-09-30 2007-04-19 Showa Denko K.K. Carnitine derivative, salt thereof, external skin preparation and cosmetic material
CN101209975B (zh) 2006-12-29 2010-12-01 沈阳科硕营养科技有限公司 左旋肉碱富马酸钙及其制备方法与用途
US10426750B1 (en) * 2007-09-18 2019-10-01 Thermolife International, Llc Amino acid supplement formulations
US10435356B1 (en) * 2007-09-18 2019-10-08 Thermolife International, Llc Amino acid compositions
US10426792B1 (en) * 2007-09-18 2019-10-01 Thermolife International, Llc Amino acid compositions
US8466187B2 (en) 2007-09-18 2013-06-18 Thermolife International, Llc Amino acid compositions
US10646508B1 (en) 2007-09-18 2020-05-12 Thermolife International, Llc Method of safely administering nitrate dietary supplements and compositions
JP2011524415A (ja) * 2008-06-16 2011-09-01 サイアン ラボラトリーズ，エルエルシー Ｌ−カルニチンフィチン酸塩及びアルカノイル−ｌ−カルニチンフィチン酸塩と、その製造方法
CA2833159C (en) 2011-04-13 2019-08-06 Thermolife International, Llc N-acetyl beta alanine methods of use
CN105777534B (zh) * 2014-12-24 2018-07-06 辽宁科硕营养科技有限公司 柠檬酸钙盐及其制备方法与用途
US11865139B2 (en) 2020-11-12 2024-01-09 Thermolife International, Llc Method of treating migraines and headaches

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1153640A (en) 1967-04-10 1969-05-29 Soc D Etudes Prod Chimique A Carnitin Salt
FR2529545B1 (fr) 1982-07-02 1985-05-31 Sanofi Sa Nouveaux sels de carnitine ainsi que leur procede de preparation
EP0150688B1 (en) * 1983-12-28 1987-04-22 Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. Salts of l-carnitine and alkanoyl l-carnitines and process for preparing same
CA2018137C (en) 1989-06-14 2000-01-11 Thomas Scholl L-carnitine magnesium citrate
US5073376A (en) 1989-12-22 1991-12-17 Lonza Ltd. Preparations containing l-carnitine
IT1261688B (it) * 1993-05-28 1996-05-29 Avantgarde Spa Uso di esteri sull'ossidrile della l-carnitina per produrre composizioni farmaceutiche per il trattamento di affezioni cutanee.
EP0681839A3 (en) * 1994-05-12 1997-11-12 Hirohiko Kuratsune A pharmaceutical preparation comprising an acylcarnitine

Also Published As

Publication number Publication date
US20010027214A1 (en) 2001-10-04
ES2190069T3 (es) 2003-07-16
DK0973515T3 (da) 2003-05-05
BR9808494B1 (pt) 2009-05-05
CA2285552A1 (en) 1998-10-15
NZ500532A (en) 2001-03-30
WO1998044918A1 (en) 1998-10-15
AU739522B2 (en) 2001-10-11
EP0973515A1 (en) 2000-01-26
DE69810601D1 (de) 2003-02-13
AU6745398A (en) 1998-10-30
ATE230595T1 (de) 2003-01-15
US6337349B2 (en) 2002-01-08
HK1025242A1 (en) 2000-11-10
KR100517680B1 (ko) 2005-09-29
CA2285552C (en) 2008-06-03
KR20010005864A (ko) 2001-01-15
JP2001519804A (ja) 2001-10-23
EP0973515B1 (en) 2003-01-08
IT1291134B1 (it) 1998-12-29
DE69810601T2 (de) 2003-08-07
JP4047936B2 (ja) 2008-02-13
ITRM970198A1 (it) 1998-10-08

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Publication Publication Date Title
BR9808494A (pt) Composições sólidas adequadas para administração oral as quais compreendem um citrato de alcanoil-l-carnitina magnésio
CA2288287A1 (en) Solid compositions suitable for oral administration comprising l-carnitine or alkanoyl-l-carnitine magnesium fumarate
CA2285550A1 (en) Solid compositions suitable for oral administration comprising l-carnitine and alkanoyl-l-carnitine magnesium tartrate
CA2286631A1 (en) Solid compositions suitable for oral administration comprising l-carnitine or an alkanoyl-l-carnitinecholine tartrate
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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 19/05/2009, OBSERVADAS AS CONDICOES LEGAIS.

B24H Lapse because of non-payment of annual fees (definitively: art 78 iv lpi)
B24F Patent annual fee: publication cancelled

Free format text: ANULADA A PUBLICACAO CODIGO 24.8 NA RPI NO 2259 DE 22/04/2014 POR TER SIDO INDEVIDA.

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE AS 14A, 15A, 16A, 17A, 18A, 19A, 20A, 21A E 22A ANUIDADES.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2607 DE 22-12-2020 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.