BR9808054A - Método de tratamento e/ou prevenção de diabete melito não-dependente de insulina e composição - Google Patents

Método de tratamento e/ou prevenção de diabete melito não-dependente de insulina e composição

Info

Publication number
BR9808054A
BR9808054A BR9808054-7A BR9808054A BR9808054A BR 9808054 A BR9808054 A BR 9808054A BR 9808054 A BR9808054 A BR 9808054A BR 9808054 A BR9808054 A BR 9808054A
Authority
BR
Brazil
Prior art keywords
insulin
prevention
treatment
dependent diabetes
composition
Prior art date
Application number
BR9808054-7A
Other languages
English (en)
Inventor
Magnus Pfahl
Waldemar Lernhardt
Andrea Fanjol
Original Assignee
Galderma Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Galderma Res & Dev filed Critical Galderma Res & Dev
Publication of BR9808054A publication Critical patent/BR9808054A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Physical Vapour Deposition (AREA)

Abstract

<B>"MéTODO DE TRATAMENTO E/OU PREVENçãO DE DIABETE MELITO NãO-DEPENDENTE DE INSULINA E COMPOSIçãO"<D> A presente invenção refere-se a métodos para o tratamento e/ou prevenção de diabete melito não dependente de insulina (NIDDM) em sujeitos que tenham desenvolvido ou estejam em risco substancial de desenvolvimento de NIDDM, através da utilização de compostos retinóides específicos que são estruturalmente relacionados com ácido 9-cis retinóide, que induz a diferenciação de pré-adipócitos em adipócitos. Tais compostos podem ser administrados isoladamente ou em combinação com outros agentes anti-diabetogênicos, tais como tiazolidinadionas.
BR9808054-7A 1997-03-24 1998-03-24 Método de tratamento e/ou prevenção de diabete melito não-dependente de insulina e composição BR9808054A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3560497P 1997-03-24 1997-03-24
PCT/US1998/005591 WO1998042340A1 (en) 1997-03-24 1998-03-24 Retinoid related molecules for the treatment of non-insulin dependent diabetes mellitus

Publications (1)

Publication Number Publication Date
BR9808054A true BR9808054A (pt) 2000-11-07

Family

ID=21883695

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9808054-7A BR9808054A (pt) 1997-03-24 1998-03-24 Método de tratamento e/ou prevenção de diabete melito não-dependente de insulina e composição

Country Status (11)

Country Link
EP (1) EP1019049A1 (pt)
JP (1) JP2001521551A (pt)
KR (1) KR20010005678A (pt)
CN (1) CN1256630A (pt)
AU (1) AU6576398A (pt)
BR (1) BR9808054A (pt)
CA (1) CA2284192A1 (pt)
IL (1) IL132032A0 (pt)
NO (1) NO994612L (pt)
NZ (1) NZ337927A (pt)
WO (1) WO1998042340A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9915285A (pt) * 1998-11-12 2001-08-07 Smithkline Beecham Plc Composição farmacêutica para liberação modificada de um sensitivador de insulina e um outro agente antidiabético
AR023699A1 (es) * 1998-11-12 2002-09-04 Smithkline Beecham Corp Una composicion farmaceutica que comprende un estabilizador de insulina y un procedimiento para preparar una composicion farmaceutica
US20020198203A1 (en) * 2001-06-07 2002-12-26 Wyeth Combination of a PTPase inhibitor and a thiazolidinedione agent
CN1921843A (zh) * 2004-01-23 2007-02-28 独立行政法人科学技术振兴机构 含视黄酸的糖尿病治疗药
WO2015109231A1 (en) * 2014-01-17 2015-07-23 Cornell University Methods of treating metabolic syndrome related conditions using retinoic acid receptor agonists
US11191755B2 (en) 2014-01-17 2021-12-07 Cornell University Compositions and methods for providing cardioprotective effects

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU647735B2 (en) * 1989-03-08 1994-03-31 University Of Virginia Alumni Patents Foundation, The Dietary supplement for insulin-resistant diabetics
FR2695317B1 (fr) * 1992-09-07 1995-03-10 Monal Lab Composition apte à stimuler la sécrétion d'insuline destinée au traitement du diabète non insulino-dépendant.
AU676227B2 (en) * 1993-01-22 1997-03-06 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Therapeutic agent for NIDDM
US5457109A (en) * 1993-09-15 1995-10-10 Warner-Lambert Company Use of thiazolidinedione derivatives and related antihyperglycemic agents in the treatment of disease states at risk for progressing to noninsulin-dependent diabetes mellitus
US5444086A (en) * 1994-03-31 1995-08-22 American Home Products Corporation Naphthalenylmethyl thiophenones as antihyperglycemic agents

Also Published As

Publication number Publication date
EP1019049A1 (en) 2000-07-19
KR20010005678A (ko) 2001-01-15
WO1998042340A1 (en) 1998-10-01
CN1256630A (zh) 2000-06-14
NZ337927A (en) 2000-11-24
NO994612L (no) 1999-11-24
CA2284192A1 (en) 1998-10-01
NO994612D0 (no) 1999-09-22
IL132032A0 (en) 2001-03-19
JP2001521551A (ja) 2001-11-06
AU6576398A (en) 1998-10-20

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]