BR9808054A - Método de tratamento e/ou prevenção de diabete melito não-dependente de insulina e composição - Google Patents
Método de tratamento e/ou prevenção de diabete melito não-dependente de insulina e composiçãoInfo
- Publication number
- BR9808054A BR9808054A BR9808054-7A BR9808054A BR9808054A BR 9808054 A BR9808054 A BR 9808054A BR 9808054 A BR9808054 A BR 9808054A BR 9808054 A BR9808054 A BR 9808054A
- Authority
- BR
- Brazil
- Prior art keywords
- insulin
- prevention
- treatment
- dependent diabetes
- composition
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Emergency Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Physical Vapour Deposition (AREA)
Abstract
<B>"MéTODO DE TRATAMENTO E/OU PREVENçãO DE DIABETE MELITO NãO-DEPENDENTE DE INSULINA E COMPOSIçãO"<D> A presente invenção refere-se a métodos para o tratamento e/ou prevenção de diabete melito não dependente de insulina (NIDDM) em sujeitos que tenham desenvolvido ou estejam em risco substancial de desenvolvimento de NIDDM, através da utilização de compostos retinóides específicos que são estruturalmente relacionados com ácido 9-cis retinóide, que induz a diferenciação de pré-adipócitos em adipócitos. Tais compostos podem ser administrados isoladamente ou em combinação com outros agentes anti-diabetogênicos, tais como tiazolidinadionas.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US3560497P | 1997-03-24 | 1997-03-24 | |
PCT/US1998/005591 WO1998042340A1 (en) | 1997-03-24 | 1998-03-24 | Retinoid related molecules for the treatment of non-insulin dependent diabetes mellitus |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9808054A true BR9808054A (pt) | 2000-11-07 |
Family
ID=21883695
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9808054-7A BR9808054A (pt) | 1997-03-24 | 1998-03-24 | Método de tratamento e/ou prevenção de diabete melito não-dependente de insulina e composição |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP1019049A1 (pt) |
JP (1) | JP2001521551A (pt) |
KR (1) | KR20010005678A (pt) |
CN (1) | CN1256630A (pt) |
AU (1) | AU6576398A (pt) |
BR (1) | BR9808054A (pt) |
CA (1) | CA2284192A1 (pt) |
IL (1) | IL132032A0 (pt) |
NO (1) | NO994612L (pt) |
NZ (1) | NZ337927A (pt) |
WO (1) | WO1998042340A1 (pt) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR9915285A (pt) * | 1998-11-12 | 2001-08-07 | Smithkline Beecham Plc | Composição farmacêutica para liberação modificada de um sensitivador de insulina e um outro agente antidiabético |
AR023699A1 (es) * | 1998-11-12 | 2002-09-04 | Smithkline Beecham Corp | Una composicion farmaceutica que comprende un estabilizador de insulina y un procedimiento para preparar una composicion farmaceutica |
US20020198203A1 (en) * | 2001-06-07 | 2002-12-26 | Wyeth | Combination of a PTPase inhibitor and a thiazolidinedione agent |
CN1921843A (zh) * | 2004-01-23 | 2007-02-28 | 独立行政法人科学技术振兴机构 | 含视黄酸的糖尿病治疗药 |
WO2015109231A1 (en) * | 2014-01-17 | 2015-07-23 | Cornell University | Methods of treating metabolic syndrome related conditions using retinoic acid receptor agonists |
US11191755B2 (en) | 2014-01-17 | 2021-12-07 | Cornell University | Compositions and methods for providing cardioprotective effects |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU647735B2 (en) * | 1989-03-08 | 1994-03-31 | University Of Virginia Alumni Patents Foundation, The | Dietary supplement for insulin-resistant diabetics |
FR2695317B1 (fr) * | 1992-09-07 | 1995-03-10 | Monal Lab | Composition apte à stimuler la sécrétion d'insuline destinée au traitement du diabète non insulino-dépendant. |
AU676227B2 (en) * | 1993-01-22 | 1997-03-06 | Kanegafuchi Kagaku Kogyo Kabushiki Kaisha | Therapeutic agent for NIDDM |
US5457109A (en) * | 1993-09-15 | 1995-10-10 | Warner-Lambert Company | Use of thiazolidinedione derivatives and related antihyperglycemic agents in the treatment of disease states at risk for progressing to noninsulin-dependent diabetes mellitus |
US5444086A (en) * | 1994-03-31 | 1995-08-22 | American Home Products Corporation | Naphthalenylmethyl thiophenones as antihyperglycemic agents |
-
1998
- 1998-03-24 IL IL13203298A patent/IL132032A0/xx unknown
- 1998-03-24 JP JP54585198A patent/JP2001521551A/ja active Pending
- 1998-03-24 BR BR9808054-7A patent/BR9808054A/pt not_active Application Discontinuation
- 1998-03-24 AU AU65763/98A patent/AU6576398A/en not_active Abandoned
- 1998-03-24 NZ NZ337927A patent/NZ337927A/xx unknown
- 1998-03-24 CN CN98805131A patent/CN1256630A/zh active Pending
- 1998-03-24 WO PCT/US1998/005591 patent/WO1998042340A1/en not_active Application Discontinuation
- 1998-03-24 CA CA002284192A patent/CA2284192A1/en not_active Abandoned
- 1998-03-24 KR KR1019997008746A patent/KR20010005678A/ko not_active Application Discontinuation
- 1998-03-24 EP EP98911919A patent/EP1019049A1/en not_active Withdrawn
-
1999
- 1999-09-22 NO NO994612A patent/NO994612L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP1019049A1 (en) | 2000-07-19 |
KR20010005678A (ko) | 2001-01-15 |
WO1998042340A1 (en) | 1998-10-01 |
CN1256630A (zh) | 2000-06-14 |
NZ337927A (en) | 2000-11-24 |
NO994612L (no) | 1999-11-24 |
CA2284192A1 (en) | 1998-10-01 |
NO994612D0 (no) | 1999-09-22 |
IL132032A0 (en) | 2001-03-19 |
JP2001521551A (ja) | 2001-11-06 |
AU6576398A (en) | 1998-10-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |