ES2145517T3 - Nuevos derivados monofuncionalizados de edta, dtpa y ttha y su utilizacion en el diagnostico y en la terapia medicinales. - Google Patents

Nuevos derivados monofuncionalizados de edta, dtpa y ttha y su utilizacion en el diagnostico y en la terapia medicinales.

Info

Publication number
ES2145517T3
ES2145517T3 ES96946110T ES96946110T ES2145517T3 ES 2145517 T3 ES2145517 T3 ES 2145517T3 ES 96946110 T ES96946110 T ES 96946110T ES 96946110 T ES96946110 T ES 96946110T ES 2145517 T3 ES2145517 T3 ES 2145517T3
Authority
ES
Spain
Prior art keywords
monofunctionalized
new
derivatives
ttha
dtpa
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96946110T
Other languages
English (en)
Inventor
Johannes Platzek
Peter Mareski
Ulrich Niedballa
Bernd Raduchel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Application granted granted Critical
Publication of ES2145517T3 publication Critical patent/ES2145517T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/10—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings
    • C07C229/16—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings to carbon atoms of hydrocarbon radicals substituted by amino or carboxyl groups, e.g. ethylenediamine-tetra-acetic acid, iminodiacetic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Toxicology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

LA INVENCION TRATA DE NUEVOS DERIVADOS DE ACIDO ETILENODIAMINTETRAACETICO, ACIDO DIETILENOTRIAMINPENTAACETICO Y ACIDO TRIETILENOTETRAAMINHEXAACETICO MONOFUNCIONALIZADOS, DE SU PRODUCCION Y SU USO EN LA FABRICACION DE MEDIOS FARMACEUTICOS.
ES96946110T 1996-01-04 1996-12-20 Nuevos derivados monofuncionalizados de edta, dtpa y ttha y su utilizacion en el diagnostico y en la terapia medicinales. Expired - Lifetime ES2145517T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19601060A DE19601060C2 (de) 1996-01-04 1996-01-04 Neue monofunktionalisierte EDTA-, DTPA- und TTHA-Derivate und deren Verwendung in der medizinischen Diagnostik und Therapie

Publications (1)

Publication Number Publication Date
ES2145517T3 true ES2145517T3 (es) 2000-07-01

Family

ID=7782685

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96946110T Expired - Lifetime ES2145517T3 (es) 1996-01-04 1996-12-20 Nuevos derivados monofuncionalizados de edta, dtpa y ttha y su utilizacion en el diagnostico y en la terapia medicinales.

Country Status (12)

Country Link
US (1) US6080785A (es)
EP (1) EP0871608B1 (es)
JP (1) JP3993235B2 (es)
AT (1) ATE191456T1 (es)
AU (1) AU1870397A (es)
CA (1) CA2241825C (es)
DE (2) DE19601060C2 (es)
ES (1) ES2145517T3 (es)
GR (1) GR3033822T3 (es)
NO (1) NO322888B1 (es)
PT (1) PT871608E (es)
WO (1) WO1997025305A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7405320B2 (en) * 1998-06-22 2008-07-29 Immunomedics, Inc. Therapeutic and diagnostic conjugates for use with multispecific antibodies
WO2000058266A1 (en) * 1999-03-26 2000-10-05 Mallinckrodt Inc. Divergent method for the synthesis of diethylene triaminepenta aceticacid esters
AU4019100A (en) * 1999-03-26 2000-10-16 Mallinckrodt, Inc. Dtpa esters with orthogonal removable protecting groups
AU3766000A (en) * 1999-03-26 2000-10-16 Mallinckrodt, Inc. Method for the synthesis of non-symmetrical dtpa compounds
JP2001114792A (ja) * 1999-10-12 2001-04-24 Nihon Medi Physics Co Ltd ビスホスホン酸誘導体およびその放射性核種標識体
FR2809002B1 (fr) * 2000-05-18 2003-01-24 Oreal Utilisation de derives de l'acide n,n'-dibenzyl ethylene diamine n,n'-diacetique comme agent anti-pollution
PL359292A1 (en) 2000-09-29 2004-08-23 Anormed Inc. Process for preparation of n-1 protected n ring nitrogen containing cyclic polyamines and products thereof
JP5004438B2 (ja) * 2005-06-09 2012-08-22 行政院原子能委員会核能研究所 Ｄｔｐａ誘導体の製造方法
US8168296B2 (en) * 2007-02-07 2012-05-01 Air Products And Chemicals, Inc. Benzylated polyalkylene polyamines and uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1076146A (en) * 1963-06-05 1967-07-19 Sinclair Research Inc Lubricant compositions
GB1453694A (en) * 1972-08-25 1976-10-27 Shoe & Allied Trades Res Ass Stabilization of polymeric materials against hydrolysis
DE3806795A1 (de) * 1988-02-29 1989-09-07 Schering Ag Polymer-gebundene komplexbildner, deren komplexe und konjugate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel
DE19508058A1 (de) * 1995-02-21 1996-08-22 Schering Ag Verfahren zur Herstellung von DTPA-Tetraestern der terminalen Carbonsäuren und deren Verwendung zur Herstellung pharmazeutischer Mittel
US5618513A (en) * 1995-06-07 1997-04-08 Mallinckrodt Medical, Inc. Method for preparing radiolabeled peptides

Also Published As

Publication number Publication date
AU1870397A (en) 1997-08-01
WO1997025305A1 (de) 1997-07-17
DE19601060A1 (de) 1997-07-10
JP3993235B2 (ja) 2007-10-17
DE59604919D1 (de) 2000-05-11
EP0871608B1 (de) 2000-04-05
DE19601060C2 (de) 2002-04-25
NO983103L (no) 1998-07-03
JP2000502715A (ja) 2000-03-07
NO983103D0 (no) 1998-07-03
NO322888B1 (no) 2006-12-18
CA2241825C (en) 2005-09-27
ATE191456T1 (de) 2000-04-15
CA2241825A1 (en) 1997-07-17
GR3033822T3 (en) 2000-10-31
EP0871608A1 (de) 1998-10-21
US6080785A (en) 2000-06-27
PT871608E (pt) 2000-07-31

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